scholarly journals Comparative Evaluation of 0.2% Chlorhexidine Mouth Rinse with and without an Antidiscoloration System: A Clinical Study

2017 ◽  
Vol 7 (1) ◽  
pp. 53-56 ◽  
Author(s):  
Sidheshwar G Phad

ABSTRACT Introduction Chlorhexidine (CHX) is considered the gold standard agent for its clinical efficacy in chemical plaque control. The addition of other active ingredients may even reduce the antiplaque effectiveness. New mouthwash containing CHX with addition of an antidiscoloration system (ADS), i.e., Plasdone K-29/32, that claims to bind to stains, increases their solubility in water and effects their removal; thus the mouthwash promises not only to prevent plaque formation but also to avoid staining. Aim To clinically evaluate the efficacy of a 0.2% CHX mouth rinse with and without an ADS. Materials and methods The present study was a tripleblinded, prospective, cohort, and crossover study. This study consisted of 15 subjects. Supragingival scaling and polishing were done and then subjects were asked to rinse with a randomly allocated mouthwash for 15 days. Subjects used either mouthwash A (0.2% CHX with ADS) or mouthwash B (0.2% CHX). After 15 days, the discoloration index and plaque index (PI) were recorded. After 15 days washout period, on the 30th day from baseline, supragingival scaling and polishing were carried out, and each subject used the subsequent mouthwash. On 45th day from baseline, the discoloration and PIs were recorded and comparisons were made. Results No significant difference in the PI between groups I and II mouthwash was seen (p≥0.05), whereas significant difference was found in the discoloration index between groups I and II mouthwash (p≤0.05). Conclusion The addition of Plasdone does not reduce the efficacy of CHX mouthwash. The current study also proved that CHX with ADS caused less staining than CHX alone. How to cite this article Pereira R, Phad SG. Comparative Evaluation of 0.2% Chlorhexidine Mouth Rinse with and without an Antidiscoloration System: A Clinical Study. J Contemp Dent 2017;7(1):53-56.

2011 ◽  
Vol 12 (4) ◽  
pp. 221-224 ◽  
Author(s):  
AU Chaudhari ◽  
VM Karhadkar ◽  
PF Waghmare ◽  
AS Jamkhande

ABSTRACT Aim To compare the efficacy of turmeric mouthwash and chlorhexidine gluconate mouthwash in prevention of gingivitis and plaque formation. Materials and methods A total of 100 randomly selected subjects visiting the Department of Periodontology at Bharati Vidyapeeth Deemed University, Dental College and Hospital, were considered for the study. The gingival index (GI) by Loe and Silness was recorded which was followed by Turesky- Gilmore-Glickman modification of Quigley Hein plaque index (TQHPI) at 0, 14 and 21 days. Individuals who gave an informed consent, subjects in the age group of 25 to 35 years with having fair and poor gingival index scores and a score >1 for plaque index, were included in the study. Results Results showed statistically significant reduction (p < 0.05) in mean plaque index (PI) with chlorhexidine gluconate mouthwash when compared with turmeric mouthwash. No significant difference in mean gingival index (GI) was seen when chlorhexidine mouthwash was compared with turmeric mouthwash. Significant reduction in total microbial count (p < 0.05) was observed in both the groups. No significant difference was observed in total microbial count when chlorhexidine mouthwash was compared with turmeric mouthwash. Conclusion From the above observations, it can be concluded that chlorhexidine gluconate as well as turmeric mouthwash can be effectively used as an adjunct to mechanical plaque control methods in prevention of plaque and gingivitis. Chlorhexidine gluconate has been found to be more effective when antiplaque property was considered. Clinical significance From this study, it could be stated that turmeric is definitely a good adjunct to mechanical plaque control. Further studies are required on turmeric based mouthwash to establish it as a low cost plaque control measure. How to cite this article Waghmare PF, Chaudhari AU, Karhadkar VM, Jamkhande AS. Comparative Evaluation of Turmeric and Chlorhexidine Gluconate Mouthwash in Prevention of Plaque Formation and Gingivitis: A Clinical and Microbiological Study. J Contemp Dent Pract 2011;12(4): 221-224.


