Adverse drug reactions in tuberculosis patients: consequences for TB control

2015 ◽  
Vol 19 (5) ◽  
pp. 621-622
Author(s):  
Balaji R. Naik ◽  
Suresh G. Shastri ◽  
N. S. Vishwanath ◽  
M. D. Suryakanth ◽  
Anil Sigarajipur ◽  
...  
2020 ◽  
pp. 1-3
Author(s):  
Rupam Kumar Ta ◽  
Pronoy Sen

BACKGROUND: The emergence of drug resistant mycobacterium has become a signicant public health problem creating an obstacle to effective Tuberculosis (TB) control. Freedom from TB is possible with timely, regular, complete treatment, with assurance, prevention and management of side effects of antitubercular drugs. Present study was conducted to evaluate common and rare adverse drug reactions (ADR) of CAT IV and CAT V to analyse demographic, radiological and bacteriological prole and treatment outcome in MDR &XDR patients. Aims and Objectives- To evaluate the common and rare adverse drug reactions of intensive phase treatment of Multi Drug Resistant Tuberculosis (MDR) and Extensively Drug Resistant Tuberculosis (XDR) as per WHO-UMC Causality Assessment Scale. METHODS: 76 patients of MDR and XDR Tuberculosis were admitted in DR-TB (Drug Resistant TB) centre, Burdwan Medical College and Hospital and the adverse drug reaction prole of 2nd line drugs were analysed during the intensive phase for a year after fullling the inclusion and exclusion criteria. Treatment was given as per guidelines by Revised National TB Control Program PMDT (Programmatic management of drug-resistant TB). RESULTS:Adverse drug reactions on GI system were nausea 73 patients (96.10%), vomiting 70 (92.10%), acidity 41 (53.9%), and sulphurous belching and hepatitis 1 (1.31%) each. CONCLUSIONS: The reactions were common in rst 60 days of the regimen and in patients with BMI ≤18. Hence vigilant monitoring is required for these types of patients during the initial period and sputum smear and culture conversion is very well correlated with clinical and radiological improvement.


2020 ◽  
Vol 67 (1) ◽  
pp. 20-28
Author(s):  
Lalitha Krishnappa ◽  
Suman Gadicherla ◽  
Priyadarshini Chidambaram ◽  
H.V. Anuradha ◽  
Shivaraj Nallur Somanna ◽  
...  

2018 ◽  
Vol 25 (5) ◽  
pp. e533-e540 ◽  
Author(s):  
Nafees Ahmad ◽  
Arshad Javaid ◽  
Syed Azhar Syed Sulaiman ◽  
Afsar Khan Afridi ◽  
Zainab ◽  
...  

2019 ◽  
Vol 10 (2) ◽  
pp. 198-204
Author(s):  
Ramakrishna Prudhivi ◽  
Siva Reddy Challa ◽  
Basaveswara Rao MV ◽  
Veena G ◽  
Bhaskara N Rao ◽  
...  

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