scholarly journals The association between Gastric Bacterial Infection and Low Level of Vitamin D among Patients with type 2 Diabetes Mellitus

2021 ◽  
Vol 2 (01) ◽  
pp. 38-46
Author(s):  
Sarah T. Al-Mofarji ◽  
Haider .K. Hussien ◽  
Nadira Salman Mohamed ◽  
Sundus Fadhil Hantoosh ◽  
Mohammed Khudier Abass ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Vitamin D ◽  
Type 2 Diabetes Mellitus ◽  
Fasting Blood Glucose ◽  
Diabetic Group ◽  
Diabetic Patients ◽  
Vitamin D Levels ◽  
H Pylori

Objectives: The present research aimed to find an association between infection by  Helicobacter pylori and vitamin D deficiency in type 2 diabetes mellitus among Iraqi individuals attending Al-Yarmouk Teaching Hospital. Methods: According to fasting blood glucose,  the samples were divided into a non-diabetic group with ten diabetic individuals and a diabetic group with thirty individuals. Results: The anti-H. Pylori (IgG) levels were 86.77± 58.62 NTU/µL in diabetic patients compared with 10.12 ± 7.40 NTU/µL in non- diabetic group. Vitamin D levels were decreased significantly in infected patients compared to non-infected subjects. Conclusion: The H pylori-infected patients have recorded the lowest level of vitamin D than non-infected individuals.

Association of Vitamin D Levels and type 2 Diabetes Mellitus in Asian Indians is Independent of Obesity

2018 ◽  
Vol 126 (09) ◽  
pp. 553-558 ◽  
Author(s):  
A. Gupta ◽  
M. Aslam ◽  
S. Rathi ◽  
B. Mishra ◽  
S. Bhardwaj ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Vitamin D ◽  
Type 2 Diabetes Mellitus ◽  
Asian Indian ◽  
Asian Indians ◽  
Diabetic Group ◽  
Vitamin D Levels ◽  
Significant Difference

Abstract Background A large proportion of subjects with type 2 diabetes mellitus (T2DM) in India are non-obese. Asian-Indian subjects with diabetes have been shown to have low vitamin D levels. Whether low vitamin D levels and T2DM in Asian-Indians is attributable to the associated obesity as in caucasians is unclear. Hence we studied the association of vitamin D levels and T2DM in Asian-Indians with or without obesity. Methods Total of 213 subjects were recruited in four groups, group 1-Non-obese diabetic, group 2-Non-obese non-diabetic, group 3-Obese diabetic and group 4-Obese non-diabetic. Subjects recruited under various groups were matched for age and sex. Anthropometry, skin-fold thickness, fasting and postprandial plasma glucose, HbA1c, fasting insulin, lipids and vitamin D levels were measured in all study subjects and were compared between the groups. Results Mean age of study population was 41.23±7.43 years. Mean BMI in groups 1,2,3 and 4 was 21.34±1.41, 20.53±2.27, 27.72±2.94 and 27.62±3.37 kg/m2 respectively. Overall 64.3% study subjects had vitamin D deficiency and 27.7% had insufficient vitamin D levels. Significantly lower vitamin D levels were found in diabetic groups 1 and 3 compared to non-diabetic groups 2 and 4. No significant difference was observed in vitamin D levels between groups 1 and 3. Similarly, no significant difference was observed in vitamin D levels between groups 2 and 4. Vitamin D levels did not show any significant correlation with BMI, waist or body fat. Conclusion Vitamin D levels do not appear to be related to obesity in diabetic as well non-diabetic Asian-Indian individuals.

scholarly journals The impact of vitamin D level on serum lipids in type 2 diabetes mellitus

2021 ◽  
Vol 2 (04) ◽  
pp. 230-236
Author(s):  
Zainab Subber ◽  
Hashim Hashim ◽  
Ghassan Al-Shamma
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Vitamin D ◽  
Type 2 Diabetes Mellitus ◽  
Serum Lipids ◽  
Fasting Blood Glucose ◽  
The Body ◽  
Diabetic Group ◽  
The Impact

