scholarly journals Myths Surrounding Covid-19 Vaccine Candidates: A Guide to Fight Back

2021 ◽  
Author(s):  
John Zizzo
Keyword(s):  
Public Health ◽  
Herd Immunity ◽  
Vaccine Uptake ◽  
Protective Measure ◽  
Vaccine Hesitancy ◽  
Health Providers ◽  
Vaccine Candidates ◽  
The Public ◽  
News Organizations ◽  
Public Health Officials

The Covid-19 pandemic has propelled public health officials into the socio-political sphere due to the need for constantly updated information on behalf of the public. However, many individuals choose to acquire health information/guidance from indirect sources, including social media, news organizations, and general word of mouth. As a result, myths and false narratives about various essential health topics, including vaccine characteristics and protective measures, can circulate un-verified between millions of individuals with little recourse. These can further widen the “gap” between public knowledge and current research, resulting in lower vaccine uptake (vaccine hesitancy) and protective measure adherence. Such actions have profound implications as nations attempt to achieve herd immunity and end the pandemic once and for all. Thus, it is vital that public health officials, health providers, researchers, and the general public be able to differentiate common Covid-19 myths from facts and be prepared to approach such interactions via sound reasoning and research-based evidence. This chapter will serve as a guide to accomplish just that.

scholarly journals Determinants of COVID-19 vaccine hesitancy and vaccine uptake in a national cohort of U.S. adults

2021 ◽  
Author(s):  
Madhura S Rane ◽  
Shivani Kochhar ◽  
Emily Poehlein ◽  
William You ◽  
McKaylee Robertson ◽  
...  
Keyword(s):  
Public Health ◽  
Healthcare Workers ◽  
Vaccine Uptake ◽  
Vaccine Hesitancy ◽  
Lower Odds ◽  
The Public ◽  
National Longitudinal Study ◽  
Public Health Threat ◽  
National Cohort ◽  
The U.S

Background Vaccine hesitancy in the U.S. may limit the potential to alleviate the public health threat caused by the COVID-19 pandemic. Methods We estimated trends in and correlates of vaccine hesitancy, and its association with subsequent vaccine uptake among 5,085 United States adults from the CHASING COVID Cohort study, a national longitudinal study. Trends in willingness to vaccinate were examined longitudinally in three rounds of interviews from September to December 2020. We assessed correlates of willingness to vaccinate in December 2020. We also estimated the association between willingness to vaccinate in December 2020 and subsequent vaccine uptake in February 2021. Results Vaccine hesitancy and resistance decreased from 51% and 8% in September 2020 to 35% and 5% in December 2020, respectively. Compared to Non-Hispanic (NH) White participants, NH Black and Hispanic participants had higher adjusted odds ratios (aOR) for both vaccine hesitancy (aOR: 3.3 [95% CI: 2.6, 4.2] for NH Black and 1.8 [95% CI: 1.5, 2.2] for Hispanic) and vaccine resistance (aOR: 6.4 [95% CI: 4.3, 9.4] for NH Black and 1.9 [95% CI: 1.3, 2.7] for Hispanic). Willingness to vaccinate was associated with lower odds of vaccine uptake among 65+ year olds (aOR: 0.4, 95% CI: 0.3, 0.6 for hesitancy; aOR: 0.1, 95% CI: 0.01, 0.6 for resistance) and healthcare workers (aOR: 0.2, 95% CI: 0.1, 0.3 for hesitancy; aOR: 0.04, 95% CI: 0.006, 0.2 for resistance). Conclusions Awareness and distribution efforts should focus on vaccine hesitant vulnerable populations.

scholarly journals Are We Ready for the Arrival of the New COVID-19 Vaccinations? Great Promises and Unknown Challenges Still to Come

Vaccines ◽  
2021 ◽  
Vol 9 (2) ◽  
pp. 173
Author(s):  
Davide Gori ◽  
Chiara Reno ◽  
Daniel Remondini ◽  
Francesco Durazzi ◽  
Maria Pia Fantini
Keyword(s):  
Herd Immunity ◽  
The Elderly ◽  
Vaccine Hesitancy ◽  
Current Crisis ◽  
Complex Issue ◽  
The Public ◽  
The Social ◽  
To Come ◽  
Vaccination Campaigns ◽  
The Eu

