scholarly journals Explainable Medical Image Segmentation via Generative Adversarial Networks and Layer-wise Relevance Propagation

2021 ◽  
Vol 1 (1) ◽  
pp. 20-22
Author(s):  
Awadelrahman M. A. Ahmed ◽  
Leen A. M. Ali

This paper contributes in automating medical image segmentation by proposing generative adversarial network based models to segment both polyps and instruments in endoscopy images. A main contribution of this paper is providing explanations for the predictions using layer-wise relevance propagation approach, showing which pixels in the input image are more relevant to the predictions. The models achieved 0.46 and 0.70, on Jaccard index and 0.84 and 0.96 accuracy, on the polyp segmentation and the instrument segmentation, respectively.

2020 ◽  
Vol 10 (15) ◽  
pp. 5032
Author(s):  
Xiaochang Wu ◽  
Xiaolin Tian

Medical image segmentation is a classic challenging problem. The segmentation of parts of interest in cardiac medical images is a basic task for cardiac image diagnosis and guided surgery. The effectiveness of cardiac segmentation directly affects subsequent medical applications. Generative adversarial networks have achieved outstanding success in image segmentation compared with classic neural networks by solving the oversegmentation problem. Cardiac X-ray images are prone to weak edges, artifacts, etc. This paper proposes an adaptive generative adversarial network for cardiac segmentation to improve the segmentation rate of X-ray images by generative adversarial networks. The adaptive generative adversarial network consists of three parts: a feature extractor, a discriminator and a selector. In this method, multiple generators are trained in the feature extractor. The discriminator scores the features of different dimensions. The selector selects the appropriate features and adjusts the network for the next iteration. With the help of the discriminator, this method uses multinetwork joint feature extraction to achieve network adaptivity. This method allows features of multiple dimensions to be combined to perform joint training of the network to enhance its generalization ability. The results of cardiac segmentation experiments on X-ray chest radiographs show that this method has higher segmentation accuracy and less overfitting than other methods. In addition, the proposed network is more stable.


2020 ◽  
Author(s):  
Kun Chen ◽  
Manning Wang ◽  
Zhijian Song

Abstract Background: Deep neural networks have been widely used in medical image segmentation and have achieved state-of-the-art performance in many tasks. However, different from the segmentation of natural images or video frames, the manual segmentation of anatomical structures in medical images needs high expertise so the scale of labeled training data is very small, which is a major obstacle for the improvement of deep neural networks performance in medical image segmentation. Methods: In this paper, we proposed a new end-to-end generation-segmentation framework by integrating Generative Adversarial Networks (GAN) and a segmentation network and train them simultaneously. The novelty is that during the training of the GAN, the intermediate synthetic images generated by the generator of the GAN are used to pre-train the segmentation network. As the advances of the training of the GAN, the synthetic images evolve gradually from being very coarse to containing more realistic textures, and these images help train the segmentation network gradually. After the training of GAN, the segmentation network is then fine-tuned by training with the real labeled images. Results: We evaluated the proposed framework on four different datasets, including 2D cardiac dataset and lung dataset, 3D prostate dataset and liver dataset. Compared with original U-net and CE-Net, our framework can achieve better segmentation performance. Our framework also can get better segmentation results than U-net on small datasets. In addition, our framework is more effective than the usual data augmentation methods. Conclusions: The proposed framework can be used as a pre-train method of segmentation network, which helps to get a better segmentation result. Our method can solve the shortcomings of current data augmentation methods to some extent.


Author(s):  
Chaoyue Wang ◽  
Chaohui Wang ◽  
Chang Xu ◽  
Dacheng Tao

In this paper, we propose a principled Tag Disentangled Generative Adversarial Networks (TD-GAN) for re-rendering new images for the object of interest from a single image of it by specifying multiple scene properties (such as viewpoint, illumination, expression, etc.). The whole framework consists of a disentangling network, a generative network, a tag mapping net, and a discriminative network, which are trained jointly based on a given set of images that are completely/partially tagged (i.e., supervised/semi-supervised setting). Given an input image, the disentangling network extracts disentangled and interpretable representations, which are then used to generate images by the generative network. In order to boost the quality of disentangled representations, the tag mapping net is integrated to explore the consistency between the image and its tags. Furthermore, the discriminative network is introduced to implement the adversarial training strategy for generating more realistic images. Experiments on two challenging datasets demonstrate the state-of-the-art performance of the proposed framework in the problem of interest.


2017 ◽  
Author(s):  
Benjamin Sanchez-Lengeling ◽  
Carlos Outeiral ◽  
Gabriel L. Guimaraes ◽  
Alan Aspuru-Guzik

Molecular discovery seeks to generate chemical species tailored to very specific needs. In this paper, we present ORGANIC, a framework based on Objective-Reinforced Generative Adversarial Networks (ORGAN), capable of producing a distribution over molecular space that matches with a certain set of desirable metrics. This methodology combines two successful techniques from the machine learning community: a Generative Adversarial Network (GAN), to create non-repetitive sensible molecular species, and Reinforcement Learning (RL), to bias this generative distribution towards certain attributes. We explore several applications, from optimization of random physicochemical properties to candidates for drug discovery and organic photovoltaic material design.


