scholarly journals Application of diphenydramine ointment to the eyelids for allergic conjunctivitis

2021 ◽  
Vol 3 (1) ◽  
pp. 44-50
Author(s):  
Mitsuhiro Kamimura ◽  
◽  
Takako Ohnishi ◽  
Hisao Terada ◽  
Atsuto Mouri ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Visual Acuity ◽  
Intraocular Pressure ◽  
Visual Analogue Scale ◽  
Analogue Scale ◽  
Allergic Conjunctivitis ◽  
Adverse Reactions ◽  
Eye Drops ◽  
Local Skin

Introduction: Allergic conjunctivitis is treated with oral anti-allergy agents or topical eye drops, but the response is often incomplete, and symptoms persist. We considered that topical treatment with an antihistamine ointment (diphenhydramine-Restamin Cream®) on the eyelids could be effective as supplemental therapy. This study investigates the efficacy and safety of Restamin Cream® for allergic conjunctivitis. Methods: In patients with allergic conjunctivitis, Restamin Cream® was applied to both eyelids twice a day for 2 weeks. There was a 2-week observation period before treatment and a 2-week washout period after treatment. Patients recorded symptoms (eye itching and watering) on a visual analogue scale for the entire 6-week period. Assessment of quality of life, evaluation of conjunctivitis, and measurement of visual acuity and intraocular pressure were conducted at the start of observation, at initiation of treatment, at completion of treatment, and at the end of washout. Results: 7 patients were enrolled; 5 completed the study and 2 discontinued due to adverse reactions. The quality of life score and objective ocular findings improved in all 5 patients. Visual analogue scale scores for itching and watering also improved significantly in 3 and 2 patients, respectively. Adverse reactions included local skin irritation in 3/7 patients, and transient blurred vision and eye pain in 1 patient each. There were no changes of visual acuity or intraocular pressure. Conclusions: Application of diphenhydramine ointment to the eyelids was effective for allergic conjunctivitis.

Psychosocial indicators of primary congenital glaucoma and filtering surgeries impacts on children and family’s quality of life

2021 ◽  
pp. 112067212110483
Author(s):  
Andrea Oliveira da Silva ◽  
Christiane Rolim-de-Moura ◽  
Nara Lúcia Poli Botelho ◽  
Carolina PB Gracitelli ◽  
Nívea Nunes Ferraz
Keyword(s):  
Quality Of Life ◽  
Visual Acuity ◽  
Intraocular Pressure ◽  
Surgical Treatment ◽  
Optic Disk ◽  
Congenital Glaucoma ◽  
Eye Drops ◽  
Primary Congenital Glaucoma ◽  
Corneal Diameter

Purpose: To identify psychosocial indicators and evaluate the filtering surgeries impacts on quality of life (QOL) of children with primary congenital glaucoma (PCG) and their family. Methods: Parents of children with bilateral PCG who underwent filtering surgery were included. Data were collected through: (a) psychological inquiry to determine psychosocial indicators; (b) Children’s Visual Function Questionnaire (CVFQ). The associations between the CVFQ scores and visual acuity, intraocular pressure, optic disk cupping, horizontal corneal diameter, axial length, number of surgeries, and hypotensive eye drops were investigated. The statistical significance level was considered as p ⩽ 0.05. Results: The mean age of the nine mothers interviewed and their children (six boys and three girls) was 29 ± 5 years and 35 ± 18 months, respectively. The psychosocial indicators determined were: emotional impact of the diagnosis, disease knowledge, mother and family’s feelings on facing the surgical treatment, surgical result comprehension, treatment adherence, child's emotional and behavioral reactions, social support, and future expectations. In CVFQ analysis, QOL score was strongly associated with visual acuity ( r = −0.79; p = 0.01). Besides the treatment score was correlated to intraocular pressure ( r = −0.68; p < 0.05), optic disk cupping ( r = −0.85; p = 0.03), and corneal diameter ( r = −0.69; p = 0.02). Correlations were not found for number of surgeries and eye drops. Conclusions: This study confirmed the PCG surgical treatment impact on QOL and determined psychosocial indicators which may favor the suitable actions in psychological treatment and follow-up of the children and families.

