Comparison of Phenobarbital versus Magnesium Sulphate for Management of Neonate with Birth Asphyxia

2021 ◽  
Vol 15 (8) ◽  
pp. 2145-2147
Author(s):  
Lubna Riaz ◽  
Syed Muhammad Ahmed ◽  
Muhammad Ahmad Zakki ◽  
Neelam Faryad ◽  
Shazia Iram ◽  
...  

Background: Poor breathing effort results in decrease oxygen supply to brain and other organs that lead to birth asphyxia. Phenobarbital and magnesium sulphate are both neuroprotective to asphyxia! injury to brain. Objective: To compare the frequency of neonatal mortality with phenobarbital versus magnesium sulphate in the management of birth asphyxia Study Design: Randomized control trial Place and Duration of Study: Pediatrics Department, Sheikh Zayed Hospital, from 8th March 2020 to 8th September 2020. Methodology: One hundred and two neonates were enrolled. After taking informed consent from parents their demographic data was obtained. Then patients were divided in to two groups; group A treated with Phenobarbital and other group B treated with magnesium sulphate. Results: The mean age of group A neonates was 54.37+14.303 days and in group B 48.40+15.20 days with male to female ratio was 0.7:1. Adverse outcome occurred in 12 (11.54%) patients. Statistically insignificant difference (P=0.122) was found between groups. Conclusion: There is more adverse effects outcome with magnesium sulphate than phenobarbital however the difference was statistically insignificant for management of neonates with birth asphyxia. Keywords: Birth asphyxia, Neonates, Magnesium sulphate (MgS04), Phenobarbital

2017 ◽  
Vol 24 (09) ◽  
pp. 1331-1335
Author(s):  
Khalid Hussain ◽  
Maria Tarique ◽  
Attiq ur Rehman Khan ◽  
Asim Bukhari ◽  
Bilal Akhter ◽  
...  

Objectives: To compare Tamsulosin versus ESWL for lower ureteric stonesexpulsion. Study Design: Randomized controlled trial. Setting: Outpatient Department ofUrology at Services Hospital, Lahore. Period: January 2015 to December 2015. Material& Methods: Total 50 patients were enrolled in study. Patients were divided into 2 groups.In group A, 25 patients received daily oral treatment of 0.4mg Tamsulosin for 28 days, andin group B, 25 patients were treated with ESWL. A stone-free condition, was defined as thecomplete absence of any stone based on plain abdominal X-rays observed and during followupvisits at the time of treatment of stone was noted. Results: The mean age of the patientswere recorded as 33.20±9.23 years. There were 40(80%) males and 10(20%) females with maleto female ratio of 4:1. Out of 50 patients, 16(32%) presented with hematuria, 3(6%) had feverwhile 31(62%) appeared with no complication status. Out of 50 patients, 21(42%) presentedwith expulsion time 08-14 days in which 14(28%) were from tamsulosin group and 07(14%)were from ESWL group, similarly 19(38%) patients appeared with expulsion time of 15-28 daysin which 10(20%) were from tamsulosin group and 09(18%) were from ESWL group. Statisticallythere is insignificant difference between the groups i.e. p-value=0.28 Ns. Conclusion: Thisstudy suggests that the tamsulosin helps in the earlier clearance of stone fragments andreduces the complications as compared to ESWL.


2020 ◽  
Vol 32 (2) ◽  
pp. 126-129
Author(s):  
Jahangir Alam Mazumder ◽  
Md Golam Mustafa ◽  
AHM Delwar ◽  
Shazibur Rashid ◽  
Md Mostafizur Rahaman ◽  
...  