2010 ◽  
Vol 9 (1) ◽  
pp. 1
Author(s):  
Erry Mochamad Arief ◽  
Noor Dina Binti Adnan ◽  
Raja Azman Raja Awang

Plaque control is the main method for preventing periodontal diseases. Chlorhexidineia a gold standard mouthrinse but it has a side effect which limits its use. Triclosanwhich does not have side effects was used to evaluate its efficacy againstchlorhexidine. This experiment aimed to evaluate the effect of chlorhexidine andtriclosan on undisturbed plaque formation for 72 hours. Two groups, chlorhexidineand triclosan, respectively consists of 14 volunteers refrained from all mechanicaloral hygiene measures for the following 72 hours and rinsed instead twice daily for 1minute with 15 mL of either chlorhexidine or triclosan. The plaque accumulation wasassessed after 24, 48 and 72 hours using Modified Quigley-Hein Score. The medianplaque score between both groups on day 1 was not significantly different (p= 0.625),but the score on day 2 and day 3 were significantly different (p= 0.007 and 0.017respectively). The score between day 1 and day 3 on subjects using chlorhexidine wasnot significantly different (p= 0.109) unlike on subjects using triclosan (p= 0.003).The conclusion was chlorhexidine is more effective in controlling plaque formationcompared to triclosan.


2017 ◽  
Vol 5 (1) ◽  
pp. 6
Author(s):  
Jippy R.S. ◽  
Ananda S.R. ◽  
Jithesh Jain

Background: Herbal mouthrinses have been recently introduced with the objective of achieving effective plaque control. Till date, chlorhexidine has been a gold standard with regard to anti-plaque agents.Objectives: To compare the effeciveness of the herbal mouthrinse (Hiora) against chlorhexidine mouthrinse.Methods:The study is a randomized, double blind, crossover clinical study. At the baseline, the volunteers brush their teeth using toothpaste without any active ingredient for 2 minutes. Oral prophylaxis was performed to ensure that the teeth are free of plaque, stains and calculus. Each subject was randomly assigned to both the experimental groups. During the trials, the volunteers were rinsed their mouths, according to the assigned random sequence of treatments: Chlorhexidine as chemical and HiOra as herbal mouthrinse. Both the mouthrinses were packed in similar coloured bottles but labeled differently and randomly administered to the subjects by a blinded operator. Each subject received oral and written instructions on the use of mouth rinses. After one week, the study subjects were asked to suspend their oral hygiene for 24 hours, and accumulated plaque was re-evaluated with erythrosine. The plaque index was recorded in the six selected teeth at the end of the trial. After the trial period, the usual oral hygiene habits resumed.Results: There were no statistically significant differences between herbal and chemical mouthrinses.Conclusion: Herbal mouth rinses may be as effective as chlorhexidine as chemical anti-plaque agents with fewer side effects.


2021 ◽  
Vol 10 (38) ◽  
pp. 3360-3364
Author(s):  
Hanusha Bathula ◽  
Chiranjeevi Vedula ◽  
Harikrishna Reddy Sunkireddy ◽  
Venugopal Kunthsam ◽  
Manasa Dhulipala ◽  
...  

BACKGROUND The objective of the study was to determine the efficacy of Triphala as a preprocedural mouth rinse & comparing the efficacy with chlorhexidine and betadine in reducing the viable microbial load in dental aerosols. METHODS 32 patients with chronic periodontitis were randomly allocated into 4 groups (A, B, C & D) of 8 patients each who received 0.2 % chlorhexidine (CHX), 6 % Triphala (TRP), 2 % betadine and water respectively as a pre-procedural mouth rinse. Blood agar plates were placed on the operator’s chest area and the patient’s chest area for collecting the aerosols. The agar plates were then incubated at 370C for 48 hours and colony-forming units (CFUs) were counted. RESULTS CFU was significantly reduced in groups A, B & C compared to group D. Intergroup comparison showed no significant difference in the efficacy of 0.2 % CHX and 6 % TRP with P-value 0.058 in the operator’s area and with a significant difference of Pvalue 0.014 in the patient’s area. 2 % betadine was found to be least effective among the 3 test groups. The number of CFUs was greater at the patient’s chest area than that of the operator. CONCLUSIONS This study reinforces the importance of preprocedural mouth rinse. Triphala showed near equal efficacy to CHX, which is considered the gold standard in aerosol reduction and also better than 2 % betadine. Therefore, it can be considered as an alternative to CHX as a preprocedural mouth rinse. KEY WORDS Triphala, Chlorhexidine, Betadine, Aerosols, Colony Forming Units (CFUs)


2020 ◽  
Vol 73 (4) ◽  
pp. 148-152
Author(s):  
Kornél Vajda ◽  
László Sikorszki

