scholarly journals The Role of Sex Steroids in the Host-Parasite Interaction

Sex Steroids ◽  
10.5772/25580 ◽  
2012 ◽  
Author(s):  
Karen Nava-Castro ◽  
Romel Hernndez-Bello ◽  
Sa Muiz-Hernndez ◽  
Jorge Morales-Montor
Keyword(s):  
Sex Steroids ◽  
Host Parasite

scholarly journals P080 The role of exogenous sex steroids on the vaginal microbiota: a systematic review

2021 ◽  
Author(s):  
L Ratten ◽  
E Plummer ◽  
C Bradshaw ◽  
C Fairley ◽  
S Garland ◽  
...  
Keyword(s):  
Systematic Review ◽  
Sex Steroids ◽  
Vaginal Microbiota

scholarly journals Role of Sex Steroids in β Cell Function, Growth, and Survival

2016 ◽  
Vol 27 (12) ◽  
pp. 844-855 ◽  
Author(s):  
Franck Mauvais-Jarvis
Keyword(s):  
Sex Steroids ◽  
Cell Function ◽  
Β Cell ◽  
Growth And Survival ◽  
Β Cell Function

The possible role of the frontal and sub-parietal gland systems of the pentastomidReighardia sternae(Diesing, 1864) in the evasion of the host immune response

Parasitology ◽  
1979 ◽  
Vol 78 (1) ◽  
pp. 53-66 ◽  
Author(s):  
J. Riley ◽  
J. L. James ◽  
A. A. Banaja
Keyword(s):  
Immune Response ◽  
Alternative Explanation ◽  
Surface Membrane ◽  
Membrane System ◽  
Host Immune Response ◽  
Entire Surface ◽  
Strong Immune Response ◽  
Concomitant Immunity ◽  
Host Parasite

SUMMARYThe frontal and sub-parietal glands of the pentastomidReighardia sternaeelaborate lamellate secretion which is poured on to the cuticle. The entire surface of the cuticle, including the mouth, hook pits and reproductive apertures, is coated with secretion. Electron microscope studies indicate that the glands are continuously active, which implies a turnover of surface membranes. The postulated function of these membranes is to protect certain vital areas of the host–parasite interface, notably the pores of ion-transporting cells, from the host immune response. The available evidence suggests that pentastomids do evoke a strong immune response but since most are long-lived they must circumvent it. We believe the surface membrane system to be instrumental in this. Studies on another pentastomid,Porocephalus crotaliin rats have shown that an immune response stimulated by a primary infection will kill subsequent infections and that the surface membranes are strongly immunogenic. Obvious parallels between this situation and that of schistosome infections in mammals are discussed. An alternative explanation of concomitant immunity is proposed.

The potential role of stress and sex steroids in heritable effects of sevoflurane

2021 ◽  
Author(s):  
Anatoly E Martynyuk ◽  
Ling-Sha Ju ◽  
Timothy E Morey
Keyword(s):  
Sex Steroids ◽  
Age Groups ◽  
Postnatal Period ◽  
Health Concern ◽  
General Anesthetics ◽  
Pharmacological Agents ◽  
Experimental Findings ◽  
Heritable Effects

Abstract Most surgical procedures require general anesthesia, which is a reversible deep sedation state lacking all perception. The induction of this state is possible because of complex molecular and neuronal network actions of general anesthetics (GAs) and other pharmacological agents. Laboratory and clinical studies indicate that the effects of GAs may not be completely reversible upon anesthesia withdrawal. The long-term neurocognitive effects of GAs, especially when administered at the extremes of ages, are an increasingly recognized health concern and the subject of extensive laboratory and clinical research. Initial studies in rodents suggest that the adverse effects of GAs, whose actions involve enhancement of GABA type A receptor activity (GABAergic GAs), can also extend to future unexposed offspring. Importantly, experimental findings show that GABAergic GAs may induce heritable effects when administered from the early postnatal period to at least young adulthood, covering nearly all age groups that may have children after exposure to anesthesia. More studies are needed to understand when and how the clinical use of GAs in a large and growing population of patients can result in lower resilience to diseases in the even larger population of their unexposed offspring. This minireview is focused on the authors’ published results and data in the literature supporting the notion that GABAergic GAs, in particular sevoflurane, may upregulate systemic levels of stress and sex steroids and alter expressions of genes that are essential for the functioning of these steroid systems. The authors hypothesize that stress and sex steroids are involved in the mediation of sex-specific heritable effects of sevoflurane.

