scholarly journals PRE-EMPTIVE EFFECT OF INTRAVENOUS PARACETAMOL VERSUS INTRAVENOUS KETOROLAC ON POST-OPERATIVE PAIN AND SHIVERING AFTER SEPTOPLASTY UNDER GENERAL ANESTHESIA: A COMPARATIVE STUDY

2021 ◽  
Vol 71 (4) ◽  
pp. 1179-82
Author(s):  
Sanum Kashif ◽  
M Nasir Kundi ◽  
Taimur Azam Khan
Keyword(s):  
Placebo Group ◽  
Comparative Study ◽  
General Anesthesia ◽  
P Value ◽  
Post Operative Pain ◽  
Intravenous Paracetamol ◽  
Ethical Committee Approval ◽  
Prospective Comparative Study ◽  
American Society ◽  
Intravenous Ketorolac

Objective: To observe the pre-emptive effect of intravenous paracetamol versus intravenous ketorolac in preventing postoperative shivering and pain after septoplasty in postoperative care unit. Study Design: Prospective comparative study. Place and Duration of Study: Main Operation Theatre of Frontier Corps Hospital Quetta, from Sep to Dec 2019. Methodology: After ethical committee approval, 90 American Society of Anaesthesiologist (ASA-I patients, aged between 18-45 years, scheduled for septoplasty, were recruited and divided into three equal groups, Paracetamol (PA), Ketorolac (KE) and Placebo (PL) as per computer generated table. The paracetamol (PA) group (n=30) received 1gm intravenous paracetamol, ketorolac (KE) group (n=30) received 30mg intravenous ketorolac and group placebo (PL) received 100ml normal saline, 20 minutes before completion of surgery. Postoperative shivering and pain was assessed via four-point scale and visual analogue scale (VAS) respectively, in post-anesthesia care unit at 10 and 30 minutes post-extubation. Results: Mean visual analog scale (VAS) score in paracetamol group was 2.7 ± 1.41, ketorolac group was 2.3 ± 1.24 and in placebo group was 3.6 ± 1.44, with a p-value of 0.002. Mean four point shivering score in paracetamol group was 0.3 ± 0.55, ketorolac was 0.7 ± 0.78 and placebo group was 1.4 ± 1.00, with a p-value of <0.001. Conclusion: The effect of paracetamol is better than ketorolac in preventing pain and shivering after septoplasty under general anesthesia.

scholarly journals Comparative Evaluation of Effectiveness of Intravenous Paracetamol and Intravenous Diclofenac as Post-operative Analgesia in Laparoscopic Cholecystectomy

2018 ◽  
Vol 6 (2) ◽  
pp. 6
Author(s):  
Kalpana Kharbuja ◽  
Mahesh Sharma ◽  
Nil Raj Sharma
Keyword(s):  
Laparoscopic Cholecystectomy ◽  
Visual Analogue Scale ◽  
Analogue Scale ◽  
P Value ◽  
Anesthesia Induction ◽  
Chi Square ◽  
Rescue Analgesia ◽  
Post Operative Period ◽  
Post Operative Pain ◽  
Intravenous Paracetamol

Introduction: Though the development of minimally invasive surgery  has revolutionized the field of surgery,  post-operative pain is still a significant issue. Unlike in the past, concerns about adverse effects have limited the role of opioids in post-operative pain management. This study aims to compare the effectiveness of intravenous paracetamol and  diclofenac as postoperative analgesia in laparoscopic cholecystectomy. Methods:One hundred and twenty eight patients of American Society of Anesthesiologists (ASA) categories I and II  included in this study  were divided into two groups. Anesthesia induction and maintenance were standardized. The first group received 15mg/kg (maximum 1gm) intravenous paracetamol and the second group received 2mg/kg (maximum 75mg) intravenous diclofenac 30 minutes prior to ending of surgery. A questionnaire was responded by patients and chart was maintained by visual analogue scale. Mann Whitney U test was used to analyze quantitative data and Chi-square test for categorical data. P value <0.05 was considered statistically significant. Results:  Profiles of hemodynamic changes were almost similar in both groups with respect to heart rate and blood pressure. However, paracetamol infusion provided hemodynamic stability in post-operative period. We observed statistically significant differences  in visual analogue scale between the two groups. Most of the patients in paracetamol group had low mean pain scores in post-operative period and provided an extended analgesia compared to diclofenac. No serious postoperative complication was observed in  paracetamol group.   Conclusion: Administration of intravenous paracetamol has better and prolonged analgesic effect  with low mean pain score and less requirement for rescue analgesia compared to diclofenac.

