FEATURES OF PAIN SYNDROME IN THE LUMBAR REGION AMID INFLAMMATORY GYNECOLOGICAL DISEASES

Vestnik ◽  
2021 ◽  
pp. 9-13
Author(s):  
А.М. Жукембаева ◽  
Г.Д. Жаманбай ◽  
А.М. Барат ◽  
С.Т. Дюсенгалиева ◽  
У.Г. Шакиманова ◽  
...  
Keyword(s):  
Lumbar Spine ◽  
Inflammatory Diseases ◽  
Pain Syndrome ◽  
Lumbar Region ◽  
Clinical Symptomatology ◽  
Lower Back ◽  
Gynecological Diseases ◽  
Continue Research ◽  
Pathological Focus ◽  
The Impact

Проведен анализ особенностей развития болевого синдрома в нижних отделах спины, в проекции поясничного отдела позвоночника на фоне неспецифических воспалительных заболеваний придатков матки (НВЗПМ) у 148 женщин, находившихся на амбулаторном лечении в гинекологическом отделении поликлиники №5 г. Алматы в 2019-2020 г.г. Установлено, что у 79 (53,4±4,1%) из них отмечался болевой синдром в нижней части спины и сопутствующие ему скованность и ограничение подвижности поясничного отдела позвоночника на фоне обострения НВЗПМ.Критериями для анализа являлись динамика клинической симптоматики НВЗПМ и болевого синдрома с учетом его локализации на фоне проводимого лечения. При этом было проведено сравнение результатов, зафиксированных при поступлении и через 14 суток после начала лечения НВЗПМ. Перспективным представляется продолжить исследования и оценить влияние спинально-генитального рефлекса на течение первичного патологического очага в придатках матки. The development of the features of pain syndrome in the lower back, in the projection of the lumbar spine amid nonspecific inflammatory diseases of the uterine appendages (NIDUA) in 148 women who were on outpatient treatment in the gynecological department of polyclinic # 5 in Almaty in 2019-2020 were analized. It was found that 79 (53.4 ± 4.1%) of them had pain in the lower back and concomitant stiffness and limitation of the mobility of the lumbar spine amid exacerbation of NIDUA. The analysis criteria were the dynamics of the clinical symptomatology of NIDUA and pain syndrome, taking into account its localization amid treatment. At the same time, a comparison was made between the results recorded at admission and 14 days after the start of the NIDUA treatment. It seems promising to continue research and assess the impact of the spinal-genital reflex on the course of the primary pathological focus in the uterine appendages.

DISORDERS OF PERIPHERAL CIRCULATION AMID CHRONIC OSTEOCHONDROSIS OF THE LUMBAR SPINE

Vestnik ◽  
2021 ◽  
pp. 24-28
Author(s):  
Р.С. Бегимбетова ◽  
Н.О. Бейсембинова ◽  
А.К. Кадырали ◽  
Г.М. Жолдасова ◽  
А. Бауржанкызы ◽  
...  
Keyword(s):  
Lumbar Spine ◽  
Informed Consent ◽  
Clinical Symptoms ◽  
Personal Data ◽  
Pain Syndrome ◽  
Peripheral Circulation ◽  
Research Protocol ◽  
Initial Visit ◽  
Continue Research ◽  
Inhibitory Reflex

