First Report of the WMO COVID-19 Task Team on Meteorological and Air Quality (MAQ) factors affecting the COVID-19 pandemic.

Author(s):  
Judy Omumbo

<div> <div> <div> <div> <div> <div> <div> <div> <div> <div>The World Meteorological Organization (WMO) Research Board has set up an interdisciplinary and international Task Team to respond to the challenge of providing timely decision support and relevant knowledge on Meteorological and Air Quality (MAQ) factors affecting the SARS-CoV-2/COVID-19 pandemic. The Task Team aims to provide decision makers and the public with a rapid summary of the state of knowledge regarding potential MAQ influences on SARS-CoV-2/COVID-19; to offer general technical guidance for researchers and service providers who wish to consider MAQ data in their analyses, estimates, predictions and projections of COVID-19 risks. The work of the task  motivated both by the global relevance of the subject and by the staggering number of papers and pre-prints currently available, which emphasizes the need for careful review and communication of the state of the science. This first  report presents a summary of key findings of the review to date, as informed by peer reviewed literature.</div> <p> </p> <div>A key finding is that the underlying mechanisms that drive seasonality of respiratory viral infections are not yet well understood. To date, COVID-19 transmission dynamics appear to have been controlled primarily by government interventions rather than meteorological factors. Respiratory viral infections frequently exhibit some form of seasonality, particularly in temperate climates and some evidence from laboratory studies of SARS-CoV-2, suggests that the virus survives longer under cold, dry, and low ultraviolet radiation conditions. There is also evidence that chronic and short-term exposure to air pollution exacerbates symptoms and increases mortality rates for some respiratory diseases and this is consistent with early studies of COVID-19 mortality rates. However, there is no direct, peer reviewed evidence of pollution impacts on the transmission of SARS-CoV-2 at this time. Process-based modeling studies anticipate that COVID-19 transmission may become seasonal over time, suggesting Meteorology and Air Quality (MAQ) factors may support monitoring and forecasting of COVID-19 in the coming months and years.</div> <p> </p> <div>Additional research quantifying links between MAQ factors and COVID-19 is needed.</div> </div> </div> </div> </div> </div> </div> </div> </div> </div>

2017 ◽  
Vol 16 (5) ◽  
pp. 80-86
Author(s):  
E. I. Burtseva ◽  
E. A. Mukasheva ◽  
A. G. Rosatkevich

This paper presents the risk analysis of influenza virus infection in different age groups based on the prevalence and mortality rates. The epidemiological characteristics of the influenza virus circulation during postpandemic period are given. Main aspects of specific and non-specific influenza prevention are discussed. The efficacy of the interferon-based medication Grippferon in the prevention of influenza and acute respiratory viral infections (ARVI) is justified.


2021 ◽  
Vol 7 (1) ◽  
pp. 36-41
Author(s):  
O. P. Balitska ◽  
Yu. M. Hryhoruk ◽  
M. A. Artemchuk ◽  
V. S. Zlahoda V. S.

Acute respiratory viral infections (ARI) and influenza occupy a leading place in the structure of the overall morbidity of the population in most countries. Aim. To assess the rational prescription of drugs for etiotropic therapy of ARI in the outpatient practice. Materials and methods. The following materials for research were used: case histories; treatment sheets; the Unified clinical protocol of primary care for adults and children “Acute respiratory infections”; data of the State Formulary of Medicines as of January 2021; the Register of wholesale prices; the weekly “Apteka” (Pharmacy). The methods of retrospective, descriptive, frequency, and VEN-analysis were applied. Results. According to the research results, using patient histories, it was found that family doctors prescribed 67 drugs by trade names. For etiotropic therapy, 24 drugs were used; it was 37 % of the total number, and 63 % – for symptomatic therapy. Such drugs as Amizon, Aflubin, Amixin, Resistol, Umkalor were for etiotropic therapy (more than 5 prescriptions). None of these drugs is included in the State Formulary of Medicines and the Unified clinical protocol for the treatment of influenza and SARS. Thus, these drugs are without the proven efficiency, safety and cost-effective use. Conclusions. The study conducted has shown that the drugs prescribed most often do not have an evidence base of efficacy and safety; none of the most frequently prescribed drugs is included in the State Formulary of Medicines and the Unified clinical protocol. A direct relationship between an increase in the number of prescriptions and an increase in price has been proven. Key words: acute respiratory viral infections; influenza; frequency analysis; VEN-analysis; family doctor.


