scholarly journals Metastatic transitional cell carcinoma of the bladder in an ileal conduit stoma. A case report and literature review

2021 ◽  
Vol 81 (2) ◽  
pp. 1-6
Author(s):  
Cayo Augusto Estigarribia-Benitez ◽  
Pablo Oteo-Manjavacas ◽  
Cristina García-Juarranz ◽  
Ines Hernandez-Andres ◽  
Luis Ignacio Fiter-Gomez
Keyword(s):  
Bladder Cancer ◽  
Lymph Nodes ◽  
Urothelial Carcinoma ◽  
Radical Cystectomy ◽  
Urinary Diversion ◽  
Ileal Conduit ◽  
Transitional Cell ◽  
Pathological Examination ◽  
Regional Lymph Nodes ◽  
Diversion Stoma

Clinical case presentation: An 80-year-old man was admitted to our emergency department due to fever and progressively growing mass in the urinary diversion stoma four months after a radical cystectomy for muscle invasive bladder cancer. Surgical resection was done, and histo-pathological examination revealed metastases of high-grade urothelial carcinoma. After almost three years of follow-up any sign of recurrence did not seen. Relevance: Urothelial cancer at all stages can metastasize to other organs. Metastasis occurs hematogenously to all organs, most frequently the lungs, liver, bone, or lymphatically to regional lymph nodes in the pelvis, or further to retroperitoneal lymph nodes. Metastasis of bladder cancer in the ileal conduit stoma is unusual. Cancer recurrence after radical cystectomy has-been reported in ureteroileal anastomosis. Clinical implications: Surgical treatment is an option in these patients. Adjuvant radiotherapy and / or chemotherapy would be possible alternatives in more than one site of metastasis.  There are no clinical guidelines establishing their correct management. Conclusion: The urinary diversion stoma metastases secondary to a urothelial carcinoma is a rare entity. Direct implantation during the surgical act, hematogenous, lymphatic or mixed dissemination, could justify metastatic implantation.  

Impact of perivesical lymph nodes on survival after radical cystectomy.

2014 ◽  
Vol 32 (4_suppl) ◽  
pp. 350-350
Author(s):  
Brian Robin Hu ◽  
Raj Satkunasivam ◽  
Jie Cai ◽  
Gus Miranda ◽  
Siamak Daneshmand
Keyword(s):  
Bladder Cancer ◽  
Lymph Nodes ◽  
Urothelial Carcinoma ◽  
Radical Cystectomy ◽  
Univariate Analysis ◽  
Multivariable Analysis ◽  
Pelvic Lymphadenectomy ◽  
Lymph Node Staging ◽  
Prognostic Impact ◽  
Significant Difference

350 Background: Lymph node staging for bladder cancer is dependent upon both location and number. This study characterizes perivesical (PV) lymph nodes (LN) found at radical cystectomy and evaluates their prognostic impact. Methods: We reviewed our Institutional Review Board-approved database from 1971-2009 including all patients who underwent radical cystectomy with pelvic lymphadenectomy for curative intent for urothelial carcinoma. Clinical and pathologic data were obtained. Patients were analyzed in three groups: PV LN+/other LN-, PV LN+/other LN+, and PV LN-/other LN+. Kaplan-Meier curves were used to estimate recurrence free survival (RFS) and overall survival (OS). Multivariable Cox regression (including pathologic T stage, number of positive LN, highest level of positive LN, chemotherapy, and margin status) was performed to evaluate associations between PV LN status and survival. Results: A total of 2,045 patients underwent radical cystectomy for urothelial carcinoma of which 2011 met inclusion criteria. PV LN were identified in 936 (47%) patients, positive in 197 (10%) patients, and represented isolated LN positive disease in 101 (5%) patients. On univariate analysis, positive PV LN were associated with a higher likelihood of extravesical disease (>pT2) when compared with other positive LN (p=0.023). There was no significant difference in RFS or OS when comparing patients with negative PV LN to those with PV LN not identified. On multivariable analysis, patients with PV LN+/other LN+ had a significantly worse RFS (HR 1.75, 95% CI 1.29-2.38, p<0.001) and OS (HR 1.66, 95% CI 1.27-2.19, p<0.001) when compared with PV LN-/other LN+. There was no significant difference in RFS or OS when comparing patients with PV LN+/other LN- to PV LN-/other LN+. Conclusions: PV LN are identified in a significant portion of patients after radical cystectomy with pelvic lymphadenectomy. Positive PV LN, when in combination with other positive LN, portends worse survival even when correcting for the number of positive LN. No significant difference in survival was seen comparing patients with isolated positive PV LN to those with other positive LN. This study highlights the importance of PV LN in pathologic analysis and bladder cancer staging.

scholarly journals Pathological Profile, Early Complications, Functional and Oncological Outcome after Radical Cystectomy - Ileal Conduit for Bladder Cancer Patients in Sanglah General Hospital between January 2013 and December 2016

