scholarly journals Clinical and epidemiological features of acute intestinal infections caused by opportunistic enterobacteria in young children

Author(s):  
Г.А. Харченко ◽  
О.Г. Кимирилова

Установлены клинико-эпидемиологические особенности острых кишечных инфекций (ОКИ), вызванных условно-патогенными энтеробактериями (УПЭ) у детей раннего возраста, в зависимости от этиологического фактора. Источниками информации являлись данные Управления Роспотребнадзора по Астраханской области (АО), медицинская документация (720 историй болезни) пациентов в возрасте до 1 года, лечившихся в ГБУЗ ОИКБ им. А. М. Ничоги, Астрахань, с января 2019 по декабрь 2020 г. включительно. ОКИ, вызванные УПЭ у детей в АО, составляют 74%, в том числе у детей в возрасте до 1 года – 60% от общего количества больных ОКИ уточненной бактериальной этиологии. Независимо от этиологического фактора ОКИ, вызванные УПЭ, протекали в виде моноинфекции (83%) средней степени тяжести (62%). Симптомы интоксикации имели прямую корреляционную связь (r = от 0,52 до 0,76; p < 0,001) с выраженностью диарейного синдрома и дегидратации. С уменьшением возраста ребенка увеличивалась продолжительность купирования этих симптомов (r = -0,72; p < 0,001). Clinical and epidemiological features of acute intestinal infections (AKI) caused by opportunistic enterobacteria (UPE) in young children, depending on the etiological factor were established. The information sources were the data of Rospotrebnadzor Administration in the Astrakhan oblast (AO), medical documentation (720 case histories) of patients under the age of 1 year treated in GBUZ «Regional clinical infectious hospital named. A. M. Nichogi» Astrakhan from January 2000 through December 2020. AKI caused by UPE in children in AO is 74%, including 60% in children under 1 year of age, of the total number of patients with AKI of specified bacterial etiology. Regardless of the etiological factor, AKI caused by UPE occurred in the form of monoinfection (83%), moderate severity (62%). Symptoms of intoxication had a direct correlation (r = 0,52 to 0,76; p < 0.001) with the severity of diarrheal syndrome and dehydration. With a decrease in the age of the child, the duration of relief of these symptoms increased (r = -0,72; p < 0,001).

2018 ◽  
Vol 17 (3) ◽  
pp. 27-33 ◽  
Author(s):  
O. V. Molochkova ◽  
O. B. Kovalev ◽  
A. L. Rossina ◽  
O. V. Shamsheva ◽  
A. A. Korsunsky ◽  
...  

A retrospective analysis of the etiological structure and clinical manifestations of acute intestinal infections was conducted in 8459  children hospitalized in a specialized infectious disease department at the Children's City Clinical Hospital No.9 in Moscow,  in 2015—2017 based on the study of statistical reports of the Children's City Clinical Hospital No.9 for 2015—2017 and 2417 case histories of children aged 1 month to 18 years old.It was found that children with age 1—7 years of age (58.5%) are more likely to have acute intestinal infections and are hospitalized. The etiological interpretation of acute intestinal infections remains at a low level and is 28.6%. The leading causative agents of acute intestinal infections are viruses (83%), mainly rotaviruses (62%), less often noroviruses (18%). Topical diagnosis in the vast majority of patients with acute intestinal infections was gastroenteritis (74.7%), which leads to the development of toxicosis with exsiccosis,  especially in young children, which is the reason for hospitalization  in the hospital. The share of bacterial diarrhea is small (17%), among them salmonella  is significant, and in young children  — staphylococcal infection. In recent years, the relevance of identifying campylobacter and clostridium, these pathogens may be the cause of the development of diarrhea with hemoccolitis.


