scholarly journals Regional Variation on Rates of Bronchopulmonary Dysplasia and Associated Risk Factors

2012 ◽  
Vol 2012 ◽  
pp. 1-9 ◽  
Author(s):  
María Ximena Rojas ◽  
Mario Augusto Rojas ◽  
Juan Manuel Lozano ◽  
Martín Alonso Rondón ◽  
Laura Patricia Charry
Keyword(s):  
Risk Factors ◽  
Bronchopulmonary Dysplasia ◽  
Management Practices ◽  
Population Characteristics ◽  
Disease Rates ◽  
Respiratory Management ◽  
High Incidence ◽  
Traditional Risk Factors ◽  
Associated Risk Factors ◽  
Control Study

Background. An abnormally high incidence (44%) of bronchopulmonary dysplasia with variations in rates among cities was observed in Colombia among premature infants. Objective. To identify risk factors that could explain the observed high incidence and regional variations of bronchopulmonary dysplasia. Study Design. A case-control study was designed for testing the hypothesis that differences in the disease rates were not explained by differences in city-of-birth specific population characteristics or by differences in respiratory management practices in the first 7 days of life, among cities. Results. Multivariate analysis showed that premature rupture of membranes, exposure to mechanical ventilation after received nasal CPAP, no surfactant exposure, use of rescue surfactant (instead of early surfactant), PDA, sepsis and the median daily FIO2, were associated with a higher risk of dysplasia. Significant differences between cases and controls were found among cities. Models exploring for associations between city of birth and dysplasia showed that being born in the highest altitude city (Bogotá) was associated with a higher risk of dysplasia (OR 1.82 95% CI 1.31–2.53). Conclusions. Bronchopulmonary dysplasia was manly explained by traditional risk factors. Findings suggest that altitude may play an important role in the development of this disease. Prenatal steroids did not appear to be protective at high altitude.

The Use of Dexamethasone in Premature Infants at Risk for Bronchopulmonary Dysplasia or Who Already Have Developed Chronic Lung Disease: A Cautionary Note

PEDIATRICS ◽  
1991 ◽  
Vol 88 (2) ◽  
pp. 413-414
Author(s):  
LEE FRANK
Keyword(s):  
Risk Factors ◽  
Bronchopulmonary Dysplasia ◽  
Animal Studies ◽  
Very Low Birth Weight ◽  
Double Blind Study ◽  
Dexamethasone Treatment ◽  
Double Blind ◽  
High Incidence ◽  
Potential Risk Factors ◽  
Clinical Problems

To the Editor.— The distressingly high incidence of bronchopulmonary dysplasia (BPD) in today's very low birth weight premature infant population and the prolonged morbidity and tumultuous clinical problems associated with BPD in these tiny infants have led to a trial usage of dexamethasone treatment to try to assuage these problems in this patient population. The report of Kazzi et al1 is noteworthy because the authors not only indicate in clear fashion the failure of relatively prolonged dexamethasone treatment to ameliorate the hospital course of infants with BPD (in a randomized prospective double-blind study), but they also clearly identify potential risk factors associated with dexamethasone treatment that are of concern to them as clinical investigators, risk factors based both on clinical and experimental animal studies.

Malnutrition Concerning Geriatric Depression and Associated Risk Factors: A Community-based Case-control Study in Rural Elderly of Bangladesh

2020 ◽  
Author(s):  
Md Ziaul Islam ◽  
Tasnim Disu ◽  
Shatmin Farjana ◽  
Mohammad Rahman
Keyword(s):  
Risk Factors ◽  
Case Control Study ◽  
The Elderly ◽  
Case Control ◽  
Rural Elderly ◽  
Geriatric Depression ◽  
Elderly Individuals ◽  
Significant Difference ◽  
Associated Risk Factors ◽  
Control Study