Introduction: After SMR/septoplasty with or without turbinate surgery, it needs to keep apart the septum and turbinates upto their complete healing otherwise there is a chance of adhesion (synechia) formation. To prevent this there are variousprocedures. To place an intranasal splint in one or both sides of the septum is one of them. Nowadays there raised thequestion of whether the splinting is necessary or not. There is no significant difference in result with or without anintranasal splint. Weighing against the co-morbidities the routine use of an intranasal splint can no longer be justified. Materials and Methods: This is a randomized control study of 200 patients of SMR/septoplasty, done for nasal septaldeviation causing symptoms in Cumilla Medical College Hospital in the period of January 2016 to December 2019. Theywere equally divided into two groups, group-A were operated placing an intranasal splint and group-B with no intranasalsplint. They were followed up for 6 weeks to detect any synechia and co-morbidities. Result: The age of our patients wasranged from 13-49 years with a mean age of 22.45 years. The male to female ratio is 1.78:1. Synechia was found in 4% ofthe splinted group and 6 of the nonsplinted groups. Co-morbidities were detected more in the splinted group than that ofnon-splinted. In INS group these were found as follows: pain in the nose, face and head (26%), faint during removal ofnasal splint (6%), nasal obstruction (38%), the anxiety of splint removal in the postoperative period (35%) and vestibulitisdue to persistent irritation by a splint (17%). Conclusion: There is little significant advantage of using intranasal splintroutinely in septal surgery to prevent synechia formation. Medicine Today 2020 Vol.32(2): 126-129


2020 ◽  
Vol 11 (SPL4) ◽  
pp. 1357-1361
Author(s):  
Monika Meshram ◽  
Kiran Khandare

Fistula in ano is tract lined by granulation tissue having internal opening in anal canal and rectum and external opening in the perianal region. The incidence of a fistula-in-ano developing from an anal abscess ranges from 26-38%. The prevalence of non-specific anal fistula has been estimated to be 8.6 to 10/100,000 of the population per year, with a male to female ratio of 8:1.in contemporary sciences Bhagandara  can be correlated with Fistula in Ano. To compare the efficacy of AshwathaKsheer Sutra  and UdumberKsheer Sutra in the management of Bhagandara (Fistula in ano).  The present study is designed as a  Randomized single blind parallel in which 40 patients will be enrolled. Patients will be distributed in two group with 20 patients in each group. In group A AshwathaKsheerSutra and in group B UdumbarKsheerSutra will be changed after 7 days till the cure of fistula. Assessment of the patients will be done on day 1st, 8th, 15th, and 22nd after intervention, follow up will be taken on 29th day.  Results will be drawn from the observations of objective parameters. Conclusion of the study will be drawn on the basis of statistical data calculated from the collected data.


