scholarly journals Ultrasound Evaluation of Visceral Fat Thickness for Prediction of Metabolic Syndrome in the First Trimester of Pregnancy in a Sample of Non-obese Iranian Women

2019 ◽  
Vol 34 (4) ◽  
pp. 308-312
Author(s):  
Firoozeh Ahmadi ◽  
Somayeh Moukhah ◽  
Roya Hosseini ◽  
Amirhossein Maghari
Keyword(s):  
Metabolic Syndrome ◽  
Visceral Fat ◽  
First Trimester ◽  
Iranian Women ◽  
Ultrasound Evaluation ◽  
First Trimester Of Pregnancy ◽  
Fat Thickness

Ultrasonographic visceral fat thickness in the first trimester can predict metabolic syndrome and gestational diabetes mellitus

Endocrine ◽  
2014 ◽  
Vol 47 (2) ◽  
pp. 478-484 ◽  
Author(s):  
Esra Bahar Gur ◽  
Ozlem Ince ◽  
Guluzar Arzu Turan ◽  
Muammer Karadeniz ◽  
Sumeyra Tatar ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Metabolic Syndrome ◽  
Gestational Diabetes ◽  
Gestational Diabetes Mellitus ◽  
Visceral Fat ◽  
First Trimester ◽  
Fat Thickness

Gestational metabolic syndrome and neonatal anthropometric indices: a prospective cohort study

2021 ◽  
Vol 29 (7) ◽  
pp. 386-391
Author(s):  
Zeinab Hatamian ◽  
Lida Moghaddam-Banaem ◽  
Samira Mokhlesi ◽  
Marzieh Saei Ghare Naz
Keyword(s):  
Metabolic Syndrome ◽  
Cohort Study ◽  
Birth Weight ◽  
Prospective Cohort Study ◽  
Prospective Cohort ◽  
Linear Regression Analysis ◽  
First Trimester ◽  
P Value ◽  
Anthropometric Parameters ◽  
First Trimester Of Pregnancy

Background and aim There is limited knowledge about the effect of maternal metabolic syndrome (MetS) on the anthropometric parameters of newborns. Therefore, the authors aimed to evaluate the association between MetS in the first trimester of pregnancy with weight and height of the newborn. Methods This prospective cohort study was conducted on 455 pregnant women in Tehran during their first trimester of pregnancy. MetS was defined as the coexistence of three or more of the following criteria: fasting blood sugar (FBS) level ≥92 mg/dl, blood pressure ≥130.85 mm/hg, triglyceride ≥150 mg/dl, high density lipoprotein ≤50 mg/dl, and body mass index (BMI) ≥30 kg/m2. All participants were followed up to childbirth. After birth, the baby's weight and height data were collected from the birth certificate. Results Linear regression analysis showed FBS (ß: 0.100, p-value: 0.038), BMI (ß: 0.139, p-value: 0.004), and MetS (ß: -0.122, p-value: 0.015) were significantly associated with birth weight but no statistically significant results were found for birth height. Conclusion MetS and some of its components in pregnancy can affect birth weight of neonates.

scholarly journals THICKNESS OF subcutaneous AND preperitoneal fat: ASSESSMENT AND IMPORTANCE OF THE PARAMETER IN PREGNANT WOMEN WITH COMPONENTS OF METABOLIC SYNDROME

2018 ◽  
pp. 39-43
Author(s):  
O. N. Kononova ◽  
A. M. Pristrom ◽  
N. V. Nikolayeva ◽  
O. V. Zotova ◽  
A. V. Korotayev ◽  
...  
Keyword(s):  
Metabolic Syndrome ◽  
Pregnant Women ◽  
Metabolic Disorders ◽  
Risk Group ◽  
First Trimester ◽  
Reproductive Age ◽  
Cardiovascular Risks ◽  
Lipid Exchange ◽  
Reproductive Losses ◽  
First Trimester Of Pregnancy

