Methodological Aspects of Plant Sterol and Stanol Measurement

2015 ◽  
Vol 98 (3) ◽  
pp. 674-676 ◽  
Author(s):  
Dieter Lütjohann

Abstract Cholesterol, its biosynthetic precursors, its metabolite 5α-cholestanol and plant sterols are widely used today in clinical lipid research as surrogate markers of cholesterol synthesis and absorption. Advances in analytical methods for the determination of serum noncholesterol sterols and stanols within the last century are highlighted. This review focuses on sample preparation, separation, and detection techniques. Various aspects related to sterol and stanol analysis from biological samples are discussed.

Author(s):  
Lobna M. Abdel-Aziz ◽  
Ahmed A. Soror ◽  
Ahmed A. Hassan ◽  
Ahmed S. Ali ◽  
Ahmed A. Hafez ◽  
...  

Chlordiazepoxide is considered one of most important sedative and hypnotic benzodiazepines drugs which is currently used all over the world with the increased rate of anxiety drugs. In this literature review, we will introduce the pharmacological action of this drug in addition to most of up-to-date reported methods that have been developed for determination of chlordiazepoxide in its pure form, combined form with other drugs, combined form with degradation products, and in biological samples. Most of the reported analytical methods will focus on spectroscopic, chromatographic and electrochemical techniques.


2020 ◽  
Vol 1 (1) ◽  
pp. 01-11
Author(s):  
Mahmoud Sebaiy

In this review article, we will introduce all reported methods that have been developed for determination of certain anti-tussive and anti-histaminic drugs such as salbutamol, ambroxol and fexofenadine in their pure form, combined form with other drugs, combined form with degradation products, and in biological samples. We also will shed the light on the most important combination of drugs that are used for treatment of asthma and related diseases.


2012 ◽  
Vol 35 (18) ◽  
pp. 2373-2389 ◽  
Author(s):  
Yanawath Santaladchaiyakit ◽  
Supalax Srijaranai ◽  
Rodjana Burakham

Bioanalysis ◽  
2011 ◽  
Vol 3 (1) ◽  
pp. 97-118 ◽  
Author(s):  
Mohammad N Uddin ◽  
Victoria F Samanidou ◽  
Ioannis N Papadoyannis

2013 ◽  
Vol 2013 ◽  
pp. 1-23 ◽  
Author(s):  
Zoraida Sosa-Ferrera ◽  
Cristina Mahugo-Santana ◽  
José Juan Santana-Rodríguez

Endocrine-disruptor compounds (EDCs) can mimic natural hormones and produce adverse effects in the endocrine functions by interacting with estrogen receptors. EDCs include both natural and synthetic chemicals, such as hormones, personal care products, surfactants, and flame retardants, among others. EDCs are characterised by their ubiquitous presence at trace-level concentrations and their wide diversity. Since the discovery of the adverse effects of these pollutants on wildlife and human health, analytical methods have been developed for their qualitative and quantitative determination. In particular, mass-based analytical methods show excellent sensitivity and precision for their quantification. This paper reviews recently published analytical methodologies for the sample preparation and for the determination of these compounds in different environmental and biological matrices by liquid chromatography coupled with mass spectrometry. The various sample preparation techniques are compared and discussed. In addition, recent developments and advances in this field are presented.


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