scholarly journals Drug utilization pattern of antidiabetic drugs among indoor diabetic patients in a tertiary care teaching hospital, Jorhat

Biomedicine ◽  
2021 ◽  
Vol 40 (4) ◽  
pp. 512-515
Author(s):  
Gautam Sahu ◽  
Swapnanil Gohain ◽  
Angelene Brahma

Introduction and Aim: Diabetes is an opportunistic killer. Approximately 77 million people in India suffer from diabetes. A person develops diabetes due to genetic predisposition, family history, obesity, lack of physical activity, diet low in fruits and vegetables. Modification of life style and pharmacotherapy of diabetes are often indicated to control diabetes and emergence of complications. Therefore, the present study was undertaken to evaluate the prescription pattern of antidiabetic drugs among indoor patient with adherence to WHO core prescribing indicator. Materials and Methods: A retrospective observational study was conducted for a period of six months and 140 case sheets of indoor diabetic patients admitted in Medicine department were collected from MRD office after prior approval from IEC. The data were analysed using descriptive statistics. Results: The study showed male preponderance of 75.71% in comparison to female 24.29%. The pattern of antidiabetic prescribed showed highest prescription rate of various preparations of insulin (68.57%) with regular insulin most commonly prescribed preparation (64.58%). Among oral antidiabetic drugs metformin (42.86%) was most commonly used. The percentage of drug prescribed in generic name was 36.36% and the percentage of drugs prescribed from National List of Essential Medicines (NLEM) was found to be 69.7%. Conclusion: The study provided substantial information about the prescribing practices of physicians and also paved a way to formulate prescribing policies at our institution.

Author(s):  
Salman H. Rizvi ◽  
Ujwala P. Gawali ◽  
Prashant S. Mishra

Background: With the surge of basic and clinical research activities, and subsequent recognition of newer dermatological disorders; dermatology is now considered to be one of the most important specialties in a healthcare setup. Dermatological problem in India manifests as primary and secondary cutaneous complaints. The aim of this study was to assess current prescribing practices among physicians for dermatology patients in tertiary care hospital.Methods: A prospective, observational and cross-sectional study was conducted in Department of Pharmacology in collaboration with Department of Dermatology in a tertiary healthcare hospital. As per inclusion criteria, patients visiting Dermatology Outpatient department (OPD) from October 2018 to December 2018 were enrolled in the study.Results: The average number of drugs per encounter was 4.9. 100% of the drugs were prescribed by their generic name and those prescribed from World Health Organization (WHO) list of essential medicines were 68.9%. Analysis of polypharmacy showed maximum 11 and minimum 2 drug was prescribed. Overall analysis of the drugs showed, the most common route of administration was orally. Antihistamines, antifungals and steroids constitute the major bulk of drug prescribed.Conclusions: In our study, though polypharmacy was found but it was necessary as per the conditions. Anti-fungal, antihistamines and steroids were the most common drugs prescribed. Prescriptions with injections and steroids were less in the study population. All the drugs were prescribed by their generic name and most were present in the essential list of medicines. Use of Nonsteroidal anti-inflammatory drugs (NSAIDs) was higher in our study as compared to other studies.


Author(s):  
Shweta Sharma ◽  
S. C. Chopra ◽  
D. K. Sharma ◽  
Juhi Singla ◽  
Vinod Kapoor

Background: Diabetes Mellitus is a chronic disease and its life-long management causes burden on lifestyle and financial condition of the patients. Drug utilization studies provide useful insights into the current prescribing practices.Methods: To evaluate the drug utilization pattern of anti-diabetic drugs in diabetic patients. A prospective observational study was carried out in adult diabetic patients visiting the Wards and Outpatient Department of General Medicine of a tertiary care hospital. The demographic data and utilization of different classes of anti-diabetic agents as well as individual drugs were analyzed.Results: In 125 patients (Male-65, Female-60), a total of 379 drugs (average 3.032±2.05) were used per day, out of which 76 (20.05%) were rational fixed dose combinations (FDCs) and 261 (68.86%) were prescribed from National List of Essential Medicines (NLEM) 2015. The number of drugs prescribed to be ingested was 326 (86.01%) and 63 (16.62%) were injectables.Conclusions: It was found that the prescription tendencies of the doctors were quite rational. More improvement can be done by sensitizing them to prescribe more drugs from NLEM. The limitations in the affordability of rural population should be taken care of while prescribing drugs for this chronic disease.