2018 ◽  
Vol 6 (9) ◽  
pp. 1647-1651 ◽  
Author(s):  
Yudiana Wayan ◽  
Pratiwi Dinar Ayu ◽  
Oka A. A. Gde ◽  
Niryana Wayan ◽  
I Putu Eka Widyadharma
Keyword(s):  
Bladder Cancer ◽  
Cancer Patients ◽  
Radical Cystectomy ◽  
Urinary Diversion ◽  
Ileal Conduit ◽  
Wound Dehiscence ◽  
Oncological Outcome ◽  
Pathological Result ◽  
Muscle Invasive

BACKGROUND: Radical cystectomy is the standard treatment for nonmetastatic bladder cancer (muscle-invasive and selective superficial bladder cancer). There are many types of urinary diversion after this procedure; the ileal conduit is the most and simplest one. AIM: To asses clinical, pathological profile, early complication, functional and oncological outcome after radical cystectomy and ileal conduit for muscle-invasive bladder cancer patients. METHOD: Between January 2013 and December 2016, there were 68 patients diagnosed with bladder cancer. From those patients, 24 (35.29%) patients had been performed radical cystectomy with ileal conduit type for urinary diversion (100%). Patients demographic, clinical and pathological profile, early postoperative complication, functional and oncological outcome were collected from the medical record. RESULT: Among the 24 patients who underwent radical cystectomy, 20 patients were male (83.3%) with the mean age was 57.3 y.o (33–77 y.o). Twelve patients (50%) showed pT4 and pT2 respectively. Based on pathological result 20 patient (83.34%) had the urothelial carcinoma, three patients (12.5%) had squamous cell carcinoma, and one patient (4.1%) had adenocarcinoma. Two patients (8.3%) got neoadjuvant chemotherapy, and nine patient (37.5%) of patients followed adjuvant chemotherapy after surgery. Wound dehiscence, fistula enterocutan, prolong ileus, leakage anastomosis and sepsis were kind of complication after surgery. One year's survival rate is 84%, mortality rate 20.8% and a recurrence rate of 20.8% in 4 years follow up. CONCLUSION: Radical cystectomy and ileal conduit type of urinary diversion still become the preferable procedure for nonmetastatic bladder cancer with good functional and oncological outcome.

scholarly journals What is the Urinary Diversion of Choice after Cystectomy in 2020?

2020 ◽  
Vol 8 ◽  
Author(s):  
Youssef Kharbach ◽  
Abdelhak Khallouk
Keyword(s):  
Bladder Cancer ◽  
Randomized Trial ◽  
Radical Cystectomy ◽  
Urinary Diversion ◽  
Ileal Conduit ◽  
Underlying Disease ◽  
The State ◽  
Prospective Randomized Trial

Urinary diversion is often indicated after radical cystectomy for bladder cancer. It can either be non-continent or continent. Ileal conduit and orthotopic urinary diversions (neobladder) are by far the most commonly used diversions. The choice of the urinary diversion to be carried out is done on several levels in relation to the underlying disease, the state of the patient and the surgeon preference. It is inappropriate to make direct comparisons between enterocystoplasty and ileal conduit because of the differences in the choice of patients for each technique making a prospective randomized trial unlikely. The choice of the technique must be made after clearly informing and explaining explaining to the patient to enable him accept and adapt to his urinary diversion.

scholarly journals LAPAROSCOPIC RADICAL CYSTECTOMY WITH ILEAL CONDUIT URINARY DIVERSION, FIRST EXPERIENCE IN BANDUNG

2015 ◽  
Vol 22 (2) ◽  
Author(s):  
Davis Roland Gustav Jouwena ◽  
Sawkar Vijay Pramod
Keyword(s):  
Radical Cystectomy ◽  
Urinary Diversion ◽  
Operative Time ◽  
Ileal Conduit ◽  
Transitional Cell ◽  
Radical Cystoprostatectomy ◽  
Small Incision ◽  
Estimated Blood Loss ◽  
Urine Production ◽  
Carcinoma Of The Bladder

Objective: To report our experience in performing laparoscopic radical cystectomy with ileal conduit urinary diversion (extracorporeal reconstruction). Material & method: This study was take place in Hasan Sadikin Hospital Bandung. A 54-year-old male with histologically proven transitional cell carcinoma of the bladder cT2bN0M0 underwent a laparoscopic radical cystoprostatectomy and ileum dissection was performed under laparoscopy. Ileal conduit and stoma reconstruction performed extracorporeal through small incision between ports (about 4cm). Results: The surgical margins were free of disease. The operative time was 360 minutes. Estimated blood loss was 600cc. Hospital stay was 5 days. Patient was discharge with no complication of post-op wound, and urine production about 1500cc/24hrs via stoma. Conclusion: Laparoscopic radical cystectomy with ileal conduit extracorporeal reconstructive urinary diversion could be the preferred means in managing bladder tumor on selective case.