scholarly journals The effect of the main active substances of antihypertensive eye drops on condition of the eyes of glaucoma patients

2020 ◽  
pp. 5-10
Author(s):  
O. N. Onufriichuk ◽  
I. R. Gazizova ◽  
A. V. Kuroyedov ◽  
A. V. Seleznev
Keyword(s):  
Quality Of Life ◽  
Adverse Reactions ◽  
Hypotensive Effect ◽  
Eye Drops ◽  
Common Cause ◽  
Treatment Regimens ◽  
Active Substances ◽  
Lifetime Treatment

Today, glaucoma is considered to be the most common cause of irreversible blindness. The treatment of this disease is aimed at reducing intraocular tension in order to slow down the deterioration of visual functions and to maintain accept‑ able quality of life. Most ophthalmologists prefer local medicamentous therapy. Despite a significant expansion of the range of antihypertensive medicines, a significant increase in the hypotensive effect is not always achieved in each certain case, at the same time, at long-term (sometimes lifetime) treatment local and systemic adverse reactions arise and intensify. The findings of recent clinical trials presented in this overview demonstrate an adverse effect of active compounds, preservatives and ad‑ ditives of ophthalmic medicines not only on the eye surface but also on the structure of anterior and posterior eye segments. Taking into account possible side effects of each component of medicines used in glaucoma therapy, ophthalmologists will be able to reasonably approach the choice of optimal treatment regimens with the lowest risk for patients.

scholarly journals Efektivitas imunoterapi terhadap gejala, temuan nasoendoskopik dan kualitas hidup pasien rinosinusitis alergi

2012 ◽  
Vol 42 (2) ◽  
Author(s):  
Yuwan Pradana ◽  
Teti Madiadipoera ◽  
Melati Sudiro ◽  
Arif Dermawan
Keyword(s):  
Quality Of Life ◽  
Visual Analogue Scale ◽  
Disease Severity ◽  
Analogue Scale ◽  
Specific Immunotherapy ◽  
Drug Intake ◽  
Allergen Specific Immunotherapy ◽  
Nasal Symptoms ◽  
Severity Of The Disease

