scholarly journals Comparison of Anterior Chamber Parameters between Normal and Keratoconus Eyes using Scheimpflug Photography

2016 ◽  
Vol 5 (3) ◽  
pp. 105-108
Author(s):  
Nagla Hassan Ali ◽  
Mohammed Othman AbdElKhalek ◽  
Hanan Elghoneimy
Keyword(s):  
Anterior Chamber ◽  
Corneal Thickness ◽  
Anterior Chamber Depth ◽  
Progressive Increase ◽  
Control Group ◽  
Ophthalmological Examination ◽  
Scheimpflug Photography ◽  
Scheimpflug Camera ◽  
Chamber Volume ◽  
Group I

ABSTRACT Aim To evaluate anterior chamber indices including anterior chamber depth (ACD) and anterior chamber volume (ACV) with the progression of keratoconus using a rotating Scheimpflug camera to determine the sensitivity and specificity of these parameters in discriminating keratoconus from normal eyes. Materials and methods After full ophthalmological examination in the Memorial Institute of Ophthalmic Research, the patients are divided into two groups: Group I consisting of 50 eyes of normal control. Group II consists of 50 eyes of moderate keratoconus. All the subjects were evaluated with a Pentacam Scheimpflug camera (Oculus, Wetzlar, Germany). Keratoconic eyes were evaluated by vertical asymmetry (VI), keratoconus index (KI), thinnest corneal thickness (TCT) with front elevation at thinnest location (F.Ele.Th) and back elevation at thinnest location (B.Ele.Th) and then divided into three groups according to mean keratometer (K) readings: Mild (K = less than 47.0 D), moderate (K = 47.0 to 52.0 D), and severe (K = 52.0 D or higher), and ACD and ACV were obtained after exclusion of mild and severe cases. Results With the progression of the disease, there was statistically significant differences in ACD and ACV measurements between the normal and moderate keratoconus eyes with progressive increase in the ACD and ACV with disease progression. Conclusion Anterior chamber parameters including depth and volume showed significant increase with moderate keratoconus than control. How to cite this article Ali NH, AbdElKhalek MO, El Ghonemy HM. Comparison of Anterior Chamber Parameters between Normal and Keratoconus Eyes using Scheimpflug Photography. Int J Kerat Ect Cor Dis 2016;5(3):105-108.

scholarly journals Evaluation of Anterior Segment’s Structures in Tilted Disc Syndrome

2016 ◽  
Vol 2016 ◽  
pp. 1-4 ◽  
Author(s):  
Ercan Ozsoy ◽  
Abuzer Gunduz ◽  
Ersin Ersan Demirel ◽  
Tongabay Cumurcu
Keyword(s):  
Anterior Chamber ◽  
Axial Length ◽  
Corneal Thickness ◽  
Anterior Segment ◽  
Anterior Chamber Depth ◽  
Control Group ◽  
Tilted Disc Syndrome ◽  
Chamber Volume ◽  
Significant Difference ◽  
Tilted Disc

Purpose. To evaluate anterior segment’s structures by Pentacam in patients with tilted disc syndrome (TDS).Methods. Group 1 included forty-six eyes of forty-six patients who have the TDS. Group 2 including forty-six eyes of forty-six cases was the control group which was equal to the study group in age, gender, and refraction. A complete ophthalmic examination was performed in both groups. All cases were evaluated by Pentacam. The axial length (AL) of eyes was measured by ultrasound. Quantitative data obtained from these measurements were compared between two groups.Results. There was no statistically significant difference for age, gender, axial length, and spherical equivalent measurements between two groups (p=0.625,p=0.830,p=0.234, andp=0.850). There was a statistically significant difference for central corneal thickness (CCT), corneal volume (CV), anterior chamber angle (ACA), and pupil size measurements between two groups (p=0.001,p=0.0001,p=0.003, andp=0.001). Also, there was no statistically significant difference for anterior chamber depth (ACD), anterior chamber volume (ACV), and lens thickness (LT) measurements between two groups (p=0.130,p=0.910, andp=0.057).Conclusion. We determined that CCT was thinner, CV was less, and ACA was narrower in patients with TDS. There are some changes in the anterior segment of the eyes with tilted disc.

