Spontaneous Cholecystocutaneous Fistula

Author(s):  
Rajesh Abbey

ABSTRACT Spontaneous biliary fistulae are encountered, not very rarely, in one's surgical practice. These fistulae are of three types: Internal, external, and combined. Internal spontaneous biliary fistulae are the commonest. External fistulae could be spontaneous or because of therapeutic, iatrogenic, or traumatic reasons are extremely rare. Spontaneous cholecystocutaneous fistula (SCCF), secondary to calculous cholecystitis, is an extremely rare presentation in the present-day scenario. It used to be quite common before the year 1900, but is very rare now because of better management of cholecystitis and cholelithiasis. Usually, SCCF is a complication of neglected chronic cholelithiasis. This is seldom seen today because of the early diagnosis and better management made feasible by ultrasound as first-line investigation, broad spectrum antibiotics, and effective surgical management of biliary tract diseases. It is a very rare case of 35-year-old female patient presenting in the outpatient department, with the multiple stones carefully preserved, which she had been extruding through the fistulous opening in the umbilicus, for the last 1 year. She was investigated and was operated for the same condition. Though the entity is very rare, clinicians should keep this condition in mind while examining any case of chronic discharging sinus or fistula on the abdominal wall, particularly the wound extruding stones in which case the diagnosis is selfrevealing. In the absence of positive history of expelling stones, the diagnosis can be confirmed by computerized tomogram fistulography. Though the early diagnosis and improvement in the management of gallbladder disease has improved tremendously, the possibility of this condition arising mostly from the neglected gallbladder disease should always be kept in mind as such cases are again being reported from all over the world. How to cite this article Abbey R. Spontaneous Cholecystocutaneous Fistula. Int J Adv Integ Med Sci 2016; 1(4):196-198.

1998 ◽  
Vol 31 (122) ◽  
pp. 202-221 ◽  
Author(s):  
G.K. Peatling

John Kells Ingram was born in County Donegal in 1823. His ancestry was Scottish Presbyterian, but his grandparents had converted to Anglicanism. He was educated at Trinity College, Dublin, the most prestigious academic institution in nineteenth-century Ireland. In a brilliant academic career spanning over fifty years he proceeded to occupy a succession of chairs at the college. His published work included an important History of political economy (1888), and he delivered a significant presidential address to the economics and statistics section of the British Association for the Advancement of Science (1878). Ingram influenced, and was respected by, many contemporary social and economic thinkers in the British Isles and elsewhere. In an obituary one of Ingram’s friends exaggerated only slightly in describing him as ‘probably the best educated man in the world’. Yet contemporary perspectives on Ingram’s career were warped by one act of his youth which was to create a curious disjunction in his life. In 1843, when only nineteen years old, Ingram was a sympathiser with the nationalist Young Ireland movement. One night, stirred by the lack of regard shown for the Irish rebels of 1798 by the contemporary O’Connellite nationalist movement, he wrote a poem entitled ‘The memory of the dead’, eulogising these ‘patriots’. Apparently without much thought, Ingram submitted the poem anonymously to the Nation newspaper. It appeared in print on 1 April 1843 and, better known by its first line, ‘Who fears to speak of ’Ninety-Eight?’, became a popular Irish nationalist anthem.


Author(s):  
Cristina Bragança ◽  
Inês Gonçalves ◽  
Luísa Guerreiro ◽  
Maria Janeiro

AbstractTuberculosis is an infectious disease caused by Mycobacterium tuberculosis. According to data from the World Health Organization, this disease remains one of the leading causes of death worldwide. Although it most commonly affects the lungs, tuberculosis can compromise any organ. The present study reports a rare case of vulvar tuberculosis in a postmenopausal woman with a history of asymptomatic pulmonary and pleural tuberculosis, with no prior documented contact with the bacillus. Diagnosis was based on vulvar lesion biopsies, with histological findings suggestive of infection and isolation of M. tuberculosis by microbiological culture and polymerase chain reaction (PCR) essays. The lesions reverted to normal after tuberculostatic therapy.


