scholarly journals Drug utilisation evaluation of antiplatelet agents in a tertiary care teaching hospital-a prospective observational study

2021 ◽  
pp. 218-229
Author(s):  
Rishitha Reddy P ◽  
Prathul P ◽  
Jayalakshmi A ◽  
Anusha SB ◽  
Randeep Raj V.C
Keyword(s):  
Observational Study ◽  
Prospective Observational Study ◽  
Tertiary Care ◽  
General Medicine ◽  
Antiplatelet Agents ◽  
Bleeding Risk ◽  
Prescribing Pattern ◽  
Co Morbidity ◽  
Social Habits ◽  
Ischemic Events

Background: Cardiovascular and cerebrovascular diseases were becoming predominant cause of morbidity and mortality in India. Antiplatelet agents remain as the cornerstone therapy for acute thrombotic coronary syndromes, IHD, STROKE, CHD and PCI and are essential for thromboprophylaxis. The current study was undertaken to evaluate the drug use pattern of antiplateletagents and to study the prescribing pattern, observe co-morbid conditions, social habits [alcohol/smoking], adverse events and drug-drug interactions associated with antiplatelet agents. Methods: A prospective observational study was conducted at MIMS hospital, study population of 160 inpatients from cardiology, general-medicine and neurology departments. Data was analyzed in Microsoft excel. Results: Data records obtained from 160 patients in which 51.87% were females followed by males 48.125%. most patients with IHD and stroke were found in age group 50-70 years. Hypertension was most found co-morbidity among the patients [61.88%] followed by diabetes [34.38%], hypothyroidism [5%], epilepsy[3.75%]. Utilisation pattern of antiplatelet agents aspirin, clopidogrel were found to be[97.5%] [82.5%] respectively. patients on DAPT[81%] were highest compared to monotherapy [19%]. Patients found with social habits were 38.75% smokers, 31.25% alcoholics and 22% both alcohol and smoking. Conclusion: The present study concludes that DAPT [aspirin+clopidogrel] was found to be superior to monotherapy, and incidence of IHD which is more common in males compared to females. Patients in the group 51-70 were most affected with stroke, IHD and with female predominance over male. Antiplatelet therapy which is clearly efficacious in reducing the incidence of ischemic events/ thromboembolic events DAPT[aspirin+ clopidogrel] was most effective and reduced ischemic events, yet have the risk of bleeding or resistance. Newer anti platelet agents such a Prasugrel and Ticagrelor can be utilised considering the bleeding risk.

scholarly journals A prospective observational study on prescribing patterns of drugs used in alcoholic liver disease patients at tertiary care teaching hospital

2017 ◽  
Vol 6 (6) ◽  
pp. 1386
Author(s):  
Zeebaish S. ◽  
Hemalatha P. ◽  
Eswari P. V. S. N. ◽  
Kodandaraman T. ◽  
Lakshmi P. ◽  
...  
Keyword(s):  
Liver Disease ◽  
Observational Study ◽  
Alcoholic Liver Disease ◽  
Prospective Observational Study ◽  
Tertiary Care ◽  
Specific Treatment ◽  
General Medicine ◽  
Prescribing Patterns ◽  
Informed Consent Form ◽  
The Right

Background: Rational drug prescribing can be defined as appropriate drugs prescribed in the right dose, at correct time intervals and for a sufficient duration. Alcoholic Liver Disease (ALD) and its complications are the principle cause for morbidity and mortality rate and accounts for elevated social and economic costs. The drug use will be a challenge for the physicians as there was no specific treatment for ALD, and decisions regarding treatment are critically depends on the symptoms and complications.Methods: A uni-centric prospective (observational) study was conducted for a period of 6months, to evaluate the current prescribing patterns used in treating ALD. All the patients admitted with diagnosis of ALD in General medicine department, both male and female medical wards were included in the study. General medicine outpatient department, special population such as pregnancy and psychiatry, patients below 18years and those who are not willing to sign in informed consent form was excluded from the study.Results: Number of males (98.02%) between age group 31-40years (29.6%) was more prone when compared to females (1.77%). Portal hypertension (30.35%) followed by jaundice (11.30%) and Ascites (10.71%) were frequently observed complications associated co-morbidities with ALD. WHO prescribing indicators showed deviation from there standard reference values. Diuretics (15.73%), antibiotics (13.14%), vitamin supplements (11.11%) and antacids (10.13%) categories were the most commonly prescribed for patients. The drugs prescribed from NLEM-2015 (82.11%) shows deviation from standard values.Conclusions: Futhermore, multi-centered studies should be conducted to draw best results on prescribing patterns of ALD in India.