Проведен анализ состояния периферического кровообращения у 28 мужчин, больных остеохондрозом поясничного отдела позвоночника, сопровождающегося люмбалгией с клинической симптоматикой нарушения периферического кровообращения нижних конечностей. Все больные, принимавшие участие в нашем исследовании, подписали информированное согласие на участие в программе и соглашение о неразглашении личных данных и протокола исследований. Критериями для анализа являлись изменения клинической симптоматики остеохондроза поясничного отдела позвоночника, обусловленной им люмбалгии и показателей оксиметрического исследования, которые были зафиксированы при первичном обращении и через 7 суток на фоне проводимого лечения и регрессии болевого синдрома. Таким образом, полученные результаты свидетельствовали о рефлекторном нарушении периферического кровообращения за счет развития патологического спинально-вазального тормозного рефлекса, обусловленного люмбалгией, которые восстанавливаются на фоне регрессии патологической импульсации в поясничном отделе позвоночника. Целесообразно продолжить исследования в этом направлении. The state of peripheral circulation in 28 men were analyzed, patients with osteochondrosis of the lumbar spine, accompanied by lumbodynia with clinical symptoms of impaired peripheral circulation of the lower extremities was carried out. All patients who took part in our study signed an informed consent to participate in the program and a non-disclosure agreement of personal data and research protocol. The criteria for the analysis were clinical symptoms of osteochondrosis of the lumbar spine caused by lumbodynia and indicators of oximetry studies, which were recorded during the initial visit and after 7 days amid treatment and regression of pain syndrome. Thus, the results indicated a reflex disorder of the peripheral circulation due to the development of a pathological spinal-vasal inhibitory reflex caused by lumbodynia, which is restored amid regression of pathological impulses in the lumbar spine. It is advisable to continue research in this direction.

Gynecological diseases in children and adolescents with the acute abdomen syndrome

2021 ◽  
Vol 24 (6) ◽  
pp. 377-382
Author(s):  
I. S. Schneider ◽  
N. A. Tsap
Keyword(s):  
Acute Appendicitis ◽  
Acute Abdomen ◽  
Clinical Symptoms ◽  
Inflammatory Diseases ◽  
Reproductive Function ◽  
Pain Syndrome ◽  
Differential Diagnostics ◽  
Surgical Department ◽  
Gynecological Diseases ◽  
Cause Of Pain

Objective. The differential diagnostics of gynecological diseases with a picture of acute abdomen and acute appendicitis may be challenging and can cause a variety of complications, impaired reproductive function and infertility.Purpose. To assess outcomes after diagnosing and treating girls with the syndrome of “acute abdomen” in whom an acute gynecological pathology was revealed.Material and methods. Case histories of 85 girls with gynecological diseases who were hospitalized to the emergency surgical department of Children City Clinical Hospital No 9 in Yekaterinburg are analyzed. All children were admitted to the emergency department with a picture of “acute abdomen”.Results. All children were operated on laparoscopically, and the cause of their acute abdominal syndrome was clarified. Acute inflammatory diseases of the uterine adnexa prevailed in the structure of causes (59%). In 21% of cases, there was uterine adnexa torsion . The rest of children had apoplexy (11%) and ovarian cysts (9%).Conclusion. The differential diagnostics of acute appendicitis and acute gynecological pathologies is difficult due to various and similar clinical symptoms. Laparoscopy can not only identify the cause of pain syndrome, but also can help to chose a future curative tactics .

scholarly journals Pathogenetic effects of antibiotic resistance on a woman’s reproductive health

2020 ◽  
pp. 66-68
Author(s):  
О.V. Hryshchenko
Keyword(s):  
Inflammatory Diseases ◽  
Topical Therapy ◽  
Chronic Pelvic Pain Syndrome ◽  
Pain Syndrome ◽  
Pelvic Pain Syndrome ◽  
Vaginal Infections ◽  
Urogenital Infections ◽  
Increased Risk ◽  
Gynecological Diseases ◽  
Anti Inflammatory