Abstract 359: Unit-Specific Influences on Conscious Sedation Nursing Practices: Comparing Medication Utilization and Patient Outcomes

2020 ◽  
Vol 13 (Suppl_1) ◽  
Author(s):  
Linda Parone ◽  
Sahil Rawal ◽  
Allison Ellis ◽  
Bryant Peterson ◽  
Lourdes Escalante ◽  
...  
Keyword(s):  
Patient Satisfaction ◽  
General Anesthesia ◽  
Clinical Outcomes ◽  
Median Time ◽  
Conscious Sedation ◽  
Adverse Outcomes ◽  
P Value ◽  
Medication Utilization ◽  
American Society ◽  
Cardiac Catherization

Background: Unit-Specific influences may determine the amount of sedation given to patients and lead to deviations in patient satisfaction and clinical outcomes due to vague guidelines (4). This study aims to compare medication utilization, clinical outcomes and patient satisfaction in order to determine safety and efficacy of nurse administrated conscious sedation. Methods: Data from outpatient procedures in Cardiac Catherization Lab (Cath Lab) and Interventional Radiology (IR) departments were collected including comorbidities, labs, procedural characteristics, clinical outcomes, and post-sedation questionnaires. Results: Mean age was 63 ± 14 years and 124 (54.9%) were males. Cath Lab n=132 and IR n=94. Procedure duration(min) was found to be longer in the Cath Lab 55 (37,81), than in IR 24 (16,45), p-value of <0.001. The American Society of Anesthesiologist (ASA) scores of Cath Lab 26(21%), IR 29(30.9%), p-value (0.1). Total amount of versed (mg) given in the Cath Lab 2 (1,2), significantly less than IR 3 (1,4.5) with a p-value of <0.01. Total amount of fentanyl (mcg) for Cath Lab 50(50,100), and IR 100 (50,100) with a p-value of <0.01. Median time between 1 st and 2 nd dose of versed in Cath Lab 0 (0,1), IR 9 (5, 16). Median time between 2 nd and 3 rd dose of versed for Cath Lab 0 (0,0), IR 6 (0,13.5) with a p-value <0.001. Median time between 1 st and 2 nd dose of fentanyl in Cath Lab 1 (0,14.8), IR 12.5 (6.8, 24) with a p-value <0.001. Median time between 2 nd and 3 rd dose of fentanyl for Cath Lab 0 (0,0), IR 0,(0,15), p-value <0.001. Median second dose of versed in Cath Lab 0 (0,1), IR 1 (1,1). Median second dose of fentanyl in Cath Lab 25 0 (0,25), IR 25 (25,50), p-value <0.001. Post-Sedation Questionnaire completed by 57 patients, Cath Lab n=30, IR n=27. Patients that felt uncomfortable during their procedure in Cath Lab 11(36.7%), compared to IR 1 (3.7%). The choice of sedation that patient would choose if undergoing a similar procedure again if under general anesthesia Cath Lab 6(20%), IR 0(0%), p-value 0.03. Patients stated that they would recommend conscious sedation to others based on their previous experience, Cath Lab 24 (80%), IR 27(100%). Conclusion: Patients receiving conscious sedation while undergoing procedures in both the Cath Lab and IR were found to have no adverse outcomes and were considered safe. The procedural duration of catheterization procedures was significantly longer than IR with no adverse outcomes, but patients in the Cath lab received less sedation medication and were found to be less satisfied with their procedure. Patients from Cath Lab received less initial sedation medication and rarely received an additional dose. Cath Lab patients were more likely to not recommended conscious sedation to others (20%), and 6 (20%) stated they would rather undergo a similar procedure under general anesthesia; 36.7% of Cath Lab patients stated that they were uncomfortable during the procedure.

scholarly journals Intubating Conditions with Rocuronium Bromide and Suxamethonium in Elective Surgeries: A Randomized Comparative Study

2019 ◽  
Vol 7 (1) ◽  
pp. 3-8
Author(s):  
Kanchan Prakash Paudyal ◽  
Pawan Puspa Baral ◽  
Laxmi Pathak
Keyword(s):  
Tracheal Intubation ◽  
Comparative Study ◽  
P Value ◽  
Intubation Attempt ◽  
Medical Sciences ◽  
Intubating Conditions ◽  
Airway Trauma ◽  
Group 3 ◽  
American Society ◽  
Lottery System

