scholarly journals Final-response form for the Editor

2020 ◽  
Author(s):  
chen chen
Keyword(s):  
Response Form ◽  
Final Response

Echo answers in native/non-native interaction

Pragmatics ◽  
2003 ◽  
Vol 13 (2) ◽  
pp. 285-309 ◽  
Author(s):  
Jan Svennevig
Keyword(s):  
Native Speakers ◽  
The Other ◽  
Epistemic Authority ◽  
Response Word ◽  
Institutional Interaction ◽  
Response Form ◽  
Response Formats ◽  
Final Response ◽  
Different Response

An echo answer is an answer that repeats elements of the question. This response form occurs after yes/noquestions and “statements about B-events”. The current study is based on data from native/non-native institutional interaction, and echo answers are shown to play an important role in certain types of repair that are characteristic of such interaction. Echo answers have two main usages. The first is to appropriate a candidate formulation and integrate it into one’s own turn in progress. This often happens when native speakers attempt to assist non-native interlocutors in expressing themselves. The other is to claim a strengthened commitment to the answer. This is especially salient in cases where a minimal agreement might project a potential dispreferred response. Echo answers may occur alone or with an initial or final response word, and these different response formats are shown to index the relative epistemic authority of the interlocutors.

scholarly journals Interfacing aptamers, nanoparticles and graphene in a hierarchical structure for highly selective detection of biomolecules in OECT devices

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Carlotta Peruzzi ◽  
Silvia Battistoni ◽  
Daniela Montesarchio ◽  
Matteo Cocuzza ◽  
Simone Luigi Marasso ◽  
...  
Keyword(s):  
Biomedical Applications ◽  
Au Nanoparticles ◽  
Limit Of Detection ◽  
High Sensitivity ◽  
Minimal Invasiveness ◽  
Hierarchic Structure ◽  
Final Response ◽  
Detection Of Biomolecules ◽  
Good Signal ◽  
Detection Of Biomarkers

AbstractIn several biomedical applications, the detection of biomarkers demands high sensitivity, selectivity and easy-to-use devices. Organic electrochemical transistors (OECTs) represent a promising class of devices combining a minimal invasiveness and good signal transduction. However, OECTs lack of intrinsic selectivity that should be implemented by specific approaches to make them well suitable for biomedical applications. Here, we report on a biosensor in which selectivity and a high sensitivity are achieved by interfacing, in an OECT architecture, a novel gate electrode based on aptamers, Au nanoparticles and graphene hierarchically organized to optimize the final response. The fabricated biosensor performs state of the art limit of detection monitoring biomolecules, such as thrombin-with a limit of detection in the picomolar range (≤ 5 pM) and a very good selectivity even in presence of supraphysiological concentrations of Bovine Serum Albumin (BSA-1mM). These accomplishments are the final result of the gate hierarchic structure that reduces sterich indrance that could contrast the recognition events and minimizes false positive, because of the low affinity of graphene towards the physiological environment. Since our approach can be easily applied to a large variety of different biomarkers, we envisage a relevant potential for a large series of different biomedical applications.

scholarly journals THE FINAL RESPONSE OF THE SMALL CUTANEOUS VESSELS

1929 ◽  
Vol 50 (4) ◽  
pp. 489-512 ◽  
Author(s):  
Peyton Rous ◽  
H. P. Gilding
Keyword(s):  
Human Skin ◽  
Maximum Pressure ◽  
Arterial Blood ◽  
Final Response

A study of the blanchings (Bier's spots) which develop in human skin deprived of circulation has proved them referable to the same general causes that lead to ischemic patching of the skin of animals, and that they are conditioned by the same factors. Both are expressions of a secondary contraction of vessels that have become hyperirritable owing to an inadequate circulation. The contraction is favored by emptying the vessels, but it occurs pronouncedly even when there is a trickle through them of arterial blood. In the case of man the contractile impulse is sometimes so great as to overcome the maximum pressure that the vessels will support. The significance of the observations is discussed.