Background. Over the last decade, women in many countries around the world have seen an increase in the number of urogenital infections, which occupy the first place in the structure of obstetric and gynecological morbidity. Risk factors for the development of inflammatory diseases include the invasive procedures and irrigations, sexual activity, unreasonable treatment, refusal to restore eubiosis after antimicrobial and antifungal therapy, the presence of intrauterine devices, etc. Objective. To characterize the influence of the spread of antibiotic-resistant pathogens on the course of gynecological diseases. Materials and methods. Analysis of literature data on this issue. Results and discussion. Peculiarities of the vaginal infections course’ nowadays include prevalence of self-treatment, uncontrolled antibiotics (AB) use, the development of AB resistance, and the presence of extragenital pathology. Pelvic inflammatory disease (PID) comprise 75 % of all gynecological diseases. PID cause such complications as chronic pelvic pain syndrome, purulent tubo-ovarian tumors, cervical neoplasia, and infertility. The risk of the latter increases depending on the number of episodes of PID. Principles of PID treatment include comprehensiveness, etiopathogenetic orientation, individualization and recurrence prevention. Antibacterial therapy (ABT), nonsteroidal anti-inflammatory drugs, infusions, transfusions, detoxification therapy, medications aimed at the improvement of hemodynamics and microcirculation, immunotherapy, and topical therapy are used in the treatment of PID. The consequences of irrational ABT include an increase in the resistance of pathogenic flora, disruption of the normal body biocenosis, increased risk of adverse reactions, impaired immune function and increased treatment costs. Macrolides, cephalosporins, fluoroquinolones and aminoglycosides are the main groups of AB used for the systemic ABT in PID. Tobramycin (one of the latter group) is active against 83.4 % of pathogens that cause urogenital infections. Other advantages of tobramycin include synergism with β-lactams and high activity against Pseudomonas aeruginosa – a bacterium with a high and dangerous potential for AB resistance. In turn, fluoroquinolones are active against 94 % of pathogens that cause urogenital infections; they are able to penetrate cell membranes and have a low potential for the formation of AB resistance. The combination of fluoroquinolone levofloxacin with ornidazole (Grandazole, “Yuria-Pharm”) can improve the general condition and reduce pain on the 3rd day of treatment of PID, normalize the temperature, reduce hospital stay. Co-administration of levofloxacin and ornidazole as part of an infusion solution is more rational than their separate use. Such treatment minimizes the risk of allergic reactions and side effects. For local sanitation of vagina and vulva, it is advisable to use decamethoxine (Dekasan, “Yuria-Pharm”) – a basic antiseptic that acts on various types of bacteria, viruses, fungi and protozoa. Additional benefits are anti-inflammatory, desensitizing and antispasmodic action. Decamethoxine also effectively reduces the adhesion of staphylococci and Escherichia coli. One of the main advantages of decamethoxine is the lack of effect on human cells. Conclusions. 1. PID are the most common diseases in the field of obstetrics and gynecology. 2. Care should be taken when choosing a drug for ABT. 3. The combination of levofloxacin and ornidazole can effectively treat PID, reducing the duration of inpatient treatment. 4. For local sanitation of the vagina and vulva, it is advisable to use decamethoxine.

scholarly journals The Consequences of Mechanical Vibration Exposure on the Lower Back of Bus Drivers: A Systematic Review

2021 ◽  
Vol 11 (21) ◽  
pp. 9986
Author(s):  
Hyago Gabriel Oliveira Mendes ◽  
Bianca de Moraes Tomaz ◽  
Ana Carolina Coelho-Oliveira ◽  
Juliana Pessanha de Freitas ◽  
Márcia Cristina Moura-Fernandes ◽  
...  
Keyword(s):  
Systematic Review ◽  
Lumbar Spine ◽  
Mechanical Vibration ◽  
Experimental Studies ◽  
Whole Body ◽  
Vibration Exposure ◽  
Lumbar Region ◽  
Bus Drivers ◽  
Lower Back ◽  
Increased Risk

Professional drivers are exposed to whole-body vibration while driving, which contributes to an increased risk of developing physical problems, such as pain in the lower back. This article aims to review the effects of vibration exposure on bus drivers. Searches were performed on the PubMed, Embase, Web of Science, and Scopus databases. Only full articles of observational and experimental studies that investigated the effects of vibration on bus drivers with consequences in the lumbar region published in English were included. Data on driver demographics, study design, objectives, bus model, seat model, length of exposure to vibration, and outcomes were extracted. Two studies were classified as evidence level III-2 and three studies as level III-3. The methodological quality of the publications presented one with a moderate and four with a serious risk of bias. In all the publications, pain in the lumbar spine was reported. In conclusion, the results of this systematic review suggest that bus drivers are exposed to mechanical vibration in their work routine, and this might be considered a risk factor for the development of pain in the lumbar spine, bearing in mind that the exposure is for long periods.