2019 ◽  
Vol 29 (Supplement_4) ◽  
Author(s):  
A S Aguadé ◽  
C Gastaldi-Ménager ◽  
D Karsenty ◽  
P Fontaine ◽  
A Fagot-Campagna

Abstract Objective To describe the changing patterns in the use of the various classes of antidiabetic drugs in a cohort of patients newly treated for diabetes from 2008 to 2015 on the basis of comprehensive health insurance data. Methods General scheme beneficiaries 45 years and older were identified in the French National Health Data System (SNDS) as newly treated when antidiabetic drugs were dispensed on at least 3 different dates in 2008 and at least once during the last 4 months of 2008, but were dispensed less than 3 times in 2006-2007. Treatment regimens for the last 4 months of each year were defined for this cohort. Results 158,000 people (53% men, mean age 62 years) initiated antidiabetic drug therapy in 2008: monotherapy (without insulin): 74%, dual therapy: 17%, treatment with 3 or more drugs: 3%, and insulin therapy: 7%. The proportion of patients taking monotherapy decreased by 13 percentage points during the second year and only 32% of the cohort was treated by monotherapy 8 years after starting treatment. The proportions of patients taking dual therapy increased by 4 percentage points (21% in 2015), triple therapy increased by 8 percentage points (11%), a combination of insulin+other antidiabetics increased by 4 percentage points (7%) and insulin alone remained stable (4%). At the last quarter of 2015, 12% of patients did not receive any antidiabetic drugs and 13% had died. The creation of a cohort of diabetic patients newly treated in 2013 demonstrated changing prescribing practices: a lower proportion of monotherapy in the first year of treatment, but a growing use of metformin. Conclusions Treatment was intensified during the first 8 years for one half of the cohort. The maximal dosage of Metformin is not used before introducing a second antidiabetic in 1 case in 2. Insufficient use of Metformin, in general and in terms of dosage, was observed, although this use is improving. Key messages Initiation of antidiabetic drug therapy in people 45 years and older consisted of monotherapy in 3/4 of cases in 2008. Insufficient use of Metformin, in general and in terms of dosage, was observed, although this use is improving.


2021 ◽  
Vol 1 (1) ◽  
pp. 21-28
Author(s):  
Deependra Prasad Sarraf ◽  
Bajarang Prasad Sah

Introduction: Assessment of drug utilisation pattern (DUP) based on World Health Organisation (WHO) drug prescribing indicators would enhance the standards of patient care at all levels of the healthcare. It helps to improve the quality of life in developing countries like Nepal. Objective: To assess DUP in patients admitted in ear, nose and throat inpatient department at a tertiary hospital in Eastern Nepal using the WHO prescribing indicators. Methods: A hospital based cross-sectional descriptive study was carried out in 96 patients in ENT department of a tertiary care teaching hospital from February-April 2019. Pre-designed proforma was used to collect the relevant data from the medical case sheets and drug charts. Descriptive statistics were calculated using Microsoft Excel 2010. Results: Out of 96 patients, 52 (54.17%) were female. Most of the patients (46, 47.18%) were pre­scribed four drugs. Combination of Ibuprofen and Paracetamol (77, 19.74%) was the commonest prescribed drug. Ceftriaxone (62, 63.92%) was the most frequently prescribed systemic antibiotic. The average number of drugs per prescription was 4.06. None of the drugs were prescribed by generic name. Out of 360 drugs, only 118 (30.26%) were prescribed from National List of Essential Medicines (NLEM) and 117 (30.00%) drugs were fixed drug combinations. Ninety two (95.83%) patients had been prescribed at least one antibiotic. Conclusions: The prescribing practices of essential medicines, generic drugs, antibiotics and inject­able drugs showed deviation from the standard recommended by the WHO. The prescribers should be motivated to enhance prescription of drugs by generic names and from NLEM.


2020 ◽  
Vol 2020 ◽  
pp. 1-7
Author(s):  
Ali Hassan Alhaiti ◽  
Mohammed Senitan ◽  
Wireen Leila T. Dator ◽  
Chandrakala Sankarapandian ◽  
Nadiah Abdulaziz Baghdadi ◽  
...  