2021 ◽  
Vol 12 ◽  
Author(s):  
Sherehan Ibrahim ◽  
Jamie R. Lowe ◽  
Carolyn T. Bramante ◽  
Surbhi Shah ◽  
Nichole R. Klatt ◽  
...  

Metformin is the first-line medication for type 2 diabetes, but it also has a long history of improved outcomes in infectious diseases, such as influenza, hepatitis C, and in-vitro assays of zika. In the current Covid-19 pandemic, which has rapidly spread throughout the world, 4 observational studies have been published showing reduced mortality among individuals with home metformin use. There are several potential overlapping mechanisms by which metformin may reduce mortality from Covid-19. Metformin’s past anti-infectious benefits have been both against the infectious agent directly, as well as by improving the underlying health of the human host. It is unknown if the lower mortality suggested by observational studies in patients infected with Covid-19 who are on home metformin is due to direct activity against the virus itself, improved host substrate, or both.


2014 ◽  
Vol 52 (196) ◽  
pp. 1017-1019 ◽  
Author(s):  
Palla Bhattarai ◽  
Louidson Pierr ◽  
Adebayo Adeyinka ◽  
Swayam Sadanandan

A previously healthy 16-year-old male presented with a two day history of persistent epigastric pain. His physical examination was significant for tenderness in the left hypochondriac region with a palpable spleen 2cm below the left sub-costal margin. A CT scan of the abdomen showed a splenic infarct. Heterophile and EBV VCA IgM antibody test were positive. This is a rare case of infectious mononucleosis presenting with splenic infarct in an adolescent male without comorbidities.  Keywords: infectious mononucleosis; splenic infarct.


2015 ◽  
Vol 1 (3) ◽  
pp. 58-59
Author(s):  
Anil Kumar H ◽  
V Vikranth

ABSTRACT Dermatomyositis is a rare type of inflammatory myopathy that represents the largest group of acquired and potentially treatable cause of skeletal muscle weakness. It is characterized by chronic muscle inflammation accompanied by muscle weakness. Here, we present a case of an elderly female who presented with a history of pain in bilateral arm, forearm, thigh, and leg associated with swelling and with a history of rash over the upper extremities. On examination, edema with tenderness was present on both upper limb and lower limb. We also noticed erythematous rash over the arm, forearm, nose, and forehead. Investigations showed hyponatremia, with elevated Cretatinc phosphokinase levels. Hence, a provisional diagnosis of hyponatremia-induced rhabdomyolysis was made. On further evaluation, urine for myoglobin was negative, and in view of the accompanying rash and minimal improvement with sodium correction a provisional diagnosis of dermatomyositis with hyponatremia/hyponatremia-induced rhabdomyolysis was made. Diagnosis of dermatomyositis was confirmed by the muscle biopsy. Dermatomyositis may be accompanied by hyponatremia and atypical rash. It can also be confused with hyponatremic rhabdomyolysis. Dermatomyositis is also a rare presentation and it may be a paraneoplastic manifestation. How to cite this article HAK, V Vikranth. A Rare Case of Dermatomyositis with Hyponatremia. J Med Sci 2015;1(3):58-59.


2020 ◽  
Vol 12 (2) ◽  
pp. 1083-1087
Author(s):  
Jason Mikail Amper

Background: Thoracic Outlet Syndrome is one of the rarest diseases in the world with not a lot of information behind it. It is a collection of symptoms caused by compression in the neurovascular bundle exiting the Thoracic Outlet. The Thoracic Outlet is a structure under the neck between the first costae and the clavicle. Objective: To know more about Thoracic Outlet Syndrome comprehensively. Methods: Using literature studies from national and international journals by summarizing the topic of discussion and comparing the results presented in the article. Results: Thoracic Outlet Syndrome is a disease with various etiologies. The. The diagnosis of the disease is determined by the symptoms exhibited. Thoracic Outlet Syndrome can be divided into 3 types, which are Arterial Thoracic Outlet Syndrome, Venous Thoracic Outlet Syndrome, and Neurogenic Thoracic Outlet Syndrome. Physical rehabilitation and change in lifestyle remain the first-line treatment for this disease, with complications, surgery is recommended. Conclusion: There are many things still unknown to Thoracic Outlet Syndrome, early diagnosis is essential to diagnose the type of Thoracic Outlet Syndrome to determine the correct treatment for the type.