scholarly journals Ergonomi Duduk yang Benar untuk Mencengah Terjadinya Low Back Pain (LBP) di Kelurahan Mayang Mangurai Kota Jambi

2021 ◽  
Vol 3 (3) ◽  
pp. 287
Author(s):  
Putra Hadi ◽  
Wanti Hasmar
Keyword(s):  
Low Back Pain ◽  
Back Pain ◽  
Community Service ◽  
Pain Syndrome ◽  
Birth Trauma ◽  
Sitting Position ◽  
Low Back ◽  
Lower Back ◽  
Tissue Changes ◽  
The Impact

One of the musculoskeletal disorders that often occurs due to incorrect ergonomics is low back pain. Low back pain (LBP) is a pain syndrome that occurs in the lower back region which is the result of various causes including abnormalities of the spine or spine from birth, trauma, tissue changes, and the influence of gravity. Community service activities will be held in April-June 2021 with discussion methods and delivering materials and leaflets related to the introduction of ergonomics in the correct sitting position in order to reduce the impact of low back pain. This Community Service (PKM) aims to be used as a source of knowledge for recitation mothers at the Nurul Al-Ikhlas mosque. The results of the evaluation through the question and answer were that the study mothers had understood the introduction of ergonomic sitting to prevent LBP

scholarly journals Indicators of Elasticity of the Iliopsoas Muscle in Patients with Pain in the Lower Part of the Back due to the Manifestation of the Benign Joint Hypermobility Syndrome

2020 ◽  
Vol 5 (5) ◽  
pp. 142-147
Author(s):  
V. M. Zhdan ◽  
◽  
I. V. Ivanitskiy ◽  
Khaimenova G. S. ◽  
Yu. A. Ischeikina
Keyword(s):  
Shear Wave ◽  
Pain Syndrome ◽  
Joint Hypermobility ◽  
Iliopsoas Muscle ◽  
Lumbar Region ◽  
Hypermobility Syndrome ◽  
Joint Hypermobility Syndrome ◽  
Benign Joint Hypermobility Syndrome ◽  
Lower Back ◽  
Number Of Patients

Pain in the lower back is a highly urgent problem that leads to a decrease in the quality of life of a large number of patients in the modern world. At the same time, the causes of pain in the lower back are different and their combination has not been sufficiently studied to date. It is known that the presence of benign joint hypermobility syndrome in a patient significantly worsens the course and manifestations of pain in the lower back. One of the components of pain in the lower back is changes in the iliopsoas muscle. This is psoas syndrome. At the same time, the diagnosis of psoas syndrome in practical medicine is complicated by the lack of specific laboratory tests and imaging techniques. The purpose of this work was to study the possibilities of determining the tension of the iliopsoas muscle using shear wave elastometry in patients with pain syndrome in the lower back and the difference between their tensions depending on the presence of benign hypermobility syndrome in patients. Material and methods. We examined 83 patients with lower back pain aged 42.31±1.54 years, 41 were female and 42 were male. To participate in the study, all patients underwent X-ray and ultrasound examination of the hip joints. Patients were excluded from the study in the presence of signs of osteoarthritis. To determine the presence of signs of hypermobility of the joints, we used the criteria of Baiton; the diagnosis was made on condition of obtaining more than 5 points. Among the patients examined by the Bayton criteria, 18 patients were diagnosed with benign joint hypermobility syndrome, among them 13 women and 5 men. As a control group, we selected 15 patients aged 45.6±1.74 years without complaints of pain in the lumbar region of the back and hips and without signs of benign joint hypermobility syndrome. We used shear wave elastometry to determine the stiffness of the distal parts of the lumbosacral muscle. A visual analog scale of pain (from 1 to 10) was used to determine the severity of the pain syndrome. Conclusion. We found that all patients with complaints of pain in the lower back had a significantly higher tension of the iliopsoas muscle in comparison with the group of conditionally healthy patients. The increase in tension had a strong correlation with the severity of pain syndrome according to the data of the visual analogue scale. Indicators of muscle tissue rigidity did not depend on the presence and severity of benign joint hypermobility syndrome