Objective: to assess results of ultrasonography of the thickness of subcutaneous and preperitoneal fat in women with components of metabolic syndrome in the first trimester of pregnancy (n = 143). Material and methods. Anthropometrical parameters, indicators of carbohydrate and lipid exchange have been investigated. The thickness of subcutaneous and preperitoneal fat has been studied. Results. It has been found that increased thickness of subcutaneous and preperitoneal fat is observed in pregnant women with both metabolic syndrome and risk factors for development of metabolic syndrome. Women of reproductive age with obesity make a risk group of development of metabolic disorders in the gestational period. Conclusion. To prevent metabolic disorders and reproductive losses, it is necessary to take measures to reduce overweight in women before pregnancy. Prevalence and importance of obesity and metabolic syndrome in female patients of reproductive age necessitate further comprehensive and thorough investigation of pathogenetic mechanisms of its development aimed at decrease of cardiovascular risks in future.

scholarly journals Components of metabolic syndrome in the first trimester of pregnancy as predictors of adverse perinatal outcome

2016 ◽  
Vol 87 (9) ◽  
pp. 644-650 ◽  
Author(s):  
Michał Migda ◽  
Marian S. Migda ◽  
Bartosz Migda ◽  
Patrycja Krzyżanowska ◽  
Ewa Wender-Ożegowska
Keyword(s):  
Metabolic Syndrome ◽  
Perinatal Outcome ◽  
First Trimester ◽  
Adverse Perinatal Outcome ◽  
First Trimester Of Pregnancy

scholarly journals Assessment of β-human-derived chorionic gonadotrophic hormone (βhCG) and pregnancy-associated plasma protein A (PAPP-A) levels as predictive factors of preeclampsia in the first trimester among Iranian women: a cohort study

2019 ◽  
Vol 19 (1) ◽  
Author(s):  
Maryam Honarjoo ◽  
Shahnaz Kohan ◽  
Elahe Zarean ◽  
Mohammad Javad Tarrahi
Keyword(s):  
Cohort Study ◽  
Plasma Protein ◽  
Predictive Factors ◽  
Protein A ◽  
First Trimester ◽  
Health Centers ◽  
Screening Tests ◽  
Iranian Women ◽  
First Trimester Of Pregnancy ◽  
Low Levels

Abstract Background Preeclampsia (PE) is a leading cause of maternal and perinatal mortality. There are controversial findings regarding the prediction of PE through the assessment of the Pregnancy-Associated Plasma Protein A (PAPP-A) and β-Human-Derived Chorionic Gonadotrophic hormone (βhCG) levels in the first trimester of pregnancy. Therefore, this cohort study was conducted to evaluate of PAPP-A and βhCG levels as predictive factors for PE development in the first trimester among Iranian women. Methods In this cohort study, a total of 4605 volunteer Primigravida and Multigravida women were selected by the census from 16 randomly selected Health Centers in Isfahan, Iran, from July 2016 to June 2018. Eligible pregnant women participated in the study had already undergone fetal anomalies screening tests between 11 + 0 and 13 + 6 weeks of pregnancy and their PAPP-A and βhCG biomarkers were adjusted to the Multiples of the Median (MOM). MOM PAPP-A <  0.4 and MOM βhCG > 3 were considered abnormal. The samples were followed up until delivery. The biomarkers’ levels were compared in the two groups of women with and without PE and Relative risk (RR) and odds ratio (OR) of PE calculated. Results In the PE group, the mean MOM PAPP-A was significantly lower (1 vs. 1.09 with P = 0.006) and MOM βhCG was significantly higher (1.51 vs. 1.14 with P = 0.001) than the group without PE. RR and OR for PE in subjects with MOM PAPP-A <  0.4 were reported as follows: RR = 2.49, (p = 0.001) and OR = 2.09, (p = 0.001). RR and OR for PE in subjects with MOM βhCG > 3 were also reported as follows: RR = 4.02, (p = 0.001) and OR = 5.65, (p = 0.001). Adjusted OR for MOM PAPP-A <  0.4 and MOM βhCG > 3 was obtained as follows: OR = 2.09 (P = 0.001) and OR = 5.65 (P = 0.001), respectively. Conclusion The results of the study showed that the high levels of βhCG would cause 5.65 times increase and the low levels of PAPP-A would cause 2.09 times increase in the chance of developing PE.

scholarly journals Potential Role of New Anthropometric Parameters in Childhood Obesity with or Without Metabolic Syndrome

2019 ◽  
Vol 7 (23) ◽  
pp. 3930-3936 ◽  
Author(s):  
Nagwa Abdallah Ismail ◽  
Shadia H. Ragab ◽  
Abeer M. Nour E lDin Abd ElBaky ◽  
Mona Hamid Ibrahim
Keyword(s):  
Metabolic Syndrome ◽  
Visceral Fat ◽  
Subcutaneous Fat ◽  
Shape Index ◽  
Visceral Adiposity Index ◽  
Obese Children ◽  
Anthropometric Parameters ◽  
Liver Size ◽  
Subcutaneous Fat Thickness ◽  
Fat Thickness

