Prevalence of Thrombocytopenia in Neonates Born to Mothers with Pregnancy Induced Hypertension

2021 ◽  
Vol 15 (9) ◽  
pp. 2887-2889
Author(s):  
Anum Masood ◽  
Raushan Jahan ◽  
Asima Khanam ◽  
Shaista Khanam ◽  
Tabassum Firdous ◽  
...  
Keyword(s):  
Neonatal Intensive Care ◽  
Cross Sectional Study ◽  
Severe Thrombocytopenia ◽  
Pregnancy Induced Hypertension ◽  
Cross Sectional ◽  
Female Ratio ◽  
Induced Hypertension ◽  
Neonatal Thrombocytopenia ◽  
The Mean ◽  
Male To Female

Background: Pregnant women with hypertension are at high risk to deliver a newborn with severe thrombocytopenia. Little is known concerning the magnitude of thrombocytopenia in neonates born to mothers with PIH and controversy was also present. Objective: To determine the frequency of thrombocytopenia in neonates born to mothers with pregnancy induced hypertension. Material & Methods: This cross sectional study was carried out at department of Neonatology, Lady Aitcheson Hospital, Lahore for 6 months. A sample of 1ml from cord blood was taken and sent to hematology laboratory. Neonatal thrombocytopenia was labeled. All the data was entered and analyzed on SPSS version 16. Results: The mean age of babies was 13.31±7.07 days. The male to female ratio was 1.1:1. The mean platelet count of the babies was 150.23±29.39. Thrombocytopenia was present in 41.50% babies. Conclusion: Prevalence of thrombocytopenia was 41.5% in females with PIH. Keywords: Thrombocytopenia, Pregnancy Induced Hypertension, Mothers, Neonates, Neonatal Intensive care unit

scholarly journals ASSOCIATION OF HUMAN CHORIONIC GONADOTROPHIN WITH PREGNANCY INDUCED HYPERTENSION

2020 ◽  
Vol 70 (6) ◽  
pp. 1712-16
Author(s):  
Nayab Afzal Chatha ◽  
Humaira Osman Jaffery ◽  
Saima Qamar ◽  
Nilofar Mustafa ◽  
Rizwana Kamran ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Cross Sectional Study ◽  
Chorionic Gonadotrophin ◽  
Human Chorionic Gonadotrophin ◽  
Military Hospital ◽  
Pregnancy Induced Hypertension ◽  
Cross Sectional ◽  
Induced Hypertension ◽  
The Mean ◽  
Beta Human Chorionic Gonadotrophin

Objective: To determine the positive predictive value of beta Human Chorionic Gonadotrophin in early secondtrimester for predicting pregnancy induced hypertension. Study Design: Cross-sectional study. Place and Duration of Study: Department of Obstetrics and Gynaecology Combined Military Hospital, Lahore,from Jun 2017 to Nov 2017. Methodology: A total of 214 female pregnant patients met the criteria for inclusion in this study. Patients withbeta human chorionic gonadotrophin (βHcg) levels ≥2 MoM were followed at 22, 26, 30 and 34 weeks of gestation. Blood pressure was monitored. Pregnancy induced hypertension (PIH) was labelled after 20 weeks (as per dating scan) of gestation in patients who did not have proteinuria (≥300 mg 24 hour urine sample) and had a systolic blood pressure ≥140 mmHg and/or a diastolic blood pressure ≥90 mmHg (blood pressure readings taken at two separate points in time four hours apart). Results: Patients ranged between 18-35 years of age, with the mean age being 27.3 ± 4.3 years. Mean gestational age was observed to be 15.6 ± 1.8 weeks. Mean BMI was 23.8 ± 3.2 kg/m2. Out of 214 patients, 30 patients (14%) had beta human chorionic gonadotrophin level >2 MoM. Out of these 30 patients, 25 patients (83.3%) developed PIH. There were 100 primigravida (46.7%) and 114 multigravidas (53.3%). Beta human chorionic gonadotrophin in predicting pregnancy induced hypertension showed sensi-tivity of 96.1%, a specificity of 97.3%, with a PPV83.3%, a NPV 99.4% and diagnostic accuracy of 97.2%.

scholarly journals Profile of Secondary Glaucoma in a Tertiary Eye Hospital of Eastern Nepal