Background: Rhinosinusitis is one of major health problems which increased the economic burden. With symptoms include nasal congestion, rhinorrhea, facial pain, and sometimes reduced or loss of smell, this condition may impair work productivity and quality of life (QOL). Rhinosinusitis is one of the comorbidity of allergic rhinitis. Allergen specific immunotherapy provides protection against the occurence of allergic symptoms and inflammatory reactions due to allergen exposure, that results in improvement  of QOL of allergic rhinosinusitis patients.   To assess the effectiveness of immunotherapy in the  severity of the disease, nasal symptoms, nasoendoscopic findings, drugs intake, and the QOL in allergic rhinosinusitis patients treated with specific immunotherapy. Methods: A retrospective descriptive study conducted at the Rhinology-Allergy Clinic of ORL-HNS Department, Dr.Hasan Sadikin General Hospital, Bandung, on January - December 2011, towards 25 patients, by anamnesis, severity of the disease using Visual Analogue Scale (VAS), nasal symptoms from Weeke, Davis and Okuda, nasoendoscopic findings from Lund-Kennedy, drug intake score, and QOL assesment using Rhinoconjuctivitis Quality of Life Questionaire. Results: There was a significant correlation (p<0,05) between specific immunotherapy for 1 year observed by reduced disease severity, reduced nasal symptoms, nasoendoscopic findings improvement, reduced drug intake, and increased Quality of Life which shows significant results from 3 months after immunotherapy using Wilcoxon differential test (p<0,001). Conclusion: Immunotherapy for 1 year was significantly reduced disease severity, reduced nasal symptoms, improved nasoendoscopic findings, reduced drug intake, and improvement of QOL in patients with allergic rhinosinusitis began from 3 months after immunotherapy and maintained afterwards. Key words: allergic rhinosinusitis, nasal symptoms, nasoendoscopy, specific immunotherapy, quality of life    Abstrak :  Latar belakang: Rinosinusitis merupakan salah satu masalah kesehatan yang semakin meningkat sehingga menjadi beban besar terhadap perekonomian masyarakat. Dengan gejala berupa hidung tersumbat, rinore, nyeri pada wajah dan dapat disertai berkurang atau hilangnya penciuman, kondisi ini dapat menurunkan produktivitas kerja dan kualitas hidup. Rinosinusitis merupakan salah satu komorbiditas dari rinitis alergi. Imunoterapi alergen spesifik bertujuan untuk memberikan perlindungan terhadap timbulnya gejala alergi dan reaksi inflamasi akibat pajanan alergen, sehingga dapat meningkatkan kualitas hidup pasien rinosinusitis. Tujuan: Membuktikan efektivitas imunoterapi terhadap tingkat beratnya penyakit, gejala hidung, nasoendoskopi, penggunaan obat dan kualitas hidup pasien rinosinusitis alergi yang diberikan pengobatan imunoterapi selama 3, 6, dan 12 bulan. Metode: Dilakukan penelitian deskriptif retrospektif, di Poliklinik Rinologi Alergi Ilmu Kesehatan THT-KL RSHS Bandung, dalam periode JanuariDesember 2011 pada 25 pasien, menggunakan anamnesis, tingkat berat penyakit berdasarkan Visual Analogue Scale (VAS), gejala hidung  berdasarkan Weeke, Davis dan Okuda, pemeriksaan nasoendoskopi berdasarkan Lund-Kennedy, penggunaan obat dan penilaian kualitas hidup dengan Rhinoconjuctivitis Quality of Life Questionaire. Hasil: Didapatkan hubungan bermakna berdasarkan uji chi-kuadrat-Friedman   antara imunoterapi selama 1 tahun (p<0,05) terhadap penurunan tingkat berat penyakit, penurunan gejala hidung, perbaikan temuan nasoendoskopi, penurunan penggunaan obat, serta peningkatan kualitas hidup. Didapat perbaikan secara bermakna sejak 3 bulan pasca imunoterapi (p<0,001) berdasarkan uji beda Wilcoxon. Kesimpulan: Imunoterapi selama 1 tahun efektif terhadap penurunan tingkat berat penyakit, penurunan gejala hidung, perbaikan temuan nasoendoskopi, penurunan penggunaan obat, serta peningkatan kualitas hidup pada pasien rinosinusitis alergi, dengan perbaikan sejak 3 bulan dan bertahan hingga 1 tahun pasca-imunoterapi. Kata kunci: rinosinusitis alergi, gejala hidung, nasoendoskopi, imunoterapi, kualitas hidup 

Comparison of an epicondylitis bandage with a wrist orthosis in patients with lateral epicondylitis

2018 ◽  
Vol 42 (6) ◽  
pp. 599-605 ◽  
Author(s):  
Halil Ekrem Akkurt ◽  
Hilal Kocabaş ◽  
Halim Yılmaz ◽  
Cemile Eser ◽  
Zafer Şen ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Muscle Strength ◽  
Visual Analogue Scale ◽  
Functional Status ◽  
Effective Treatment ◽  
Analogue Scale ◽  
Short Form ◽  
Treatment Options ◽  
Lateral Epicondylitis