2015 ◽  
Vol 20 (2) ◽  
pp. 150-152 ◽  
Author(s):  
Annie R. Langley ◽  
Paul Manley ◽  
Yuka Asai

Background: Psoriasis and vitiligo are common dermatologic conditions with underlying autoimmune etiologies. There are few reports of concomitant and colocalized disease. Several theories have been proposed to explain this rare presentation. Objective: The objective of this study was to present a rare case of a concomitant and colocalized presentation of vitiligo and psoriasis. Methods: Case report. Results: A 72-year-old male was referred for treatment of a 30-year history of psoriasis and 5-year history of colocalized vitiligo. The patient had no other underlying autoimmune diseases including psoriatic arthritis. Conclusion: Clinicians should be aware of the possible concomitance and colocalization of psoriasis and vitiligo. Further research is needed to elucidate the common pathways leading to the concomitance and colocalization of these diseases.


2020 ◽  
Vol 25 (2) ◽  
pp. 134-139
Author(s):  
Ji-Young Kim ◽  
Ji-In Jeon ◽  
Hak Chang

BCG (Bacille Calmette-Guérin) vaccine has been administered safely to billions of people all over the world. The Tokyo-172 strain has reported to have a lower virulence and side effects than other strains. BCG osteomyelitis of distal radius is a very rare but serious complication due to generalized dissemination of BCG. We report a rare case of BCG osteomyelitis of the distal radius in a 21-month-old girl who had no underlying disorders. Although uncommon, BCG osteomyelitis should be considered a possible complication of BCG vaccination under certain clinical features for early diagnosis and proper treatment.


Author(s):  
Francis Essien ◽  
Christine Persaud ◽  
David Dado ◽  
Joshua Tate ◽  
George Shahin

Large cell neuroendocrine carcinoma (LCNEC) was first proposed by Travis et al. in 1991 and subsequently classified as high grade neuroendocrine carcinoma (HGNEC) by the world health organization. It is a rare tumor with unclear clinicopathologic features. Herein, we describe a rare case of LCNEC with a unique Cushing’s presentation.


2021 ◽  
Vol 1 ◽  
pp. 5
Author(s):  
Faham Khamesipour ◽  
Saeed Nezaratizade ◽  
Bahareh Basirpour ◽  
Bahareh Chelgerdi Dehkordi ◽  
Sana Sadat Afzal ◽  
...  

Dirofilariasis is a metazoonoses transmitted by certain mosquito genera (Culicidae: Diptera). Chiefly canids are the reservoirs of Dirofilaria spp. This article analyzed all published records and researches relevant to Dirofilaria in Iran, to provide a basis for future studies in Iran and around the world. All of the important data from human and animal cases that included the pathogen and its reservoir, dispersion, and retrospective studies were investigated and analyzed. Furthermore, the natural history of parasites, pathogenicity, diagnosis, treatment, control, and the final status of the disease in the world was briefly mentioned. Two species of the genus Dirofilaria, Dirofilaria immitis (canine heartworm) and Dirofilaria repens, are detected in Iran. Till now, 13 human cases have been formally reported including seven subcutaneous and three ocular cases of D. repens, a four cases of D. immitis, including a rare case in testicular hydrocele, one ocular and one pre-ocular, a subconjunctival and two pulmonary cases suspected to be D. immitis. Animal and human infections have been recorded in 11 provinces of Iran. Different investigators have reported D. immitis in dogs (with the frequency of 0.95–62.8%), jackals (2.5 57.4%), foxes (5.7–50%), wolves (20–50%), and cats (0.8%) and D. repens in dogs (1.4–60.8%) and jackals (10%) in different areas of the country. The reports on Dirofilaria in Iran are to some extent scattered as regarded to distribution and other features of the disease. More studies should be taken in dirofilariasis in Iran, specifically in regions from where there are no reports.


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