Összefoglaló. Bevezetés: A laparoszkópia térhódítása a jobb oldali colon műtéteknél is nyilvánvaló. Ma legtöbb helyen a laparoszkóposan asszisztált jobb oldali hemikolektómia extrakorporális anasztomózissal a gold standard. A morbiditás randomizált vizsgálatok alapján még 30% körüli. A technikai fejlődés lehetővé tette az intrakorporális anasztomózist. Célkitűzés: Retrospektív módon elemezni rosszindulatú jobb oldali vastagbéldaganat miatt végzett laparoszkópos hemikolektómiák rövid távú eredményeit a két módszer összehasonlításával. Eredmények: 2018. 01. 01. – 2019. 12. 31. között 184 jobb oldali hemikolektómiát végeztünk, ezek közül 122 történt malignus betegség miatt. 51 esetben nyitott és 71 esetben laparoszkópos műtét történt. 37 férfi (átlagéletkor: 70,59 év) és 34 nő (átlagéletkor: 72,14 év) volt. 50 esetben extrakorporális (EA) és 21 esetben pedig intrakorporális anasztomózist (IA) végeztünk. Az EA csoportban 18, míg az IA csoportban 3 szövődmény alakult ki 30 napon belül (p = 0,067). Az EA csoportból 3, az IA csoportból 1 beteget veszítettünk el 30 napon belül (p = 0,66). Az átlagos ápolási idő az EA csoportban 9,48 (5–32) nap, míg az IA csoportban 6,52 (4–19) nap volt (p = 0,001) a szövődményes esetekkel együtt. A szövődményes esetek nélkül az EA csoportban 6,35 (5–10) nap, az IA csoportban pedig 5,55 (4–8) napnak bizonyult (p = 0,09). A műtéti idő pedig az EA csoportban 147 (90–240) perc, az IA csoportban pedig 146,47 (90–265) perc volt (p = 0,11). Konklúzió: Az irodalommal összhangban azt találtuk, hogy IA esetén kevesebb a szövődmény, ezzel is összefüggésben rövidebb az átlagos ápolási idő, és a műtéti időt tekintve nincs szignifikáns különbség. Ezeket figyelembe véve az intrakorporális anasztomózis javasolható jobb oldali laparoszkópos hemikolektómia esetén. Summary. Introduction: Laparoscopy became evident for right-sided colon surgery too. Today the laparoscopic-assisted right-hemicolectomy is the gold standard with extracorporeal anastomosis. Morbidity according to randomized trials is still approximately 30%. The development of the surgical technique resulted in the creation of intracorporeal anastomosis. Our aim was to compare the short-term results of the two methods. Aim: To analyse the short-term results of right-sided hemicolectomy that were performed due to malignant tumours with the comparison of the two methods. Results: A cohort of 184 right-sided hemicolectomy were performed from 01.01.2018 to 31.12.2019 from which 122 were operated on because of a malignant disease. 51 open and 71 laparoscopic operations were performed. The average age of 37 men and 34 women were 70.59 and 72.14 years, respectively. 50 patients underwent extracorporeal (EA) anastomosis and 21 intracorporeal (IA) anastomosis. Within 30 days the number of complications were 18 in the EA group and 3 in the IA group (p = 0.067). 3 from the EA group and 1 from IA group died within 30 days (p = 0.66). The average length of stay were 9.48 days in the EA group and 6.52 days in the IA group together with the complicated cases (p = 0.001) while 6.35 days and 5.55 days without the complicated cases (p = 0.09). The average duration of operation was 147 minutes in the EA and 146.47 minutes in the IA group (p = 0.11). Conclusion: We found concordance with the literature that there are fewer complications in case of IA which might be related to shorter length of stay. There is no significant difference between the surgical times. Bearing these facts in mind, IA might be suggested for right- sided laparoscopic hemicolectomy.


2019 ◽  
Vol 9 (1) ◽  
pp. 05-09
Author(s):  
Chitra Chakravarthy ◽  
◽  
Siddarth Goudar ◽  
Sanjay Sundar ◽  
Ravi Patil ◽  
...  

