scholarly journals Association between Framingham risk score and metabolic syndrome in elderly

2016 ◽  
Vol 13 (2) ◽  
Author(s):  
Juliana Mezzomo ◽  
Bruna Cocco Pilar ◽  
Patrícia Maurer ◽  
Vanusa Manfredini ◽  
Graziela Morgana Silva Tavares ◽  
...  
Keyword(s):  
Metabolic Syndrome ◽  
Logistic Regression ◽  
Cardiovascular Risk ◽  
Risk Score ◽  
Framingham Risk Score ◽  
The Elderly ◽  
Abdominal Adiposity ◽  
Chi Square ◽  
Glucose Levels ◽  
Framingham Risk

Metabolic syndrome is a set of factors that can increase the mortality from cardiovascular disease. Thus, knowledge about the prevalence of MS in the elderly is important, since the risk factors tend to increase significantly with age. The aim of this study is analyze the prevalence of metabolic syndrome (MS) among elderly according to the IDF and NCEP criteria and determining its relation to Framingham Risk Score (FRS). Elderly people (60 years old or older) of both genders participated in the study. Volunteers signed a TCLE and were interviewed, as well as physical exams. The biochemical analyzis were performed on an automated analyzer LABTEST, LabMax 240 model with biochemical reagents Labtest brand. For the diagnosis of MS NCEP and IDF criteria were used and cardiovascular risk was estimated by calculating the FRS. Descriptive statistics were performed, chi-square test for ordinal variables and ANOVA or Student-t test for quantitative data. Multivariate analysis was performed by logistic regression (backward conditional method). Differences were considered statistically significant at p ≤ 0.05. The overall prevalence of MS found in the sample following the NCEP and IDF criteria was 55.8% and 60.8%, respectively. No associations were found between gender and diagnostic criteria. Individuals with high+moderate FRS had a higher risk of developing MS compared to those with low FRS. Logistic regression analysis showed an independent association of abdominal adiposity by the IDF criteria (OR 4.8, CI 1.0- 22.1; p = 0.04) and glycemia by NCEP criteria (OR 3.0, CI 1.1-8.4; p = 0.03) with moderate+high FRS. The prevalence of MS was high under both criteria, being more predominant in those patients with moderate+high FRS. Thus, the components of MS abdominal adiposity and glucose levels were associated with increased CRF, indicating that the control of these factors can be decisive in reducing cardiovascular risk in the elderly.

scholarly journals Prospective Evaluation of Cardiovascular, Cardiorespiratory, and Metabolic Risk of German Office Workers in Comparison to International Data

2020 ◽  
Vol 17 (5) ◽  
pp. 1590 ◽  
Author(s):  
Markus Strauss ◽  
Peter Foshag ◽  
Roman Leischik
Keyword(s):  
Risk Factors ◽  
Metabolic Syndrome ◽  
Cardiovascular Risk ◽  
Waist Circumference ◽  
Risk Score ◽  
Framingham Risk Score ◽  
Office Workers ◽  
Metabolic Risk ◽  
High Tendency ◽  
Framingham Risk

Background: Employment in the administrative sector is characterized by prolonged sedentary work, which has been tied to increased morbidity and compromised health. The aim of this study was to determine cardiovascular, cardiorespiratory and metabolic risk parameters of German office workers (OWs) in comparison to OWs from other nations. Material and Methods: A total of 46 male office workers from the North Rhine-Westphalia region (Germany) participated in the survey. Anthropometric measurements, cardiovascular and metabolic risk factors, as well as laboratory parameters were taken. The 10-year cardiovascular risk was calculated by using the Framingham risk score. The diagnosis of metabolic syndrome was based on the criteria of the International Diabetes Federation. Cardiorespiratory status was assessed by exercise spirometry. Results: The analyzed group of OWs demonstrated a high prevalence of preobesity (Body Mass Index 26.4 ± 4 and waist circumference 97.3 ± 11.7 cm) and 58.7% of the OWs showed an abnormally large waist circumference. Cardiovascular risk was correspondingly elevated as compared with other international studies (9.7% ± 9.2%). High risk cardiovascular profiles were detected in 10.7% of the participants and 33% of the OWs in our study group were diagnosed with metabolic syndrome. The oxygen uptake of the OWs was 34.1 ± 8.1 mL/kg−1·min−1. Conclusions: The German OWs show elevated cardiovascular risk assessed using the Framingham risk score and also a high tendency for metabolic syndrome. The OWs need to be made further aware of the cardiovascular risk and resulting health implications. Implementation of health promotion concepts such as corporate sports activities or nutrition courses should be taken into consideration to counteract cardiovascular risk factors and the subsequent development of cardiovascular disease in later life.

