scholarly journals Korelasi Konsentrasi Kalsium Serum dengan Fungsi Paru pada Remaja di Makassar

2020 ◽  
Vol 13 (2) ◽  
pp. 98-102
Author(s):  
Ermida Sumardi ◽  
Arif Santoso ◽  
Andriany Qanitha

Abstrak. Penelitian ini bertujuan untuk mngetahui korelasi antara konsentrasi kalsium serum dengan fungsi paru pada remaja di SMA Sanur Makassar. Desain penelitian yang digunakan adalah cross sectional study. Populasi dan sampel dalam penelitian ini adalah remaja di SMA Sanur Makassar. Pengumpulan data menggunakan data primer dan data sekunder. Data dianalisis menggunakan analisis univariat dan bivariat. Hasil penelitian menunjukkan bahwa responden paling banyak adalah dengan konsentrasi kalsium serum > 9 mg/dl yaitu 66,67%, dan memiliki fungsi paru (KV) normal yaitu 73,68%, demikian dengan fungsi paru (KVP) normal yaitu 75,44%. Hasil uji statistik diperoleh nilai signifikansi 0,423 > 0,05, dan nilai F hitung 0,651 < F tabel 2,55, maka disimpulkan bahwa ada korelasi secara signifikan antara konsentrasi kalsium serum dengan fungsi paru (KV).   Kata kunci: Korelasi, kalsium serum, fungsi paru.   Correlation of Serum Calcium Concentration with Lung Function Adolescents in Makassar   Abstract. This study aims to determine the correlation between serum calcium concentration and lung function in adolescents at Sanur Makassar High School. The research design used was cross sectional study. The population and sample in this study were teenagers at Sanur Makassar High School. Data collection uses primary data and secondary data. Data were analyzed using univariate and bivariate analysis. The results showed that the most respondents were with serum calcium concentrations> 9 mg / dl that is 66.67%, and had normal lung function (KV) which was 73.68%, so with normal lung function (KVP) which was 75.44%. Statistical test results obtained a significance value of 0.423> 0.05, and a calculated F value of 0.651 <F table 2.55, it was concluded that there was a significant correlation between serum calcium concentration and pulmonary function (CV).   Keywords: Correlation, serum calcium, pulmonary function.

BMJ Open ◽  
2017 ◽  
Vol 7 (10) ◽  
pp. e018010 ◽  
Author(s):  
Ji Eun Soh ◽  
Kyung-Moon Kim ◽  
Ji-Won Kwon ◽  
Hyung Young Kim ◽  
Ju-Hee Seo ◽  
...  

BackgroundRelationship between recurrent wheeze and airway function and inflammation in preschool children is not fully known.ObjectiveTo investigate the relationship between recurrent wheeze and airway inflammation, lung function, airway hyper-reactivity (AHR) and atopy in preschool children.DesignObservational study, comparing forced expiratory volume in 1 s (FEV1), forced vital capacity (FVC) and mid-forced expiratory flow (FEF25%–75%), dose–response slope (DRS), exhaled nitric oxide (eNO) and atopic sensitisation between children with recurrent wheeze and those without.SettingPopulation-based, cross-sectional study in Seoul and the Gyeonggi province of Korea conducted as a government-funded programme to perform standardised measurement of the prevalence of allergic diseases, and related factors, in preschool children.Participants900 children aged 4–6 years.Primary and secondary outcome measureseNO, FEV1/FVC, FEF25%–75%, DRS, atopic sensitisation and allergic diseases.MethodsChildren completed the modified International Study of Asthma and Allergies in Childhood questionnaire and underwent eNO assessments, spirometry, methacholine bronchial provocation tests and skin prick tests. Recurrent wheeze was defined as having a lifetime wheeze of more than three episodes, based on the questionnaire. The frequency of hospitalisation and emergency room visits was also obtained by means of the questionnaire. ‘Current’ wheeze was defined as having symptoms or treatments within the past 12 months.ResultsThe prevalence of recurrent wheeze was 13.4%. Children with recurrent wheeze showed a higher prevalence of lifetime or current allergic rhinitis (p=0.01 and p=0.002, respectively) and lifetime atopic dermatitis (p=0.007). Children with recurrent wheeze showed lower FEV1/FVC (p=0.033) and FEF25%–75%(p=0.004), and higher eNO levels (p=0.013) than those without recurrent wheeze. However, the DRS, prevalence of atopic sensitisation and serum IgE levels were not significantly different between the two groups.ConclusionsRecurrent wheeze in preschool children may be associated with airway inflammation and diminished airway function, but not with AHR or atopy.


Author(s):  
Chi ZHANG ◽  
Bangming CAO ◽  
Xingmei HUANG ◽  
Jian GU ◽  
Ming XIA ◽  
...  

Background: The role of serum calcium in coronary artery disease (CAD) patients with or without first incident acute myocardial infarction has not been studied previously. This study aimed to assess the relationship between serum calcium and first incident acute myocardial infarction. Methods: This cross-sectional study was conducted from Jan 2014 to Dec 2016. All the participants were from our database, described in detail elsewhere including 1609 cases and 3252 controls. Multiple logistic regression was carried out to explore the effect of serum calcium on first incident acute myocardial infarction. Interaction between serum calcium and risk factors were evaluated. Results: Patients with first incident acute myocardial infarction have significantly lower serum calcium concentrations than those without acute myocardial infarction (2.18 (0.21) vs 2.24 (0.19) mmol/L, P<0.0001). After adjusting for sex and age, logistic regression showed that serum calcium was significantly associated with first incident acute myocardial infarction (odds ratio (OR): 1.50, 95% confidence interval (CI): 1.41-1.60). Further adjusted for potential confounders, serum calcium was associated with first incident acute myocardial infarction (OR: 1.32, 95% CI: 1.22-1.42). Moreover, the association still existed when patients were divided into subgroups according to gender and age. A significant interaction was found between serum calcium and diabetes mellitus (DM), lipoprotein (a) (Lp (a)), and serum albumin. Conclusion: Serum calcium was associated with first incident acute myocardial infarction among CAD patients in both sexes and in age categories. This study provides further evidence showing the value of serum calcium levels in clinical practice.


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