scholarly journals A Pharmacognostical and Phytochemical study of Kanchanara Gutika

2020 ◽  
Vol 11 (4) ◽  
pp. 685-689
Author(s):  
Gnana Prasuna S ◽  
Manu Rajagopal ◽  
Pavan Kumar S ◽  
Harinatha Chary B
Keyword(s):  
Physicochemical Analysis ◽  
Water Soluble ◽  
Dissolution Time ◽  
Vascular Bundles ◽  
Good Clinical Outcome ◽  
Phytochemical Study ◽  
Minimum Quality Standards ◽  
Phytochemical Studies ◽  
Layer Chromatography ◽  
Minimum Quality

Kanchanara gutika is one of the preparations of the Ayurveda, which is used for the treatment of the Thyroid disorders. It is in use since many years with good clinical outcome. But the pharmacognostic and phytochemical studies of the drug has not been carried out yet. Hence to study them this study is planned.  Aim: Authentication of the raw drugs of Kanchanara gutika and phytochemical evaluation of the finished product.  Materials and methods: The present study deals with the Pharmacognostical identification of the ingredients of Kanchanara Gutika and its physicochemical analysis. Thin Layer chromatography study (TLC) was also developed.Results: Pharmacognostical results showed Pippali catkin with fruit, Maricha with the epicarp and the oil globules, Sunti with oleoresins and vascular bundles, Haritaki with fibres, Amlaki with epicarp and mesocarp, Vibhithaki with stone cells and Kanchanara with xylem and phloem vessels. Qualitative studies shows that Loss of drying 33%, PH 4.72%, Water soluble matter 12%, Alcohol soluble matter 19%, Total ash 3%, Acid insoluble ash 2.5%, Dissolution time 4%, Moisture content 8%. The TLC chromatograph showed five bands at Rf 0.21(Yellow), 0.28 (Grey), 0.47 (Brown), 0.56 (Violet), 0.93 (Orange).Conclusion: Pharmacognostical study revealed genuinity of raw drugs. Physicochemical and TLC studies inferred that the formulation meets the minimum quality standards. The inference from this study may be used as reference standard in the further quality control researches. 

scholarly journals PRELIMINARY PHARMACOGNOSTICAL, PHYTOCHEMICAL STUDY AND HPTLC ANALYSIS OF COSTUS PICTUS D.DON.

2021 ◽  
pp. 11-24
Author(s):  
Hasna.T ◽  
Vivek.P ◽  
Manojkumar.N
Keyword(s):  
Water Extract ◽  
Ethanolic Extract ◽  
Cost Effective ◽  
Water Soluble ◽  
Vascular Bundles ◽  
Classical Literature ◽  
Phytochemical Study ◽  
Parenchyma Cells ◽  
Rf Values ◽  
Phytochemical Studies

The ancient wisdom in Ayurveda medicine is still not exhaustively explored. Multiple exotic plants existent in India which are not described in classical literature of Ayurveda are commonly referred to as Anukta Dravya (undocumented). Costus pictus D.Don is such a plant, recently introduced in India from Mexico, which is used for renal disorders there. In India, it is used in Diabetes mellitus. This is proven for antidiabetic, antioxidant, anticancerous, antimicrobial and diuretic actions. It is an easily propagated, palatable and cost effective plant. Identification through pharmacognostical and phytochemical studies is essential for the standardization of any plant. The green leaf is narrowly elliptic with 10 to 25cm length and 2.5 to 6cm width. Microscopy revealed presence of vascular bundles, unicellular trichomes in upper epidermis, thin walled parenchyma cells in ground tissue and layers of parenchymatous hypodermis. Powder microscopy showed presence of epidermal parenchyma cells with underlying chlorenchyma group of fibers and fibro vascular bundles.TLC photo documentation revealed presence of many phytoconstituents with different Rf values. Densitometric scan showed many peaks, 10 at 254nm, 11 at 366nm, 6 at 520nm and 9 at 620 nm after derivatisation. Moisture content was 20%. The percentage of total ash, acid insoluble ash, and water insoluble ash was determined. The water soluble extractive value was 22.57 which is highest among all the extracts. The results indicated the presence of alkaloid, steroids, tannins, flavanoids, phenol, carbohydrate and resin in ethanolic extract and steroid, flavanoids, phenols, saponins, tannins and glycosides in water extract.

scholarly journals A Pharmacognostical and Phytochemical study of Sookshma Eladi Choornam

2020 ◽  
Vol 11 (4) ◽  
pp. 712-715
Author(s):  
Harinatha Chary B ◽  
Manu Rajagopal ◽  
Pavan Kumar S ◽  
Gnana Prasuna S
Keyword(s):  
Thin Layer ◽  
Thin Layer Chromatography ◽  
Large Scale ◽  
Fine Powder ◽  
Chemical Study ◽  
Quality Parameters ◽  
Water Soluble ◽  
Dissolution Time ◽  
Phytochemical Study ◽  
Layer Chromatography