2021 ◽  
Vol 13 (1) ◽  
pp. 98-103
Author(s):  
Jamuna Gurung ◽  
Rakshya Pant Sitoula ◽  
Anjani Kumar Singh
Keyword(s):  
Optic Atrophy ◽  
Cross Sectional Study ◽  
Secondary Glaucoma ◽  
Sectional Study ◽  
Cross Sectional ◽  
Female Ratio ◽  
Poor Vision ◽  
Post Traumatic ◽  
The Mean ◽  
Male To Female

Background: To determine the clinical profile and causes of various types of secondary glaucoma. Materials and methods : This was a hospital-based cross-sectional study conducted in a tertiary eye hospital of eastern Nepal from 1st June to 30th November, 2017. Patients who met the criteria for secondary glaucoma underwent detailed ophthalmic examination. Results : Out of 7079 patients diagnosed with glaucoma or glaucoma suspects, 528 (7.4%) had secondary glaucoma. The mean age at presentation was 52 ± 17 years with male to female ratio of 1.5:1. The most common cause was lens induced 173 (32.8%) followed by neovascular 107 (20.3%), steroid induced 86 (16.3%), traumatic 76 (14.4%), post-vitrectomy 17 (3.2%), uveitic 11 (2.1%), pseudophakic 10 (1.9%), aphakic 8 (1.5%), post-keratoplasty 5 (0.9%) and miscellaneous included 35 (6.6%). Post-traumatic 31 (29.5%) was more prevalent below 41 years while lens induced glaucoma 86 (49%) above 60 years of age. At presentation, the average IOP was 40 ± 11 mmHg. 36 (6.8%) had no light perception in the presenting eye and a large number of participants 307 (58.1%) presented with visual acuity of <3/60 to perception of light. Glaucomatous optic atrophy was found in 22 (9.0%) cases.  Conclusion : The causes of secondary glaucoma are diverse, lens induced glaucoma being most common. Most patients present late with poor vision, high IOP and even glaucomatous optic atrophy. So, early identification and treatment of the causes is important so that we can prevent the burden of blindness due to secondary glaucoma.

scholarly journals Sensitivity of electroencephalogram in the diagnosis of epilepsy among patients attending a neuropsychiatric hospital in Northern Nigeria

2020 ◽  
Vol 3 (1) ◽  
Author(s):  
Shehu Sale
Keyword(s):  
High Sensitivity ◽  
Epileptic Seizures ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Female Ratio ◽  
Future Studies ◽  
Duration Of Illness ◽  
The Mean ◽  
Male To Female ◽  
Ethical Clearance

Electroencephalography (EEG) is an essential adjunct in management of epilepsy. While some studies reported that EEG has a high sensitivity in detecting epileptic seizures, others disagree. Therefore, it is important to know sensitivity of this important procedure in our setting. This was a cross-sectional study carried out from 2015 to 2018. Participants were patients attending the outpatient clinic of a psychiatric hospital to achieve care for epileptic seizures. Ethical clearance was obtained prior to the conduct of this study. In addition, informed consent was obtained from each patient or their caregivers. Data analysis was done using SPSS version 20. The study involved 177 participants aged 2-70 years (median = 17 years). The male to female ratio was 2:1. The mean duration of illness was 7.8±5.8 (range = 1-35 years). Sensitivity of EEG was 70.6%. There was no difference between either age, gender or duration of illness and probability of having an abnormal EEG. EEG is sensitive in the diagnosis of epilepsy in our setting. Future studies should focus on factors influencing sensitivity of EEG in diagnosis of epilepsy.

scholarly journals Association between hypertension and the severity of new onset ischemic stroke in Diabetic patients

2020 ◽  
Vol 28 (1) ◽  
pp. 7-10
Author(s):  
Hashmi Sina ◽  
Tamanna Mustary ◽  
Kazi Gias Uddin Ahmed ◽  
Ahmed Hossain Chowdhury ◽  
Kanol Saha ◽  
...  
Keyword(s):  
Ischemic Stroke ◽  
Cross Sectional Study ◽  
Current Smoker ◽  
Diabetic Patients ◽  
Cross Sectional ◽  
Female Ratio ◽  
Medical College ◽  
The Mean ◽  
Male To Female ◽  
New Onset