Background: Lateral epicondylitis is one of the most common causes of elbow pain. It is generally observed in people between the ages of 40 and 50 years, and the dominant extremity is more frequently affected. Various noninvasive methods are frequently used; however, studies investigating the effectiveness of the orthoses are limited and with controversial outcomes. Objective: To investigate the effectiveness of a hand-wrist resting orthosis and an epicondylitis bandage in lateral epicondylitis. Study design: Randomized controlled trial. Methods: In total, 82 patients diagnosed with unilateral lateral epicondylitis were enrolled into the study. Hand-wrist resting orthosis was applied to 45 patients and epicondylitis bandage was applied to 41 patients. Patients were evaluated before treatment and at 6 weeks after treatment with a Visual Analogue Scale; Disabilities of the Arm, Shoulder, and Hand questionnaire; the Short Form 36; and a determination of hand grasping force. Results: Both groups were similar in terms of age, body mass index, gender, frequency of lateral epicondylitis on the dominant side, dominant extremity, and duration of complaints ( p > 0.05). A statistically significant recovery was detected in both groups between the pre-therapy values and the values at the sixth week in terms of Visual Analogue Scale scores; Disabilities of the Arm, Shoulder, and Hand questionnarie scores; hand grasping forces; and the Short Form 36 mental and physical component scores ( p < 0.05). However, there were no significant differences detected between the two therapy methods before the therapy and at the sixth week of treatment in all parameter values ( p > 0.05). Conclusion: Our results suggest that both epicondylitis bandage and hand-wrist resting orthosis are effective treatment options for lateral epicondylitis–induced pain, functional status, muscle strength, and quality of life. Furthermore, neither treatment option was superior to the other. Large, randomized studies are necessary for more clear statements. Clinical relevance Epicondylitis bandage and hand-wrist resting orthosis are equally effective treatment options for lateral epicondylitis–induced pain, functional status, muscle strength, and quality of life.

scholarly journals Applicazione della sulfadiazina argentica 1% in crema per il trattamento e la prevenzione delle infezioni nelle ulcere croniche degli arti inferiori/Use of silver sulfadiazine 1% cream for the treatment and prevention of infected chronic leg ulcers

2019 ◽  
Vol 3 (2) ◽  
Author(s):  
Francesco Giacinto ◽  
Elisabetta Giacinto ◽  
Mario Giacinto ◽  
Filomena Casciani ◽  
Domenica Ciuffoletti
Keyword(s):  
Quality Of Life ◽  
Visual Analogue Scale ◽  
Analogue Scale ◽  
Skin Lesions ◽  
Silver Sulfadiazine ◽  
Leg Ulcers ◽  
Systemic Antibiotic Therapy ◽  
Quality Of Life Scale ◽  
Life Scale

Il trattamento delle lesioni cutanee è complesso per la varietà delle eziologie, della presentazione della ferita, del decorso e delle elevate comorbidità associate. La risoluzione di un’eventuale infezione, che rappresenta la condizione indispensabile per la successiva guarigione della lesione, è da considerarsi l’obiettivo primario di qualsiasi intervento. Numerose sono le evidenze presenti in letteratura che attestano la superiorità di un trattamento antibiotico topico rispetto a una terapia antibiotica sistemica in presenza di una ferita infetta. È stato evidenziato come la sulfadiazina argentica 1% crema (SSD Ag 1%), un antibiotico chemioterapico topico, sia efficace nella prevenzione e cura delle lesioni cutanee acute e croniche infette e/o suscettibili di superinfezioni. Lo scopo di questo studio è quello di verificare l’efficacia della SSD nel migliorare la qualità di vita di pazienti affetti da lesioni. La ricerca è stata condotta presso l’Ambulatorio sperimentale di Vulnologia nel CAPT di Praia a Mare (ASP Cosenza, Italia); ha coinvolto 86 pazienti nell’arco di 4 mesi, trattati in parte in ambulatorio ed in parte in assistenza domiciliare, con età media di 69,6 anni, per la profilassi (50/86, 58%) o per il trattamento (36/86, 42%) di ulcere interessanti principalmente gli arti inferiori. I risultati ottenuti dall’utilizzo della SSD Ag 1% hanno evidenziato che, nei pazienti in cui il prodotto è stato applicato come trattamento, la percezione del dolore è diminuita in 18 su 24 pazienti, con un’aumentata qualità di vita valutata attraverso la Visual Analogue Scale-Quality of Life Scale. L’efficacia della SSD Ag 1% è stata dimostrata dai 23 casi di guarigione in 12 settimane e dai 5 casi in 4 settimane e dai 10 casi di risoluzione della sola infezione. La SSD Ag% si dimostra essere un ottimo prodotto sia per la profilassi (per prevenire l’insorgenza dell’infezione nelle ulcere a rischio) che per il trattamento dell’infezione delle ferite, coniugando efficacia e tollerabilità. Treating skin lesions is complex due to the variety of aetiologies, the presentation of the wound, the course of the injury and the high number of associated comorbidities. The main aim of any treatment is to resolve any infection, as this is the essential condition for the lesion to subsequently heal. There is a lot of evidence in literature that a topical antibiotic treatment is better than a systemic antibiotic therapy for infected wounds. Silver sulfadiazine 1% cream (SSD Ag 1%), a topical chemotherapy antibiotic, has been proved to be effective for the prevention and cure of acute and chronic skin lesions that are infected or susceptible to superinfection. The purpose of this study is to confirm the efficacy of SSD Ag 1%in improving the quality of life of patients with lesions. The study was conducted at the Experimental Wound Treatment Outpatients Department of the Praia a Mare Local Healthcare Centre (Cosenza Health Authority, Italy); it involved 86 patients during a 4-month period, some of whom were treated in the outpatients department and some at home, with an average age of 69.6, for prophylaxis (50/86, 58%) or to treat ulcers, primarily leg ulcers (36/86, 42%). The results of using SSD Ag 1% cream showed that for patients on whom the product was used as treatment, pain perception fell in 18 out of 24 patients, with improved quality of life assessed using the Visual Analogue Scale-Quality of Life Scale. The efficacy of SSD Ag 1% was shown by 23 cases of healing in 12 weeks and 5 cases in 4 weeks and by 10 cases of resolution of the infection only. SSD Ag 1% was shown to be an excellent product both for prophylaxis (to prevent infections in high-risk ulcers) and for treating wound infections, combining efficacy and tolerability.