INTRODUCTION: Adequate  intubating  condition  is  required  to  avoid  airway  trauma  and  adverse  sympathetic  responses. Though, Succinylcholine is considered as ideal drug, it has many contraindications. In search of alternative, rocuronium is found to have similar responses in higher doses. Therefore, our aim was to compare the effect of different dosages of rocuronium with sucinylcholine for tracheal intubation and the haemodynamic variables.  MATERIAL AND METHODS: A prospective randomized comparative study was conducted in Universal College of Medical Sciences (UCMS-TH) in 90 (American Society of Anaesthesiologists Physical Status I and II) patients with age between 18 to 60 years scheduled for elective surgeries under general anesthesia. They were divided into 3 groups of 30 each using lottery system. Groups 1 and 2 received intravenous rocuronium 0.6mg/kg and 1mg/kg respectively whereas patients in group 3 received intravenous succinylcholine 1.5mg/kg. Under continuous monitoring, tracheal intubation attempt was done at 60 seconds after the administration of drug and intubating conditions were assessed according to Cooper et al four point scale.  RESULTS: Only 26.7% of patients in group 1 exhibited excellent intubating condition whereas in groups 2 and 3, excellent intubating condition was exhibited in 100% when muscle relaxant was administered at 60 seconds with highly significant statistical difference between groups 1 and 3 with p value <0.001 without any adverse effects in any of these patients. CONCLUSION: This study concluded that intubating response with inj. succinylcholine 1.5mg/kg is similar to rocuronium 1.0mg/kg and is superior to inj rocuronium 0.6mg/kg, for intubating condition at 60 seconds following the drug administration while using Cooper et al. Score.

scholarly journals Transabdominal Pre-peritoneal Mesh Repair versus Lichtenstein’s Hernioplasty

2017 ◽  
Vol 15 (2) ◽  
pp. 135-140 ◽  
Author(s):  
Rajan Koju ◽  
Ram Bhakta Koju ◽  
Balaram Malla ◽  
Yashad Dongol ◽  
Lok Bikram Thapa
Keyword(s):  
Quality Of Life ◽  
Minimal Invasive ◽  
Laparoscopic Technique ◽  
P Value ◽  
Early Return ◽  
Post Operative Pain ◽  
Study Results ◽  
Ethical Committee Approval ◽  
Duration Of Operation

Background: In the era of minimal invasive surgery, hernia repair has seen a paradigm shift from open to laparoscopic technique. However, superiority of laparoscopic repair over open repair is still controversial. Available literatures have shown laparoscopic technique to be better in term of post-operative pain and early return to work.Methods: In this prospective study, a total of 102 patients aged 21-78 years with inguinal hernia were recruited and enrolled into two comparative groups, namely Lichtenstein’s and Transabdominal pre-peritoneal, and each group containing 51 participants. Hospital ethical committee approval and written informed consent from patients was obtained. Primarily, the duration of operation, post-operative pain and complication, and quality of life after surgery was compared between the two different approaches of hernia repair.Results: The study results demonstrated a statistically significant superiority of trans abdominal pre-peritoneal repair over Lichtenstein’s hernioplasty in terms of post operative pain (2.00±0.63 vs 3.90±0.74 VAS score, P value<0.001), hospital stay (2.33±0.62 vs 2.96±0.20 days, P value <0.001) and quality of life with early return to normal work (13.39±0.60 vs 17.88±0.86 days, P value <0.001); whereas a prolonged operative time was seen in transabdominal pre-peritoneal repair (96.08±27.08 vs 42.55±5.95 mins, P value <0.001). Conclusions: This study has shown that transabdominal pre-peritoneal repair is better than Lichtenstein’s in respect to post-operative pain, quality of life and post-operative complication. However, it has prolonged operative duration than conventional method.

scholarly journals PERBANDINGAN NYERI YANG TERJADI 24 JAM PASCA OPERASI PADA PENDERITA YANG DIBERIKAN ANESTESIA UMUM DAN ANESTESIA SPINAL

e-CliniC ◽  
2015 ◽  
Vol 3 (3) ◽  
Author(s):  
Fiska M. Muhammad ◽  
Lucky Kumaat ◽  
Iddo Posangi
Keyword(s):  
General Anesthesia ◽  
Spinal Anesthesia ◽  
Emotional Experience ◽  
P Value ◽  
Inhalation Anesthesia ◽  
Vas Score ◽  
Post Operative Pain ◽  
Wide Range ◽  
Significant Difference ◽  
Anesthesia Spinal