2014 ◽  
Vol 17 (49) ◽  
pp. 123-130
Author(s):  
Heberto Romeo Priego Álvarez

RESUMEN Objetivo: Establecer el grado de conocimiento de los profesionales paramédicos sobre la mercadotecnia sanitaria y determinar sus niveles de aplicabilidad. Material y método: Se efectuó una investigación comparativa en dos poblaciones en estudio residentes en el estado mexicano de Tabasco: Grupo A. personal de enfermería en activo, y Grupo B. egresados de la licenciatura de Nutrición de la DACS-UJAT. El instrumento recolector de datos en ambas poblaciones se aplicó en el año 2008, siendo un cuestionario mixto con tres apartados: 1) datos sociodemográficos, 2) conocimientos sobre mercadotecnia sanitaria, y otro 3) sobre la aplicabilidad de la mercadotecnia en el ejercicio profesional considerando las dimensiones social y comercial, así como su uso a nivel externo e interno. La manipulación y el cálculo de los estimadores de las variables de interés se efectuó con DYANE versión 2 (Diseño y Análisis de Encuestas en Investigación Social y de Mercados) obteniéndose las frecuencias relativas y de significancia estadística mediante la diferencia de os proporciones independientes. Resultados: La mayoría de las enfermeras encuestadas (Grupo A) manifestaron tener conocimientos sobre la mercadotecnia (62%), aunque la consideración favorable de su aplicabilidad en la enfermería tuvo igual porcentaje al de aquellas que no estimaron usarla en su ejercicio profesional (50%); si bien el porcentaje más alto (54%) consideró la mercadotecnia como necesaria en la enfermería, la mayoría de las informantes manifestaron no haberla usado (59%). En el Grupo B, el conocimiento de la mercadotecnia fue aun mayor (86%), la consideración de su aplicabilidad en la nutrición fue igualmente alta (73%) y la consideración de necesaria en la profesión tuvo un porcentaje elevado (81%). La mercadotecnia se asoció a la enfermería preponderantemente con un sentido comercial (81%). El uso mayormente identificado fue hacia los aspectos mercadológicos externos (53%), es decir lo relativo a prestación de servicios a usuarios (pacientes). En el Grupo B la opinión fue inversa, dado que la asociación predominante se dio entre la nutrición con un sentido social (78%), centrándose el uso mercadológico externo en los comensales, siendo significativas la diferencia de proporciones. Conclusiones: El conocimiento sobre la mercadotecnia y su aplicación en el ejercicio profesional de la enfermería tiende a ser limitado en las enfermeras(os) tabasqueños, quienes restringen su empleo solo a mejorar la imagen profesional de los enfermeros y a la venta de servicios (otorgamiento de cuidados privados). En el caso de la nutrición, si bien es cierto que el conocimiento y aplicabilidad profesional de la mercadotecnia es mayormente aceptable, aun no está del todo definido su uso. Las acciones que establece la mercadotecnia para la satisfacción del cliente (comensal), el nutriólogo las aplica de manera empírica como parte implícita de su formación profesional. ABSTRACT Objective: Ascertain the knowledge degree of the paramedical professionals in regard to the health marketing and determine its levels of applicability. Material and method: A comparative research was done in two different groups in the state of Tabasco: Group A: Personnel of nursing in active-duty. Group B: Graduates of Nutrition from DACS-UJAT. In both populations the data questionnaire was applied in 2008. This questionnaire was mixed and it included three sections: 1) socio-demographic data, 2) knowledge on health marketing and 3) marketing applicability in the professional performance considering both the social and commercial dimensions, as well as their use in an external and internal level. The manipulation and the calculation of the estimators related to the variables of interest was done with DYANE version 2 (Design and Analysis of Surveys in Social Investigation and Markets) obtaining both the relative frequencies and those of statistical significance by means of the difference of independent proportions. Results: Most of the nurses who answered the survey (Group A) declared to have knowledge on marketing (62%), although the consideration of applying it in the nursery had the same percentage as those who estimated not to use it in their professional performance (50%). Even though the highest percentage (54%) considered the marketing like necessary in the nursery, most of the informants declared not to have used of it (59%). In Group B, the knowledge of marketing was higher (86%), and the consideration of its applicability in nutrition was also high (73%), as well as the consideration of having it as necessary in this profession (81%).The marketing was associated preponderantly to the nursery with a commercial sense (81%). The main identified use was towards the external marketing aspects (53%), that is, those aspects related to the provision of services to the users (patients). In Group B the opinion was inverse, since the predominant association occurred between the nutrition with a social sense (78%), where the centered of the external marketing use is in the companions at table, becoming significant the difference of proportions. Conclusions: The knowledge on marketing and its application on the professional praxis of nursery tend to be limited in the nurses of Tabasco, who restrict its use just to improve their professional image and the sale of services (granting private care). In the case of the nutrition professionals, it is known that the knowledge and professional applicability of marketing are mainly acceptable; however their use is not absolutely defined. The nutritionist applies actions established by marketing in order to satisfy the customer (people at the table to have a meal) in an empirical way as an implicit part of his/her professional formation.


2021 ◽  
Vol 15 (11) ◽  
pp. 3022-3025
Author(s):  
Usman Ahmed ◽  
Ayesha Saeed ◽  
Mian Maqbool Hussain ◽  
Mumtaz Hussain ◽  
Abdul Latif Sami ◽  
...  

Background: The Ponseti technique is the gold standard for treatment of clubfoot. However, the data in walking children is still limited and results are ill defined. Aim: We prospectively compared Ponseti method in clubfoot patients aged <2 and between 2 to 5 years in our local scenario. Methods: A total of 40 patients were included in the study through non-probability purposive sampling. The patients were examined, classified (Goldner and Fitch classification) and demographic information was recorded. They were explained about the risk and informed consent was taken. In group A, patients were below 2 years of age while in group B, patients were between 2-5 years of age. Ponseti casting was performed by a designated team. Follow-up was done for 6 months from the correction of feet. Results: We received 27(67.5%) male and 13(32.5%) female patients .The male to female ratio was 2:1. The mean age of patients in group A and B was 0.8±0.70 years and 4.3±2.1 years respectively. There was no statistical difference of severity of deformity of clubfoot in both study groups, p-value>0.05. In group A, 17 (85%) patients had success of procedure while in group B the success was achieved in 11 (55%) patients. The success rate was statistically significantly higher in group-A as compared to group B, p-value<0.001 Conclusion: Patient aged <2 years have significantly higher success rate as compared to patients aged between 2-5 years. So we recommend the Ponseti method as standard therapy in clubfoot management for patients with age<2 years and for correction of mild and moderate deformities in patients between 2 to 5 years. Keywords: Clubfoot, Congenital talipes equinovarus, Ponseti method


