Hardware and Software Complex for Detection and Visualization of Subsurface Blood Vessels During Brain Tumors Resection

2021 ◽  
Vol 91 (3) ◽  
pp. 55-66
Author(s):  
A. M. Udeneev
Keyword(s):  
Brain Tumor ◽  
Brain Tumors ◽  
Blood Vessel ◽  
Blood Vessels ◽  
Endoscopic Resection ◽  
Near Infrared ◽  
Bovine Brain ◽  
Infrared Light ◽  
Near Infrared Light ◽  
Different Depths

Purpose: The purpose of this work is to prove the possibility of subsurface blood vessels detection during endoscopic resection of brain tumors using the method of endoscopy in red and near infrared light. Material and methods: This work was accomplished with an experimental setup, simulating the geometry of endoscopic resection of brain tumor. The setup realizes the backlight of operational field with light from diagnostic window of electromagnetic spectrum (650 1000 nm) and takes photos of operational field. After that special algorithm increases the contrast of the photos and detect subsurface blood vessels. The pieces of bovine brain have served as brain samples. And thin-walled transparent plastic tube with an internal diameter 1 mm filled with bovine blood has served as a blood vessel. The tube was placed into brain samples on different depths. Results: During the experiments the series of photos of bovine brain with artificial blood vessels located on different depths was received. For every photo contrast was increased and blood vessel was recognized. Conclusion: The series of experiments has showed the possibility to detect the blood vessels with outer diameter 1 mm in the depth of 2 mm and 3 mm in brain tissues using the method of endoscopy in red and near infrared light. The depth of 3 mm is enough for preliminary detection of blood vessel during the endoscopic resection of brain tumor.

The use of near-infrared light for safe and effective visualization of subsurface blood vessels to facilitate blood withdrawal in children

2013 ◽  
Vol 35 (4) ◽  
pp. 433-440 ◽  
Author(s):  
Natascha J. Cuper ◽  
John H.G. Klaessens ◽  
Joris E.N. Jaspers ◽  
Rowland de Roode ◽  
Herke Jan Noordmans ◽  
...  
Keyword(s):  
Blood Vessels ◽  
Near Infrared ◽  
Infrared Light ◽  
Near Infrared Light ◽  
Blood Withdrawal ◽  
Effective Visualization

Development of blood vessel searching system using near-infrared light stereo method for clinical blood sampling

2014 ◽  
Author(s):  
Kai Cheng ◽  
Yusuke Morita ◽  
Eiji Nakamachi ◽  
Norihiro Honda ◽  
Kunio Awazu
Keyword(s):  
Blood Vessel ◽  
Near Infrared ◽  
Blood Sampling ◽  
Infrared Light ◽  
Near Infrared Light

scholarly journals Depth estimation of the absorbing structure in a slab turbid medium using point spread function

2020 ◽  
Vol 3 (SI3) ◽  
pp. First
Author(s):  
Ngoc An Dang Nguyen ◽  
To Ni Phan Van ◽  
Kohei Yamamoto ◽  
Minh Quang Nguyen ◽  
Anh Tu Tran ◽  
...  
Keyword(s):  
Blood Vessel ◽  
Point Spread Function ◽  
Near Infrared ◽  
Fluorescent Imaging ◽  
Turbid Medium ◽  
New Technique ◽  
Infrared Light ◽  
Near Infrared Light ◽  
Point Spread ◽  
Spread Function