Is keratoconus associated to thyroid diseases? Assessment of the corneal parameters in patients with congenital hypothyroidism

2021 ◽  
pp. 112067212110399
Author(s):  
Anna M Roszkowska ◽  
Federica Alessandrello ◽  
Małgorzata Waśniewska ◽  
Angelo Tropeano ◽  
Romina Gargano ◽  
...  
Keyword(s):  
Anterior Chamber ◽  
Congenital Hypothyroidism ◽  
Corneal Thickness ◽  
Anterior Chamber Depth ◽  
Nonparametric Test ◽  
Control Group ◽  
P Value ◽  
Postnatal Life ◽  
Chamber Volume ◽  
Significant Difference

Purpose: To investigate the association between keratoconus and congenital hypothyroidism (CH). Patients and methods: Patients were enrolled in this study and divided into two groups. The first group comprised 31 subjects (11M:20F) with the mean age of 15.2 ± 3.9 years. affected by CH, and the control group was composed by 19 healthy individuals (8M:11F) aged 14.3 ± 4.6 years. All patients underwent complete ophthalmologic examination with visual acuity assessment, refraction, slit lamp examination, and retinoscopy. Corneal parameters were measured using Scheimpflug camera (Pentacam® Oculus, Germany). The main outcome measures considered for evaluation were: average corneal curvature (K), central corneal thickness (CCT), anterior elevation and posterior elevation at the thinnest point, corneal volume (CV), anterior chamber depth (ACD), and anterior chamber volume (ACV). Additionally, data from Belin/Ambrosio Enhanced Ectasia Display (BAD) and the high order aberrations were evaluated. Kolmogorov-Smirnov test was used to verify the Gaussian distribution, the comparison between the controls and cases group was performed by Mann-Whitney nonparametric test. A p value less than 0.05 was considered to be statistically significant. The odds ratio was performed in order to quantify the relationship between the congenital hypothyroidism and abnormal values displayed on front BAD. Results: The significant difference in the refractive status between both groups was observed. As to examined corneal and anterior chamber parameters no statistical differences were detected. Conclusions: Congenital hypothyroidism diagnosed and treated since the early postnatal life doesn’t induce abnormalities of corneal parameters suggestive for keratoconus.

scholarly journals Quantifying Contact Lens-Related Changes in Keratoconic Corneal Topographic Indices: An Updated Pentacam Scheimpflug Imaging Analysis

2021 ◽  
Author(s):  
Murat Kaşıkçı ◽  
Aylin Karalezli ◽  
ÖZGÜR EROĞUL ◽  
Hamidu Hamisi Gobeka
Keyword(s):  
Anterior Chamber ◽  
Contact Lens ◽  
Corneal Thickness ◽  
Anterior Chamber Depth ◽  
Control Group ◽  
Imaging Device ◽  
Chamber Volume ◽  
Scheimpflug Imaging ◽  
Group 2 ◽  
Group 1

Abstract PurposeSlowing ectasia progression is critical for maintaining visual potential in keratoconus (KC), for which various therapeutic approaches have been implemented. We used a Pentacam Scheimpflug imaging device to quantify contact lens (CL)-related changes in keratoconic corneal topographic indices.MethodsThirty KC patients (group 1; 60 eyes) were using one of the three CL (rigid gas-permeable CL (RGPCL)-10; hybrid CL (HCL)-10; and scleral CL (SCL)-10 patients). A control group included 30 KC patients (group 2; 60 eyes) not using CLs due to intolerance or inappropriateness. The Pentacam® HR Scheimpflug imaging device was used to measure topographical indices such as Km anterior, Km posterior, K max, corneal thickness (CT; corneal central, apex, and thinnest), corneal volume (CV), anterior chamber volume (ACV), and anterior chamber depth (ACD) at baseline, 3rd, 6th, and 12th months.ResultsMean ages for groups 1 and 2 were 32 ± 10 and 31 ± 90 years, respectively. Group 1 had lower but statistically significant change in K max than group 2 (p < 0.038). Also, group 1 had a minor but non-significant decrease in anterior and posterior keratometry values compared to group 2 (pKm ant. right/left eye = 0.063/0.065 and 0.087/0.094, respectively). RGPCL users had significant changes in central CT, thinnest CT and ACD (p < 0.041). SCL users had more stable changes than other CLs for the thinnest CT along with significant changes in K max, pachy apex and ACV (p < 0.036). HCL users had significantly higher K max stability (p < 0.039).ConclusionRegular use of appropriate therapeutic CLs may help to stabilize corneal deformity, thereby slowing changes in corneal topographic indices in KC.