Viruses ◽  
2018 ◽  
Vol 10 (12) ◽  
pp. 682 ◽  
Author(s):  
Mingyuan Han ◽  
Charu Rajput ◽  
Tomoko Ishikawa ◽  
Caitlin Jarman ◽  
Julie Lee ◽  
...  

Respiratory viral infections are strongly associated with asthma exacerbations. Rhinovirus is most frequently-detected pathogen; followed by respiratory syncytial virus; metapneumovirus; parainfluenza virus; enterovirus and coronavirus. In addition; viral infection; in combination with genetics; allergen exposure; microbiome and other pathogens; may play a role in asthma development. In particular; asthma development has been linked to wheezing-associated respiratory viral infections in early life. To understand underlying mechanisms of viral-induced airways disease; investigators have studied respiratory viral infections in small animals. This report reviews animal models of human respiratory viral infection employing mice; rats; guinea pigs; hamsters and ferrets. Investigators have modeled asthma exacerbations by infecting mice with allergic airways disease. Asthma development has been modeled by administration of virus to immature animals. Small animal models of respiratory viral infection will identify cell and molecular targets for the treatment of asthma.


2019 ◽  
Vol 72 (3) ◽  
pp. 405-408 ◽  
Author(s):  
Nataliia O. Gevkaliuk ◽  
Nataliya I. Sydliaruk ◽  
Larysa Ya. Posolenyk ◽  
Oksana Ya. Vydoinyk ◽  
Lesia I. Kuchyrka

Introduction: The clinical course of acute respiratory viral infections was not sufficiently studied, specially the state of oxidative homeostasis in children with influenza stomatitis. This fact became the base for our study. The aim: to characterize the state of oxidative-prooxidant system as one of the factors of non-specific resistance of children` organism with influenza stomatitis. Materials and methods: A survey was conducted on 384 children with acute respiratory viral infections aged from 6 months to 12 years, among them 318 had lesions of oral cavity. The mild form was diagnosed in 52 children, moderately severe - in 185, severe - in 81 children. The control group consisted of children without lesions of oral cavity (66 people). To analyze lipid peroxidation we used a spectrophotometric determination of diene conjugates. The ceruloplasmin activity and the transferrin saturation in blood plasma by iron were determined by G. Babenko’s method. Results: We found the intensification of lipid peroxidation: a significant increase of diene conjugates in serum up to 13.78 %, the level of which depended on the severity of disease. We also found the activity increase of ceruloplasmin in 1,8 times in patients with severe course of disease. The saturation of blood plasma transferrin by iron was significantly reduced - for 15.27 % in patients with severe course of influenza stomatitis. Conclusions: Changes in antioxidant system happend due to the activation of lipid peroxidation, and because of the inability to neutralize toxic metabolites in the children` body the intoxication syndrome developed.


2015 ◽  
Vol 13 (2) ◽  
pp. 39-45
Author(s):  
T.N. Malyugina ◽  
◽  
N.V. Malinina ◽  
E.V. Mikhaylova ◽  
◽  
...  

2011 ◽  
Vol 31 (4) ◽  
pp. 341-356 ◽  
Author(s):  
Virginia Amanatidou ◽  
Apostolos Zaravinos ◽  
Stavros Apostolakis ◽  
Demetrios A. Spandidos

2017 ◽  
Vol 96 (4) ◽  
pp. 22-27 ◽  
Author(s):  
I. V. Babachenko ◽  
◽  
L. A. Alekseeva ◽  
O. M. Ibragimova ◽  
Т. V. Bessonova ◽  
...  

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