2015 ◽  
Vol 5 (1) ◽  
pp. 1-5
Author(s):  
Tareq Hassan ◽  
Sohana Ferdous ◽  
Aslam Md Aurangjeb

Fiber reinforcement was introduced to clinical dentistry for the first time in the 1960s when investigators attempted to reinforce polymethyl-methacrylate dentures with glass or carbon fibers. It has recently been shown that crowns, bridges and posts made of FRC can be used successfully in dental practice and on the basis of marginal adaptation they are more acceptable than conventional metal ceramic crown. A prospective comparative cross-sectional study was performed involving 60 patients who attended in the out patients department of Prosthodontics, Faculty of Dentistry, BSMMU during the period of January 2007 to December 2008. Clinical data were recorded for the selected 60 patients who were divided into two groups “experimental” and “control”. Marginal adaptation was indexed after California Dental Associations quality evaluation system. The age of the patients ranged from 18 to 42 years in group A and 17 to 38 years in group B. The highest number of patients was in the age group 21-30 years in both the groups. The mean age was 24.9±5.8 years and 25.0±4.8 years in group A and group B respectively. There were 26 male and 34 female patients in the study and male female ratio was 1:1.3. In group A patients, 12(40.0%) were male and 18(60.0%) female. In group B patients 14(46.7%) were male and 16(53.3%) were female. After 4 months all the patients were in grade I in both the groups. After 8 months all the patients were in grade I in group A and 27(90.0%) patients in grade I in group B.  After 12 months all the patients were in grade I in group A and 25(83.3%) patients were in grade I in group B. The difference was not statistically significant (p>0.05) after 8 months, however after 12 months the difference was significant (p<0.05). The Fiber Reinforced Composite crown represents a valuable development in the field of Prosthetic Dentistry. DOI: http://dx.doi.org/10.3329/bjdre.v5i1.22450 Bangladesh Journal of Dental Research and Education Vol.5(1) 2015: 01-05


2014 ◽  
Vol 42 (2) ◽  
pp. 55-59
Author(s):  
MT Islam ◽  
MA Shakoor ◽  
MA Emran ◽  
KMT Islam ◽  
MG Nobi ◽  
...  

This experimental study was done in the Department of Physical Medicine and Rehabilitation, Bangabandhu Sheikh Mujib Medical University to find out the effects of lumbar corset on the patients with lumbar spondylosis. Ninety seven patients were selected in the study. Out of them 40(41.24%) were male and 57(58.76%) were female. The male to female ratio was 1:1.42. The mean age was 41.22 ± 8.52 years. The patients were divided into two groups, 50 patients in group A ( Treated with NSAID, activities of daily living instructions and lumbar corset) and another 47 patients in group B (Treated with NSAID and activities of daily living instructions only ). In both the groups, patients were treated for six weeks and assessed at 7 days interval. Improvement was noticed in both the groups in every visit but there was no difference in improvement between the groups till 4th week of treatment. At the end of treatment group A showed statistically significant difference in overall improvement in comparison to group B. So, from the present study, it may be concluded that lumbar corset is beneficial to the patients with lumbar spondylosis. DOI: http://dx.doi.org/10.3329/bmj.v42i2.18987 Bangladesh Med J. 2013 May; 42 (2): 55-59


2020 ◽  
Author(s):  
Xiao Huang ◽  
Changwei Wei ◽  
Jing Wang ◽  
Dandan Lin ◽  
Juxia Zhang ◽  
...  