Introduction: Sookshma Eladi choornam is one of the Ayurvedic formulations specially mentioned for Kaphaja Hridroga in Hridroga prakarana of Bhaishajya Ratnavali.  Dhamani pratichaya (Atherosclerosis) is one of the diseases of Kaphaja nanatmaja vaydhi which is the more important cause for Ischemic Heart Disease. The cause for Atherosclerosis could be Hyperlipidemias. Eladi choornam is a compound preparation which contains powders of Sookshma ela (Elettaria cardamomum Maton.) and Pippali moolam (root of Piper longum L.,). As these drugs are Katu vipaka in nature they can be used in Hyerlipidemia.  To know the efficacy of the drugs their quality parameters are highly essential to manufacture in the large scale. Method: The present study deals with the Pharmacognostical and phyto-chemical study of Sookshma eladi choornam including Thin Layer chromatography study (TLC) as per the standard literature. Result: Consistency of Sookshma eladi choornam is fine powder. Colour was brown, odour was aromatic spicy smell, Taste was pungent, touch was smooth powder form,  Qualitative study showed that pH is 4.9, total ash value 12 %, loss on drying is 4.5%, Water soluble matter17%, Alcohol soluble matter 8%,  Acid insoluble ash 8.5%. Thin Layer chromatography (TLC) revealed one yellow spot.  Dissolution time is 4 minutes and Moisture content was 8%. Phytochemicals as Alkaloids, Glycosides, Tannins, Flavonoids and Phenols were found. Conclusion: Pharmacognostical, phyto-chemical and TLC studies inferred that the formulation meets the minimum quality standards. The study may be used as reference standard in the further quality control researches.

Pharmacognostic studies of Morinda brevipes S. Y. Hu

2019 ◽  
Vol 48 (3) ◽  
pp. 401-407
Author(s):  
Rong Li ◽  
Xiaojing Lin ◽  
Genqiu Tang ◽  
Junni Li ◽  
Dong Wang ◽  
...  
Keyword(s):  
Calcium Oxalate ◽  
Transverse Section ◽  
Volatile Oils ◽  
Needle Crystal ◽  
Cork Cell ◽  
Registration Number ◽  
Phytochemical Studies ◽  
First Time ◽  
Layer Chromatography ◽  
Inequality Type

DNA barcoding of ITS and psbA-trnH regions, histochemistry as well as thin layer chromatography (TLC) of Morinda brevipes S.Y. Hu were analyzed. Transverse section of root revealed the presence of cortex, xylem, cork cell, stone cells, and calcium oxalate sandy crystal. The lower epidermis cells showed many stoma in paracytic or inequality type. Spiral vessel and tiny calcium oxalate needle crystal usually appeared in the powder. TLC showed the presence of emodin in M. brevipes. Phytochemical studies revealed the existence of carbohydrates, saponins, tannins, flavones, anthraquinones, alkaloids and volatile oils. The ITS and psbAtrnH sequences were found for the first time which were submitted to NCBI to obtain the GenBank registration number. This study might play an important role in the identification, and utilization of M. brevipes for various purposes.

scholarly journals Phytochemical studies and thin layer chromatography of leaves and flower extracts of Senna siamea lam for possible biomedical applications

2015 ◽  
Vol 7 (3) ◽  
pp. 18-26 ◽  
Author(s):  
Adamu Hassan Ismail ◽  
Abdullahi Nasiru Idris ◽  
Muhammed Malut Amina ◽  
Abdulkadir S Ibrahim ◽  
Sani Ali Audu
Keyword(s):  
Thin Layer ◽  
Thin Layer Chromatography ◽  
Biomedical Applications ◽  
Senna Siamea ◽  
Phytochemical Studies ◽  
Layer Chromatography

scholarly journals Solid-state studies and antioxidant properties of the γ-cyclodextrin·fisetin inclusion compound

2017 ◽  
Vol 13 ◽  
pp. 2138-2145 ◽  
Author(s):  
Joana M Pais ◽  
Maria João Barroca ◽  
Maria Paula M Marques ◽  
Filipe A Almeida Paz ◽  
Susana S Braga
Keyword(s):  
Inclusion Compound ◽  
Antioxidant Properties ◽  
Physicochemical Analysis ◽  
Water Soluble ◽  
Solid Inclusion ◽  
Human Consumption ◽  
X Ray Diffraction ◽  
Wide Range ◽  
Soluble Solid ◽  
Cp Mas Nmr

Fisetin is a natural antioxidant with a wide range of nutraceutical properties, including antidiabetic, neuroprotecting, and suppression or prevention of tumors. The present work describes the preparation of a water-soluble, solid inclusion compound of fisetin with gamma-cyclodextrin (γ-CD), a cyclic oligosaccharide approved for human consumption. A detailed physicochemical analysis of the product is carried out using elemental analysis, powder X-ray diffraction (PXRD), Raman, infrared and 13C{1H} CP-MAS NMR spectroscopies, and thermal analysis (TGA) to verify fisetin inclusion and to present a hypothetical structural arrangement for the host–guest units. The antioxidant activity of the γ-CD·fisetin inclusion compound is evaluated by the DPPH assay.

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