A Comparison Of Three-Drug Anti-Tuberculous Treatment And Directly Observed Treatment Short Course In The Treatment Of Tuberculous Lymphadenitis

10.5580/2c06 ◽  
2012 ◽  
Vol 10 (1) ◽  
2021 ◽  
Vol 9 ◽  
pp. 205031212198949
Author(s):  
Cylia Nkechi Iweama ◽  
Olaoluwa Samson Agbaje ◽  
Prince Christian Ifeanachor Umoke ◽  
Chima Charles Igbokwe ◽  
Eyuche Lawretta Ozoemena ◽  
...  

Introduction: Tuberculosis is a public health problem in Nigeria. One of the most effective ways of controlling tuberculosis is the directly observed treatment short-course. However, some factors influence tuberculosis patients’ treatment nonadherence via directly observed treatment short-course. The study objective was to assess medication nonadherence and associated factors among tuberculosis patients in north-west Nigeria. Methods: A cross-sectional study enrolled tuberculosis patients using directly observed treatment short-course in public health facilities in Kano and Kaduna States from January 2015 to June 2016. The sample selection was conducted via a multistage sampling procedure. Data were collected using tuberculosis patients’ demographic and clinical characteristics forms, well-validated structured instruments, and medical records. SPSS version 20 was used for data analysis. Logistic and multivariable logistic regression analyses to determine factors of medication nonadherence ( P < 0.05) Results: Complete responses from 390 patients out of the 460 patients recruited for the study were used for data analyses. The mean age was 51.5 (standard deviation = ±13.8) years. The mean tuberculosis medication adherence questionnaire score was 4.35 ± 1.12. The prevalence of nonadherence to tuberculosis medication was 30.5%. Multivariable logistic regression analysis showed that having a monthly income between #100,000 and #199, 000 (adjusted odds ratio = 0.01; 95% confidence interval: 0.00–0.13), being widowed (adjusted odds ratio = 26.74, 95% confidence interval: 2.92–232.9), being married (adjusted odds ratio = 120.49, 95% confidence interval: 5.38–271.1), having a distance <5 km to directly observed treatment short-course center from home (adjusted odds ratio = 0.06, 95% confidence interval: 0.00–0.01), having a tuberculosis/HIV co-infection (adjusted odds ratio = 0.01, 95% confidence interval: 0.12–0.35), use of antiretroviral treatment and cotrimoxazole prophylaxis therapy medications (adjusted odds ratio = 24.9, 95% confidence interval: 19.6–304.3) were associated with tuberculosis medication nonadherence. Conclusion: Tuberculosis medication nonadherence was high among the patients. Thus, patient-specific adherence education, attenuation of potential factors for tuberculosis medication nonadherence, and continual resource support for tuberculosis patients are needed to improve treatment outcomes.


Author(s):  
A. Divya ◽  
Dhaval P. Shukla ◽  
Veenakumari H. Bahubali ◽  
Rose Dawn Bharath ◽  
B.N. Nandeesh ◽  
...  

Author(s):  
Masoud Behzadifar ◽  
Masoud Mirzaei ◽  
Meysam Behzadifar ◽  
Abouzar Keshavarzi ◽  
Maryam Behzadifar ◽  
...  

2017 ◽  
Vol 10 (1) ◽  
pp. 19
Author(s):  
Diah Hermayanti

Latar belakang : Pengendalian TBC di Indonesia, dilaksanakan dengan strategi Directly Observed Treatment Short Course (DOTS). Prinsip pengobatan TBC strategi DOTS menggunakan obat anti tuberkulosa (OAT) yang diberikan dalam bentuk kombinasi dari beberapa jenis, dalam jumlah cukup, dan dosis tepat selama 6 – 8 bulan. Penderita dikategorikkan sebagai kasus konversi BTA negatif bila dalam pemeriksaan ulangan BTA masih dijumpai kuman BTA positif dalam sputumnya.Tujuan : mengeksplorasi lebih lanjut faktor-faktor yang diduga dapat menyebabkan terjadinya konversi BTA negatif pada akhirmasa intensif pengobatan dan pada penderita dengan kategori gagal. Metode : Penelitian deskriptif observasional dengan pendekatan studi cross sectional, yang dilakukan di Poli Puskesmas Kedung Kandang Malang. Hasil penelitian : didapatkan 4 penderita yang masuk kriteria konversi BTA negatif dengan pendidikan 75% SD dan 25% SMP; status gizi berdasarkan IMT 75% termasuk kriteria kurus; 100% taat berobat; dan pada semua pemeriksaan kultur sputum tidak dijumpai pertumbuhan kuman. Kesimpulan : Status sosial ekonomi dan status gizi penderita TBC dengan konversi BTA negatif adalah rendah, namun kepatuhannya berobat cukup tinggi. Resistensi kuman TBC terhadap OAT program jangka pendek pada penelitian tidak dapat dievaluasi oleh karena tidak ada pertumbuhan kuman pada semua sampel sputum penderita.Kata kunci : DOTS, OAT, BTA, Konversi negative