Lumbar periarticular cysts of arcorray joint

2020 ◽  
pp. 47-57
Author(s):  
Anton Yarikov ◽  
Maxim Shpagin ◽  
Iliya Nazmeev ◽  
Sergey Gorelov ◽  
Olga Perlmutter
Keyword(s):  
Minimally Invasive ◽  
Severe Pain ◽  
Pain Syndrome ◽  
Long Term Results ◽  
Lumbar Region ◽  
Results Of Treatment ◽  
Invasive Method ◽  
Facet Syndrome

The immediate and long-term results of treatment of 30 patients with severe pain syndrome of the lumbar region, who underwent operations on denervation of DOS, were studied. The aim of the study was to evaluate the effectiveness of minimally invasive technologies for the treatment of pain in the lumbar region (denervation of DOS), to study the near and distant results of these treatment methods. Denervation DOS is an effective minimally invasive method for the treatment of facet syndrome caused by spondylarthrosis. It allows in the early and distant postoperative periods to significantly reduce the pain syndrome and improve the quality of life of patients.

scholarly journals POS1180 TREATMENT COMPLIANCE OF PATIENTS WITH RHEUMATOID ARTHRITIS DURING THE FIRST WAVE OF THE SARS-CoV-2/COVID-19 PANDEMIC IN PORTUGAL: RESULTS FROM THE COVID IN RA (COVIDRA) SURVEY

2021 ◽  
Vol 80 (Suppl 1) ◽  
pp. 871.2-871
Author(s):  
F. Araujo ◽  
N. Gonçalves ◽  
A. F. Mourão
Keyword(s):  
Rheumatoid Arthritis ◽  
Inflammatory Diseases ◽  
Immunosuppressive Treatment ◽  
Treatment Compliance ◽  
Web Based ◽  
Symptoms Of Depression ◽  
Immune Mediated ◽  
Attending Physician ◽  
The Impact ◽  
E Mail

Background:The outcomes of the infection by the SARS-CoV-2 in patients with immune-mediated inflammatory diseases were largely unknown during the early days of the COVID-19 pandemic. It was hypothesized that these patients were at higher risk of morbidity and mortality due to their inherent immune dysfunction and immunosuppressive therapy. Several rheumatology societies issued recommendations urging patients not to stop their anti-rheumatic treatments.Objectives:To assess treatment compliance of patients with rheumatoid arthritis (RA) during the first wave of the SARS-CoV-2/COVID-19 pandemic in Portugal.Methods:The web-based survey COVIDRA (COVID in RA) was developed to assess the impact of the first wave mandatory confinement in patients with RA focusing on 5 domains: RA symptoms, attitudes towards medication, employment status, physical exercise and mental health. The questionnaire was sent to RA patients through e-mail and social media of the Portuguese Society of Rheumatology and two patient associations; and it was filled locally at two rheumatology centers in Lisbon. Recruitment took place during June and July 2020. Descriptive statistics were generated by the survey software and were afterwards transported and evaluated using appropriate biostatistics software.Results:We obtained 441 valid questionnaires. Most respondents were female (88.4%), caucasian (93.6%), with a mean age of 58 (+/-13) years. The majority (57.6%) had longstanding disease (>10 years) and were treated with csDMARDs (63.2%) and/or bDMARDs/tsDMARDS (23,7%). Only 14% (N=61) discontinued or reduced the dosage or frequency of their RA treatment. Most of these changes were previously planned by the attending physician (27.9%). Only 11 patients (18%) discontinued their immunosuppressive medication out of fear of becoming infected with SARS-CoV-2 (corresponding to 2.5% of total responders). Another 11 patients did so because they had no prescription, couldn’t go to the community/hospital pharmacy or couldn’t afford the medication. Although these numbers preclude any statistical analysis, when compared to patients who persisted on their treatment, those discontinuing due to fear of contagion were younger (56.4 vs 58.5 years), all female (100 vs 86.8%), with long-lasting disease (≥ 11 years) (90.9% vs 57.5%), more frequently treated with bDMARDs (36.4 vs 23.1%) and presenting more symptoms of depression (54.5 vs 49.7%).Conclusion:Most RA patients complied with their treatment during the first wave of the SARS-CoV-2 pandemic in Portugal. Only a minority changed their immunosuppressive treatment due to fear of SARS-CoV-2 infection. Very similar rates of immunosuppressive discontinuation due to fear of contagion were reported by other authors (such as Schmeiser et al, Pineda-sic et al and Fragoulis et al).Disclosure of Interests:Filipe Araujo Speakers bureau: Pfizer, Biogen, Novartis, Menarini, Consultant of: MSD, Nuno Gonçalves: None declared, Ana Filipa Mourão: None declared.

