Evaluation of Acupuncture Combined with Rehabilitation Therapy on Neurological Function Recovery in Patients with Cerebral Infarction

2021 ◽  
Keyword(s):  
Cerebral Infarction ◽  
Neurological Function ◽  
Rehabilitation Therapy ◽  
Function Recovery

scholarly journals Early path nursing on neurological function recovery of cerebral infarction

2019 ◽  
Vol 10 (1) ◽  
pp. 160-163
Author(s):  
Ling Chen ◽  
Zhena Han ◽  
Junjie Gu
Keyword(s):  
Cerebral Infarction ◽  
Conventional Treatment ◽  
Neurological Function ◽  
Early Rehabilitation ◽  
Control Group ◽  
P Value ◽  
Treatment Methods ◽  
Rehabilitation Care ◽  
Function Recovery ◽  
Experimental Group

Abstract Purpose to study the application of path type early rehabilitation nursing in the nursing of patients with cerebral infarction and to explore its impact on the recovery of neurological function. Methods Patients with acute cerebral infarction in our hospital were randomly divided into two groups. The control group used conventional treatment methods. The experimental group used path type early rehabilitation care based on conventional treatment methods and observed the curative effect. ResultsThe NIHSS scores in the experimental group were significantly lower than those in the control group, and the P value was less than 0.05, which was statistically significant. Conclusion Path type early rehabilitation nursing has a positive effect on the treatment of patients with cerebral infarction, which contributes to the recovery of neurological function of patients and is worthy of promotion in treatment.

scholarly journals Effect of Hip Fracture on Prognosis of Acute Cerebral Infarction

BioMedica ◽  
2021 ◽  
Vol 37 (2) ◽  
pp. 114-118
Author(s):  
Jiawen Yuan ◽  
Gang Zhu ◽  
Yuwu Zhao ◽  
Jiankang Huang
Keyword(s):  
Surgical Treatment ◽  
Hip Fracture ◽  
Mortality Rate ◽  
Cerebral Infarction ◽  
Recovery Rate ◽  
Neurological Function ◽  
Acute Cerebral Infarction ◽  
Control Group ◽  
Vein Thrombosis ◽  
Hospitalization Period

<p><strong>Background and Objective:</strong> The guidelines on the factors to determine whether a patient with concomitant stroke and hip fracture is a good candidate for surgical hip repair are still debatable. This study was carried out to investigate the relationship between the management of acute hip fracture and the recovery of neurological function and prognosis in patients with concomitant acute cerebral infarction.</p> <p><strong> Methods:</strong> Thirty patients with acute cerebral infarction combined with acute hip fracture, who were hospitalized and did not accept surgical treatment, and matched 60 cases as control group having acute cerebral infarction without hip fracture admitted in the same period were selected. The neurological function recovery, hospitalization period, 6 months recovery rate, frequency of complications, and 1 year mortality rate between the groups were compared.</p> <p><strong>Results: </strong>Compared with common acute cerebral infarction patients, the NIH Stroke Scale/Score of acute cerebral infarction group with hip fracture was higher (7.2 &plusmn; 5.4 vs. 5.6 &plusmn; 4.3, p = 0.034). The hospitalization period was prolonged (16.1 &plusmn; 8.9 vs. 12.2 &plusmn; 5.3, p = 0.041), and 6 months recovery rate was lower (26.7% vs. 53.3%, p = 0.016), the frequency of pulmonary infection and lower extremity deep vein thrombosis was higher (30% vs. 11.7%, p = 0.03; 6.7% vs. 0, p = 0.043). The 1-year mortality rate in patients with combined hip fracture was higher than in patients with cerebral infarction only.</p> <p><strong>Conclusion:</strong> Acute cerebral infarction combined with hip fracture lead to worse neurological recovery, prolonged hospitalization period, increased complications, decreased patient prognosis, and increased 1 year mortality. Surgical treatment of hip fracture with concomitant acute cerebral infarction may improve the prognosis of patients. According to the statistics of neurological function and mortality after 1 year of follow-up, the prognosis of patients with Modified Rankin Scale below 3 was considered good.</p>

scholarly journals Promoting functions of microRNA-29a/199B in neurological recovery in rats with spinal cord injury through inhibition of the RGMA/STAT3 axis

2020 ◽  
Vol 15 (1) ◽  
Author(s):  
Weijie Yang ◽  
Ping Sun
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Gray Matter ◽  
Rating Scale ◽  
Neurological Function ◽  
Neurological Recovery ◽  
Altered Expression ◽  
Stat3 Phosphorylation ◽  
Function Recovery ◽  
Cord Injury

Abstract Background The prognostic and therapeutic potential of microRNAs (miRNAs) in spinal cord injury (SCI) has aroused increasing concerns. This study aims to research the functions of miR-29a/199B in the neurological function recovery after SCI and the mechanical mechanism. Methods A rat model with SCI was induced with sham-operated ones as control. The locomotor function and coordination of rat hindlimbs were determined by a Basso, Beattie, and Bresnahan (BBB) locomotor rating scale and a ladder-climbing test, respectively. Expression of a neurofilament protein NF-200 and synaptophysin in gray matter of rats was determined to evaluate neuronal recovery in a cellular perspective. Binding relationships between miR-29a/199B with RGMA were predicted and validated using luciferase assays. Altered expression of miR-29a/199B and RGMA was introduced to explore their functions in rat neurological functions. The protein level and phosphorylation of STAT3 in gray matter were measured by western blot analysis. Results miR-29a and miR-199B were poorly expressed, while RGMA was abundantly expressed in gray matter at injury sites. Either miR-29a or miR-199B could bind to RGMA. Overexpression of miR-29a/199B or silencing of RGMA led to an increase in BBB locomotor scores, hindlimb coordination ability, and the expression of NF-200 and synaptophysin in gray matter. Further inhibition in miR-29a/199B blocked the promoting roles of RGMA silencing in neurological recovery. Upregulation of miR-29a/199B or downregulation of RGMA suppressed the phosphorylation of STAT3. Conclusion This study evidenced that miR-29a and miR-199B negatively regulated RGMA to suppress STAT3 phosphorylation, therefore promoting the neurological function recovery in rats following SCI.

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