Aim. To analyse the prevalence of self-care practices in T2D patients in KSA. Methods. The study was conducted in King Fahad Medical City (KFMC) in Saudi Arabia, and 385 patients were selected as samples. Data were collected using the Summary of Diabetes Self-Care Activities-Arabic (SDSCA) and consisted of 14 items related to self-care activities of T2D patients related to management and control of disease and four other aspects related to education and advice from healthcare members regarding management of T2D. Results. The self-care attributes including adherence to medication commitment activities ( M = 6.13 , SD = 1.25 ) were the most practised of all the domains. Glucose monitoring ( M = 4.15 , SD = 2.42 ) and foot care ( M = 3.28 , SD = 1.69 ) were at an average level, and adherence to the diet plan and exercise was found to be at a poor level ( M = 2.57 , SD = 1.73 and M = 2.13 , SD = 2.00 ) respectively. About 179 patients (74.3%) were found to be advised to follow a low-fat eating plan, and only 89 patients (36.9%) had received information concerning fruits and vegetables in their diet. More than 90% patients were found to be advised to strictly carry out exercise and blood sugar monitoring. Conclusion. It was found that adherence to self-care activities including diet, exercise, and foot care was relatively poor while intake of medication was strictly followed. The education provided by healthcare providers related to self-management attributes was found to be significant and had positive effects on the overall health and well-being of T2D patients.


Author(s):  
Ujwala P. Gawali ◽  
Salman H. Rizvi ◽  
Prashant S. Mishra

Background: Drug utilization study is of utmost importance in the elderly. The consumption of drug amongst elderly segment of society is maximum and many of them use at least three prescribed drugs, concurrently. One of the plausible explanation of usage of large number of medicines is prevalence of multi-morbidities as well as suffer from chronic and degenerative pathology amongst them along with the alteration of pharmacokinetics and pharmacodynamics of many drugs are altered with advanced age. Thus, the aim of this study was to assess current prescribing practices among physicians for geriatric patients in tertiary care hospital.Methods: A prospective, observational and cross-sectional study was conducted in Department of Pharmacology in collaboration with Department of Medicine in a tertiary healthcare hospital. As per inclusion criteria, patients visiting Medicine outpatient department (OPD) from 01 October 2018 to 31 December 2018 were enrolled in the study.Results: The average number of drugs per encounter was 4.1. 100% of the drugs were prescribed by their generic name and those prescribed from World Health Organization (WHO) list of essential medicines were 70.2%. Analysis of polypharmacy showed maximum 11 and minimum 1 drug was prescribed. Overall analysis of the drugs showed, the most common route of administration was orally. Drugs acting on cardiovascular system (CVS), gastrointestinal system (GI) system, analgesics and anti-inflammatory drugs and vitamins and mineral supplements constitute the major bulk of drug prescribed.Conclusions: In our study, though polypharmacy was found but it was necessary unavoidable, but was within the WHO standards of 1.6 to 4.8. Drugs acting on CVS and GI system were the most common drugs prescribed. Prescriptions with injections and steroids were less in the study population. All the drugs were prescribed by their generic name and most were present in the essential list of medicines.


Author(s):  
Dinesh Raj Neupane ◽  
Upendra N. ◽  
Jaiji Thomas ◽  
Jojymol K. Joy

Background: Diabetes has become a scourge to mankind. According to World Health Organization, over 366 million people are affected with diabetes worldwide and its number is likely to be doubled by 2030. The study was conducted to educate the patients regarding diabetes which may lead in improving the quality of life of the patients. However, prior to educating and intervening the patients regarding the disease, KAP study was conducted to assess the current status and behaviour of the patients towards Diabetes Mellitus (DM).Methods: The study was cross sectional study conducted for the period of six months starting from July 2019 to December 2019 in medicine department of Tertiary care teaching Hospital, Karnataka. Pre-structured questionnaires were formed for data collection.Results: In our current study, 60 (46.15%) were men and 70 (53.85%) women. Out of the total of ten knowledge question asked, average of men answering correctly were 29.5% and women answered correctly were 21% and rest were incorrect. Among the total of five attitude questions asked, average of 25.08% men agreed to correct response and 18% women agreed to correct response rest disagreed whereas in total of six practice questions average of 26.92% men and 14.61% women claimed that they practice the activities as per the questionnaires.Conclusions: Knowledge of diabetic patients was fairly good, attitude and practices were not satisfactory females showed relatively poor response towards the disease in comparison to male. We strongly feel that there is a need to design and develop individualized diabetes educational program to aware and educate people about diabetes.


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