Objective: To evaluate the association between hypertension and the severity of new onset ischemic stroke patient with diabetes mellitus. Method: This Cross sectional study was carried out in the Department of Neurology, BSMMU, Dhaka, from February 2013 to September 2014 on 50 patients with first attack of ischemic stroke with DM. mRS was measured on 14th day of the stroke. During this period other important relevant investigations were also recorded. Result: In this study, out of 50 patients, 40.0% were in age group 51-60 years and the mean age of the patients was 58.9 ± 9.6 years with a range from 30 to 75 years. Males were 52.0% and females were 48.0%. Male to female ratio was 1.08:1. It was observed that more than one third (36.0%) patients were current smoker, 9(18.0%) were former smoker and 23(46.0%) were non smoker. More than half of the patients had hypertension (58.0%). Mean systolic BP was 129 ±16 mmHg with a range from 90 to 160 mmHg and the mean diastolic BP was 81±11 mmHg with a range from 60 to 100 mmHg. No association was found between hypertension with severity of new onset ischemic stroke in Diabetic patients. Conclusion: As per study result it can be concluded that there is no association between hypertension and the severity of new onset ischemic stroke in Diabetic patients. J Dhaka Medical College, Vol. 28, No.1, April, 2019, Page 7-10

scholarly journals BILIARY ATRESIA

2018 ◽  
Vol 25 (11) ◽  
pp. 1638-1642
Author(s):  
Aysha Anjum ◽  
Saba Maqsood ◽  
Eisha Tahir
Keyword(s):  
Biliary Atresia ◽  
Cross Sectional Study ◽  
Porta Hepatis ◽  
Cross Sectional ◽  
Female Ratio ◽  
Non Invasive ◽  
Standard Design ◽  
The Mean ◽  
Male To Female ◽  
Future Practice

Objectives: To determine the accuracy of ultrasound in diagnosing biliary atresiataking histopathology as gold standard. Design: Cross Sectional Study. Settings: Departmentof Diagnostic Radiology and Gastroenterology at Children’s Hospital and Institute of ChildHealth, Lahore. Period: Over 1 year from 13-01-2015 to 12-02-2016. Material and Methods:This study involved 210 infants aged between 2-6 weeks referred from outpatient departmentand emergency of gastroenterology department with suspicion of biliary atresia. Ultrasoundof all these cases was carried out and biliary atresia was labeled on a positive triangular cordsign. Core needle biopsy sample was taken from the liver adjacent to the porta hepatis andhistopathological examination was done. Results of histopathology were taken as gold standardand results of ultrasonography were judged accordingly as true positive or false positive. Awritten informed consent was taken from each patient. A predesigned proforma was used torecord patient’s demographic details along with ultrasound and histopathological diagnosis.Results: The mean age of the patients was 4.31±1.22 weeks. There were 109 (51.9%) maleand 101 (48.1%) female patients with a male to female ratio of 1.1:1. Ultrasound was found97.5% sensitive, 87.7% specific and 95.2% accurate with positive and negative predictive valueof 96.31% and 91.5%, respectively. Conclusion: Ultrasound was found extremely sensitive toolfor the diagnosis of biliary atresia. Its non-invasive nature and lack of radiation exposure furthermake it ideal for pre-operative diagnosis in suspected cases in future practice.

Frequency of High MELD Score in Cirrhotic Patients undergoing Liver Resection due to Hepatocellular Carcinoma

2021 ◽  
Vol 15 (9) ◽  
pp. 2841-2843
Author(s):  
Muhammad Omer Farooq ◽  
Niaz Ahmed ◽  
Hassan Nadeem ◽  
Kashif Rafi ◽  
Sadia Jabbar ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Liver Resection ◽  
Cross Sectional Study ◽  
Meld Score ◽  
Cross Sectional ◽  
Female Ratio ◽  
Score Study ◽  
Insignificant Difference ◽  
Cirrhotic Patients ◽  
Male To Female

