Effect of rehabilitation nursing training on neurological function of senile cerebral infarction and recovery of hemiplegic limbs

2021 ◽  
Keyword(s):  
Cerebral Infarction ◽  
Neurological Function ◽  
Nursing Training

scholarly journals Early path nursing on neurological function recovery of cerebral infarction

2019 ◽  
Vol 10 (1) ◽  
pp. 160-163
Author(s):  
Ling Chen ◽  
Zhena Han ◽  
Junjie Gu
Keyword(s):  
Cerebral Infarction ◽  
Conventional Treatment ◽  
Neurological Function ◽  
Early Rehabilitation ◽  
Control Group ◽  
P Value ◽  
Treatment Methods ◽  
Rehabilitation Care ◽  
Function Recovery ◽  
Experimental Group

Abstract Purpose to study the application of path type early rehabilitation nursing in the nursing of patients with cerebral infarction and to explore its impact on the recovery of neurological function. Methods Patients with acute cerebral infarction in our hospital were randomly divided into two groups. The control group used conventional treatment methods. The experimental group used path type early rehabilitation care based on conventional treatment methods and observed the curative effect. ResultsThe NIHSS scores in the experimental group were significantly lower than those in the control group, and the P value was less than 0.05, which was statistically significant. Conclusion Path type early rehabilitation nursing has a positive effect on the treatment of patients with cerebral infarction, which contributes to the recovery of neurological function of patients and is worthy of promotion in treatment.

scholarly journals Effect of Hip Fracture on Prognosis of Acute Cerebral Infarction

BioMedica ◽  
2021 ◽  
Vol 37 (2) ◽  
pp. 114-118
Author(s):  
Jiawen Yuan ◽  
Gang Zhu ◽  
Yuwu Zhao ◽  
Jiankang Huang
Keyword(s):  
Surgical Treatment ◽  
Hip Fracture ◽  
Mortality Rate ◽  
Cerebral Infarction ◽  
Recovery Rate ◽  
Neurological Function ◽  
Acute Cerebral Infarction ◽  
Control Group ◽  
Vein Thrombosis ◽  
Hospitalization Period

<p><strong>Background and Objective:</strong> The guidelines on the factors to determine whether a patient with concomitant stroke and hip fracture is a good candidate for surgical hip repair are still debatable. This study was carried out to investigate the relationship between the management of acute hip fracture and the recovery of neurological function and prognosis in patients with concomitant acute cerebral infarction.</p> <p><strong> Methods:</strong> Thirty patients with acute cerebral infarction combined with acute hip fracture, who were hospitalized and did not accept surgical treatment, and matched 60 cases as control group having acute cerebral infarction without hip fracture admitted in the same period were selected. The neurological function recovery, hospitalization period, 6 months recovery rate, frequency of complications, and 1 year mortality rate between the groups were compared.</p> <p><strong>Results: </strong>Compared with common acute cerebral infarction patients, the NIH Stroke Scale/Score of acute cerebral infarction group with hip fracture was higher (7.2 &plusmn; 5.4 vs. 5.6 &plusmn; 4.3, p = 0.034). The hospitalization period was prolonged (16.1 &plusmn; 8.9 vs. 12.2 &plusmn; 5.3, p = 0.041), and 6 months recovery rate was lower (26.7% vs. 53.3%, p = 0.016), the frequency of pulmonary infection and lower extremity deep vein thrombosis was higher (30% vs. 11.7%, p = 0.03; 6.7% vs. 0, p = 0.043). The 1-year mortality rate in patients with combined hip fracture was higher than in patients with cerebral infarction only.</p> <p><strong>Conclusion:</strong> Acute cerebral infarction combined with hip fracture lead to worse neurological recovery, prolonged hospitalization period, increased complications, decreased patient prognosis, and increased 1 year mortality. Surgical treatment of hip fracture with concomitant acute cerebral infarction may improve the prognosis of patients. According to the statistics of neurological function and mortality after 1 year of follow-up, the prognosis of patients with Modified Rankin Scale below 3 was considered good.</p>

Abstract WP152: Novel Therapy With Pdgf-b Nanoparticles for Cerebral Infarction

Stroke ◽  
2020 ◽  
Vol 51 (Suppl_1) ◽  
Author(s):  
Soh Takagishi ◽  
Koichi Arimura ◽  
Katsuma Iwaki ◽  
Ataru Nishimura ◽  
Masaharu Murata ◽  
...  
Keyword(s):  
Cerebral Infarction ◽  
Infarct Volume ◽  
Neuroprotective Effect ◽  
Reperfusion Therapy ◽  
Artery Occlusion ◽  
Neurological Function ◽  
Novel Therapy ◽  
Infarct Area ◽  
Neurotrophin 3 ◽  
Cerebral Artery Occlusion