Abstract: Pain can be described as an unpleasant sensory and emotional experience associated with tissue damage which has already occured or potentially will be occurred. General anesthesia is oftenly perfomed on a wide range of surgical procedures. There are two techniques of general anesthesia: inhalation anesthesia and intravenous anesthesia. Spinal anesthesia is one of the simplest and most reliable of regional anesthesia technique. This study aimed to compare the pain between general anesthesia and spinal anesthesia 24 hours post operative. This was an analytical prospective study. Samples were 24 patients consisting of 12 patients with general anesthesia and 12 patients with spinal anesthesia. The inclusion criteria were patients aged 20-60 years old, duration of operation 1-4 hours, and the operations were caesarean section and hysterectomy. The pain assessment used VAS score as well as blood pressure, pulse, and respiration. Data were statistically analyzed by using the Mann-Whitney test and showed a p-value 0.876. Conclusion: There was no significant difference in 24-hour-post-operative pain using VAS score among patients with general anesthesia and with spinal anesthesia.Keywords: VAS scores, general anesthesia, spinal anesthesia.Abstrak: Nyeri dapat digambarkan sebagai suatu pengalaman sensorik dan emosional yang tidak menyenangkan yang berkaitan dengan kerusakan jaringan yang sudah atau berpotensi terjadi. Anestesia umum sering dilalukan pada berbagai macam prosedur pembedahan dan terbagi atas anestesia inhalasi dan anestesia intravena. Anestesia spinal merupakan salah satu anestesia yang paling sederhana dan paling dapat diandalkan dari tehnik anestesia regional. Penelitian ini bertujuan untuk mengetahui perbandingan nyeri pada pemberian anestesia umum dan anestesia spinal 24 jam pasca operasi. Penelitian ini menggunakan metode analitik prospektif. Terdapat 24 sampel yang terbagi atas 12 penggunaan anestesia umum dan 12 penggunaan anestesia spinal, dengan kriteria rentang umur pasien 20-60 tahun, lama operasi 1-4 jam serta jenis pembedahan seksio sesarea dan histerektomi. Penilaian nyeri menggunakan skor VAS serta tekanan darah, nadi dan respirasi. Data diolah dengan menggunakan program SPSS versi 20. Hasil uji statistik Mann-Whitney mendapatkan nilai p= 0,876 yang menunjukkan tidak terdapat perbedaan bermakna dari skor VAS. 24 jam pasca operasi dengan anestesia umum dan anestesia spinal. Simpulan: Tidak terdapat perbedaan bermakna nyeri 24 jam pasca operaasi dinilai dengan skor VAS pada pemberian anestesia umum dan anestesia spinal.Kata kunci: Skor VAS, anestesia general, anestesia spinal

scholarly journals Open versus primary repair following hemorrhoidectomy for Grade III hemorrhoids: a prospective comparative study

2018 ◽  
Vol 5 (10) ◽  
pp. 3377
Author(s):  
Abdul Ghader Barazandeh Moghadam ◽  
Shoaibuddin Mohammad ◽  
Bushra Khan
Keyword(s):  
Statistical Analysis ◽  
Comparative Study ◽  
Return To Work ◽  
Primary Repair ◽  
Anal Stenosis ◽  
P Value ◽  
Duration Of Surgery ◽  
Prospective Comparative Study ◽  
Open Versus ◽  
Grade Iii

Background: The debate on open versus primary closure following haemorrhoidectomy continues to be active.  Despite other methods like doppler guided haemorrhoidal artery ligation, sclerotherapy, cryotherapy, banding; open haemorrhoidectomy is performed at many places. The never-ending discussion on the better choice between open versus primary repair led to the initiation of this work.Methods: This is a prospective comparative study of a contiguous and continuous cohort of 105 cases. Alternate cases were assigned for either of the procedures. Only grade III haemorrhoids were included. Grade I and II haemorrhoids, cases treated earlier and recurrent haemorrhoids were excluded. Multiple parameters like duration of surgery, intraoperative and post-operative bleeding, pain duration and severity, time taken to return to work, use of dressings and sitz bath, wound healing time and stenosis were studied. A blinded statistical analysis was done by a third-party statistician. Results: Primary haemorrhoidectomy took a significantly longer time (P value- 0.0043). Pain was significantly less with open haemorrhoidecomy (P value- 0.0023). Post-operative pain was significant in primary repair. Pain was assessed using visual analogue scale and verbal rating scale. Open haemorrhoidectomy took a significantly longer time to heal (P value: 0.0004) and return to work (P value: 0.0001). Primary repair had stenosis requiring dilatation in a few cases. Statistical analysis was done in all cases. Conclusions: Primary repair seems to be preferred because of shorter duration of recovery despite more pain and occasional anal stenosis.