While the SARS-CoV-2 pandemic continues to strike and collect its death toll throughout the globe, as of 31 January 2021, the vaccine candidates worldwide were 292, of which 70 were in clinical testing. Several vaccines have been approved worldwide, and in particular, three have been so far authorized for use in the EU. Vaccination can be, in fact, an efficient way to mitigate the devastating effect of the pandemic and offer protection to some vulnerable strata of the population (i.e., the elderly) and reduce the social and economic burden of the current crisis. Regardless, a question is still open: after vaccination availability for the public, will vaccination campaigns be effective in reaching all the strata and a sufficient number of people in order to guarantee herd immunity? In other words: after we have it, will we be able to use it? Following the trends in vaccine hesitancy in recent years, there is a growing distrust of COVID-19 vaccinations. In addition, the online context and competition between pro- and anti-vaxxers show a trend in which anti-vaccination movements tend to capture the attention of those who are hesitant. Describing this context and analyzing its possible causes, what interventions or strategies could be effective to reduce COVID-19 vaccine hesitancy? Will social media trend analysis be helpful in trying to solve this complex issue? Are there perspectives for an efficient implementation of COVID-19 vaccination coverage as well as for all the other vaccinations?

scholarly journals Effectiveness of Face Coverings in Mitigating the COVID-19 Pandemic in the United States

2021 ◽  
Vol 18 (7) ◽  
pp. 3666
Author(s):  
Olukayode James Ayodeji ◽  
Seshadri Ramkumar
Keyword(s):  
Public Health ◽  
United States ◽  
District Of Columbia ◽  
Preventive Measure ◽  
The United States ◽  
Protective Measure ◽  
Sharp Change ◽  
The Public ◽  
Public Health Challenges ◽  
Effective Preventive Measure

The COVID-19 pandemic has been one of the biggest public health challenges of the 21st century. Many prevalent measures have been taken to prevent its spread and protect the public. However, the use of face coverings as an effective preventive measure remains contentious. The goal of the current study is to evaluate the effectiveness of face coverings as a protective measure. We examined the effectiveness of face coverings between 1 April and 31 December 2020. This was accomplished by analyzing trends of daily new COVID-19 cases, cumulative confirmed cases, and cases per 100,000 people in different U.S. states, including the District of Columbia. The results indicated a sharp change in trends after face covering mandates. For the 32 states with face covering mandates, 63% and 66% exhibited a downward trend in confirmed cases within 21 and 28 days of implementation, respectively. We estimated that face covering mandates in the 32 states prevented approximately 78,571 and 109,703 cases within 21- and 28-day periods post face covering mandate, respectively. A statistically significant (p = 0.001) negative correlation (−0.54) was observed between the rate of cases and days since the adoption of a face covering mandate. We concluded that the use of face coverings can provide necessary protection if they are properly used.

scholarly journals A Decision-Making Model for Deterring Food Vendors from Selling Harmless Low-Quality Foods as High-Quality Foods to Consumers

2017 ◽  
Vol 2017 ◽  
pp. 1-8 ◽  
Author(s):  
Po-Yu Chen
Keyword(s):  
Public Health ◽  
Human Health ◽  
Safety Management ◽  
Criminal Liability ◽  
Protective Measure ◽  
Dynamic Approach ◽  
Food Adulteration ◽  
The Public ◽  
Food Market ◽  
Decision Making Model

For certain types of foods, food vendors often label low-quality foods that are harmless to human health as foods of excellent quality and sell these falsely labeled products to consumers. Because this type of food poses no harm to human health, when public health units discover their act of false labeling or food adulteration, vendors are only penalized with a fine rather than having them assume criminal liability. Upon discovering vendors act of falsely labeling food, public health units typically punish the involved parties according to the extent of false labeling. Such static protective measure is ineffective. Instead, the extent of punishment should be based not only on the extent of false labeling, but also on the frequency of food sampling as well as the number of samples obtained for food inspections. Only through this dynamic approach can food adulteration or false labeling be effectively prevented. Adopting the standpoint of the public sector in food safety management, this study developed a mathematical model that facilitates discussion on the aforementioned problems. Furthermore, we discussed how the supply-demand environmental factors of the food market are influenced by the administrative means that the public health units have used to prevent food false labeling.