Laser Peripheral Iridotomy Changes Anterior Chamber Architecture

2016 ◽  
Vol 27 (1) ◽  
pp. 49-54 ◽  
Author(s):  
Christian Theinert ◽  
Peter Wiedemann ◽  
Jan D. Unterlauft
Keyword(s):  
Anterior Chamber ◽  
Corneal Thickness ◽  
Anterior Chamber Depth ◽  
Angle Closure ◽  
Control Group ◽  
Threshold Values ◽  
Characteristic Analysis ◽  
Laser Peripheral Iridotomy ◽  
Peripheral Iridotomy ◽  
Healthy Eyes

Purpose The pressure gradient between anterior and posterior chamber in acute angle closure (AAC) and primary angle closure suspects is balanced by a sufficient laser peripheral iridotomy (LPI). The anterior chamber changes induced by LPI in patients with unilateral AAC were examined and compared to healthy eyes to define threshold values, which may help to discriminate between healthy and diseased eyes. Methods Using Scheimpflug photography, anterior chamber depth (ACD), anterior chamber volume (ACV), anterior chamber angle (ACA), and central corneal thickness (CCT) were measured before and after LPI in both eyes of unilateral AAC cases. These measurements were compared to a group of healthy control eyes to determine threshold values for ACD, ACV, and ACA. Results The ACD, ACV, and ACA increased significantly in the 25 AAC eyes after LPI. The ACD, ACV, ACA, and CCT values in the AAC eyes obtained before LPI were compared to a control group of 59 healthy eyes with wide open chamber angles. The cutoff values revealed by receiver operating characteristic analysis were 2.1 mm for ACD, 90.5 mm2 for ACV, and 27.25° for ACA. Conclusions Our results confirm the significant changes of the anterior segments architecture induced by LPI in AAC eyes. The found threshold values for ACD, ACV, and ACA may help in daily clinical routine to discriminate between healthy eyes and those in need for a prophylactic LPI.

scholarly journals Steeper Iris Conicity Is Related to a Shallower Anterior Chamber: The Gutenberg Health Study

2017 ◽  
Vol 2017 ◽  
pp. 1-10
Author(s):  
Alexander K. Schuster ◽  
Norbert Pfeiffer ◽  
Stefan Nickels ◽  
Andreas Schulz ◽  
Philipp S. Wild ◽  
...  
Keyword(s):  
Anterior Chamber ◽  
Corneal Thickness ◽  
Multivariable Analysis ◽  
Anterior Chamber Depth ◽  
Health Study ◽  
Angle Closure ◽  
Human Lens ◽  
Ophthalmological Examination ◽  
Cross Sectional ◽  
Phakic Eyes

Purpose. To report the distribution of iris conicity (steepness of the iris cone), investigate associated factors, and test whether pseudophakia allows the iris to sink back. Methods. A population-based cross-sectional study was carried out. Ophthalmological examination including objective refraction, biometry, noncontact tonometry, and Scheimpflug imaging (Pentacam®, Oculus) was performed including automated measurement of iris conicity. 3708 phakic subjects, 144 subjects with bilateral and 39 subjects with unilateral pseudophakia were included. Multivariable analyses were carried out to determine independently associated systemic and ocular factors for iris conicity in phakic eyes. Results. Mean iris conicity was 8.28° ± 3.29° (right eyes). Statistical analysis revealed associations between steeper iris conicity and shallower anterior chamber depth, thicker human lens and higher corneal power in multivariable analysis, while older age was related to a flatter iris conicity. Refraction, axial length, central corneal thickness, pupil diameter, and intraocular pressure were not associated with iris conicity. Pseudophakia resulted in a 5.82° flatter iris conicity than in the fellow phakic eyes. Conclusions. Associations indicate a correlation between iris conicity with risk factors for angle-closure, namely, shallower anterior chamber depth and thicker human lens. In pseudophakic eyes, iris conicity is significantly lower, indicating that cataract surgery flattens the iris.

