Phytochemical Investigation and Antiepileptic Activity of Asparagus racemosus (Wild) Root Extracts in Rodents

Background: The root extracts of Asparagus racemosus (shatamuli) has been used as benign as reducing agent to reduce graphene oxide (GO) to reduced form of graphene oxide (rGO). The root extract used as a green reducing agent that is non-toxic, eco-friendly and natural therapeutic. Methods: The formation of rGO was identified using XRD, FTIR, TEM and EDX techniques. Results: The DLS and Zeta potential data revealed that the hydrodynamic size of these rGO is lower than 200 nm with optimal charge. Conclusion: These results may be useful for the use of GO as probe in biomedical research where the plant species has known biomedical applications.

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Phytochemical Investigation and Antimicrobial Activity of Root Extracts of Withania Somnifera (L.) Dunal. against Drug- Resistant Bacterial Pathogens

Indian Journal of Public Health Research & Development ◽

10.37506/v10/i12/2019/ijphrd/192343 ◽

2019 ◽

Vol 10 (12) ◽

pp. 2265

Author(s):

Thirunavukkarasu Umaarasu ◽

Kesavaram Padmavathy ◽

Dharmalingam Thirunavukkarasu ◽

Jayamathi Govindaraj ◽

S. V. Rajesh ◽

...

Keyword(s):

Antimicrobial Activity ◽

Withania Somnifera ◽

Bacterial Pathogens ◽

Drug Resistant ◽

Root Extracts ◽

Phytochemical Investigation

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Chemometric analysis of selective polyphenolic groups in Asparagus racemosus (Shatavar) root extracts by traditional and supercritical fluid (CO2) based extractions

Separation Science and Technology ◽

10.1080/01496395.2019.1594896 ◽

2019 ◽

Vol 55 (7) ◽

pp. 1339-1355 ◽

Cited By ~ 2

Author(s):

Mojeer Hasan ◽

Bibhu Prasad Panda

Keyword(s):

Supercritical Fluid ◽

Chemometric Analysis ◽

Asparagus Racemosus ◽

Root Extracts ◽

Supercritical Fluid Co2

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Madhuca longifolia water extract revealed protective effect against MES, PTZ and Li-pilocarpine induced epilepsy

The Journal of Phytopharmacology ◽

10.31254/phyto.2018.7307 ◽

2018 ◽

Vol 7 (3) ◽

pp. 270-274

Author(s):

Chandrakant V Thakare ◽

◽

Chandrashekhar D Upasani ◽

Keyword(s):

Amino Acid ◽

Treatment Group ◽

Protective Effect ◽

Water Extract ◽

Laboratory Animals ◽

Protein Amino Acid ◽

Antiepileptic Activity ◽

Phytochemical Investigation ◽

End Of Treatment ◽

Madhuca Longifolia

Objective: Present study was designed to screen the antiepileptic property of aqueous extract of Madhucalongifolia (AqML) in laboratory animals. Materials and methods: Rat and mice were divided in different groups. Antiepileptic activity was tested by using maximal electric shock (MES), Pentylenetertrazole (PTZ) and lithium pilocarpine (Li-Pilocarpine) models. Treatment group of animals were received AqML at 100, 200 and 400 mg/kg p.o. for 7 days. At the end of treatment period, different parameters related of antiepileptic action were observed. Result: Preliminary phytochemical investigation revealed the presence of carbohydrate, protein, amino acid and alkaloids. Animals treatment with AqML showed significant (p<0.05) antiepileptic activity in MES, PTZ and li-pilocarpine screening models. In all the screening models AqML showed dose dependant prevention in seizure was observed and of them dose 400mg/kg p.o. was found to be very significant (p<0.05) antiepileptic effect. Conclusion: The result revealed that AqML at 400 mg/kg p.o. possesses antiepileptic activity in MES, PTZ and Li-pilocarpine models

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