Background: Vitamin D is considered an important regulator of many metabolic processes in the body. Its deficiency was reported to associate with many pathological conditions, with contradicting reports on its role in dyslipidemia. Objectives: To evaluate the role of vitamin D (total and/or free) in improving dyslipidemia of type 2 diabetes mellitus (T2DM). Methods: Sixty-four patients with T2DM, and 73 apparently healthy normal subjects were enrolled in the study from March to October 2020. Their fasting blood glucose, glycated hemoglobin, HbA1c, and serum lipids (cholesterol, its fractions and triglycerides) were measured in addition to total and free vitamin D. Results: There was a significant negative correlation between total vitamin D and each of cholesterol and LDL-C in the diabetic group. The correlations between serum vitamin D and all other lipid parameters (HDL-C, VLDL-C and triglycerides) were non-significant in the diabetic group, while in the control groups none of serum lipids showed significant correlations with vitamin D. Conclusions: The significant negative association of vitamin D with total cholesterol and LDLC in the diabetics reveals the important action of vitamin D in reducing the atherogenic indices, and consequent reduction in the rate of atherosclerosis and cardiovascular disease or stroke.

Prevalence of Toenail Onychomycosis in Patients with Type 2 Diabetes Mellitus and Evaluation of Risk Factors

2011 ◽  
Vol 101 (1) ◽  
pp. 49-54 ◽  
Author(s):  
Aynur Gulcan ◽  
Erim Gulcan ◽  
Sukru Oksuz ◽  
Idris Sahin ◽  
Demet Kaya
Keyword(s):  
Diabetes Mellitus ◽  
Risk Factors ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Fasting Blood Glucose ◽  
Diabetic Patients ◽  
Essential Components ◽  
Patients With Diabetes ◽  
Epidemiologic Risk

Background: We sought to determine the frequency of toenail onychomycosis in diabetic patients, to identify the causative agents, and to evaluate the epidemiologic risk factors. Methods: Data regarding patients’ diabetic characteristics were recorded by the attending internal medicine clinician. Clinical examinations of patients’ toenails were performed by a dermatologist, and specimens were collected from the nails to establish the onycomycotic abnormality. All of the specimens were analyzed by direct microscopy and culture. Results: Of 321 patients with type 2 diabetes mellitus, clinical onychomycosis was diagnosed in 162; 41 of those diagnoses were confirmed mycologically. Of the isolated fungi, 23 were yeasts and 18 were dermatophytes. Significant correlations were found between the frequency of onychomycosis and retinopathy, neuropathy, obesity, family history, and duration of diabetes. However, no correlation was found with sex, age, educational level, occupation, area of residence, levels of hemoglobin A1c and fasting blood glucose, and nephropathy. The most frequently isolated agents from clinical specimens were yeasts. Conclusions: Long-term control of glycemia to prevent chronic complications and obesity and to promote education about the importance of foot and nail care should be essential components in preventing onychomycosis and its potential complications, such as secondary foot lesions, in patients with diabetes mellitus. (J Am Podiatr Med Assoc 101(1): 49–54, 2011)

scholarly journals Fenofibrate decreased microalbuminuria in the type 2 diabetes patients with hypertriglyceridemia

2020 ◽  
Author(s):  
Xiaomeng Sun ◽  
Jia Liu ◽  
Guang Wang
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Treatment Group ◽  
Glycosylated Hemoglobin ◽  
Fasting Blood Glucose ◽  
Control Group ◽  
Diabetic Patients ◽  
Fenofibrate Treatment