Objective: To determine the frequency of high MELD score in cirrhotic patients undergoing liver resection due to hepatocellular carcinoma also compare the frequency of mortality in patients with high or low MELD score. Study Design: Cross sectional study Place and Duration: Department of Gastroenterology, Shaikh Zayed Hospital, Lahore. Duration: 6months i.e. 23 12-2017 to 22-06-2018. Methodology: 75 patients were enrolled. Then blood sample was obtained. Reports assessed and MELD score calculated. Scores were labeled as high or low. Patients underwent liver resection according to BCLC. The mortality was noted. All the collected data was entered and analyzed on SPSS version 22. Results: In this study out of total 75 cases 60 were males and 15 females. The mean age of patients was 39.44±9.76 years, male to female ratio was 4:1. Low MELD class was noted in 45 (60%) cases and high MELD class noted in 30(40%) cases. Mortality occurred in 27(36%) cases. Insignificant difference found between the MELD class with mortality. Conclusion: High MELD score was seen in 40% cirrhotic patients undergoing liver resection due to HCC. Post HCC resection, mortality occurred in 36% patients within three months of surgery. No significant association was found between the mortality and MELD score. Keywords: MELD, Hepatocellular Carcinoma, Mortality, Cirrhosis

Incidence of Pregnancy Induced Hypertensive Women and its Associated Factors

2021 ◽  
Vol 15 (12) ◽  
pp. 3307-3309
Author(s):  
Samia Saifullah ◽  
Maryam Shoaib ◽  
Muhammad Sohail Tareen ◽  
Nosheen Sikander Baloch
Keyword(s):  
Blood Pressure ◽  
Family History ◽  
Pregnant Women ◽  
Cross Sectional Study ◽  
Mean Value ◽  
Renal Diseases ◽  
Pregnancy Induced Hypertension ◽  
Cross Sectional ◽  
Induced Hypertension ◽  
Keywords Pregnancy

Background: Pregnancy induced hypertension is a fetal disease resulting into morbidity and mortality of female as well as its neonate. Objective: To find the incidence of pregnancy induced hypertension in Pakistani women. Study Design: Cross sectional study Place and Duration of the Study: Department of Obstetrics & Gynaecology, Sandeman Provincial Hospital, Quetta from 1st March 2019 to 31st March 2021. Methodology: Seven hundred and twenty eight females were identified with pregnancy induced hypertension from all the pregnant women attending the outdoor were enrolled. Each female was checked for their protein urea as well as systolic and diastolic blood pressure according to standard operating protocol. Socio-demographic, clinical and family history were documented. Results: Among all pregnant women, 150 were identified as pregnancy induced hypertensive with a 20.6% incidence of pregnancy induced hypertension. The mean value systolic blood pressure value was 144.3±5.2 and of diastolic as 83.1±5.2 in pregnancy induced hypertension women. Conclusion: Family history, obesity and renal diseases are the main factors associated with pregnancy induced hypertension with an incidence of 20.6% among pregnant women. Keywords: Pregnancy induced hypertension, Body mass index, Pregnant women, Hypertension

scholarly journals Perinatal Findings in Pregnancy Induced Hypertension: A Study in a Tertiary Teaching Hospital in Dhaka City

2017 ◽  
Vol 2 (1) ◽  
pp. 10-13
Author(s):  
Zobaida Sultana Susan ◽  
Surayea Bulbul ◽  
Jannat Ara Ferdows ◽  
Abu Nayeem
Keyword(s):  
Cross Sectional Study ◽  
Fetal Mortality ◽  
Pregnancy Induced Hypertension ◽  
College Hospital ◽  
Cross Sectional ◽  
Mortality And Morbidity ◽  
Tertiary Teaching ◽  
Induced Hypertension ◽  
Questionnaire Result ◽  
In Pregnancy

Background: Hypertensive disorders are common complication occurring during pregnancy which are responsible for maternal and fetal mortality and morbidity. Objective: The purpose of the present study was to determine the perinatal outcome in pregnancy induced hypertension. Methodology: This study was designed as cross-sectional study and was conducted from April 2013 to September 2013 for a period of six (06) moths. Patients admitted in the Department of Obstetrics and Gynaecology at Shaheed SuhrawardyMedical College Hospital, Dhaka. Data were collected by interview, physical examintions (blood pressure, pulse rate, oedema, heart and lungs auscultation) and lab investigations using a structural questionnaire. Result: Majority of the women belonged to age group 21-25 year. Maximum were (56%) primigravida. The mean gestational age was 34.6 weeks with the range from 28 to 40 weeks. Hyperurecaemia was frequent among patients with pregnancy induced hypertension. Intrauterine growth retardation (IUGR) was secondary to pregnancy induced hypertension which was associated with significantly increased perinatalmortality. Conclusion: In this study, prematurity is frequent in pregnancy induced hypertension and convulsion in nonresponsive patients is associated with significantly increased perinatal mortality.Journal of National Institute of Neurosciences Bangladesh, January 2016;2(1): 10-13