2021 ◽  
Vol 11 (15) ◽  
pp. 7034
Author(s):  
Hee-Deok Yang

Artificial intelligence technologies and vision systems are used in various devices, such as automotive navigation systems, object-tracking systems, and intelligent closed-circuit televisions. In particular, outdoor vision systems have been applied across numerous fields of analysis. Despite their widespread use, current systems work well under good weather conditions. They cannot account for inclement conditions, such as rain, fog, mist, and snow. Images captured under inclement conditions degrade the performance of vision systems. Vision systems need to detect, recognize, and remove noise because of rain, snow, and mist to boost the performance of the algorithms employed in image processing. Several studies have targeted the removal of noise resulting from inclement conditions. We focused on eliminating the effects of raindrops on images captured with outdoor vision systems in which the camera was exposed to rain. An attentive generative adversarial network (ATTGAN) was used to remove raindrops from the images. This network was composed of two parts: an attentive-recurrent network and a contextual autoencoder. The ATTGAN generated an attention map to detect rain droplets. A de-rained image was generated by increasing the number of attentive-recurrent network layers. We increased the number of visual attentive-recurrent network layers in order to prevent gradient sparsity so that the entire generation was more stable against the network without preventing the network from converging. The experimental results confirmed that the extended ATTGAN could effectively remove various types of raindrops from images.


Author(s):  
Lingyu Yan ◽  
Jiarun Fu ◽  
Chunzhi Wang ◽  
Zhiwei Ye ◽  
Hongwei Chen ◽  
...  

AbstractWith the development of image recognition technology, face, body shape, and other factors have been widely used as identification labels, which provide a lot of convenience for our daily life. However, image recognition has much higher requirements for image conditions than traditional identification methods like a password. Therefore, image enhancement plays an important role in the process of image analysis for images with noise, among which the image of low-light is the top priority of our research. In this paper, a low-light image enhancement method based on the enhanced network module optimized Generative Adversarial Networks(GAN) is proposed. The proposed method first applied the enhancement network to input the image into the generator to generate a similar image in the new space, Then constructed a loss function and minimized it to train the discriminator, which is used to compare the image generated by the generator with the real image. We implemented the proposed method on two image datasets (DPED, LOL), and compared it with both the traditional image enhancement method and the deep learning approach. Experiments showed that our proposed network enhanced images have higher PNSR and SSIM, the overall perception of relatively good quality, demonstrating the effectiveness of the method in the aspect of low illumination image enhancement.


Author(s):  
Johannes Haubold ◽  
René Hosch ◽  
Lale Umutlu ◽  
Axel Wetter ◽  
Patrizia Haubold ◽  
...  

Abstract Objectives To reduce the dose of intravenous iodine-based contrast media (ICM) in CT through virtual contrast-enhanced images using generative adversarial networks. Methods Dual-energy CTs in the arterial phase of 85 patients were randomly split into an 80/20 train/test collective. Four different generative adversarial networks (GANs) based on image pairs, which comprised one image with virtually reduced ICM and the original full ICM CT slice, were trained, testing two input formats (2D and 2.5D) and two reduced ICM dose levels (−50% and −80%). The amount of intravenous ICM was reduced by creating virtual non-contrast series using dual-energy and adding the corresponding percentage of the iodine map. The evaluation was based on different scores (L1 loss, SSIM, PSNR, FID), which evaluate the image quality and similarity. Additionally, a visual Turing test (VTT) with three radiologists was used to assess the similarity and pathological consistency. Results The −80% models reach an SSIM of > 98%, PSNR of > 48, L1 of between 7.5 and 8, and an FID of between 1.6 and 1.7. In comparison, the −50% models reach a SSIM of > 99%, PSNR of > 51, L1 of between 6.0 and 6.1, and an FID between 0.8 and 0.95. For the crucial question of pathological consistency, only the 50% ICM reduction networks achieved 100% consistency, which is required for clinical use. Conclusions The required amount of ICM for CT can be reduced by 50% while maintaining image quality and diagnostic accuracy using GANs. Further phantom studies and animal experiments are required to confirm these initial results. Key Points • The amount of contrast media required for CT can be reduced by 50% using generative adversarial networks. • Not only the image quality but especially the pathological consistency must be evaluated to assess safety. • A too pronounced contrast media reduction could influence the pathological consistency in our collective at 80%.


Author(s):  
Huilin Zhou ◽  
Huimin Zheng ◽  
Qiegen Liu ◽  
Jian Liu ◽  
Yuhao Wang

Abstract Electromagnetic inverse-scattering problems (ISPs) are concerned with determining the properties of an unknown object using measured scattered fields. ISPs are often highly nonlinear, causing the problem to be very difficult to address. In addition, the reconstruction images of different optimization methods are distorted which leads to inaccurate reconstruction results. To alleviate these issues, we propose a new linear model solution of generative adversarial network-based (LM-GAN) inspired by generative adversarial networks (GAN). Two sub-networks are trained alternately in the adversarial framework. A linear deep iterative network as a generative network captures the spatial distribution of the data, and a discriminative network estimates the probability of a sample from the training data. Numerical results validate that LM-GAN has admirable fidelity and accuracy when reconstructing complex scatterers.


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