Understanding vaccine hesitancy: the evidence

2021 ◽  
Vol 32 (7) ◽  
pp. 282-287
Author(s):  
Alison While
Keyword(s):  
Public Health ◽  
Health Professionals ◽  
Herd Immunity ◽  
Public Health Intervention ◽  
Health Intervention ◽  
Vaccine Hesitancy ◽  
Important Public Health ◽  
Positive Attitudes ◽  
The Uk

Vaccine hesitancy is a concern both globally and within the UK. Alison While reviews the evidence relating to vaccine hesitancy, its underlying factors and the sociodemographic variations Vaccination is an important public health intervention, but its effectiveness depends upon the uptake of vaccination reaching sufficient levels to yield ‘herd’ immunity. While the majority of the UK hold positive attitudes about vaccination, some people, including health professionals, decline vaccinations. This article reviews the evidence relating to vaccine hesitancy, its underlying factors and the sociodemographic variations.

scholarly journals Assessment of immunogenicity and protective efficacy of ZyCoV-D DNA vaccine candidates in Rhesus macaques against SARS-CoV-2 infection

2021 ◽  
Author(s):  
Pragya D Yadav ◽  
Sanjay Kumar ◽  
Kshitij Agarwal ◽  
Mukul Jain ◽  
Dilip R Patil ◽  
...  
Keyword(s):  
Vaccine Candidate ◽  
Protective Efficacy ◽  
Rhesus Macaques ◽  
Herd Immunity ◽  
Lavage Fluid ◽  
Injection System ◽  
Protective Measure ◽  
Vaccine Candidates ◽  
Virus Challenge ◽  
Syringe Needle

AbstractVaccines remain the key protective measure to achieve herd immunity to control the disease burden and stop COVID-19 pandemic. We have developed and assessed the immunogenicity and protective efficacy of two formulations (1mg and 2mg) of ZyCoV-D (a plasmid DNA based vaccine candidates) administered through Needle Free Injection System (NFIS) and syringe-needle (intradermal) in rhesus macaques with three dose vaccine regimens. The vaccine candidate 2mg dose administered using Needle Free Injection System (NFIS) elicited a significant immune response with development of SARS-CoV-2 S1 spike region specific IgG and neutralizing antibody (NAb) titers during the immunization phase and significant enhancement in the levels after the virus challenge. In 2 mg NFIS group the IgG and NAb titers were maintained and showed gradual rise during the immunization period (15 weeks) and till 2 weeks after the virus challenge. It also conferred better protection to macaques evident by the viral clearance from nasal swab, throat swab and bronchoalveolar lavage fluid specimens in comparison with macaques from other immunized groups. In contrast, the animals from placebo group developed high levels of viremia and lung disease following the virus challenge. Besides this, the vaccine candidate also induced increase lymphocyte proliferation and cytokines response (IL-6, IL-5).The administration of the vaccine candidate with NFIS generated a better immunogenicity response in comparison to syringe-needle (intradermal route). The study demonstrated immunogenicity and protective efficacy of the vaccine candidate, ZyCoV-D in rhesus macaques.

scholarly journals What Determines Vaccine Hesitancy: Recommendations from Childhood Vaccine Hesitancy to Address COVID-19 Vaccine Hesitancy

Vaccines ◽  
2022 ◽  
Vol 10 (1) ◽  
pp. 80
Author(s):  
Farren Rodrigues ◽  
Suzanne Block ◽  
Suruchi Sood
Keyword(s):  
Literature Review ◽  
Conceptual Model ◽  
Vaccine Uptake ◽  
Childhood Vaccination ◽  
Vaccine Hesitancy ◽  
Extensive Literature ◽  
Health Providers ◽  
Multifaceted Approach ◽  
What Works ◽  
Childhood Vaccine

Vaccine hesitancy is a prevalent and ongoing issue. However, due to the COVID-19 pandemic, additional attention has been brought to the topic of vaccine hesitancy. Vaccine hesitancy is a threat to the population’s health globally. This article aims to acquire insights from previous literature to determine what works to increase vaccine uptake and how we can apply this knowledge to increase COVID-19 vaccine uptake. Research has focused chiefly on childhood vaccination and the hesitancy of caregivers. After conducting an extensive literature review, we have created a conceptual model of indicators that influence vaccine uptake for health providers and caregivers, which can also be used for vaccine recipients. Overall, the reasons for vaccine hesitancy are complex; therefore, a multifaceted approach is needed to address it. Understanding the factors that affect vaccine hesitancy will aid in addressing hesitancy and, in turn, lead to an increase in vaccine uptake.