The metabolic syndrome is amplified in hypothyroid rheumatoid arthritis patients: a cross-sectional study

2008 ◽  
Vol 69 (01) ◽  
pp. 39-42 ◽  
Author(s):  
H G Raterman ◽  
I C van Eijk ◽  
A E Voskuyl ◽  
M J L Peters ◽  
B A C Dijkmans ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Metabolic Syndrome ◽  
Cardiovascular Risk ◽  
Risk Score ◽  
Framingham Risk Score ◽  
Risk Profile ◽  
Cardiovascular Risk Profile ◽  
Prevalence Odds Ratio ◽  
The Metabolic Syndrome ◽  
Framingham Risk

Objectives:Rheumatoid arthritis (RA) patients are at increased risk of cardiovascular disease (CVD), which is even more pronounced in hypothyroid RA patients. An unfavourable cardiovascular risk profile conferred by a higher prevalence of the metabolic syndrome (MetS) and a higher Framingham risk score might explain this amplified cardiovascular morbidity. This study compared first, MetS (features) and second, the Framingham 10-year CVD risk in RA patients with hypothyroidism compared with euthyroid RA patients.Methods:RA patients participating in the CARRÉ investigation were divided into two groups: hypothyroid and euthyroid RA patients. MetS according to the National Cholesterol Education Program Third Adult Treatment Panel criteria and the Framingham risk score was compared between hypothyroid and non-hypothyroid CVD event-free RA patients.Results:In total, 257 RA patients were included: 236 with RA (91.8%) and 21 with hypothyroid RA (8.2%), respectively. The prevalence of the MetS was significantly higher in hypothyroid RA patients (43%) compared with RA patients (20%). Moreover, female hypothyroid RA patients had a higher Framingham risk score compared with euthyroid RA patients. With RA patients as the reference category, the age and gender-adjusted prevalence odds ratio for the MetS was 3.5 (95% CI 1.3 to 9.1) in hypothyroid RA.Conclusions:Hypothyroid RA patients, particularly female patients, have a more unfavourable cardiovascular risk profile, reflected by an increased prevalence of the MetS and higher Framingham score, than euthyroid RA patients, suggesting a greater need for cardiovascular risk management in these patients to prevent future CVD events.

scholarly journals Clinical significance of increased arterial stiffness associated with atrial fibrillation, according to Framingham risk score

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Goh Eun Chung ◽  
Hyo Eun Park ◽  
Heesun Lee ◽  
Su-Yeon Choi
Keyword(s):  
Atrial Fibrillation ◽  
Cardiovascular Risk ◽  
High Risk ◽  
Arterial Stiffness ◽  
Risk Score ◽  
Framingham Risk Score ◽  
Risk Groups ◽  
The Elderly ◽  
High Cardiovascular Risk ◽  
Framingham Risk