scholarly journals Single-layer versus double-layer intestinal anastomosis: A comparative study

2017 ◽  
Vol 13 (2) ◽  
pp. 134-143 ◽  
Author(s):  
Tuhin Shah ◽  
RK Agarwal ◽  
RK Gupta ◽  
CS Agrawal ◽  
S Khaniya
Keyword(s):  
Comparative Study ◽  
Double Layer ◽  
Intestinal Anastomosis ◽  
Single Layer ◽  
P Value ◽  
Layer Versus ◽  
Elective Setting ◽  
Prospective Comparative Study ◽  
Layer Groups ◽  
Mean Time

Background: Intestinal anastomosis is essential to maintain the continuity after resection. There has been constant controversy due to various repair options. Adequate apposition can be achieved by either single- or double-layer anastomosis which may affect the post-operative outcome.Objective: To compare the outcome of single-layer versus double-layer anastomosis of small and large intestine.Method: This prospective comparative study was conducted over a period of 16 months, and included 78 patients who underwent intestinal anastomosis (without diverting stoma) after fulfilling inclusion and exclusion criteria. They were randomized into double-layer and single-layer intestinal anastomosis groups by a computer generated series. Double layer anastomosis was constructed using inner continuous Polyglactin 3-0 and outer interrupted Silk 3-0, while single layer anastomosis was done with interrupted PDS 2-0.Result: The mean age was 39.79±17.78 years. A total of 59% were operated in emergency room while 41% in elective setting. Overall mean time for anastomosis was 31.81±6.03 (21-50) minutes. In double- and single-layer intestinal anastomosis mean time was 34.35±5.80 (26-50) and 29.13±5.08 (21-45) minutes respectively, which was statistically significant (p value < 0.05). Single-layer was completed 5 minutes earlier than double layer anastomosis in average. Clinical anastomotic leak was seen in six (7.7%) patients, three in each group. Eight (10.3%) patients had surgical site infection: 3 in double-layer and 5 in single-layer groups. One (1.3%) mortality was seen, from single-layer anastomosis group.Conclusion: Single-layer anastomosis can be constructed in significantly shorter time with similar complication rate when compared to doublelayer anastomosis.Health Renaissance 2015;13(2): 134-143

scholarly journals Laparoscopic versus open appendectomy: a prospective comparative study

2017 ◽  
Vol 18 (2) ◽  
pp. 29-32
Author(s):  
Sumita Pradhan ◽  
Yagya Ratna Shakya ◽  
Hemant Batajoo ◽  
Balram Malla ◽  
Hem Nath Joshi ◽  
...  
Keyword(s):  
Laparoscopic Appendectomy ◽  
Operative Time ◽  
Open Appendectomy ◽  
P Value ◽  
Alvarado Score ◽  
Post Operative Pain ◽  
Prospective Comparative Study ◽  
A Prospective Study ◽  
Laparoscopic Versus Open Appendectomy

Introduction: Appendectomy is one of the most commonly performed surgeries usually done by conventional open method. The role of laparoscopic appendectomy is still not well defined in the literature and although widely practiced it still hasn’t gained popularity in Nepal. The aim of this study was to compare the outcomes of laparoscopic versus open appendectomy.Methods: A prospective study was carried out, between August 2013 and September 2014, involving 216 patients (93 males and 123 females) with a diagnosis of acute appendicitis based on Alvarado score of seven and above. Patients were allocated into two groups where every alternate patient was operated either open or laparoscopically. The groups were compared in terms of operative time, post operative pain, post operative complications and length of hospital stay.Results: Open appendectomy (OA) comprised of 106 patients and Laparoscopic appendectomy (LA) comprised of 110 patients. Patients’ characteristics were similar in both groups. The mean operative time in LA was 42.82±10.84 minutes and in OA 37.99±9.81 minutes (p<0.86). Conversion was done in 2.8% of laparoscopic cases. Mean comparison of postoperative pain by visual analogue scale was low in LA compared to OA (P<0.05). Mean post operative stay (3.19±1.26 vs 2.75±0.7, p<0.01) and surgical site infection was recorded in 9 patients (8.5%) in OA group and 3 (2.5%) in LA group, with p value of 0.06.Conclusions: Laparoscopic appendectomy is feasible and safe as open procedure with less post operative pain and shorter hospital stay. Journal of Society of Surgeons of Nepal, 2015; 18 (2), page: 29-32

scholarly journals Comparative Study of Infiltration of Lidocaine with Adrenaline versus Sterile Water in Type 1 Tympanoplasty Performed under General Anaesthesia

