scholarly journals Lipid Abnormalities Using Random Sampling In Patients With End Stage Renal Disease On Thrice Weekly Hemodialysis

2021 ◽  
Vol 4 (4) ◽  
pp. 328-331
Author(s):  
Shahid Anwar ◽  
Alvina Zainab ◽  
Sobia Mazhar

Background: Cardiovascular disease (CVD) is the leading cause of death in the dialysis population. Among other risk factors abnormalities in lipid metabolism occur in patients with all stages of chronic kidney disease (CKD). The most common dyslipidemia in CKD and dialysis is hypertriglyceridemia, whereas the total cholesterol concentration can be normal or low, perhaps due in part to malnutrition. Although  hypertriglyceridemia that occurs in CKD may not significantly increase coronary risk, other changes may contribute to the accelerated atherosclerosis. We tried to find out how many patients in our setup on thrice weekly hemodialysis are suffering from dyslipidemia and whether taking treatment or not. Methodology: Cross sectional study conducted at dialysis center of Sir Ganga Ram Hospital, Lahore including all seventy patients with ESRD undergoing regular HD three times a week, 4 hours per session. Random blood samples (Non-fasting) were collected before dialysis for lipid profile including serum triglyceride, LDL, HDL and total cholesterol. Results: Out of 70 patients only 3 (4.4%) patients were on statins for dyslipidemia. Triglycerides were high in 41.4%, total cholesterol was low in 61.4%, and HDL was low in 34.3%. Conclusion: Hypertriglyceridemia is major lipid abnormality among hemodialysis patients.

2014 ◽  
Vol 2014 ◽  
pp. 1-4 ◽  
Author(s):  
F. Z. Souilmi ◽  
T. Sqalli Houssaini ◽  
G. EL Bardai ◽  
N. Kabbali ◽  
M. Arrayhani ◽  
...  

Hemodialysis is the most used renal replacement therapy for children in Morocco. The objective of this study was to determine the prevalence of patients who started hemodialysis in childhood and study their characteristics and specificities of their care. For this we conducted a multicentric descriptive cross-sectional study of all chronic hemodialysis patients who started dialysis in pediatric age, in hemodialysis centers in four of the sixteen regions of Morocco. We collected 2066 patients undergoing dialysis in 39 hemodialysis centers; from these, only 72 patients (3.48%) started hemodialysis in childhood. The average age of patients was 20.64 ± 6.5 years with a sex ratio of 1.9. Duration of dialysis was 78.2 ± 56 months. The cause of end stage renal disease was urological abnormalities in 18% of cases and glomerulopathy in 12.5% of cases; however, it remains unknown in half of the patients. Over 18 years, 74% of patients are without profession, it is active in 13% of cases, and pursuing studies are only in 13% of cases. Patients under 5 years and those with a low weight are rarely taken care of in chronic hemodialysis with little individualization of prescription. Greater attention should be paid to renal transplantation that is desired by the majority of these patients (92%).


PLoS ONE ◽  
2020 ◽  
Vol 15 (11) ◽  
pp. e0241201
Author(s):  
Zaher Nazzal ◽  
Shahd Khader ◽  
Hiba Zawyani ◽  
Mazen Abdallah ◽  
Osama Sawalmeh ◽  
...  

Introduction End-Stage Renal Disease (ESRD) is the ultimate result of chronic kidney disease (CKD). In Palestine, the prevalence of ESRD was 240.3 PMP which is comparable with the nearby countries. Accelerated bone loss among ESRD patients is attributed to abnormal bone turn over that leads to osteoporosis and osteopenia. The risk of fractures is increased four-fold in men and women on hemodialysis, which explains the importance of assessing the bone mineral density among these population. The goals of this study were to find the prevalence of osteoporosis in ESRD patients as determined by bone mineral density (BMD) at different sites and to determine whether BMD correlates with many other clinical parameters. Methods A cross-sectional study of 194 ESRD patients were recruited from the dialysis unit in An-Najah National University Hospital, Nablus, Palestine. The patients were on regular hemodialysis or peritoneal dialysis. BMD was measured at the lumbar spine and the hip using the dual-energy X-Ray absorptiometry (DEXA) and the value is expressed as T-score. The data were analyzed using SPSS, version 26. The relationship between BMD and the clinical and biochemical parameters among the ESRD patients was assessed. Results We found that 42.8% of ESRD patient had osteoporosis and 40.2% had osteopenia. There were significantly higher proportions of osteoporosis and osteopenia among patients >60 years of age (p<0.005). Patients with osteoporosis and osteopenia had significantly higher serum levels of PTH (792.9 and 469.7) (p<0.05). BMD decreases as the duration of dialysis (39.0 months Vs. 56.8 months), (p<0.05). We found no significant difference between patients on hemodialysis or peritoneal dialysis. Conclusion This study showed that Palestinian patients with ESRD have low BMD at the hip and spine. The observed high serum level of PTH was associated with low BMD. Those patients should be closely monitored especially those with more than one risk factor. Moreover, more attention should be paid for these category of patients to decrease the incidence of falling down and the resulting fractures that might lead to mortality and morbidity.


2020 ◽  
Vol 58 (226) ◽  
Author(s):  
Kajan Raj Shrestha ◽  
Dinesh Gurung ◽  
Uttam Krishna Shrestha

Introduction: Arteriovenous fistula is the most common vascular access for patients requiringhemodialysis, but it is not always possible or practical hence cuffed tunneled dialysis cathetercomes into play. The aim of the study was to determine the outcome of cuffed tunneled dialysiscatheter used for hemodialysis at a teaching hospital. Methods: A descriptive cross-sectional study was conducted between January 2014 and December2019 on 103 chronic dialysis patients with end-stage renal disease presenting to a tertiary carehospital. Ethical approval was received from the institutional review board (2/(6-11) E2/076/77).Whole sampling was done. Data entry and analysis were done in Microsoft Excel 10. Results: The study included 103 patients with 117 cuffed tunneled dialysis catheters placed forhemodialysis. On assessing the outcome of the catheters, the primary and secondary patencyrates of the catheters were 5.85±4.87 and 1.21±3.77 months. Thirty-one (30.1%) patients requiredone intervention, and 11 (10.68%) catheters required 3 or more interventions to maintain patency.Eighteen (17.48%) patients presented with catheter dysfunction while in 11 (10.68%) cases, thecatheter was kinked or malpositioned at the notch. In one patient, procedure was abandoned dueto severe bleeding and in 2 (1.94%) patients dialysis catheters could not be negotiated into the rightatrium and left in brachiocephalic junction. Conclusions: Cuffed tunneled dialysis catheter is effective for maintenance hemodialysis in patientswith the end-stage renal disease if used with proper care during dialysis even in our setup. Theresults and outcomes of the procedure are at par with standards.


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