AbstractAtrial fibrillation (AF) is the most common arrhythmia in the elderly. Arterial stiffness may predict the risk of AF, but this relationship has not been fully evaluated. We assessed the association between arterial stiffness and prevalent AF. All subjects who had electrocardiography performed and a cardio-ankle vascular index (CAVI) calculated during a screening examination between 2010 and 2019 were enrolled. To evaluate the association between increased arterial stiffness and AF, we divided the population according to their Framingham risk score (FRS) into low-, intermediate-, and high-risk groups. A total of 8048 subjects were evaluated. The multivariate analysis revealed that increased arterial stiffness was significantly associated with AF prevalence, even after adjusting cardiovascular risk factors [odds ratio (OR) 1.685, 95% confidence interval (CI) 1.908–2.588, p = 0.017]. When we subcategorized the subjects according to their FRS, increased arterial stiffness was significantly associated with AF in the intermediate- and high-risk groups (OR 3.062, 95% CI 1.39-6.740 and OR3.877, 95% CI 1.142-13.167, respectively, BMI adjusted. High arterial stiffness shows a significant association with AF in those with intermediate or high cardiovascular risk, and can be used for further risk stratification of patients.

Novel cardiovascular risk factors in the elderly and their correlation with the Framingham risk score

2008 ◽  
Vol 9 (7) ◽  
pp. 683-687 ◽  
Author(s):  
Meltem Halil ◽  
Bunyamin Yavuz ◽  
Burcu Balam Yavuz ◽  
Mustafa Cankurtaran ◽  
Didem Sener Dede ◽  
...  
Keyword(s):  
Risk Factors ◽  
Cardiovascular Risk ◽  
Cardiovascular Risk Factors ◽  
Risk Score ◽  
Framingham Risk Score ◽  
The Elderly ◽  
Framingham Risk

scholarly journals A Retrospective Exploratory Analysis on Cardiovascular Risk and Cognitive Dysfunction in Multiple Sclerosis

2021 ◽  
Vol 11 (4) ◽  
pp. 502
Author(s):  
Antonio Reia ◽  
Martina Petruzzo ◽  
Fabrizia Falco ◽  
Teresa Costabile ◽  
Matteo Conenna ◽  
...  
Keyword(s):  
Cardiovascular Risk ◽  
Cognitive Function ◽  
Risk Score ◽  
Framingham Risk Score ◽  
Verbal Learning ◽  
Macrovascular Disease ◽  
Cardiovascular Comorbidities ◽  
Cholesterol Levels ◽  
Framingham Risk ◽  
Input Variables

Background. Cardiovascular comorbidities have been associated with cognitive decline in the general population. Objectives. To evaluate the associations between cardiovascular risk and neuropsychological performances in MS. Methods. This is a retrospective study, including 69 MS patients. For all patients, we calculated the Framingham risk score, which provides the 10-year probability of developing macrovascular disease, using age, sex, diabetes, smoking, systolic blood pressure, and cholesterol levels as input variables. Cognitive function was examined with the Brief International Cognitive Assessment for MS (BICAMS), including the Symbol Digit Modalities Test (SDMT), the California Verbal Learning Test-II (CVLT-II), and the Brief Visuospatial Memory Test-Revised (BVMT-R). Results. Each point increase of the Framingham risk score corresponded to 0.21 lower CVLT-II score. Looking at Framingham risk score components, male sex and higher total cholesterol levels corresponded to lower CVLT scores (Coeff = −8.54; 95%CI = −15.51, −1.57; and Coeff = −0.11; 95%CI = −0.20, −0.02, respectively). No associations were found between cardiovascular risk and SDMT or BVMT-R. Conclusions. In our exploratory analyses, cardiovascular risk was associated with verbal learning dysfunction in MS. Lifestyle and pharmacological interventions on cardiovascular risk factors should be considered carefully in the management of MS, given the possible effects on cognitive function.

Cardiovascular risk prediction in the general population with use of suPAR, CRP, and Framingham Risk Score

2013 ◽  
Vol 167 (6) ◽  
pp. 2904-2911 ◽  
Author(s):  
Stig Lyngbæk ◽  
Jacob L. Marott ◽  
Thomas Sehestedt ◽  
Tine W. Hansen ◽  
Michael H. Olsen ◽  
...  
Keyword(s):  
Cardiovascular Risk ◽  
General Population ◽  
Risk Prediction ◽  
Risk Score ◽  
Framingham Risk Score ◽  
Framingham Risk ◽  
Cardiovascular Risk Prediction
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