scholarly journals The Effects of Ramadan Fasting on Anterior Segment Parameters, Visual Acuity and Intraocular Pressures of the Eye

2017 ◽  
Vol 11 (1) ◽  
pp. 152-155 ◽  
Author(s):  
Ozlem Barut Selver ◽  
Melis Palamar ◽  
Kevser Gerceker ◽  
Sait Egrilmez ◽  
Ayse Yagci
Keyword(s):  
Visual Acuity ◽  
Anterior Chamber ◽  
Corneal Thickness ◽  
Anterior Segment ◽  
Anterior Chamber Depth ◽  
Ophthalmological Examination ◽  
Significant Difference ◽  
Before And After ◽  
Group 2 ◽  
Group 1

Objective: It is aimed to determine whether fasting during Ramadan has any significant effect on anterior chamber parameters, visual acuity and intraocular pressures. Methods: 31 fasting (Group 1) and 30 non-fasting healthy volunteers (Group 2) were enrolled. All cases underwent an ophthalmological examination and anterior segment parameter evaluation (central corneal thickness (CCT), anterior chamber depth (ACD), anterior chamber volume (ACV), anterior chamber angle (ACA), pupil size) with Pentacam before and after the breaking of the Ramadan fast in Group 1, before and after dinner in Group 2. Results: The mean age was 43.35 ± 13.20 in Group 1, 43.17 ± 12.90 in Group 2 (p= 0.955). No significant difference was detected in any of the parameters in both groups. Conclusion: There is a need for more detailed and associated studies to understand better about the influence of Ramadan fast on various ocular parameters.

scholarly journals Comparing biometry in normal eyes of children with unilateral cataract/corneal disease to age-matched controls

2016 ◽  
Vol 7 (2) ◽  
pp. 108-116
Author(s):  
Adem Gul ◽  
Adnan Cinal ◽  
Cagatay Caglar ◽  
Tekin Yasar ◽  
Adil Kilic
Keyword(s):  
Anterior Chamber ◽  
Axial Length ◽  
Central Corneal Thickness ◽  
Pediatric Patients ◽  
Corneal Thickness ◽  
Anterior Chamber Depth ◽  
Control Group ◽  
Study Group ◽  
Lens Thickness ◽  
The Difference

Objective: To compare ocular biometry and central corneal thickness of unaffected healthy eyes of pediatric patients with monocular cataracts/corneal opacities and age- matched controls.Materials and methods: We studied 329 eyes of 329 children who were between 1 and 12 years old. The study group (n: 164) consisted of healthy fellow eyes of children operated for unilateral congenital/traumatic cataract and corneal laceration. Axial length, anterior chamber depth, lens thickness, vitreous chamber depth, and central corneal thickness were measured by ultrasound biometry/ pachymetry. Results: Axial length was 22.16 mm in the study group and 21.99 mm in the control group. Anterior chamber depth, lens thickness, and vitreous chamber depth results were 3.35; 3.64 and 15.20 in the treatment group and 3.20; 3.63, and 15.15 mm in the control group, respectively. The axial length and all the components, i.e. anterior chamber depth, lens thickness, and vitreous chamber depth are higher in the unaffected healthy eyes of the pediatric patients than that of the control group but only the difference in the anterior chamber depth was statistically significant. The central corneal thickness was 548 microns and 559 microns in the study and the control groups, respectively, and the difference was found to be significant. Conclusion: Greater anterior chamber depth was chiefly responsible for the overall increase in the axial length in the study group. The central corneal thickness was significantly thinner in the study group than that of the control group. 

scholarly journals Predictive factors of the accelerated transepithelial corneal cross-linking outcomes in keratoconus

