scholarly journals Preventive Effects of Ginger Extract and Nigella sativa Oil on Anxiety and Depression Behavior in Wistar Rats Exposed to Mercuric Chloride

2021 ◽  
Vol 14 (1) ◽  
pp. 01-04
Author(s):  
Sabri Benkermiche ◽  
Samir Djemli ◽  
Meriem Haloui ◽  
Mohamed Lamine Bena-bed ◽  
Abdelkrim Tahraoui
Keyword(s):  
Mercuric Chloride ◽  
Wistar Rats ◽  
Nigella Sativa ◽  
Anxiety And Depression ◽  
Ginger Extract ◽  
Nigella Sativa Oil ◽  
Preventive Effects

scholarly journals Nigella sativa oil ameliorates the effects of early weaning on the cerebellum of wistar rats

IBRO Reports ◽  
2019 ◽  
Vol 7 ◽  
pp. 18
Author(s):  
R. Jaji-Sulaimon ◽  
M.B. Adekunle ◽  
I.T. Gbadamosi ◽  
G.O. Omotoso
Keyword(s):  
Wistar Rats ◽  
Nigella Sativa ◽  
Early Weaning ◽  
Nigella Sativa Oil

scholarly journals The effect of black cumin oil (Nigella sativa) on the reproduction of male Wistar rats

2021 ◽  
Vol 1 (2) ◽  
pp. 45-49
Author(s):  
Syahran Wael ◽  
Didik Wahyudi ◽  
Tayeb Wael ◽  
Zaid Mohamed Jaber
Keyword(s):  
Wistar Rats ◽  
Nigella Sativa ◽  
Cellular Damage ◽  
Control Group ◽  
Control Group Design ◽  
Black Cumin ◽  
Group Design ◽  
Nigella Sativa Oil ◽  
Post Test ◽  
Male Wistar Rats

Nigella sativa oil is antioxidant compound has the effect that serves to prevent cellular damage. The effect of Nigella sativa oil in the motility and total count of spermatozoa wistar rats. Experimental research with the design of post test only control group design. Wistar rats consists of 24 head and divided into 4 groups consist of control and treatment group. The control group was distilled. The first treatment was of Nigella sativa oil everydays as much with dose 150 mg/kgbw, 250 mg/kgbw, and 350 mg/kgbw, for 16 days, . Statistic test for motility and count of sperm wistar rats use the Kruskal-Wallis followed by Mann Whitney test. Avarage value of motility in the control (21.67±9.832) its lower than treatment. In dose 350 mg/kgbw its highest (52.33±13.292) compare in the treatment 250 mg/kgbw (40.67±17.512) and 150 mg/kgbw (30.67±8.165). avarage value of count sperm in the control (130.83±41.877) its lower than treatments. In dose 350 mg/kgbw its highest (199.67±23.480) compare in the treatment 250 mg/kgbw (187.50±74.538) and 150 mg/kgbw (140.83±32.568). Administration of Nigella sativa oil occur to enhancement motility and number of spermatozoa wistar rats.

scholarly journals Effects of Nigella sativa Linn. Oil on Gut Bacteria and Liver Function Status of Albino Wistar Rats

2019 ◽  
pp. 1-7
Author(s):  
F. Oluwafemi ◽  
P. Ojo ◽  
A. L. Kolapo ◽  
S. O. Oluwalana
Keyword(s):  
Body Weight ◽  
Liver Function ◽  
Wistar Rats ◽  
Nigella Sativa ◽  
Phytochemical Analysis ◽  
Microbial Count ◽  
Blood Samples ◽  
E Coli ◽  
Microbial Counts ◽  
Nigella Sativa Oil