2018 ◽  
Vol 26 (3) ◽  
pp. 213-218
Author(s):  
Santosh Uttarkar Pandurangarao ◽  
Sridurga Janarthanan
Keyword(s):  
Pain Relief ◽  
Comparative Study ◽  
General Anaesthesia ◽  
Tertiary Care ◽  
P Value ◽  
Sterile Water ◽  
Tertiary Care Centre ◽  
Type 1 Tympanoplasty ◽  
Post Operative Pain

Introduction It is a common practice to infiltrate 2% lignocaine with 1:2,00,000 adrenaline for Type 1 Tympanoplasty, even when the surgery is done under general anaesthesia. The purpose of this study is to evaluate the necessity of infiltration of lidocaine with adrenaline (2% lidocaine with 1:2,00,000 adrenaline) in Type 1 Tympanoplasty surgeries performed under general anaesthesia in terms of per-operative bleeding and post-operative pain relief.   Materials and Methods A double blinded, prospective randomized comparative study was conducted in a tertiary care centre. A total of 50 patients planned for Type 1 Tympanoplasty under general anaesthesia, for chronic otitis media, inactive, mucosal disease were selected and divided into two groups randomly. Group A (25 patients) received local infiltration of 2% Lidocaine with 1:2,00,000 adrenaline and Group B (25 patients) patients received infiltration of sterile water. The per -operative bleeding and post-operative pain relief were assessedat 2nd, 4th and 6th post-operative hour in both the groups and the results were analysed.   Results P value for per operative bleeding was <0.77 (non-significant). And the P value for post-operative pain relief at 2nd hour was <0.002 (significant). But the P value for 4th (<0.133) and 6th (<0.358) post-operative hours were not significant.   Conclusion Infiltration of 2% lidocaine with 1:2,00,000 adrenaline, doesn’t have any significant impact in per-operative bleeding and post-operative pain relief at 4th and 6th hour. But there is a significant pain relief, for 2 hours after surgery, when 2% lidocaine with 1:2,00,000 adrenaline is used for infiltration.

scholarly journals Reliable and Rapid Smooth Extubation After "Ketamine-Propfol Mixture" for Induction of General Anesthesia in Laparoscopic Drilling of Polycystic Ovary: A Randomized, Double-Blind, Comparative Study

2021 ◽  
Vol In Press (In Press) ◽  
Author(s):  
Atef Mohammad Khalil ◽  
Joseph Makram Botros ◽  
Maged Labib Boules ◽  
Safaa Gaber Ragab
Keyword(s):  
Comparative Study ◽  
General Anesthesia ◽  
Polycystic Ovary ◽  
Sedation Score ◽  
Controlled Study ◽  
Physical Status ◽  
Double Blind ◽  
Airway Response ◽  
American Society ◽  
American Society Of Anesthesiologists

Background: Ketofol's effect on hemodynamics and the airway response during inducing general anesthesia has been studied previously. However, ketofol's effect on the smoothness of extubation has not been studied yet. Objectives: We aimed to assess ketofol’s effect on the smoothness of extubation and compare it with propofol for inducing general anesthesia. Methods: This double-blind, randomized, and controlled study was conducted on 106 class I and II female patients with the “American Society of Anesthesiologists Physical Status (ASAPS),” aged 18 - 40 years, scheduled for laparoscopic drilling for polycystic ovary disease under general anesthesia. The patients were assigned to two groups of 53 patients each: Group KP = ketofol and Group P = propofol. Results: There was an excellent sedation score during suction and extubation in the ketofol group. The airway response and smoothness of extubation were better in the ketofol group than in the propofol group. Conclusions: Ketofol as an induction anesthetic agent more effectively attenuated the airway response during extubation than only propofol.

Sign in / Sign up

Export Citation Format

Share Document