Production of curcumin-loaded lipid nanocarriers and assessment of its qualitative characteristic

The article discusses methods for calculating the loss ratio of insurance companies, including compulsory medical insurance, which is the basis for building a health system; suciency of formed reserves, which are created in connection with the possibility of losses. Variants of interpretation of calculated indicators into a qualitative characteristic of the insurance company. A comparative analysis of the calculation of indicators of loss-making of insurance companies and the adequacy of the formation of reserves of insurance companies according to Russian accounting standards and in accordance with the requirements of international financial reporting standards.

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Surface Modified Nanoparticulate Carriers for the Targeted Treatment of Breast Cancer

International Journal of Pharmaceutical Sciences and Nanotechnology ◽

10.37285/ijpsn.2015.8.1.2 ◽

2015 ◽

Vol 8 (1) ◽

pp. 2698-2714

Author(s):

Neeraj Mishra ◽

Tejinder Singh ◽

Nidhi ◽

Supandeep Singh Hallan ◽

Veerpal Kaur

Keyword(s):

Breast Cancer ◽

Tumor Targeting ◽

Lipid Nanoparticles ◽

Targeted Treatment ◽

Therapeutic Effects ◽

Target Drug Delivery ◽

Target Drug ◽

Therapeutic Outcomes ◽

Lipid Nanocarriers ◽

Surface Modified

Breast cancer left overs one of the greatest common metastasis disease in females. Advanced diagnostic devices and better understanding of tumour biology can extend the better therapeutic outcomes. Nanotechnology is a tool that helps in cancer diagnosis and treatment therapy. Many nanocarriers such as solid lipid nanoparticles, magnetic nanoparticles, nanocrystals, nanogels, nano-lipid nanocarriers, biodegradable nanoparticles, liposomes, and dendrimers are introduced to improve the therapeutic efficacy of antineoplastic agents. Surface modified target drug delivery system has the potential to increase the therapeutic effects and also reduce the cytotoxicity of breast cancer. Different approaches have been explored for treatment of breast cancer. This review describes the recent advances in the development of nanocarriers used for the targeted treatment of breast cancer. It also focuses on etiology, risk factor and conventional therapy of breast cancer. KEYWORDS: Breast Cancer; Nano-carriers; Tumor Targeting; Ligands; Receptor.

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Lipid-based Nanoplatforms in Cancer Therapy: Recent Advances and Applications

Current Cancer Drug Targets ◽

10.2174/1568009620666200115160805 ◽

2020 ◽

Vol 20 (4) ◽

pp. 271-287 ◽

Cited By ~ 2

Author(s):

Kuldeep Rajpoot

Keyword(s):

Drug Delivery ◽

Cancer Therapy ◽

Adverse Effects ◽

Targeted Drug Delivery ◽

Tumor Therapy ◽

Cancer Therapies ◽

Medication Delivery ◽

Lipid Nanocarriers ◽

Targeted Drug ◽

Drug Nanocarriers

Though modern available cancer therapies are effective, they possess major adverse effects, causing non-compliance to patients. Furthermore, the majority of the polymeric-based medication platforms are certainly not universally acceptable, due to their several restrictions. With this juxtaposition, lipid-based medication delivery systems have appeared as promising drug nanocarriers to replace the majority of the polymer-based products because they are in a position to reverse polymer as well as, drug-associated restrictions. Furthermore, the amalgamation of the basic principle of nanotechnology in designing lipid nanocarriers, which are the latest form of lipid carriers, has tremendous chemotherapeutic possibilities as tumor-targeted drug-delivery pertaining to tumor therapy. Apart from this, it is reported that nearly 40% of the modern medication entities are lipophilic. Moreover, research continues to be efficient in attaining a significant understanding of the absorption and bioavailability of the developed lipids systems.

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