scholarly journals Multidrug Resistant Bacteria in Urinary Tract Infection: A Constant Threat to a Tertiary Care Health Set-up in North India

2018 ◽  
Vol 1 (1) ◽  
pp. 15-21
Author(s):  
Sanjay S Kaira ◽  
Anuradha Makkar ◽  
Pragyan S Panda ◽  
Priyanka Banerjee ◽  
ID Khan
Keyword(s):  
Urinary Tract Infection ◽  
Urinary Tract ◽  
Tract Infection ◽  
Tertiary Care ◽  
Multidrug Resistant ◽  
North India ◽  
Resistant Bacteria ◽  
Multidrug Resistant Bacteria ◽  
Care Health ◽  
Set Up

scholarly journals Prevalence of multidrug resistant bacteria in causing community acquired urinary tract infection among the patients attending outpatient department of Seti Zonal Hospital, Dhangadi, Nepal

2015 ◽  
Vol 3 (1) ◽  
pp. 55-59 ◽  
Author(s):  
Tek Raj Awasthi ◽  
Narayan Dutt Pant ◽  
Puspa Raj Dahal
Keyword(s):  
Urinary Tract Infection ◽  
Urinary Tract ◽  
Tract Infection ◽  
Past History ◽  
Multidrug Resistant ◽  
Outpatient Department ◽  
Public Health Issue ◽  
Resistant Bacteria ◽  
Biochemical Tests ◽  
Multidrug Resistant Bacteria

Involvement of multidrug resistant bacteria in causing community acquired infection is very serious public health issue. The main objective of our study was to determine the prevalence of multidrug resistant bacteria in causing community acquired urinary tract infection. In this study we cultured the 384 mid stream urine samples collected aseptically from the patients attending outpatient department of Seti zonal hospital and having no past history of hospitalization. The organisms isolated were identified by using conventional biochemical tests and antimicrobial susceptibility testing was performed by Kirby Bauer disc diffusion technique. Out of total 384 samples 98 (25.52%) samples showed significant bacterial growth. The most prevalent bacterium isolated was Escherichia coli. 42.86% of the bacteria isolated were found to be multidrug resistant (MDR). The involvement of such large numbers of multidrug resistant bacteria in causing community acquired urinary tract infection is very serious issue and cannot be neglected. And some abrupt initiatives should be taken by the responsible authorities to improve or at least avoid the further worsening of the situation.Nepal Journal of Biotechnology. Dec. 2015 Vol. 3, No. 1: 55-59

scholarly journals Trimethoprim - Sulfamethoxazole in Combination With Meropenem Orpolymyxin is Effective in Management of Acinetobacter Baumannii Associated Pneumonia and Urinary Tract Infection

2020 ◽  
Vol 5 (1) ◽  
pp. 990-994
Author(s):  
Niraj Kumar Keyal ◽  
Niru Nepal ◽  
Amid Bhujel
Keyword(s):  
Intensive Care Unit ◽  
Urinary Tract Infection ◽  
Antibiotic Resistance ◽  
Intensive Care ◽  
Urinary Tract ◽  
Tract Infection ◽  
Acinetobacter Baumannii ◽  
Multidrug Resistant ◽  
Resistant Bacteria ◽  
Multidrug Resistant Bacteria

Acinetobacter baumanniiis a common multidrug resistant bacteria that causes pneumonia and urinary tract infection in intensive care unit and requires dual antibiotic for effective management. There are limited expensive antibiotics that are active against. Acinetobacter baumannii. Trimethoprim - Sulfamethoxazole is a cheap, older and easily available antibiotic that can be used in combination with Meropenem or Polymyxin for treatment to decrease antibiotic resistance. This case presentation of three patients describes the successful treatment of hospital acquired Pneumonia and Urinary Tract Infection by Acinetobacter baumannii with Trimethoprim - Sulfamethoxazole in combination with Meropenem and Polymyxin that lead avoidance of costly drugs and decrease in antibiotic resistance. Antibiotic resistance and lack of newer effective antibiotic against multidrug resistant bacteria like Acinetobacter baumannii is a common problem in intensive care unit. Trimethoprim -Sulfamethoxazole may help in combating this problem.

scholarly journals Biofilm Production and Antimicrobial Resistance among Uropathogens in Pediatric Cases: a Hospital Based Study

2018 ◽  
Vol 16 (2) ◽  
pp. 178-183
Author(s):  
Dhiraj Shrestha ◽  
Pratigya Thapa ◽  
Dinesh Bhandari ◽  
Hiramani Parajuli ◽  
Prakash Chaudhary ◽  
...  
Keyword(s):  
Urinary Tract Infection ◽  
Urinary Tract ◽  
Antimicrobial Resistance ◽  
Tract Infection ◽  
Tertiary Care ◽  
Multidrug Resistant ◽  
Resistance Pattern ◽  
E Coli ◽  
Biofilm Production ◽  
Resistance Patterns

Background: The study was designed to provide account of etiological agents of urinary tract infection in pediatric patients and the antimicrobial resistance pattern plus biofilm producing profile of the isolates.Methods: The prospective study was conducted in Alka Hospital, Nepal with 353 clean catch urine samples from children. It was obtained during July 2014 to January 2015 which were first cultured by semi-quantitative method, followed by antimicrobial susceptibility testing and biofilm production assay on Congo red agar. Multidrug- resistance, extensively drug- resistance and pandrug- resistance among isolates were considered as per international consensus.Results: Out of 353 samples, 64 (18.13%) showed positive growth in culture, confirming urinary tract infection. E. coli, 44 (68.8%) was the predominant organism followed by Klebsiella spp. 6 (14.1%). Most E. coli were sensitive to amikacin (93.2%) followed by nitrofurantoin (86.4%), and highly resistant to ampicillin (95.5%). Of 64 isolates, 23 (35.93%) were found to be multidrug- resistant strains. Biofilm was produced by 36 (56.25%) isolates.Conclusions: This study showed higher biofilm production and resistance to in-use antibiotics rendering ineffective for empirical use. Regular surveillance of resistance patterns should be done to regulate multidrug- resistant bugs and to ensure effective management of urinary tract infection in children in a tertiary care setups.Keywords: AMR; antimicrobial resistance; biofilm; urinary tract infection; UTI.

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