scholarly journals Imaging finding in diabetic mastopathy: A case report

2018 ◽  
Vol 5 (2) ◽  
pp. 19
Author(s):  
Lynda Nadine Gui Bile ◽  
Hanane Antoun ◽  
Judicael Ahoury ◽  
Raissa Kabas ◽  
Estelle Valerie Ohui-Acko ◽  
...  

Diabetic mastopathy is an uncommon immunologic breast disease occurring usually in patients under long-term insulin treatment. It can pose a question of differential diagnosis with breast cancer especially in case of family history of breast cancer. We report the radiological diagnostic approach of a case of diabetic mastopathy with family history of breast cancer. The mammogram was nonspecific. Ultrasound showed two suspicious masses of right breast without suspicious enhancement on MRI. Diabetic mastopathy was confirmed on histology without cancer cells. Diabetic mastopathy is a diagnostic challenge and needs to be suspected in all patients with type I diabetes. Image-guided biopsy confirmation remains mandatory. The literature is briefly reviewed.

2021 ◽  
Vol 2021 ◽  
pp. 1-6
Author(s):  
Qasem Asgari ◽  
Mohammad Hossein Motazedian ◽  
Amir Khazanchin ◽  
Davood Mehrabani ◽  
Shahrbanou Naderi Shahabadi

Background. Type I diabetes (TΙDM) is a genetic or autoimmune disorder, which may be stimulated by induced immune system components due to the underlying infectious diseases. This study was undertaken to find out any possible association between Toxoplasma gondii infection and TIDM. Materials and Methods. One hundred and eighty-two blood samples were taken from individuals who were referred to outpatient clinics in Shiraz city, Southern Iran, during a 6-month period. The age of type I diabetic subjects ( n = 91 ) and the control group ( n = 91 ) was identical, which were less than 30 years. The sera were examined for IgG and IgM antibodies by ELISA and correlated with epidemiological factors such as age, sex, and family history of diabetes. Results. Out of 91 diabetic patients, 54 (59.3%) were female and 37 (40.7%) were male. The highest frequency of diabetes belonged to 6-10- and 11-15-year groups ( P = 0.17 ). Toxoplasma infection prevalence in diabetic and control groups was 28.6% and 7.7%, respectively ( P = 0.001 ). A significantly positive family history of diabetes was observed between diabetic patients (31 cases, 34.1%) and the control group (3 cases, 3.3%) ( P = 0.01 ). Interestingly, IgG positivity was seen in 13 cases (41.9%) of patients with positive family history of type I diabetes and 13 cases (21.7%) of subjects with no positive family history of type I diabetes ( P = 0.04 ). Conclusion. Our study showed a higher prevalence of Toxoplasma infection in type I diabetes patients. It is likely that the prevalence of TIDM decreases by increasing hygiene and preventing toxoplasmosis.


Cancer ◽  
2011 ◽  
Vol 118 (11) ◽  
pp. 2796-2803 ◽  
Author(s):  
Catherine S. Berkey ◽  
Rulla M. Tamimi ◽  
Bernard Rosner ◽  
A. Lindsay Frazier ◽  
Graham A. Colditz

1991 ◽  
Vol 95 (2) ◽  
pp. 157-165 ◽  
Author(s):  
C. Jay Marshall ◽  
G. Berry Schumann ◽  
John H. Ward ◽  
James M. Riding ◽  
Lisa Cannon-Albright ◽  
...  

2002 ◽  
Vol 100 (3) ◽  
pp. 375-378 ◽  
Author(s):  
Penelope M. Webb ◽  
Celia Byrne ◽  
Stuart J. Schnitt ◽  
James L. Connolly ◽  
Timothy Jacobs ◽  
...  

2012 ◽  
Author(s):  
Sarah Israel ◽  
Hind Warzecha ◽  
Amy L. Gross ◽  
Armanda Tatsas ◽  
Andrew Lee ◽  
...  

2018 ◽  
Vol 2018 ◽  
pp. 1-6 ◽  
Author(s):  
Laura Conti ◽  
Edith Lahner ◽  
Gloria Galli ◽  
Gianluca Esposito ◽  
Marilia Carabotti ◽  
...  

Objectives. Autoimmune diseases (AD) may be associated with coeliac disease (CD), but specific risk factors have been poorly investigated. The aim of this study was to assess the spectrum of AD and its specific risk factors associated in a series of adult coeliac patients. Materials and Methods. We performed a single-center case-control study including adult newly diagnosed CD patients. To evaluate the risk factors of the association between AD and CD, 341 coeliac patients included were categorized on the basis of AD presence: 91 cases with at least one AD and 250 controls without AD were compared for clinical, serological, and histological features. Eighty-seven cases were age-gender-matched with 87 controls. Results. Among 341 CD patients, 26.6% of CD patients had at least one AD. Endocrine and dermatological diseases were the most prevalent AD encountered: autoimmune thyroiditis was present in 48.4% of cases, psoriasis in 17.6%, and type I diabetes and dermatitis herpetiformis in 11%, respectively. At logistic regression, factors associated with AD were a positive 1st-degree family history of AD (OR 3.7, 95% CI 1.93–7), a body mass index ≥ 25 kg/m2 at CD diagnosis (OR 2.95%, CI 1.1–3.8), and long standing presentation signs/symptoms before CD diagnosis (>10 years) (OR 2.1, 95% CI 1.1–3.7). Analysis on age-gender-matched patients confirmed these results. Conclusions. CD patients with family history of AD, overweight at CD diagnosis, and a delay of CD diagnosis had an increased risk of having another AD. The benefit of CD screening in these specific subsets of patients with AD awaits further investigation.


2012 ◽  
Vol 18 (1) ◽  
pp. 13-18
Author(s):  
Irina Franciuc ◽  
Cristina Maria Mihai ◽  
Alina Martinescu ◽  
Loredana Mariana Aftenie ◽  
Adina Honcea

AbstractThe aim of this study was to present the cases with family history of type 1 diabetes in a group of pediatric patients from the Clinic of Pediatrics, Constanta County Hospital, and to analyze the risk for relatives conferred by presence of particular DR genotypes. 8 out of 60 index cases had relatives affected with type 1 diabetes (13.33%). Of these, four had firstdegree relatives affected (6.67%) and were presented here. Although high-risk genotypes were more frequent in the group of familial cases, no association was found between DR genotype and family history of type 1 diabetes when statistical significance was tested (p value 0.119).


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