BACKGROUND: Obese children and adolescents are more prone to have metabolic syndrome (MS).MS is a cluster of cardiovascular risk factors associated with insulin resistance. Body round index [BRI], visceral adiposity index [VAI] and a body shape index [ABSI] are among the new obesity anthropometric parameters. AIM: To evaluate the new markers for obesity in children and their possible association with other laboratory and clinical variables of MS. METHODS: Eighty nine obese children and 40 controls aged 10-18 years were recruited. Full history taking, thorough clinical examination, anthropometric and biochemical features were performed in the studied groups. Subcutaneous fat thickness (SFT) and visceral fat thickness (VFT) were estimated by ultrasonography. RESULTS: Obese children, exhibited significantly higher values in all anthropometric measurements (P < 0.001). Diastolic and systolic blood pressure were significantly higher (P < 0.001) in the obese group. ABSI, BRI and VAI have been found to be significantly higher in obese subjects (P < 0.001), with no significant gender difference. BMI, WHtR, WC/HR, SBP, DBP, subcutaneous fat thickness and visceral fat thickness, Liver Span, ABSI, BRI, VAI and HOMA_IR were significantly higher among children with MS than those without MS. Positive significant correlations of VAI with BMI, WC/Ht, WC/Hip, SBP, DBP, SFT, VFT, Liver size and HOMA-IR (r = 0.384, 0.239, 0.268, 0.329, 0.516, 0.320, 0.254, 0.251, and 0.278 respectively) are shown. The area under the ROC curve (AUC) of BMI, VAI, ABSI, BRI for predicting MS was 0.802 (0.701-0.902), 0.737 (0.33-0.841), 0.737 (0.620-0.855), 0.816 (0.698-0.934). CONCLUSION: We suggest using the VAI and WHtR indexes, as they are better predictor of MS.

scholarly journals Sonographic Measurement of Visceral Fat Thickness as a Correlate of Existing Metabolic Syndrome- A Cross-sectional Study

2021 ◽  
Author(s):  
Deep Yadav ◽  
Akhilesh Rao ◽  
Aneesh Mohimen ◽  
Yayati Pimpalwar
Keyword(s):  
Metabolic Syndrome ◽  
Visceral Fat ◽  
Predictive Value ◽  
Low Cost ◽  
Cross Sectional Study ◽  
Mean Value ◽  
Study Cohort ◽  
Sectional Study ◽  
Cross Sectional ◽  
Fat Thickness

Introduction: Metabolic syndrome is a well-known disease of multiple risk factors that has at its core, insulin resistance accompanying abnormal adipose deposition and function. Multiple studies demonstrate a potential relationship between Visceral Fat Thickness (VFT) and metabolic syndrome. Ultrasound provides a radiation free low-cost alternative, which is high reproducible in the quantification of visceral fat and can act as an effective screening modality. The simplicity of the method combined with its objectiveness makes it advantageous for accurate measurement of VFT. Aim: To correlate of sonographic measurement of VFT with existing metabolic syndrome. Materials and Methods: This cross-sectional study was conducted on all patients that underwent ultrasound at the study center between August 2016 to August 2019 and were clinically suspected of suffering from metabolic syndrome at the Endocrinology Outpatient Department (OPD). Collation of data into three categories based on VFT (<7 cm, 7 to 10 cm and >10 cm) was done. The patients in each category underwent further testing and metabolic syndrome was either ruled out or diagnosed. Results: The study cohort comprised of 2022 patients. The VFT ranged between 4 and 16 with a mean value of 10.8 and standard deviation of 2.8. The percentage of patients with metabolic syndrome increased in proportion to the increased VFT. VFT >10 cm was found to have specificity and Positive Predictive Value (PPV) 92.52% and 92.53% respectively while VFT <7 cm was found to have a sensitivity and Negative Predictive Value (NPV) of 95.11% and 95.10%, respectively. Conclusion: Ultrasound seems to be the best screening tool for the assessment of intra-abdominal fat deposition as the number of VFT subjects with metabolic syndrome in Category 1 was higher.

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