Is a single-item visual analogue scale as valid, reliable and responsive as multi-item scales in measuring quality of life?

2004 ◽  
Vol 13 (2) ◽  
pp. 311-320 ◽  
Author(s):  
A.G.E.M. de Boer ◽  
J.J.B. van Lanschot ◽  
P.F.M. Stalmeier ◽  
J.W. van Sandick ◽  
J.B.F. Hulscher ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Visual Analogue Scale ◽  
Analogue Scale ◽  
Single Item

scholarly journals Treatment restrictions in patients with severe stroke are associated with an increased risk of death

2017 ◽  
Vol 2 (3) ◽  
pp. 244-249 ◽  
Author(s):  
Marjolein Geurts ◽  
Floor AS de Kort ◽  
Paul LM de Kort ◽  
Julia H van Tuijl ◽  
Ghislaine JMW van Thiel ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Visual Analogue Scale ◽  
Functional Outcome ◽  
Analogue Scale ◽  
Modified Rankin Scale ◽  
Severe Stroke ◽  
Risk Of Death ◽  
Increased Risk ◽  
Treatment Restrictions

Introduction Treatment restrictions in the first 2 days after intracerebral haemorrhage have been independently associated with an increased risk of early death. It is unknown whether these restrictions also affect mortality if these are installed several days after stroke onset. Patients and methods Sixty patients with severe functional dependence at day 4 after ischaemic stroke or intracerebral haemorrhage were included in this prospective two-centre cohort study. The presence of treatment restrictions was assessed at the day of inclusion. Information about mortality, functional outcome (modified Rankin scale) score and quality of life (visual analogue scale) was recorded 6 months after stroke onset. Poor outcome was defined as modified Rankin scale >3. Satisfactory quality of life was defined as visual analogue scale ≥ 60. Results At 6 months, 30 patients had died, 19 survivors had a poor functional outcome and 9 patients had a poor quality of life. Treatment restrictions were independently associated with mortality at 6 months (adjusted relative risk, 1.30; 95% confidence interval, 1.06–1.59; p = 0.01), but not with functional outcome. Discussion Our findings were observed in 60 selected patients with severe stroke. Conclusion The instalment of treatment restrictions by itself may increase the risk of death after stroke, even if the first 4 days have passed. In future stroke studies, this potential confounder should be taken into account. Quality of life was satisfactory in the majority of the survivors, despite considerable disability.