Current COVID-19 vaccine epidemiology and dentistry

Dental Update ◽  
2021 ◽  
Vol 48 (10) ◽  
pp. 881-886
Author(s):  
Lakshman Samaranayake
Keyword(s):  
Herd Immunity ◽  
Vaccine Recipient ◽  
Vaccine Hesitancy ◽  
Endogenous Factors ◽  
Societal Factors ◽  
The Public ◽  
New Information ◽  
Current Vaccine ◽  
Strain Type

The coronavirus disease 2019 (COVID-19) vaccine story is continuously unfolding. Since our previous COVID-19 commentaries, much new information has transpired on the subject, and here we revisit this topic, which has practical implications for all stakeholders in dentistry, as well as the public. This article, on current vaccine epidemiology, provides an account of why vaccines fail in general, and the particular concerns in relation to the new Delta variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and related ‘variants of concern’. Issues related to vaccine failure are fundamentally dichotomous in nature, appertaining either to the vaccine strain (type) per se, and/or the numerous endogenous factors of the vaccine recipient/vaccinee. Societal factors such as vaccine hesitancy and its impact on herd immunity appear to overarch the long-term goal of total or partial global suppression of SARS-CoV-2, and its eventual endemicity. CPD/Clinical Relevance: To describe the reasons for the failure of currently administered COVID-19 vaccines, particularly in relation to the advent of the SARS-CoV-2 ‘variants of concern’, and discuss implications for clinical dental practice.

scholarly journals Municipal public health officials and the Public Health Act

2016 ◽  
Vol 1 ◽  
Author(s):  
Heidi Lyshol
Keyword(s):  
Public Health ◽  
Health Workers ◽  
Relevant Literature ◽  
Vocational Teachers ◽  
The Public ◽  
New Public Health ◽  
New Public ◽  
Public Health Officials ◽  
Public Health Workers ◽  
Public Health Act

Introduction: The Norwegian Public Health Act of 2012 was intended to give the municipalities a bigger stake in the health of the population by emphasizing public health at a municipal level. The aim of this study was to investigate the effects of the Act on public health officials in the execution of their vocational roles.Research questions: How do public health officials in Norwegian municipalities balance the requirements of the new Public Health Act and what their local leaders, both politicians and bureaucrats, want? How do they use the Act in the performance of their vocational roles? Does this have any relevance for vocational teachers? Method :After a literature search, semi-formal interviews were conducted with 13 municipal public health officials who were also given practical tasks and short questionnaires. The interview transcripts were analysed using Thematic Analysis. This qualitative research technique is defined and described. Discussion and Results: The study shows that the public health workers see the Act as a useful tool and actively use it to leverage the public health field into greater importance. They feel that the Act is empowering, gives them greater pride in their work, and that it helps both them and their superiors to achieve greater understanding of public health workers’ roles in their municipalities. Using the informants’ own words, changes in the municipal public health workers’ roles and vocational self-definitions are discussed in the context of the new Act and selections from the relevant literature. Conclusion: The Public Health Act has changed the roles of municipal public health workers and helped them to further public health by giving them more responsibility and expanded their duty to safeguard health in all policies. The Act is seen as empowering, giving public health professionals pride in their work and greater role understanding, and should be heavily featured in the curriculum of future public health workers.

Public Engagement and Policy Entrepreneurship on Social Media in the Time of Anti-Vaccination Movements

2020 ◽  
pp. 60-80
Author(s):  
Melodie Yunju Song
Keyword(s):  
Public Health ◽  
Public Space ◽  
Public Engagement ◽  
Public Discourse ◽  
Vaccine Hesitancy ◽  
Public Health Issue ◽  
Competing Values ◽  
Mmr Vaccine ◽  
The Public ◽  
Coverage Rates

North America has experienced a resurgence of measles outbreak due to unprecedentedly low Mumps-Measles and Rubella vaccination coverage rates facilitated by the anti-vaccination movement. The objective of this chapter is to explore the new online public space and public discourse using Web 2.0 in the public health arena to answer the question, ‘What is driving public acceptance of or hesitancy towards the MMR vaccine?' More specifically, typologies of online public engagement will be examined using MMR vaccine hesitancy as a case study to illustrate the different approaches used by pro- and anti-vaccine groups to inform, consult with, and engage the public on a public health issue that has been the subject of long-standing public debate and confusion. This chapter provides an overview of the cyclical discourse of anti-vaccination movements. The authors hypothesize that anti-vaccination, vaccine hesitant, and pro-vaccination representations on the online public sphere are reflective of competing values (e.g., modernism, post-modernism) in contemporary society.

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