Background: Nigella sativa oil (NSO) has been suggested for use in several food and pharmaceutical applications due to its bioactive contents. Objectives: The present study investigated the effects of 14 µl/g body weight dosage of NSO on body weight, gut microflora and liver function status (LFS) of albino wistar rats. Phytochemical analysis of NSO extract was done. Materials and Methods: Sixty male Wistar rats were randomly assigned into two groups: 14 µl/g body weight of NSO was administered to group A while group B was given an equal volume of distilled water. Five rats provided baseline data for weight, the microbial counts and LFS in a 12-weeks experiment. At two weeks interval, five rats were sacrificed from each group and their intestinal contents were used for the microbial count (Viable, Coliform, E. coli, Staphylococci and Lactic acid bacteria (LAB)) assessment and the blood samples for LFS study. Results: Nigella sativa oil showed the presence of alkaloids (0.083 mg/g), flavonoids (0.302 mg/g), saponins (0.325 mg/g), terpenes (0.138 mg/g), steroids (0.152 mg/g), tannins (0.008 mg/g) and terpenoid (0.138 mg/g). In both groups, the weight of rats continued to increase from the onset of the study, but between 10th and 12th week, non-significant (p>0.05) weight reduction was observed from 191.72±3.23 g to 189.30±4.71 g in the treatment group. Baseline Viable, Coliform, E. coli, Staphylococci and LAB counts (x 106 CFU/g) were 160, 146, 55, 23, and 154 respectively. Sequel to intake of NSO for twelve weeks, the microbial counts (x 106 CFU/g) were respectively 49, 38, 27, 11, and 318. Blood samples also showed a significant (p<0.05) reduction in LFS for Aspartate aminotransferase (78.48 to 60.06U/L), Alanine aminotransferase (30.80 to 18.54 U/L), Alkaline phosphatase (97.00 to 79.34U/L), and Bilirubin (0.52 to 0.20 U/L). Conclusion: Beneficial effects of NSO at the investigated dosage of 14 µl/g body weight has been demonstrated as no toxicological effect was observed.

Subchronic dichlorvos-induced Cardiotoxicity in Wistar rats: Mitigative efficacy of Nigella sativa oil

2018 ◽  
Vol 17 (2) ◽  
pp. 60
Author(s):  
Aminu Imam ◽  
MaryamOluwatobi Busari ◽  
MisturatYetunde Adana ◽  
MusaIyiola Ajibola ◽  
Abdulmumin Ibrahim ◽  
...  
Keyword(s):  
Wistar Rats ◽  
Nigella Sativa ◽  
Nigella Sativa Oil

scholarly journals EFEK NIGELLA SATIVA OIL TERHADAP UKURAN DIAMETER ULKUS TRAUMATIKUS PADA MALE WISTAR RATS SECARA IN VIVO

2016 ◽  
Vol 3 (2) ◽  
pp. 94
Author(s):  
Linda Septiana ◽  
Ratnawati Hendari ◽  
Erwid Fatchur Rahman ◽  
Diyah Fatmasari
Keyword(s):  
Wistar Rats ◽  
Nigella Sativa ◽  
Pathological Condition ◽  
Negative Control Group ◽  
Negative Control ◽  
Control Group ◽  
Epithelial Tissue ◽  
Nigella Sativa Oil ◽  
Male Wistar Rats

Background: Ulcer is a pathological condition characterized by loss of epithelial tissue. Ulcer will experience healing within 2 weeks after trauma source is removed. Nigella sativa Oil has been known to heal wounds. The purpose of this study was to evaluate the effect of NSO on healing of ulcers in male wistar rats from the use of chemicals.Method: This study design was quasi-experimental methods. Ten male wistar rats were exposing the H2O2 on the mandibular anterior gingiva. divided into negatif control group and NSO group. NSO group treated twice daily for 10 days. Observaton wound size was measured on 0, 3,7, 10 days. The results were analayzed with Repeated Anova test and LSD test.Result: The observations difference diameter of traumatic ulcer negative control group and NSO on 0-10 days was 1.458 mm and 2.182 mm. The results of data analysis showed that there are significant differences (p<0,05) between negatif control group and NSO.Conclusion: NSO has an influence of the size reduction of the diameter of traumatic ulcers.

Sign in / Sign up

Export Citation Format

Share Document