scholarly journals Long-term exposure to electric fields. A cross-sectional epidemiologic investigation of occupationally exposed workers in high-voltage substations.

1979 ◽  
Vol 5 (2) ◽  
pp. 115-125 ◽  
Author(s):  
Bengt Knave ◽  
Francesco Gamberale ◽  
Sven Bergström ◽  
Elisabeth Birke ◽  
Anders Iregren ◽  
...  
2016 ◽  
Vol 4 (2) ◽  
pp. 307-311 ◽  
Author(s):  
Safia Beshir ◽  
Khadiga Salah Ibrahim ◽  
Weam Shaheen ◽  
Eman M. Shahy

BACKGROUND: Nickel exposure is recognized as an endocrine disruptor because of its adverse effects on reproduction.AIM: This study was designed to investigate the possible testiculo-hormonal perturbations on workers occupationally exposed to nickel and to assess its effects on human male sexual function. METHODS: Cross-sectional comparative study, comprising 105 electroplating male non-smoker, non-alcoholic workers exposed to soluble nickel and 60 controls was done. Serum luteinizing hormone, follicle stimulating hormone, testosterone levels and urinary nickel concentrations were determined for the studied groups. RESULTS: Serum luteinizing hormone, follicle stimulating hormone, urinary nickel and the simultaneous incidence of more than one sexual disorder were significantly higher in the exposed workers compared to controls. The occurrence of various types of sexual disorders (decreased libido, impotence and premature ejaculation) in the exposed workers was 9.5, 5.1 and 4.4 folds respectively than the controls.CONCLUSIONS: Exposure to nickel produces possible testiculo-hormonal perturbations in those exposed workers.


2020 ◽  
Vol 10 (21) ◽  
pp. 7706 ◽  
Author(s):  
Francesco Chirico ◽  
Egeria Scoditti ◽  
Carlo Viora ◽  
Nicola Magnavita

Occupational exposure to elemental mercury still represents a significant risk in the workplace. The sensitivity of the exposed subjects varies considerably. This study aims to summarize the literature on the role of genetic factors in occupationally exposed cohorts. A systematic search of the literature was carried out on PubMed Central (PMC), MEDLINE, and Google Scholar databases in accordance with the “Preferred Reporting Items for Systematic reviews and Meta-Analyses” (PRISMA) guidelines, from 1946 to July 2020. Ten cross-sectional studies were included in the review. All studies referred to the polymorphisms that can favour some neurotoxic effects of the metal in occupational cohorts. Some genetic variants may be associated with an increase in the occupational effects of mercury. Given the limited evidence, genetic screening of all mercury-exposed workers is not recommended. However, a personalized search for polymorphisms could be taken into consideration if exposed workers report early neurotoxic symptoms.


2008 ◽  
Vol 27 (9) ◽  
pp. 709-713 ◽  
Author(s):  
M Baranska ◽  
L Van Amelsvoort ◽  
S Birindelli ◽  
S Fustinoni ◽  
E Corsini ◽  
...  

We performed a cross-sectional study involving workers from four European countries in which exposure to pesticides and immune parameters were evaluated over a short period of time. The total study population consisted of 238 workers occupationally exposed to pesticides and 198 nonoccupationally exposed workers. The study showed that pesticide exposure at levels encountered by workers under different conditions in Europe did not affect the ability of the immune system to respond to vaccination. We could, however, identify individuals within the group of pesticide exposed workers who were genetically characterized by the 2.2 IL-1α polymorphism and who showed a lower antibody response, pointing out the importance of the understanding of genetic variability and the interaction between genetic and environmental factors in the identification of high-risk individuals, which may eventually lead to preventive measures.


2007 ◽  
Vol 58 (2) ◽  
pp. 211-221 ◽  
Author(s):  
Jordan Minov ◽  
Jovanka Karadžinska-Bislimovska ◽  
Kristin Vasilevska ◽  
Snžana Risteska-Kuc ◽  
Sašo Stoleski

Occupational Asthma in Subjects Occupationally Exposed to Herbal and Fruit Tea DustWe performed a cross-sectional study to detect occupational asthma (OA) in 63 subjects occupationally exposed to herbal and fruit tea dust and in 63 corresponding controls. The evaluation included a questionnaire, skin prick tests to workplace and common inhalant allergens, spirometry, and histamine challenge test. The evaluation of the work-relatedness of asthma in the exposed workers was based on serial peak expiratory flow rate (PEFR) measurements and bronchoprovocation tests. We found a higher prevalence of respiratory symptoms in the exposed workers, whereas spirometric parameters were significantly lower. The prevalence of sensitisation to allergens and of bronchial hyperresponsivenss (BHR) did not differ significantly between the groups. The prevalence of asthma was also similar in both groups (8.0 % vs. 6.4 %; P=0.540). Work-relatedness of symptoms was reported by all asthmatic tea workers and by no control with asthma. Significant work-related changes in PEFR diurnal variations and in non-specific BHR, suggesting allergic OA, were found in one tea worker with asthma (1.6 %). No specific workplace agent causing OA in the affected subject was identified. None of the tea workers with asthma met the criteria for medical case definition of the reactive airway dysfunction syndrome (RADS). Our data confirm workplace exposure to herbal and fruit tea dust as a risk factor for OA.


2002 ◽  
Vol 18 (3) ◽  
pp. 229-241 ◽  
Author(s):  
Kurt A. Heller ◽  
Ralph Reimann

Summary In this paper, conceptual and methodological problems of school program evaluation are discussed. The data were collected in conjunction with a 10 year cross-sectional/longitudinal investigation with partial inclusion of control groups. The experiences and conclusions resulting from this long-term study are revealing not only from the vantage point of the scientific evaluation of new scholastic models, but are also valuable for program evaluation studies in general, particularly in the field of gifted education.


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