2009 ◽  
Vol 62 (9-10) ◽  
pp. 461-467
Author(s):  
Ljiljana Nesic ◽  
Predrag Canovic ◽  
Zeljko Mijailovic ◽  
Jelena Djokovic

Introduction. Although well protected, brain is not resistant to infection agents. Acute infections of our nervous system appear more often in children and in persons who have medical history data about previous disorders, especially disorders of the nervous system. It is difficult to list possible risk factors which can be responsible for the appearance of infections of CNS and the resulting conditions. It is often difficult or impossible to determine what previous neural damage was (trauma, anoxic damages etc.) from those appearing during infections of CNS. All-inclusive anamnestic research reduces the possibility of approximate judgments. Material and methods. The research was based on the retrospective analysis of medical documentation of 275 patients. All patients were divided into three groups according to the final diagnosis. The first group consisted of 125 patients who were treated for acute virus encephalitis, the second group consisted of 125 patients who were treated for acute bacterial meningoencephalitis and the third group consisted of 25 patients who were treated for cerebritis. Discussion. In our studies sample, the youngest patient was 3 years old and the oldest was 87 years old. The highest number of patients with virus infection of the CNS was in the group under 25 years of age (45.6%). The highest number of patients with bacterial infections of the CNS and cerebritis was in the group of patients over 45 years of age (64%, 37%). Conclusion. Risk factors were more present in bacterial infections of the nervous system and cerebrit thanin virus infection of CNS. In virus infections of the CNS, 28% of patients had some risk factor, most often-chronic ethylism, diabetes mellitus and acquired heart diseases. In bacterial infections of the CNS, 64% of patients had some predisposed factor. The most frequent factor of risk in these patients were chronic otitis (21.6%) and craniotrauma (14.4%). In cerebritis, risk factors were present in 76% of patients and they were: sepsis (20%), chronic otitis (12%) and systemic lupus erythematosus (8%).


PEDIATRICS ◽  
1949 ◽  
Vol 4 (3) ◽  
pp. 342-348
Author(s):  
JOHN C. JONES ◽  
DONALD B. EFFLER

A brief review of the literature referring to intrathoracic nerve tumors in children is presented. The neurogenic tumors have an expected incidence of malignancy of about 40%. Four case histories are reported in which neurogenic tumors of the posterior mediastinum were removed with apparent cure. Only one of these children had objective or subjective signs which could be attributed to their neoplasms. All of the neoplasms were benign. Prompt thoracotomy is advocated in the child with a suspected neurogenic tumor of the mediastinum. Periods of observation, procrastination and roentgen therapy are to be condemned for it is impossible to predict with any degree of certainty which tumor will or already has undergone malignant changes. A brief discussion of the operative management and complications is presented.


1982 ◽  
Vol 63 (6) ◽  
pp. 57-58
Author(s):  
N. A. Romanova ◽  
R. M. Khasanova

The aim of the work was to study the dynamics of serum immunoglobulins in children of the first three years of life, patients with salmonellosis, coli infection and dysentery. Of 129 children, 58 had salmonellosis typhimurium, 39 had coli infection caused by Escherichia of the 1st category, 32 had dysentery Sonne. Among patients with salmonellosis, 7 had a mild form, 44 had a moderate form, and 7 had a severe form. 16, among the most severe - in 19, severe - in 4 children. With dysentery, a mild form was observed in 13 children, a moderate form in 19. Children from 6 months to 1 year old were 69, from a year to 3 years old - 60.


2019 ◽  
Vol 5 (11) ◽  
pp. 104-114
Author(s):  
A. Beregovoi ◽  
Z. Dzholbunova ◽  
R. Kadyrova

The clinical and epidemiological features of the course of acute bacterial meningitis in various age groups of patients in the period from 2014 to 2018 are described. An analysis of 398 case histories of patients was performed. Patients were divided into 5 age groups. The inclusion criterion is the presence of bacterial meningitis of any etiology. Patients with serious meningitis of viral and tuberculous etiology were excluded. Statistical processing was carried out using the SPSS program (determination of compliance with Gauss law, descriptive statistics, determination of average values, relationships between disease indicators, Bonferroni correction). Risk factors were determined, the course of neuro infection in various age groups was revealed, the criteria and the timing of the diagnosis of meningitis.