scholarly journals B Chromosomes in Populations of Mammals Revisited

Genes ◽  
2018 ◽  
Vol 9 (10) ◽  
pp. 487 ◽  
Author(s):  
Mladen Vujošević ◽  
Marija Rajičić ◽  
Jelena Blagojević
Keyword(s):  
Mammalian Species ◽  
B Chromosome ◽  
Molecular Techniques ◽  
B Chromosomes ◽  
General View ◽  
Protein Coding ◽  
Host Parasite Interactions ◽  
Quantitative Characteristics ◽  
Host Parasite

The study of B chromosomes (Bs) started more than a century ago, while their presence in mammals dates since 1965. As the past two decades have seen huge progress in application of molecular techniques, we decided to throw a glance on new data on Bs in mammals and to review them. We listed 85 mammals with Bs that make 1.94% of karyotypically studied species. Contrary to general view, a typical B chromosome in mammals appears both as sub- or metacentric that is the same size as small chromosomes of standard complement. Both karyotypically stable and unstable species possess Bs. The presence of Bs in certain species influences the cell division, the degree of recombination, the development, a number of quantitative characteristics, the host-parasite interactions and their behaviour. There is at least some data on molecular structure of Bs recorded in nearly a quarter of species. Nevertheless, a more detailed molecular composition of Bs presently known for six mammalian species, confirms the presence of protein coding genes, and the transcriptional activity for some of them. Therefore, the idea that Bs are inert is outdated, but the role of Bs is yet to be determined. The maintenance of Bs is obviously not the same for all species, so the current models must be adapted while bearing in mind that Bs are not inactive as it was once thought.

11 Structure, regulation and role of 3β-hydroxysteroid dehydrogenase, 17β-hydroxysteroid dehydrogenase and aromatase enzymes in the formation of sex steroids in classical and peripheral intracrine tissues

1994 ◽  
Vol 8 (2) ◽  
pp. 451-474 ◽  
Author(s):  
Fernand Labrie ◽  
Jacques Simard ◽  
Van Luu-The ◽  
Georges Pelletier ◽  
Khalid Belghmi ◽  
...  
Keyword(s):  
Sex Steroids ◽  
Hydroxysteroid Dehydrogenase ◽  
Structure Regulation

Wide Distribution of the Serum Levels of DHEA and Sex Steroids in Postmenopausal Women – Relative Role of the Ovary?.

2010 ◽  
pp. P2-429-P2-429
Author(s):  
Fernand Labrie ◽  
Celine Martel ◽  
John Balser
Keyword(s):  
Postmenopausal Women ◽  
Sex Steroids ◽  
Serum Levels ◽  
Wide Distribution ◽  
Relative Role

scholarly journals The role of parasite dispersal in shaping a host–parasite system at multiple evolutionary scales

2018 ◽  
Vol 27 (24) ◽  
pp. 5104-5119 ◽  
Author(s):  
Andrew D. Sweet ◽  
Kevin P. Johnson
Keyword(s):  
Host Parasite

scholarly journals The role of inflammation and potential use of sex steroids in intracranial aneurysms and subarachnoid hemorrhage

2018 ◽  
Vol 9 (1) ◽  
pp. 150 ◽  
Author(s):  
Gustavo Pradilla ◽  
JackW Barrow ◽  
Nefize Turan ◽  
Pasang Wangmo ◽  
AnilK Roy
Keyword(s):  
Subarachnoid Hemorrhage ◽  
Sex Steroids ◽  
Intracranial Aneurysms ◽  
Potential Use
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