Nowadays, transillumination imaging is more popular used in the medical field with the development of the vein finder and the non-invasive diagnosis applications. Near-infrared light with a wavelength of 700 - 1200 nm has relatively high transmission through biological tissue. Using near-infrared light, we can able to obtain a two dimensional (2D) transillumination image of the internal absorption structure such as blood vessel structure, liver ... in the body noninvasively. Even with a simple system (light-emitting diode (LED)'s array and low-cost camera), we could obtain the blood vessel transillumination image of human arm. However, the image is severely blurred due to the strong scattering in the tissue. We have devised the depth-dependent point spread function (PSF) to suppress the scattering effect in fluorescent imaging. In previous studies, we successfully applied this principle and developed a technique to reconstruct the absorbing structure in a turbid medium without using fluorescent material. The feasibility and effectiveness of the proposed technique were verified in experiments. However, this point spread function (PSF) is depth dependence, so that the depth information is required in practice. In order to make this method more practical, the new techniques for estimating the parameters of absorbing structure (depth and width) in the turbid medium by convolution and de-convolution with the point spread function (PSF) were devised. This paper presents a new technique for the estimation depth of an absorber in 2D transillumination image. This new technique was developed to estimate the depth of the absorber in turbid medium by convolution operation with the point spread function (PSF). By observing images with two-wavelength selected at which the scattering property of the medium is different. The transillumination image at one of the wavelengths is convolved with the PSF of another wavelength. Two images of alternative wavelengths are compared while changing the depth of the PSF. We can obtain the correct depth that gives a minimum difference between the two convoluted images. This technique does not require the repetition of the unstable deconvolution operation. The effectiveness of the proposed technique was verified in simulation and experiment.

An ordered copper nanowell-array film with near-perfect broadband absorption from ultraviolet to near-infrared light

2020 ◽  
Vol 59 (11) ◽  
pp. 110906
Author(s):  
Juan Shen ◽  
Yong Ren ◽  
Xinxin Zhu ◽  
Min Mao ◽  
Quan Zhou ◽  
...  
Keyword(s):  
Near Infrared ◽  
Infrared Light ◽  
Near Infrared Light ◽  
Broadband Absorption

scholarly journals Recent Near-Infrared Light-Activated Nanomedicine toward Precision Cancer Therapy

2021 ◽  
Author(s):  
Xiaowei Luan ◽  
Yongchun Pan ◽  
Yanfeng Gao ◽  
Yujun Song
Keyword(s):  
Cancer Therapy ◽  
Near Infrared ◽  
Infrared Light ◽  
Human Society ◽  
Near Infrared Light ◽  
History Of ◽  
The Universe

Light has witnessed the history of mankind and even the universe. It is of great significances to the life of human society, contributing to energy, agriculture, communication, and much more....

scholarly journals Au–ZnO Conjugated Black Phosphorus as a Near-Infrared Light-Triggering and Recurrence-Suppressing Nanoantibiotic Platform against Staphylococcus aureus

Pharmaceutics ◽  
2021 ◽  
Vol 13 (1) ◽  
pp. 52
Author(s):  
Atanu Naskar ◽  
Sohee Lee ◽  
Kwang-sun Kim
Keyword(s):  
Staphylococcus Aureus ◽  
Bacterial Infections ◽  
Near Infrared ◽  
Au Nanoparticles ◽  
Synthesis Method ◽  
Antibacterial Properties ◽  
Black Phosphorus ◽  
Infrared Light ◽  
Resistant Bacteria ◽  
Near Infrared Light

Antibiotic therapy is the gold standard for bacterial infections treatment. However, the rapid increase in multidrug-resistant (MDR) bacterial infections and its recent use for secondary bacterial infections in many COVID-19 patients has considerably weakened its treatment efficacy. These shortcomings motivated researchers to develop new antibacterial materials, such as nanoparticle-based antibacterial platform with the ability to increase the chances of killing MDR strains and prevent their drug resistance. Herein, we report a new black phosphorus (BP)-based non-damaging near-infrared light-responsive platform conjugated with ZnO and Au nanoparticles as a synergistic antibacterial agent against Staphylococcus aureus species. First, BP nanosheets containing Au nanoparticles were assembled in situ with the ZnO nanoparticles prepared by a low-temperature solution synthesis method. Subsequently, the antibacterial activities of the resulting Au–ZnO–BP nanocomposite against the non-resistant, methicillin-resistant, and erythromycin-resistant S. aureus species were determined, after its photothermal efficacy was assessed. The synthesized nanocomposite exhibited excellent anti-S. aureus activity and good photothermal characteristics. The non-resistant S. aureus species did not produce drug-resistant bacteria after the treatment of multiple consecutive passages under the pressure of the proposed nanoantibiotic, but rapidly developed resistance to erythromycin. This work clearly demonstrates the excellent photothermal antibacterial properties of Au–ZnO–BP nanocomposite against the MDR S. aureus species.

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