scholarly journals A prospective observational study of prescription pattern in a tertiary care teaching hospital of Jharkhand

2019 ◽  
Vol 8 (12) ◽  
pp. 2620
Author(s):  
Abha Kumari ◽  
Keshav Kumar ◽  
Manju Gari ◽  
Kumari Pallavi ◽  
Subhankar Choudhury
Keyword(s):  
Observational Study ◽  
Prospective Observational Study ◽  
Care Delivery ◽  
Tertiary Care ◽  
Health Care Delivery System ◽  
World Health ◽  
Fixed Dose ◽  
Prescribing Pattern ◽  
Prescribing Practice ◽  
Health Organization

Background: Prescription error and irrational prescribing are the avoidable problems imposed on health care delivery system from prescriber side which must be addressed. Periodic prescription audit helps to curtail the error and irrational prescribing.Methods: A prospective observational study was conducted on patients visiting various Outpatient Department of RIMS, Ranchi, Jharkhand on all working days at 11:00 AM to 12:00 PM from 1 August 2018 to 31 July 2019. Various aspects of collected prescriptions were analyzed by using World Health Organization (WHO) prescribing indicators.Results: In this study, out of 700 prescriptions collected, 76 were excluded. Out of total 624 patients analyzed, 382 (61.28%) were male and 242 (38.72%) were female. 48 (7.69%) patients belonged to ≤18, 464 (74.36%) to 19-64 and 112 (17.95%) to ≥65 years of age group. Tablet (71%) was the most common dosage form. None of prescriptions were having registration number of the doctor. 242 (38.78%) prescriptions did not have a diagnosis duly written. The total no. of drugs prescribed in 624 prescriptions was 2176. Only 32 (5.13%) prescriptions were found to have medicines prescribed in block letters. Antibiotics (29%) were the most common class of drugs prescribed. Average number of drugs per prescription was 3.47. Only 48 (2.20%) drugs were prescribed by their generic name while total of injectables prescribed were 102 (4.68%). Total number of drugs from NLEM was 848 (38.97%). 196 (9.00%) drugs were fixed-dose combination.Conclusions: In our study, we found deficiencies in various parts of prescriptions. Prescribing pattern was not in accordance with WHO recommendation for prescribing practice.

scholarly journals Prescribing Pattern of Drugs Used in Chronic Liver Disease with Co Morbid Conditions and Assessment of Severity using MELD Score: A Prospective Observational Study

2020 ◽  
Vol 10 (5-s) ◽  
pp. 19-24
Author(s):  
Samreen Huma ◽  
Omer Nishat Fatima ◽  
Ishrath Ayesha ◽  
Jamal Mohammed Moiz ◽  
Shareef Mohammed Mohiuddin
Keyword(s):  
Liver Disease ◽  
Observational Study ◽  
Chronic Liver Disease ◽  
Prospective Observational Study ◽  
General Medicine ◽  
Meld Score ◽  
Chronic Liver ◽  
Prognostic Impact ◽  
Prescribing Pattern ◽  
Old Patients

Objectives: To study the prescribing pattern of drugs & its use in the treatment of CLD & assess the pattern of co-morbidities associated with CLD. To Study the mortality rate of the patient using MELD score at a department of general medicine at Osmania general Hospital to produce a result which would aid better rational drug use and improve quality of life. Methodology: A Prospective, observational study was carried out at OGH for a period of 6 months in 100 old patients. Population of either sex or ≥ 18 years of age were included. Conclusion: There is a considerable scope for improving prescribing pattern in CLD by minimizing the use, reduction of doses of drugs to reduce the consequence of hepatotoxicity and Antibiotic Resistance. The prognostic impact of individual comorbidities, on the other hand, may point to areas where cirrhosis and comorbid diseases interact. Studies of individual comorbidities may therefore improve our understanding of the pathophysiology of cirrhosis. MELD showed that the subjects were less likely to get a Liver transplant. Keywords: Chronic liver disease (CLD), Model for end stage liver disease (MELD), Diabetes Mellitus (DM), hypertension (HTN)

scholarly journals A prospective observational study of drug prescription pattern of antibiotics in diabetic foot ulcer in tertiary care teaching hospital