2013 ◽  
Vol 7 (10) ◽  
pp. 447
Author(s):  
Dewi Rokhmah

Saat ini, fokus utama dari pelayanan kesehatan masih bertumpu pada aspek medis yang sangat kurang memperhatikan isu sosial termasuk gender yang merupakan penyebab utama kesenjangan bidang kesehatan di masyarakat kita. Tuberkulosis adalah penyakit yang menyebabkan kematian di seluruh dunia. Gender berperan sebagai salah satu determinan penyakit tuberkulosis meliputi penemuan kasus, diagnosis, dan proses pengobatan. Penelitian ini bertujuan menganalisis perspektif gender pencapaian Program Tuberkulosis Directly Observed Treatment Short-course (DOTS) meliputi penemuan, diagnosis pasien, dan hasil pengobatan di Rumah Sakit Paru Jember, tahun 2010. Penelitian ini menggunakan metode deskriptif analitik menggunakan data sekunder yang berasal dari Laporan Program Tuberkulosis DOTS Tahun 2010. Populasi adalah penduduk yang menderita tuberkulosis yang mendapat pelayanan dalam program DOTS. Sedangkan, sampel dari penelitian ini adalah pasien yang telah didiagnosis tuberkulosis oleh dokter, mendapatkan pelayanan di Poli Paru Rumah Sakit Paru Jember pada tahun 2010. Data yang terkumpul dianalisis secara diskriptif dengan perspektif gender. Hasil penelitian menunjukkan bahwa dalam proses penemuan pasien tuberkulosis, perempuan lebih tinggi dari laki-laki. Tetapi dalam proses diagnosis pasien tuberkulosis dan hasil pengobatan pasien tuberkulosis, laki-laki jauh lebih tinggi dari perempuan. Kondisi ini disebabkan karena stigma pada perempuan serta akses dan kontrol perempuan yang rendah terhadap pengelolaan sumber daya untuk kesehatan. Komitmen pemerintah dan masyarakat yang sensitif gender diperlukan dalam intervensi program tuberkulosis DOTS pada masa yang akan datang.Nowadays main focus of health care remains in medical aspect and lack on social issue include gender identities which are being main cause of the health gap in our society. Tuberculosis is a disease caused mortality in the worldwide. The role of gender as a determinant of health status, including all aspects of tuberculosis, from case finding, diagnosis, and treatment result of tuberculosis patient. The objective of this research was an analysis of gender perspective the reach of Tuberculosis Directly Observed Treatment Short-course (DOTS) program from case finding, diagnosis, and treatment result of tuberculosis patient in Lung Hospital of Jember in 2010. This research was descriptive analytic method used secondary data from the report of Tuberculosis DOTS program at 2010. The population of this research is people with Tuberculosis have accessed services from DOTS program. The sample of this research are man and woman patient, have been diagnosed as tuberculosis patient by doctor, getting services in Lung Poly in Lung Hospital of Jember in 2010. Collected data are analyzed descriptively with a gender perspective. The result of this research shows that in tuberculosis patient finding process, woman is higher than man, but in the diagnosis and treatment result of tuberculosis patient, man is higher than woman. This condition was caused by woman had stigma and low access and control in managing resources for health. Gender sensitivity commitment by government and society is needed to the intervention both in tuberculosis DOTS program applying in the future.


Author(s):  
Daxaben Patel ◽  
Khushbu Patel

Introduction: Tuberculosis is one of the most prominent mycobacterium diseases known to humankind. Increasing cases world-wide led to the World Health Organization (WHO) declaring a global Emergency in April 1993. Despite the availability of „tools‟ for controlling TB, programs have been unable to sustain high cure rate. As a consequence of this, and the increasing problems of drug resistance, the International community, through the WHO, has developed and launched the Directly Observed Treatment Short Course (DOTS) strategy. Directly Observed Treatment, Short course chemotherapy is a strategy to ensure cure by providing the most effective medicine and confirming that it is taken. It is the only strategy which has been documented to be effective Worldwide on a program basis. Design: A quantitative approach using pre-experimental pre-test post-test design with one group. Participants: 50 Staff Nurses were selected using Non-Probability purposive sampling technique in Mehsana District. Interventions: Structured teaching was given to the Staff Nurses. Tool: Self Structured Questionnaire was used to assess the level of Knowledge regarding tuberculosis and dots therapy among staff nurses. Results: The research study shows that in pre test (20%) of sample had a poor knowledge (score 1-10) regarding knowledge about tuberculosis and dots therapy, while average knowledge (score 11-20) was observed in 46% of the sample and (34%) of sample having good (20-41) knowledge score. And in the post test (0%) of sample had a poor knowledge (score 1-10) regarding knowledge about tuberculosis and dots therapy, while average knowledge (score 11-20) was observed in (18%) of the sample and (82%) of sample having good (20-41) knowledge score. And the comparison between pre test and post test observation score regarding knowledge of tuberculosis and dots therapy. The mean pre test observation score was 16.4 and the mean post test score was the 23, and the Standard Deviation was 5.64 in pre test and 7.67 in post test score, also the calculated “t”value was 4.20 was greater than the table value at 0.05 level of significance. The structured teaching was effective in increasing the Knowledge regarding tuberculosis and dots therapy among staff nurses. Chi-square test to associate the level of knowledge and selected demographic variable. Conclusion: The findings of the study indicate that structured teaching programme is effective in increase knowledge regarding tuberculosis and dots therapy among staff nurses.


2019 ◽  
Vol 5 (1) ◽  
pp. 56
Author(s):  
Ramanathan Thenambigai ◽  
HuluvadiShivalingaiah Anwith ◽  
SreeramaReddy Kaushik ◽  
M Madhusudan ◽  
DandiganahalliShivaram Priyanka ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document