Laparoscopic Radical Cystectomy with Extracorporeal Ileal Conduit Urinary Diversion for Treatment of Chinese Bladder Cancer Patients

2007 ◽  
Vol 79 (3) ◽  
pp. 204-209 ◽  
Author(s):  
Zhen-Li Gao ◽  
Jie Fan ◽  
Jun-Jie Zhao ◽  
Shu-Jie Xia ◽  
Lei Shi ◽  
...  
Keyword(s):  
Bladder Cancer ◽  
Cancer Patients ◽  
Radical Cystectomy ◽  
Urinary Diversion ◽  
Ileal Conduit

scholarly journals Morbidity and Quality of Life in Bladder Cancer Patients following Cystectomy and Urinary Diversion: A Single-Institution Comparison of Ileal Conduit versus Orthotopic Neobladder

ISRN Urology ◽  
2012 ◽  
Vol 2012 ◽  
pp. 1-8 ◽  
Author(s):  
Barbara Erber ◽  
Mark Schrader ◽  
Kurt Miller ◽  
Martin Schostak ◽  
Daniel Baumunk ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Bladder Cancer ◽  
Radical Cystectomy ◽  
Urinary Diversion ◽  
Ileal Conduit ◽  
Oncological Outcome ◽  
University Hospital ◽  
Ileal Neobladder ◽  
Eortc Qlq

Objective. To evaluate and compare noncontinent and continent urinary diversion after radical cystectomy in patients with bladder cancer. Methods. A total of 301 patients submitted to radical cystectomy at the Charité-University Hospital Berlin from 1993 to 2007 including 146 with an ileal conduit and 115 with an ileal neobladder. Clinical and pathological data as well as oncological outcome were retrospectively analyzed and compared. Quality of life was analyzed using the EORTC QLQ-C30 and BLM30 questionnaires. Results. 69.1% and 69.6% of all patients who received an ileal conduit and ileal neobladder, respectively, developed early complications. The two groups differed significantly concerning the occurrence of postoperative ileus (P=0.02) favoring patients who received an ileal conduit but not with regard to any other early-onset complication evaluated. Patients with ileal neobladder had a significantly better global health status and quality of life (P=0.02), better physical functioning (P=0.02), but also a higher rate of diarrhoea (P=0.004). Conclusion. Cystectomy with any type of diversion remains a complication-prone surgery. Even if the patient groups are not homogeneous in all respects, there are many arguments in favor of the ileal neobladder as the urinary diversion of choice.

182: Stomal Complications in Patients Undergoing Radical Cystectomy and Ileal Conduit Urinary Diversion for Bladder Cancer

2007 ◽  
Vol 177 (4S) ◽  
pp. 61-61
Author(s):  
Aaron Lentz ◽  
Matthew Sands ◽  
Erik Kouba ◽  
Eric M. Wallen ◽  
Raj S. Pruthi
Keyword(s):  
Bladder Cancer ◽  
Radical Cystectomy ◽  
Urinary Diversion ◽  
Ileal Conduit ◽  
Stomal Complications

scholarly journals Quality of life assessment in patients of bladder cancer with radical cystectomy and ileal conduit

2019 ◽  
Vol 6 (11) ◽  
pp. 4012
Author(s):  
Vikas Gupta ◽  
Vardachary Srinivas
Keyword(s):  
Quality Of Life ◽  
Bladder Cancer ◽  
Radical Cystectomy ◽  
Urinary Diversion ◽  
Ileal Conduit ◽  
Cancer Control ◽  
Well Being ◽  
Life Assessment ◽  
Outcome Index

Background: Bladder cancer, a lethal disease accounts for 3% of cancer deaths. With possibility of various urinary diversion options after bladder removal having comparable cancer control and complications, quality of life becomes an important factor in deciding the type of urinary diversion.Methods: Retrospective observational study with statistically appropriate sample size of 50. Patients of radical cystectomy and ileal conduit given validated Functional Assessment Of Chronic Illness Therapy for Bladder Cancer ( FACT-Bl ) Questionnaire to answer about post-operative quality of life in terms of five parameters i.e., physical, mental, social, emotional and cancer specific well-being after 1 year of surgery.Results: Results analysed by FACIT-Bl questionnaire analysis methods statistically, in terms of total scores and sub-scores. In our study the mean scores of physical well-being (PWB) subscale is 24.08±4.67 (range o-28), social well-being (SWB) subscale is 23.52±4.35 (range 0-28) , emotional well-being (EWB) subscale is 20.06±5.09, functional well-being (FWB) subscale is 21.84±6.01 (range 0-28), bladder cancer subscale is 36.44±5.72 (range 0-48). While mean trial outcome index score is 82.16±3.5 (range 0-104), FACT- General (G) score is 89.50+ 15.88 and mean FACT-Bl total score is 125.94±19.04.These scores provides the quantitative assessment of the quality of life and higher scores indicates better quality of life.Conclusions: Assessing quality of life for a particular type of urinary diversion, with questionnaires, gives surgeons and patients, guidance regarding diversion of choice.

Sign in / Sign up

Export Citation Format

Share Document