Well-being and belief in a just world among rest home residents

2011 ◽  
Vol 39 (5) ◽  
pp. 655-670 ◽  
Author(s):  
Ramzi Nasser ◽  
Jacqueline Doumit ◽  
James Carifio
Keyword(s):  
Quality Of Life ◽  
Visual Analogue Scale ◽  
Analogue Scale ◽  
Well Being ◽  
Just World ◽  
Rest Home ◽  
Main Effects ◽  
The Relationship ◽  
Eq Vas

Several theorists have contended that belief in a just world may be one way elderly rest home residents cope with anxiety, fear, and depression and thus maintain their well-being. In this study we explored belief in a just world and length of time elderly have been residing in rest homes in Lebanon in relation to their levels of self-rated quality of life. A sample of 354 cognitively able elderly people were selected from 36 nursing homes. Interview questionnaires including a translated and validated Self-beliefs in a Just World Scale (BJW-S; Lipkus, Dalbert, & Siegler, 1996) and the EuroQol Visual Analogue Scale (EQ-VAS; Brooks, 1996) that measures respondents' quality of life on a 20cm visual analogue scale. The relationship between Arabic BJW-S scores and length of stay measured on the EQ-VAS was examined using analysis of variance. The findings showed significant main effects for belief in a just world on levels of EQ-VAS, but no significant effects of length of time in rest home on levels of EQ-VAS. Residents who had strong beliefs in a just world seem to have better abilities to cope with negative life events and better self-rated feelings of well-being than did residents who did not believe the world was just and who rated their own well-being lower.

scholarly journals Depression in elderly patients with Alzheimer dementia or vascular dementia and its infl uence on their quality of life

2011 ◽  
Vol 02 (01) ◽  
pp. 027-032 ◽  
Author(s):  
Yaroslav Winter ◽  
Alexei Korchounov ◽  
Tatyana V Zhukova ◽  
Natalia Epifanova Bertschi
Keyword(s):  
Quality Of Life ◽  
Cognitive Impairment ◽  
Visual Analogue Scale ◽  
Vascular Dementia ◽  
Analogue Scale ◽  
Depression Scale ◽  
Alzheimer Dementia ◽  
Co Morbidity ◽  
Prevalence Of Depression

ABSTRACT Background: Alzheimer dementia (AD) and vascular dementia (VD) are the most common causes of dementia in the elderly. Depression is an important co-morbid disorder in these diseases, which is often challenging to recognize. We investigated the prevalence of depression in patients with AD and VD and estimated the influence of depression on the health-related quality of life (HrQoL) in these patients. Materials and Methods: We evaluated prevalence of depression in consecutively recruited patients with AD or VD (n= 98). Depression was diagnosed according to criteria of the Diagnostic and Statistical Manual of Mental Disorders (DSM-IV) and scored using the Geriatric Depression Scale. The EuroQol (EQ-5D and visual analogue scale) was applied to evaluate HrQoL. The severity of cognitive impairment was measured by the Mini-Mental State Examination (MMSE). Multiple regression analysis was used to identify factors predicting severity of depression. Results: The prevalence of depression in AD/VD was 87%. In comparison to the general population, HrQoL measured on the visual analogue scale was reduced by 54% in patients with AD/VD. In the dimension “anxiety/depression” of the EQ-5D, 81% of patients with AD/VD had moderate or severe problems. Depression showed significant association with reduced HrQoL (P < 0.01). Independent predictors of more severe depression were older age, male gender, better MMSE scores and being not married. Conclusions: Depression is a prevalent psychiatric co-morbidity in patients with AD/VD, which is often under-diagnosed being masked by cognitive impairment. Depression is a predictor of reduced HrQoL in elder people with AD/VD. Therefore, they should be screened for presence of depressive symptoms and receive adequate antidepressant treatment.

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