2016 ◽  
Vol 21 (5) ◽  
pp. 290-295
Author(s):  
Zarema G. Tagirova ◽  
D. R Akhmedov ◽  
N. M.-G Zulpukarova ◽  
Z. M Daniyalbecova

There were studied epidemiological features of the prevalence rate of acute intestinal infections (AII) in the Republic of Dagestan (RD). The prevalence rate of acute intestinal infections in RD was shown to correspond taken as a whole, to Russian indices, however, the regional feature is the high prevalence rate of shigellosis, there is remained a high proportion of the AII of unidentified etiology. There was substantiated the necessity of development and implementation of targeted programmes aimed at the decline in the morbidity rate in problematic territories. The solution to the problem of the AII in the Republic is possible only under the coordination of efforts of federal and local authorities, sanitary - epidemiological and medical institutions.


PEDIATRICS ◽  
1978 ◽  
Vol 61 (1) ◽  
pp. 144-145
Author(s):  
Hania W. Ris

I read with great interest the timely article by Drs. Auman and Waldenberg, "Gonococcal Periappendicitis and Salpingitis in a Prepubertal Girl" (Pediatrics 58:287, August 1976), which deals with the important problem of Neisseria gonorrhoeae as an etiological factor of vaginitis and its complications in a 5-year-old girl. Vaginal discharge and penile discharge in young children, irrespective of age, should be cultured in appropriate media for N. gonorrhoeae in addition to those for other organisms. According to Kotcher et al.,1 the gonococcus was the only significant bacterial etiological agent in 57 cases of vulvovaginitis in prepubertal girls.


Author(s):  
Mari De Beer ◽  
Alts Kritzinger ◽  
Ursula Zsilavcz

The aim of the article is to describe the communication profiles of five young children with fetal alcohol spectrum disorder (FASD) from 4 to 58months of age. A collective case-study design following a quantitative and descriptive approach was used to describe the communication profilesof the participants. The results are described according to the participants’ case histories and a four-level early communication assessment framework.The significant findings were that all participants were in foster care, and presented with incomplete case histories, general developmentaldelays and delays regarding all aspects of their communication abilities. An increase in the severity of the spectrum disorder across the participants’combined communication profiles was also identified. Participants presented with complex multiple neurodevelopmental needs thatshould be viewed within a developmental systems and ecological framework. The importance of early identification, diagnosis and assessmentof infants and young children prenatally exposed to alcohol, the identification of precursors to communication impairment at a very early age,and the need for individualised early communication intervention to improve developmental outcomes within a family-centred approach arediscussed. Suggestions for future research to accumulate knowledge about FASD in the field of early communication intervention are made.


Author(s):  
Gloria B. Roldán Urgoiti ◽  
Amitabh D. Singh ◽  
Roger Y. Tsang ◽  
Robert A. Nordal ◽  
Gerald Lim ◽  
...  

AbstractBackground: Ependymomas are rare tumors of the central nervous system whose management is controversial. This population-based study of adults and children with ependymoma aims to (1) identify clinical and treatment-related factors that impact survival and (2) determine if postoperative radiotherapy (RT) can improve survival of patients with subtotal resection (STR) to levels similar to patients who had gross total resection (GTR). Methods: This retrospective population-based study evaluated 158 patients with ependymoma diagnosed between 1975-2007 in Alberta, Canada. Results: Younger patients (<7 years of age) were more likely to be diagnosed with grade III tumors compared with adults in whom grade I tumors were more common (p=0.003). Adults were more likely to have spinally located tumors compared to young children whose tumors were typically found in the brain. Overall, young children with ependymoma were more likely to die than older children or adults (p=0.001). An equivalent number of patients underwent GTR as compared with STR (48% vs 45%, respectively). Overall, older age, spinal tumor location, lower grade, and GTR were associated with improved progression free survival but only GTR was associated with significant improvement in overall survival. Median survival after STR and RT was 82 months compared with 122 months in patients who had GTR (p=0.0022). Conclusions: This is the first Canadian population-based analysis of patients with ependymoma including adults and children. Extent of resection appears to be the most important factor determining overall survival. Importantly, the addition of RT to patients initially treated with STR does not improve survival to levels similar to patients receiving GTR.


2020 ◽  
Vol 12 (2) ◽  
pp. 113-118
Author(s):  
N. V. Gonchar ◽  
I. V. Razd`yakonova ◽  
N. V. Skripchenko ◽  
S. G. Grigor’ev

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