Anemia of Inflammation

Hematology ◽  
2010 ◽  
Vol 2010 (1) ◽  
pp. 276-280 ◽  
Author(s):  
Cindy N. Roy
Keyword(s):  
Inflammatory Diseases ◽  
Underlying Disease ◽  
Comorbid Condition ◽  
Regulatory Pathways ◽  
Hepcidin Expression ◽  
Disease States ◽  
Poor Outcomes ◽  
The Impact ◽  
Inflammatory Insult ◽  
Anemia Of Inflammation

Abstract Inflammation arising from various etiologies, including infection, autoimmune disorders, chronic diseases, and aging, can promote anemia. The anemia of inflammation (AI) is most often normocytic and normochromic and is usually mild. Characteristic changes in systemic iron handling, erythrocyte production, and erythrocyte life span all contribute to AI. The preferred treatment is directed at the underlying disease. However, when the inflammatory insult is intractable, or the cause has not been diagnosed, there are limited options for treatment of AI. Because anemia is a comorbid condition that is associated with poor outcomes in various chronic disease states, understanding its pathogenesis and developing new tools for its treatment should remain a priority. Hepcidin antimicrobial peptide has taken center stage in recent years as a potent modulator of iron availability. As the technology for quantitative hepcidin analysis improves, hepcidin's role in various disease states is also being revealed. Recent insights concerning the regulatory pathways that modify hepcidin expression have identified novel targets for drug development. As the field advances with such therapeutics, the analysis of the impact of normalized hemoglobin on disease outcomes will confirm whether anemia is a reversible independent contributor to the morbidity and mortality associated with inflammatory diseases.

Chondroblastoma of the lumbar spine

2005 ◽  
Vol 2 (5) ◽  
pp. 596-600 ◽  
Author(s):  
Raphaël Vialle ◽  
Antoine Feydy ◽  
Ludovic Rillardon ◽  
Carla Tohme-Noun ◽  
Philippe Anract ◽  
...  
Keyword(s):  
Lumbar Spine ◽  
Local Recurrence ◽  
Osteolytic Lesion ◽  
Radicular Pain ◽  
Appendicular Skeleton ◽  
Lumbar Region ◽  
Content Type ◽  
Anterior Posterior ◽  
Fine Print

✓ Chondroblastoma is a benign cartilaginous neoplasm that generally affects the appendicular skeleton. Twenty-six cases of spinal chondroblastoma have been reported in the past 50 years, only six of which were located in the lumbar region. The authors report two cases involving this exceptional location. In both patients, low-back pain, in the absence of radicular pain, was the presenting symptom. In both cases, plain radiography and computerized tomography scanning revealed an osteolytic lesion surrounded by marginal sclerosis. Magnetic resonance imaging allowed the authors to study the tumor's local extension. Examination of a percutaneous fluoroscopy-guided biopsy sample revealed the following typical histological features of chondroblastoma: chondroid tissue, focally alternating with cellular areas, and no nuclear atypia or pleomorphism. To reduce the risk of local recurrence, vertebrectomy and anterior—posterior fusion were performed in both cases. In one case, a structural lumbar scoliosis was corrected during the posterior procedure. There was no postoperative complication. No recurrence was observed during the 3- to 6-year follow-up period. The surgery-related results were deemed successful. Although exceptional, the diagnosis of chondroblastoma is possible in lesions involving the lumbar spine. Other spinal locations are described in the literature, and frequency of recurrence is stressed. A vertebrectomy is advised to reduce the risk of local recurrence.

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