Author(s):  
Rajendra Joshi ◽  
N. B. Mashetti ◽  
Rakesh Kumar Gujar

Dushta Vrana is a common and frequently encountered problem faced in surgical practice. The presence of Dushta Vrana worsens the condition of the patient with different complications and may become fatal. Local factors on wound like slough, infection and foreign body, affect the normal process of healing. A healthy wound in a normal body heals earlier with a minimum scar as compared to a contaminated wound. Therefore in this study all the efforts are made to make a Dushta Vrana into a Shuddha Vrana. Once the Vrana becomes Shuddha, Ropana of the Vrana will start. The objective of the study was to evaluate the clinical efficacy of Jatyadi Taila and Jatyadi Ghrita in Dushta Vrana. Clinically diagnosed 60 Patients of Dushta Vrana were randomly divided into two groups, each consisting of 30 Patients. Group A were treated with the Jatyadi Taila and Group B was treated by Jatyadi Ghrita. The results observed was based on the relief obtained on the subjective and objective parameters taken for consideration for this study viz, size of ulcer, discharge, smell, pain, burning sensation, itching and granulation were found significant (P Lass Than 0.05). On the basis of assessment criteria and overall result of treatment, the patients of Jatyadi Taila group showed better results when compared to Jatyadi Ghrita group. Even though statistically there is no much significant difference between the two groups, but by seeing the effect on individual parameters (subjective and objective) and over all response, Jatyadi Taila seems to be effective when compared to Jatyadi Ghrita. It is having more Ropana qualities when compared to Shodhana.


Author(s):  
Sharmistha Sarkar ◽  
Dhruba Prasad Paul ◽  
Jayanta Ray

Background: Adverse maternal and perinatal outcomes are related to pregnancies spaced too closely together. Objective of present study was to compare the expulsion rate and complications between post placental IUCD insertion between caesarean section and vaginal delivery.Methods: This study was a prospective comparative study conducted in the department of Obstetrics and Gynecology, at Agartala Government Medical College over 1.5 Years (January 2016-June2017) All cases at term pregnancy delivering by caesarean section and vaginal delivery were divided into two different groups. Sample size of 105 in each group. Subjects recruited from-obstetrics OPD and casualty of Agartala Government Medical College (AGMC) and GB Pant Hospital expulsion rate and complications. Comparative evaluation of Expulsion rate and complications following post placental IUCD insertion between caesarean section and vaginal delivery at the end of six months, one year and one and half year.Results: There was no significant difference in either complications between the two groups (P value-.913) or outcomes (p value-.035). Expulsion rate 18.2% following vaginal delivery compared to those with intracaesarean insertion i.e 3.8%.Conclusions: The complications associated with postplacental Intrauterine device insertion is insignificant, still the awareness, acceptance and continuation are very low. Therefore Information, education Communication activity by the field workers must be enhanced to overcome this knowledge gap.


2021 ◽  
pp. 039156032110168
Author(s):  
Nassib Abou Heidar ◽  
Robert El-Doueihi ◽  
Ali Merhe ◽  
Paul Ramia ◽  
Gerges Bustros ◽  
...  

Introduction: Prostate cancer (PCa) staging is an integral part in the management of prostate cancer. The gold standard for diagnosing lymph node invasion is a surgical lymphadenectomy, with no superior imaging modality available at the clinician’s disposal. Our aim in this study is to identify if a pre-biopsy multiparametric MRI (mpMRI) can provide enough information about pelvic lymph nodes in intermediate and high risk PCa patients, and whether it can substitute further cross sectional imaging (CSI) modalities of the abdomen and pelvis in these risk categories. Methods: Patients with intermediate and high risk prostate cancer were collected between January 2015 and June 2019, while excluding patients who did not undergo a pre-biopsy mpMRI or a CSI. Date regarding biopsy result, PSA, MRI results, CSI imaging results were collected. Using Statistical Package for the Social Sciences (SPSS) version 24.0, statistical analysis was conducted using the Cohen’s Kappa agreement for comparison of mpMRI with CSI. McNemar’s test and receiver operator curve (ROC) curve were used for comparison of sensitivity of both tests when comparing to the gold standard of lymphadenectomy. Results: A total of 143 patients fit the inclusion criteria. We further stratified our patients into according to PSA level and Gleason score. Overall, agreement between mpMRI and all CSI was 0.857. When stratifying patients based on Gleason score and PSA, the higher the grade or PSA, the higher agreement between mpMRI and CSI. The sensitivity of mpMRI (73.7%) is similar to CSI (68.4%). When comparing CSI sensitivity to that of mpMRI, no significant difference was present by utilizing the McNemar test and very similar receiver operating characteristic curve. Conclusion: A pre-biopsy mpMRI can potentially substitute further cross sectional imaging in our cohort of patients. However, larger prospective studies are needed to confirm our findings.


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