HIV Prevalence and Frequency of Risk Behavior in Injecting Drug Users Entering Treatment and Out of Treatment: A Cross-Sectional Study in Five Italian Cities

1994 ◽  
Vol 24 (3) ◽  
pp. 527-535 ◽  
Author(s):  
Giovanni Rezza ◽  
Stefania Salmaso ◽  
Damiano Abeni ◽  
Giovanna Brancato ◽  
Alessandra Anemona ◽  
...  
Keyword(s):  
Risk Behavior ◽  
Drug Users ◽  
Injecting Drug Users ◽  
Cross Sectional Study ◽  
Hiv Prevalence ◽  
Sectional Study ◽  
Cross Sectional ◽  
Female Ratio ◽  
Outreach Programs ◽  
Male To Female

We conducted a study to describe current patterns of drug-related behaviors, and to identify characteristics that may distinguish injecting drug users entering treatment from those out of treatment, in five Italian cities. Overall, 1,180 subjects were recruited — 568 entering treatment and 612 out of treatment. Male to female ratio was 6.6:1. The median age was similar in the two groups. A high proportion of injecting drug users recruited out of treatment had been in treatment at least once. HIV prevalence among injecting drug users entering treatment was not higher than that of those who were out of treatment. Furthermore, a large proportion of injecting drug users who still were out of treatment reported having adopted safe behaviors. The results of the study emphasize the need to implement outreach programs aimed at harm reduction.

scholarly journals Does Static Intra Access Pressure Monitoring of Arteriovenous Fistulas Predicts Intra Access Stenosis?

2021 ◽  
Vol 4 (03) ◽  
Author(s):  
Abaid ur Rehman ◽  
Muhammad Imran Khan ◽  
Omer Sabir ◽  
Muhammad Mohsin Riaz ◽  
Mubashar Dilawar ◽  
...  
Keyword(s):  
Diagnostic Accuracy ◽  
Vascular Access ◽  
Doppler Ultrasonography ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Female Ratio ◽  
Arteriovenous Fistulas ◽  
Doppler Us ◽  
Sensitivity Specificity ◽  
Male To Female

The initiation of hemodialysis in patients with chronic kidney disease (CKD) requires vascular access formation. The choice of vascular access for individual patient depends on various factors however arteriovenous fistula (AVF) is conventionally considered to be the vascular access of choice. Once hemodialysis is initiated through a mature AVF, there is an ongoing need for surveillance of the AVF to ensure adequate function and prevent vascular access issues among which flow obstruction (both inflow and outflow) remains the most important. AVF stenosis can potentially lead to inadequate dialysis delivery and thrombosis thus leading to access loss. Physical examination and AVF Doppler ultrasonography (DUS) are useful for evaluation of stenosis in the  arteriovenous connection and the outflow tract. Periodic assessment of the AVF with Static Intra access Pressure (SIAPR) determination may be a reliable means of predicting vascular access stenosis. Material & Methods  A cross sectional study carried out at Department of Nephrology, Fatima Memorial Hospital, Lahore from July 2018 to December 2018. In total 113 patients were included, and all patients underwent SIAPR assessment and Doppler Ultrasound of AVF. Results Mean age of the patients was 56.81±9.38 years, male to female ratio of the patients was 1.8:1. In this study the SIAPR was suggestive of  stenosis in 87(76.99%) patients. The sensitivity, specificity and diagnostic accuracy of SIAPR against Doppler US of the AVF for detection of stenosis was 75.86%, 22.62% & 36.28% respectively Conclusion SIAPR has low specificity and diagnostic accuracy compared to Doppler US for detection of AVF stenosis.

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