scholarly journals Drying kinetics of cellulose nanofibers suspensions

2018 ◽  
Author(s):  
Belal Al Zaitone
Keyword(s):  
Process Development ◽  
Cellulose Nanofibers ◽  
Particle Morphology ◽  
Biological Properties ◽  
Drying Kinetics ◽  
Acoustic Levitation ◽  
Drying Process ◽  
Single Droplet ◽  
Air Temperatures ◽  
Droplet Drying

Cellulose nanofibers (CNF) is used in various pharmaceutical applications due to its unique characteristics i.e., biodegradability, mechanical and biological properties. CNF is often produced by spray drying process, knowledge of the drying kinetics in terms of mass and heat transfer on the scale of single droplet is important for process development and model validation. Acoustic levitator was used to study drying process of CNF suspension at different air temperatures and initial CNF concentrations. The unique property of acoustic levitation to hold single droplet contactless in the air, enables to study particle morphology during drying process, calculate evaporation rate and estimate particle porosity. Results show that packed particles result at lower initial concentration and temperature has a moderate influence on mean porosity of CNF dried particles. Keywords: acoustic levitation; droplet; drying kinetics; Cellulose Nanofibers 

scholarly journals Unraveling Particle Formation: From Single Droplet Drying to Spray Drying and Electrospraying

Pharmaceutics ◽  
2020 ◽  
Vol 12 (7) ◽  
pp. 625 ◽  
Author(s):  
Eline Boel ◽  
Robin Koekoekx ◽  
Sien Dedroog ◽  
Iurii Babkin ◽  
Maria Rosaria Vetrano ◽  
...  
Keyword(s):  
Spray Drying ◽  
Formation Process ◽  
Process Development ◽  
Particle Morphology ◽  
Cost Effective ◽  
Particle Formation ◽  
Particle Engineering ◽  
Single Droplet ◽  
Comprehensive Overview ◽  
Droplet Drying

Spray drying and electrospraying are well-established drying processes that already have proven their value in the pharmaceutical field. However, there is currently still a lack of knowledge on the fundamentals of the particle formation process, thereby hampering fast and cost-effective particle engineering. To get a better understanding of how functional particles are formed with respect to process and formulation parameters, it is indispensable to offer a comprehensive overview of critical aspects of the droplet drying and particle formation process. This review therefore closely relates single droplet drying to pharmaceutical applications. Although excellent reviews exist of the different aspects, there is, to the best of our knowledge, no single review that describes all steps that one should consider when trying to engineer a certain type of particle morphology. The findings presented in this article have strengthened the predictive value of single droplet drying for pharmaceutical drying applications like spray drying and electrospraying. Continuous follow-up of the particle formation process in single droplet drying experiments hence allows optimization of manufacturing processes and particle engineering approaches and acceleration of process development.

Drying kinetics and particle formation of potato powder during spray drying probed by microrheology and single droplet drying

2019 ◽  
Vol 116 ◽  
pp. 483-491 ◽  
Author(s):  
Yaoyao Tan ◽  
Yue Zhao ◽  
Honghai Hu ◽  
Nan Fu ◽  
Chunjiang Zhang ◽  
...  
Keyword(s):  
Spray Drying ◽  
Particle Formation ◽  
Drying Kinetics ◽  
Single Droplet ◽  
Potato Powder ◽  
Droplet Drying

Theoretical Models of Single Droplet Drying Kinetics: A Review

2010 ◽  
Vol 28 (2) ◽  
pp. 278-293 ◽  
Author(s):  
M. Mezhericher ◽  
A. Levy ◽  
I. Borde
Keyword(s):  
Theoretical Models ◽  
Drying Kinetics ◽  
Single Droplet ◽  
Droplet Drying

scholarly journals Influence of Commercial Protease and Drying Process on Antioxidant and Physicochemical Properties of Chicken Breast Protein Hydrolysates

Foods ◽  
2021 ◽  
Vol 10 (12) ◽  
pp. 2994
Author(s):  
Phatthawin Setthaya ◽  
Sanchai Jaturasitha ◽  
Sunantha Ketnawa ◽  
Thanongsak Chaiyaso ◽  
Kenji Sato ◽  
...  
Keyword(s):  
Physicochemical Properties ◽  
Antioxidant Activities ◽  
Particle Morphology ◽  
Biological Properties ◽  
Enzyme Treatment ◽  
Color Measurement ◽  
Chicken Breast ◽  
Degree Of Hydrolysis ◽  
Drying Process ◽  
Treatment Conditions

Different proteases can be applied to produce certain bioactive peptides. This study focused on the effects of some commercial proteases and drying processes on the physical, chemical, and biological properties of chicken breast hydrolysates (CBH). Chicken breast hydrolyzed with Alcalase® presented a higher degree of hydrolysis (DH) than papain. Moreover, the treatment with Alcalase®, followed by papain (A-P), was more proficient in producing antioxidant activities than a single enzyme treatment. Conditions comprising 0.63% Alcalase® (w/w) at pH 8.0 and 52.5 °C for 3 h, followed by 0.13% papain (w/w) at pH 6.0 and 37 °C for 3 h, resulted in the highest yields of DH and peptide contents. The spray-dried microencapsulated powder improved the physicochemical properties including moisture content, color measurement, solubility, and particle morphology. In summary, the dual enzyme application involving the hydrolysis of Alcalase® and papain, coupled with the spray-drying process, could be used to produced antioxidant CBH.

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