Subspecialization Within Pediatric Practice: A Broader Spectrum

PEDIATRICS ◽  
1992 ◽  
Vol 90 (4) ◽  
pp. 573-581 ◽  
Author(s):  
Brian W. McCrindle ◽  
Barbara Starfield ◽  
Catherine DeAngelis
Keyword(s):  
United States ◽  
Primary Care ◽  
Response Rate ◽  
Fellowship Program ◽  
Pediatric Practice ◽  
Ongoing Controversy ◽  
Manpower Supply ◽  
Final Response ◽  
Pediatric Subspecialty ◽  
Final Response Rate

This study was undertaken to describe subspecialty characteristics and practices of the population of pediatricians given the ongoing controversy regarding a projected manpower oversupply of general pediatricians. A questionnaire was mailed to a national random sample of 1620 United States physicians listed in the American Medical Association's Pysician Masterfile as being in office-based pediatric practice. The final response rate was 63%. Seventy percent of respondents designated their practices as "general pediatrics" versus 17% as "general pediatrics with a specific subspecialty interest" and 13% as "subspecialty practice." The general pediatricians with a specific subspecialty interest were intermediate in the proportion that had some training in a pediatric fellowship program (general pediatricians with a specific subspecialty interest, 63% versus general pediatricians, 14%, P < .0001, and pediatricians with a subspecialty practice, 92%, P < .0001) and that were certified in a pediatric subspecialty by the American Board of Pediatrics (general pediatricians with a specific subspecialty interest 16% versus general pediatricians, 2%, P < .0001, and pediatricians with subspecialty practice, 62%, P < .0001). They were also intermediate in the proportion involved in various academic pursuits. Their practices, however, more closely resembled general pediatricians than pediatricians with a subspeciality practice in their location, setting, associates, and commitment to primary care. They were more likely than general pediatricians to utilize or provide specialized tests or procedures. A large percentage of pediatricians incorporate subspecilaty elements into their general pediatric practices. Models of current and projected pediatric manpower supply need to be reassessed in light of this form of practice.

Rapid-responding carbon dioxide and oxygen electrodes

1964 ◽  
Vol 19 (3) ◽  
pp. 550-553 ◽  
Author(s):  
Irving Fatt
Keyword(s):  
Carbon Dioxide ◽  
Gas Phase ◽  
Filter Paper ◽  
Oxygen Electrode ◽  
Membrane Material ◽  
Millipore Filter ◽  
Oxygen Electrodes ◽  
Final Response ◽  
Pco2 Measurement ◽  
Po2 Measurement

Redesign of the Severinghaus pCO2 and the Clark pO2 electrodes yields electrodes which are easier to make and assemble. When used with a new membrane material, paraffin-treated Millipore filter paper, the redesigned Severinghaus pCO2 electrode gives 99% response in 15 sec for a 40 mm Hg change in pCO2 in the region of 15–60 mm Hg pCO2 in either gas or water phase. The redesigned Clark pO2 electrode when used with treated Millipore paper gives 99% of final response in 1.24 sec for a 155 mm Hg change of pO2 in the gas phase in the range 0–160 mm Hg pO2. In aqueous solutions this electrode gives 99% response in 30 sec. Severinghaus electrode; polarographic oxygen electrode; pCO2 measurement; pO2 measurement Submitted on March 19, 1963

Using an Interrupted Behavior Chain Strategy to Teach Generalized Communication Responses

1986 ◽  
Vol 11 (3) ◽  
pp. 196-204 ◽  
Author(s):  
Pam Hunt ◽  
Lori Goetz ◽  
Morgen Alwell ◽  
Wayne Sailor
Keyword(s):  
Severe Disabilities ◽  
Communicative Function ◽  
Response Form ◽  
Behavior Chain ◽  
Students With Severe Disabilities ◽  
Behavior Chains ◽  
Selection Of

Three students with severe disabilities were taught to request items or events within four interrupted behavior chain contexts. When interrupted behavior chain procedures were in effect, a typical operant instructional trial for teaching communication responses was inserted into the middle of an ongoing predictable sequence of behaviors such as brushing teeth or playing ball. Throughout the baseline and intervention phases, generalization probes were conducted to determine whether the newly acquired responses would be performed within behavior chains not yet used for instruction. The results demonstrated that for each of the three students the communicative function and the response form acquired within one behavior chain context generalized without further instruction to at least two chains in which training had not yet occurred. Moreover, for two of the students the picture discrimination skills required for selection of the appropriate content for each communication response generalized to nontraining contexts.

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