Abstract Background: Malnutrition and depression are highly prevalent in the elderly and can lead to disparaging outcomes. Analytical studies on malnutrition concerning geriatric depression (GD) are very scarce in Bangladesh, although the size of the elderly population is increasing fast in the country. The current study aimed to assess the association between malnutrition and depression and associated risk factors in the rural elderly.Methods: A case-control study was conducted in 600 elderly residents (aged ≥60 years) of three rural communities of Bangladesh from January to October 2019. Three hundred depressed elderly people were enrolled as cases and 300 non-depressed elderly individuals were included as community controls by matching the age and living area of the cases. We used a semi-structured questionnaire based on the Geriatric Depression Scale-15 and the Bangla version of Mini-Nutritional Assessment-Short Form to collect data through face-to-face interviews. Measures included baseline and personal characteristics, malnutrition, GD, and associated risk factors. A binary logistic regression model was fitted to identify variables associated with the risk of GD.Results: The study found no significant difference in gender (male Vs. female) between cases (44.0% Vs. 56.0%) and controls (46.0% Vs. 54.0%). The study revealed that malnutrition was significantly (p<0.01) higher in cases (56.0%) than in controls (18.0%). The malnourished elderly had around three times AOR=3.155; 95% CI: 1.53-6.49, p=0.002) more (risk of having depression than the controls. The unemployed elderly (AOR=4.964; 95% CI: 2.361-10.440; p=0.0001) and the elderly of the lower and middle class (AOR=3.654; 95% CI: 2.266-7.767; p=0.001) were more likely to experience depression. The elderly having a poor diet were more likely to experience depression (AOR=3.384; 95% CI: 1.764-6.703; p=0.0001). The single elderly (AOR=2.368; 95% CI: 1.762-6.524; p=0.001) and the elderly tobacco users (AOR=2.332; 95% CI: 1.663-5.623; p=0.003) were more likely to experience depression.Conclusions: A significant association between malnutrition and depression is evident in the rural elderly individuals of Bangladesh. It will be a prolific initiative if policymakers merge malnutrition and the risk factors associated with geriatric depression in the provision of universal health care for better health and well-being of the rural elderly populations.

scholarly journals Serum Paraoxonase (Arylesterase) Activity in Chronic Renal Failure

2011 ◽  
Vol 12 (1) ◽  
pp. 17-20
Author(s):  
Balasubramaniam Gayathri ◽  
Anand Usha ◽  
Duraisamy Vijaya
Keyword(s):  
Risk Factors ◽  
Renal Failure ◽  
Chronic Renal Failure ◽  
Predictive Accuracy ◽  
Background Mortality ◽  
Anti Oxidant ◽  
Traditional Risk Factors ◽  
Artery Disease ◽  
Serum Paraoxonase ◽  
Control Study

Background: Mortality rates are higher among patients with chronic renal failure with a good proportion of this excess burden being attributable to cardiovascular disease. This excess risk is not entirely explained by elevated traditional risk factors. Among the non-traditional risk factors, serum paraoxonase (Arylesterase) activity is an important one. Materials and Methods: It was a case-control study which included total 127 subjects, 44 were non-dialysis CKD patients, 33 Heamodialysis dependent patients and 50 healthy controls. HDL-C, Apo-A and serum paraoxonase (Arylesterase) activity was estimated and compared with normal control population. Results: Serum Arylesterase activity, a measure of PON was significantly lower in CRF (on conservative management and on hemodialysis) compared to controls. Conclusion: Measurement of anti oxidant capacity of HDL-C may improve the predictive accuracy of atherosclerotic coronary artery disease, providing new strategies for the prevention and treatment of accelerated atherosclerosis in chronic renal failure. Keyword: Serum paraoxonase (Arylesterase); chronic renal failure; AtherosclerosisDOI: 10.3329/jom.v12i1.5638J Medicine 2011; 12 : 17-20

Risk factors in lateral epicondylitis (tennis elbow): a case-control study

2012 ◽  
Vol 38 (2) ◽  
pp. 159-164 ◽  
Author(s):  
A. G. Titchener ◽  
A. Fakis ◽  
A. A. Tambe ◽  
C. Smith ◽  
R. B. Hubbard ◽  
...  
Keyword(s):  
Risk Factors ◽  
Case Control Study ◽  
Tennis Elbow ◽  
Lateral Epicondylitis ◽  
Case Control ◽  
Smoking History ◽  
Health Improvement ◽  
Tunnel Syndrome ◽  
Associated Risk Factors ◽  
Control Study