Abstract Background: This study was to research the efficacy of fenofibrate in the treatment of microalbuminuria in the patients with type 2 diabetes mellitus (T2DM) and hypertriglyceridemia. Methods: Type 2 diabetic patients (56) with microalbuminuria and hypertriglyceridemia aged 30 to 75 were randomly divided into the fenofibrate treatment group(n=28) and the control group (n=28) for 180 days. Urinary microalbumin /creatinine ratio (UACR) and other metabolic parameters were compared at baseline, during treatment and after treatment. Results: After 180 days, the reduction of levels of fasting blood glucose (FBG) and glycosylated hemoglobin (HbA1c) in two groups were no differences. In treatment group, uric acid (UA) (296.42 ± 56.41 vs 372.46 ± 72.78), triglyceride (TG) [1.51(1.17, 2.06) vs 3.04(2.21, 3.29)], and UACR [36.45 (15.78,102.41) vs 129.00 (53.00, 226.25)] were significantly decreased compared with the baseline. The high-density lipoprotein cholesterol (HDL-C) levels were significantly increased (1.22 ± 0.26 vs 1.09 ± 0.24) compared with the baseline. The decrease in UACR [-44.05(-179.47, -12.16) vs -8.15(-59.69, 41.94)]in treatment group was significantly higher compared with the control group. The decrease in UACR was positively associated with the decreases in TG ( r = 0.447, P = 0.042) and UA ( r = 0.478, P = 0.024) after fenofibrate treatment. Conclusion: In the patients with hypertriglyceridemia and type 2 diabetes mellitus, fenofibrate can improve microalbuminuria and do not increase the deterioration of glomerular filtration rate

scholarly journals Association of serum vitamin D and parathormone levels in patients of type 2 diabetes mellitus with diabetic retinopathy

2017 ◽  
Vol 10 (2) ◽  
pp. 61
Author(s):  
Mohammad Shiblee Zaman ◽  
Md. Matiur Rahman ◽  
Subrata Kumar Biswas ◽  
Md. Mozammel Hoque ◽  
Khondakar Alwan Nahid
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Vitamin D ◽  
Type 2 Diabetes Mellitus ◽  
Diabetic Retinopathy ◽  
Vitamin D Deficiency ◽  
Diabetic Patients ◽  
Control Serum ◽  
25 Hydroxy Vitamin D

<p>The present study was aimed to evaluate the association of serum 25-hydroxy vitamin D and parathormone in 46 patients of type 2 diabetes mellitus with diabetic retinopathy [non-proliferative, (n=27); proliferative (n=19)]. Twenty one diabetic patients without retinopathy were taken as control. Serum 25-hydroxy vitamin D and intact parathyroid hormone were measured by chemiluminescence microparticle immunoassay. Concentration of 25-hydroxy vitamin D differed significantly among groups (p=0.018) and it was significantly lower in proliferative diabetic retinopathy than no diabetic retinopathy (p=0.003). Logistic regression analysis revealed that vitamin D deficiency [25-hydroxy vitamin D &lt;20 ng/mL] was indepen-dently associated with development of diabetic retinopathy (p=0.007, OR 20.90, 95%CI 2.33-187.23). In conclusion, vitamin D deficiency is associated with diabetic retinopathy complicating type 2 diabetes mellitus.</p>

scholarly journals Hubungan Antara kadar Vitamin D dengan HbA1c pada Pasien Diabetes Mellitus Tipe 2 di Laboratorium Klinik Thamrin Medan Tahun 2019

2020 ◽  
Vol 2 (1) ◽  
pp. 8-12
Author(s):  
Desi Novita ◽  
Meida Nugrahalia ◽  
Ida Fauziah
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Vitamin D ◽  
Type 2 Diabetes Mellitus ◽  
Clinical Laboratory ◽  
Glucose Binding ◽  
Vitamin D Levels ◽  
Sugar Levels ◽  
The Relationship

Vitamin D as an immunomodulator play an important role in controlling glycemic levels and reducing the risk of diabetes. HbA1c as a substance formed from glucose binding with hemoglobin which has a good relationship with average blood sugar levels of fasting, daily and 3 months. This research was conducted to determine the relationship between vitamin D levels and HbA1c in patients with type 2 diabetes mellitus. This research used descriptive methods and the research samples were all patients who suffer from type 2 diabetes mellitus in the clinical laboratory of Thamrin Medan. Data were obtained by checking vitamin D and HbA1c levels in patients blood serum. The number of samples in this research were 47 people. The results of this research indicate that there is a very weak relationship between vitamin D levels and HbA1c, with r = 0,225 and R = 5,1%, therefore, it was clearly presented that effect of vitamin D on HbA1c is 5,1%.

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