Background and Purpose: Treatment for cerebral infarction beyond the indication of reperfusion therapy has not yet been established, and novel approaches are needed. It has been reported that platelet-derived growth factor (PDGF)-B played a neuroprotective role by enhancing cell survival and tissue repair for a long period after cerebral infarction in experimental animal models. However, PDGF-B is difficult to administer at effective concentrations in infarct area. In general, nanoparticles are very small and stable, making them prone to accumulation without being metabolized in infarct area. Therefore, we converted PDGF-B into nanoparticles and examined its therapeutic effect for cerebral infarction. Methods: PDGF-B nanoparticles (PDGF-B NP) and wild-type nanoparticles (wNP) were injected one day after transient middle cerebral artery occlusion (tMCAO) using the CB-17 mouse model. We analyzed temporal histological changes and neurological function recovery. Fucntional recovery was assess using Cylinder test at 3 and 7 days after the tMCAO. As for the mechanism of neuroprotective effect, phosphorylation of Akt, neurotrophin-3 (NT-3), and expression of angiogenesis were also examined in the infarct area and compared them with wNP control at 7 days after tMCAO. Result: We found that PDGF-B NP was distributed specifically in the infarct area. As compared with wNP group, PDGF-B NP group significantly suppressed cerebral infarct volume and improved neurological function at 3 and 7 days after cerebral infarction compared with wNP group. Akt was strongly phosphorylated in the infarction area with PDGF-B NP administration compared with wNP. Moreover, PDGF-B NP significantly induced angiogenesis, NT-3 expression, and reduced cell apoptosis after cerebral infarction compared with wNP. Conclusion: PDGF-B NP activated PDGF-B-Akt signaling in infarct area and played various important roles leading to neuroprotection after cerebral infarction. Our results suggested that treatment with PDGF-B NP may be useful for cerebral infarction beyond reperfusion therapy.

scholarly journals Alteplase improves acute cerebral infarction by improving neurological function and cerebral hemodynamics

All Life ◽  
2021 ◽  
Vol 14 (1) ◽  
pp. 187-194
Author(s):  
Jibo Zhao ◽  
Yao Sun ◽  
Yanyu Fang ◽  
Xiaokai Liu ◽  
Fangchao Ji ◽  
...  
Keyword(s):  
Cerebral Infarction ◽  
Cerebral Hemodynamics ◽  
Neurological Function ◽  
Acute Cerebral Infarction

scholarly journals Effects of Intravenous Thrombolytic Therapy with Alteplase on Neurological Function, Coagulation Function and Serum Inflammatory Factors in Patients with Acute Cerebral Infarction

2020 ◽  
Vol 4 (3) ◽  
Author(s):  
Xianfang Yue ◽  
Hua Zhou
Keyword(s):  
Cerebral Infarction ◽  
Intravenous Thrombolysis ◽  
Neurological Function ◽  
Acute Cerebral Infarction ◽  
Inflammatory Factors ◽  
Control Group ◽  
Routine Treatment ◽  
Coagulation Function ◽  
Hs Crp ◽  
Thrombolysis Therapy

Objective: To investigate the effects of intravenous thrombolysis therapy with alteplase on neurological function, coagulation function and serum inflammatory factors in patients with acute cerebral infarction. Methods: A total of 96 patients with acute cerebral infarction admitted to our hospital from September 2017 to October 2019 were randomly divided into two groups, with 48 patients in each group. The control group (n=48) received routine treatment, and the observation group received intravenous thrombolysis therapy with alteplase on the basis of routine treatment. The neurological deficit score, prothrombin time(PT), activated partial thromboplastin time (APTT), tumor necrosis factor-a level (TNF-?), and high-sensitivity C-reactive protein (hs-CRP) were compared between the two groups after 15 days of treatment. Results: After treatment, NIHSS scores in both groups were lower than those before treatment; PT levels were increased, while APTT, TNF-? and hs-CRP levels were all decreased in both groups, and the changes in the observation group were greater than those in the control group, with statistically significant difference (P<0.05). Conclusions: Intravenous thrombolysis therapy with alteplase can improve the neurological function, coagulation function and serum levels of inflammatory factors in patients with acute cerebral infarction, which is worthy of clinical application.

Sign in / Sign up

Export Citation Format

Share Document