Newly discovered Staphylococcus aureus serine hydrolase probe and drug targets
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There is an urgent need for new diagnosis and treatment options for the bacterial pathogen Staphylococcus aureus. This review will summarize data on ten recently discovered biofilm-associated serine hydrolases called fluorophosphonate-binding hydrolases (FphA-J). Based on the summarized findings, many of these proteins represent intriguing new targets for probe and drug development. ©2021 by the authors. This article is an open-access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/4.0/).
2019 ◽
Vol 36
(ICON-Suppl)
◽
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2020 ◽
Vol 4
(2)
◽
pp. 149