2020 ◽  
Vol 9 (7) ◽  
pp. 1020
Author(s):  
Kamalavarshini Paramasivamsasanger ◽  
Prema Mariappan ◽  
Dhivya Govindasamy ◽  
Padmavathi Karunakaran ◽  
Rajalakshmi Ramesh
Keyword(s):  
Observational Study ◽  
Diabetic Foot ◽  
Prospective Observational Study ◽  
Drug Prescription ◽  
Tertiary Care ◽  
Foot Ulcer ◽  
Diabetic Foot Ulcer ◽  
Prescribing Pattern ◽  
College Hospital ◽  
First Choice

Background: Our aim was to study a prescribing pattern of antibiotics used in diabetic foot ulcer (DFU).Methods: 50 patients were selected by inclusion and exclusion criteria basis. It was a prospective observational study conducted in Department of Surgery, Rajah Muthiah Medical College Hospital (RMMCH), Annamalai University.Results: This study reveals that male patients 60% are more prone to develop diabetic foot ulcer than the female patients 40%. Patients of 50 to 60 age group 32% has higher prevalence of DFU. The most commonly prescribed antibiotics are metronidazole 48% and cefotaxime 48% followed by piperacillin and tazobactam combination 30%, ciprofloxacin 20%, linezolid 18%, amoxicillin and clavulanic acid combination 12%, cefixime 6%, clindamycin 4%, amikacin 4%, faropenam 4%, ceftriaxone 2%, amoxicillin 2%, gentamicin 2%, cefoperazone sodium and sulbactam combination 2%.Conclusions: Lack of antibiotic sensitivity test leads to growth of organism, wrong antibiotic selection and irrational use of antibiotics. And also observed patient developed resistance to linezolid antibiotic when used as a first choice of drug to treat diabetic foot infection including methicillin-resistant Staphylococcus aureus (MRSA) infected patients.

scholarly journals Assessment of Prescription Pattern Among COPD Patients in Departments of General Medicine Ward and Pulmonology in Tertiary Care Hospitals of Khammam Region

2020 ◽  
Vol 11 (2) ◽  
pp. 1798-1806
Author(s):  
Sai Lakshmi Srikala T ◽  
Saika V ◽  
Raveendra Babu K ◽  
Chinna Eswaraiah M
Keyword(s):  
Tertiary Care ◽  
General Medicine ◽  
Symptomatic Treatment ◽  
Chronic Obstructive ◽  
Pulmonary Medicine ◽  
Care Hospital ◽  
Prescribing Pattern ◽  
Copd Patients ◽  
Co Morbidity ◽  
Study Population

Chronic obstructive pulmonary disease is a common preventable and treatable disease. It has been a leading cause of morbidity and mortality in industrialized and developing countries. Drug utilization research promotes the rational use of drugs and decreases adverse drug reactions in the population. The present study is aimed to analyze and evaluate the trends and patterns of prescribing drugs among COPD patients. A prospective observational study was conducted in 301 patients admitted in the general and pulmonary medicine departments over six months at a tertiary care hospital in Khammam region. Out of the 301 study population, male patients were more (81.39%).  The majority of the patients were from the age group of 51-60 years (30.56%). Smoking was found to be more prominent in the study population (63.6%). Bronchodilators (46.90%) were mostly prescribed class of drugs in the management of COPD followed by Systemic Corticosteroids (20.60%), Antibiotics (19.09%) Most common co-morbidity was found to be Hypertension (19.85%). The study concludes that symptomatic treatment was given to COPD patients in the hospital. The prescribing pattern was found to be in concordance with the current GOLD guidelines in the management of COPD patients

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