2022 ◽  
Vol 22 (1) ◽  
Author(s):  
Mi Tian ◽  
Weijun Jian ◽  
Xiaoyu Zhang ◽  
Ling Sun ◽  
Yang Shen ◽  
...  
Keyword(s):  
Anterior Chamber ◽  
Central Corneal Thickness ◽  
Corneal Thickness ◽  
Anterior Chamber Depth ◽  
Cross Linking ◽  
Radius Of Curvature ◽  
Chamber Volume ◽  
Anterior Chamber Volume ◽  
Time Point

Abstract Background This study aimed to evaluate the clinical outcomes and assess preoperative characteristics that may predict outcomes in keratoconus 1 year after accelerated transepithelial corneal cross-linking (ATE-CXL). Methods This prospective study included 93 eyes of 84 consecutive keratoconus patients with 1-year follow-up after ATE-CXL. Preoperative characteristics included corneal astigmatism, anterior chamber depth, anterior chamber volume, radius of curvature, posterior elevation, central corneal thickness (CCT), thinnest corneal thickness, steepest meridian keratometry, flattest meridian keratometry, and the maximum keratometry (Kmax). Data were obtained preoperatively and at 1, 3, 6, and 12 months postoperatively. The patient eyes were grouped into 3 subgroups according to CCT and Kmax values to observe the changes of keratoconus progression. Results All patients were successfully operated without complications at any follow-up time point. Mean changes of Kmax from baseline at 6 and 12 months were − 0.60 ± 2.21 D (P = 0.011) and − 0.36 ± 1.58 D (P = 0.030), respectively. Eyes with a thinner CCT and higher Kmax values exhibited a tendency for topographic flattening of ≥1.0 D (P = 0.003; P = 0.003). In the subgroup comparison, the Kmax values decreased significantly at 6 and 12 months after ATE-CXL in the group with CCT ≤ 450 μm (P = 0.018 and P = 0.045); the Kmax values of the group with Kmax > 65.0 D decreased significantly at 6 months postoperatively (P = 0.025). Conclusion ATE-CXL is a safe and effective treatment for keratoconus patients. Patients with thinner CCT and higher Kmax values are more likely to benefit from ATE-CXL.

scholarly journals Short-Term Effects of Two Types of Goggles On Intraocular Pressure and Anterior Eye Segment Biometrics

2021 ◽  
Author(s):  
Xu Zhang ◽  
Huixian Wang ◽  
Yuan Nie ◽  
Wenjing Li
Keyword(s):  
Intraocular Pressure ◽  
Anterior Chamber ◽  
Corneal Thickness ◽  
Anterior Segment ◽  
Anterior Chamber Depth ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Chamber Volume ◽  
Significant Difference ◽  
Anterior Eye Segment

Abstract Background: To evaluate and compare the changes in intraocular pressure and anterior eye segment biometrics,during and after wearing two types of commonly used swimming goggles.Methods: In a cross-sectional study, a total of 40 healthy adults aged between 18 and 60 years old were selected to wear two kinds of common swimming goggles (ocular socket and orbital goggles). Intraocular pressure and anterior segment biometry were evaluated before wearing, at 2 and 5 minutes of wearing, and at 5 minutes after removing the goggles. Intraocular pressure (IOP), corneal front keratometry values (K1, K2, Km), central corneal thickness (CCT), central anterior chamber depth (ACD), anterior chamber volume (ACV), and anterior chamber angle (ACA) were measured.Results: The IOP at 2 minutes (21.0±2.2 mmHg) and 5 minutes (21.2±2.3 mmHg) was significantly higher than before wearing goggles (17.7± 2.1 mmHg). The IOP after the goggles were removed and at 5 minutes after the goggles were removed was 18.4±2.3 mmHg and 17.7±2.1 mmHg, respectively. ACV, ACD, and ACA values all decreased while the googles were worn. After the goggles were removed, these changes gradually returned to baseline values, with no significant difference in the values before and after.Conclusion: This study proves that wearing orbital goggles can lead to an acute increase in IOP and a slight decrease in ACV, ACD, and ACA. However, once the goggles are removed, these indicators return to baseline levels, showing that wearing orbital goggles has no significant lasting effect on IOP and anterior segment parameters.

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