Abstract BackgroundTo investigate the difference of demographic, health status and clinical characteristics of patients with or without insomnia postoperatively, and to identify the potential risk factors of insomnia.Methods299 patients undergoing surgery were included. Patients were divided into group A (insomnia, N = 78) and group B (without insomnia, N = 221). Insomnia Severity Index (ISI), Patient Health Questionnaire-9 (PHQ-9), Generalized Anxiety Disorder (GAD-7), and Montreal cognitive assessment (MoCA) were applied to all patients preoperatively. Visual Analogue Scale (VAS) was assessed preoperatively, and at the end of the surgery, one day after surgery, two days after surgery and three days after surgery. The PHQ-9, the GAD-7 and the ISI were reassessed three days after surgery. Information on sociodemographic variables and demographic data were collected.ResultsAmong the two groups, the average points patients got in the ISI, PHQ-9 and the GAD-7 in group A were also significantly higher than those in group B. The VAS score 3 days after surgery was significantly higher in group A. The PHQ-9 and the GAD-7 3 days after surgery showed significantly higher depression and anxiety scores in group A. Logistic regression showed ISI (P < 0.001, 95%CI = 1.218-1.500), the GAD-7 (P = 0.01, 95%CI = 0.712–0.954) preoperatively and the PHQ-9 postoperatively (P < 0.001, 95%CI = 1.226–1.555) were risk factors of insomnia.ConclusionsInsomnia is common in patients, which worsen after surgery. The present study suggests that depression and anxiety are risk factors of poor sleep quality after surgery. There is a need for further research and strategies for depression and anxiety management to achieve better sleep and significant health benefits in these patients.Trial registration: clinical trial, NCT04027751. Registered 22 July 2019, https://clinicaltrials.gov/ct2/show/NCT04027751?cond=NCT04027751&cntry=CN&draw=2&rank=1.


2020 ◽  
Vol 4 (1) ◽  
pp. e1-e12
Author(s):  
Deep Kumar Jain ◽  
Padmaraj Hegde ◽  
Arun Chawla

ObjectivesTo comparatively evaluate the outcomes of standard percutaneous nephrolithotomy (PCNL) versus a 36 Fr PCNL in terms of operative time, complications, hospital stay, and stone free rates. Patients and MethodsThe data of 125 PCNL cases, out of the 168 PCNLs done from January 2014 to December 2015, was retrospectively analyzed within two subsets, namely group-A (standard PCNL with 22-32 Fr Amplatz) and group-B (modified large PCNL with 36 Fr Amplatz). The demographic profile, stone characteristics, operative and laboratory parameters, and stone clearance rate were analyzed to determine the safety and efficacy of the modified large PCNL as against standard PCNL. ResultsGroup-A comprised 88 patients with 100 renal units, while group-B comprised 37 patients with 45 renal units. The mean age of the patients in Group-A was 49.1 + 13.1 years, and in Group-B was 52.4 + 11.4 years (range 25-84 years) with a male to female ratio of 4:1. 54.5% and 75.7% unilaterally intervened, group-A and group-B patients respectively, required < 90 minutes for the procedure. Nine patients (10.2%) each of unilaterally and bilaterally intervened group-A cases had an operative time that exceeded 120 minutes compared to only two (5.4%) bilaterally intervened group-B cases. For patients with stone burden >1000 mm2, there was statistically significant (p = < 0.0001) higher complete stone clearance rates with the 36Fr PCNL compared to standard PCNL. ConclusionOur retrospective analysis revealed that 36 Fr PCNL is safe and efficacious in carefully selected patients with large stone burdens providing the advantage of better stone-free rates, less operative time, lesser need for additional punctures without increasing blood transfusion and complications rates. However, more extensive prospective randomized trials are needed to confirm this perceived benefit.


2013 ◽  
Vol 37 (1) ◽  
pp. 47-51
Author(s):  
Mustafa A.K. Al-Taie

In this study blood samples were collected from 150 newborns (NBs), In a period from 20082010, with blood groups A and B from mother’s blood group O positive and those who do not have any other reason for the jaundice..Of 150 NBs, 105 have blood group A and 45 with group B. And the male to female ratio was 1.7:1. The average of NBs age at the onset of jaundice was 19.02 hrs, it was earlier in blood group B and in newborns of first pregnancy. The average of serum bilirubin level at 24 hours was 5.70 mg/dl; there was no statistical value of the blood group and the sex of the NBs in the bilirubin level. Newborns had anemia at delivery in 12 cases, 6 of them were premature. Fifty one NBs were followed for late anemia and found 36 (70%) had anemia. Comparing results between NBs who had anemia and those who had not, found that the bilirubin level was higher in anemic NBs, and they had longer stay in Hospital


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