Lateral epicondylitis is a common condition, but relatively little is known about its aetiology and associated risk factors. We have undertaken a large case-control study using The Health Improvement Network database to assess and quantify the relative contributions of some constitutional and environmental risk factors for lateral epicondylitis in the community. Our dataset included 4998 patients with lateral epicondylitis who were individually matched with a single control by age, sex, and general practice. The median age at diagnosis was 49 (interquartile range 42–56) years . Multivariate analysis showed that the risk factors associated with lateral epicondylitis were rotator cuff pathology (OR 4.95), De Quervain’s disease (OR 2.48), carpal tunnel syndrome (OR 1.50), oral corticosteroid therapy (OR 1.68), and previous smoking history (OR 1.20). Diabetes mellitus, current smoking, trigger finger, rheumatoid arthritis, alcohol intake, and obesity were not found to be associated with lateral epicondylitis.

Psoriasis in France and Associated Risk Factors: Results of a Case-Control Study Based on a Large Community Survey

Dermatology ◽  
2008 ◽  
Vol 218 (2) ◽  
pp. 103-109 ◽  
Author(s):  
P. Wolkenstein ◽  
J. Revuz ◽  
J.C. Roujeau ◽  
G. Bonnelye ◽  
J.J. Grob ◽  
...  
Keyword(s):  
Risk Factors ◽  
Case Control Study ◽  
Case Control ◽  
Community Survey ◽  
Large Community ◽  
Associated Risk Factors ◽  
Control Study

scholarly journals Fore-Stomach Foreign Bodies: prevalence, associated risk factors and types affecting cattle slaughtered at Gondar ELFORA abattoir, northwest Ethiopia

2020 ◽  
Vol 24 (2) ◽  
pp. 112-122
Author(s):  
Amare Bihon ◽  
Teketaye Bayeleyegn ◽  
Ayalew Assefa ◽  
Yimer Muktar
Keyword(s):  
Risk Factors ◽  
Foreign Body ◽  
Management Practices ◽  
Foreign Bodies ◽  
Cross Sectional Study ◽  
Northwest Ethiopia ◽  
Solid Waste Disposal ◽  
Cross Sectional ◽  
Adult Cattle ◽  
Associated Risk Factors

In Ethiopia, recurrent drought and feed shortage coupling with high level of environmental pollution predispose the animals to foreign body  ingestion. A cross-sectional study with systematic random sampling approach was employed from November 2018 to April, 2019 with the objectives of estimating the prevalence; identify associated risk factors and to categorize the types of foreign body in cattle slaughtered at Gondar ELFORA Abattoir. Ante-mortem and postmortem examinations were used to collect the data. From the total of 384 animals examined, the overall prevalence of foreign body was 83(21.61%). Adult and old animals were 4.33 (95% CI=0.98, 19.00, p=0.052) and 4.54 (95% CI=1.03, 19.96, p=0.045) times more likely to have a chance of getting foreign body than young animals by keeping another factors constant, respectively. However, the difference is not statistically significant for adult cattle. Moreover, poor and medium body conditioned animals were 2.19 (95% CI=1.04, 4.56, p=0.037) and 1.51 (95% CI=0.72, 3.13, p=0.273) times more likely to acquire foreign bodies than good body conditioned animals by keeping another factors constant. In the positive cases (N=83), 41(49.40%), 34(40.96%), 8(9.64%) and 0(0%) of the foreign bodies were found in the rumen, reticulum, both rumen and reticulum, and omasum, respectively. Majority of foreign bodies identified (79.51%) were non-metallic in nature, including clothes, plastics, rope,  sand and stone. Designing and implementation of appropriate solid waste disposal and management practices are strongly recommended to reduce the risk of ingestion of indigestible foreign bodies. Keyword: Abattoir; Cattle; Foreign body; Fore stomach; Prevalence

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