Intra Articular Ozone Reduces Serum Uric Acid and Improves Pain, Function and Quality of Life in Knee Osteoarthritis Patients: A Before-and-After Study

Various questionnaires are used in patients who undergo rhinologic surgeries but a unique comprehensive questionnaire is needed to evaluate quality of life (QOL) in rhinologic surgeries. The purpose of this study was to prepare a comprehensive questionnaire and compare QOL among four common rhinologic surgeries including functional endoscopic sinus surgery, septoplasty, septorhinoplasty, and septoplasty with turbinoplasty preoperatively and 6 months postoperatively. This was a prospective interventional before-and-after study. Preoperative and 6 months postoperative evaluations were performed with a Modified Health-Related Quality of Life (HRQL) questionnaire designed to cover all needed QOL aspects and the 22-item Sino-nasal Outcome Test questionnaire to cover all needed QOL aspects. The Modified HRQL included 33 items in six subgroups (nasal symptoms, sleep problems, headache, nonnasal symptoms, and practical and emotional problems) and general feeling. From 202 patients who completed the questionnaire before the procedures, 146 (72% of all patients) who were interviewed 6 months postoperatively were included in this study. Comparing preoperative data between followed up patients and missed patients showed no statistical difference among surgeries (p = 0.90). Comparison of patient's pre- and postoperative QOL showed a significant improvement in global QOL and in all questionnaire items (p < 0.0001 in all comparisons). Comparison of QOL changes before and after surgery among different surgeries revealed no statistical difference (p = 0.282). Our data showed a significant improvement in each surgery but the amount of improvement in different surgeries was almost constant.

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Geriatric day hospital improves quality of life: A before and after study

European Geriatric Medicine ◽

10.1016/j.eurger.2013.06.004 ◽

2013 ◽

Vol 4 (5) ◽

pp. 304-309 ◽

Cited By ~ 1

Author(s):

E. de Jaime ◽

O. Vázquez ◽

M.L. Rodríguez ◽

E. Sevilla ◽

S. Burcet ◽

...

Keyword(s):

Quality Of Life ◽

Day Hospital ◽

Before And After ◽

Before And After Study

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The correlation between renal functional reserve and serum uric acid and quality of life in chronic kidney disease stage I–III

KIDNEYS ◽

10.22141/2307-1257.6.2.2017.102788 ◽

2017 ◽

Vol 6 (2) ◽

pp. 99-104

Author(s):

L.M. Savytska

Keyword(s):

Quality Of Life ◽

Chronic Kidney Disease ◽

Uric Acid ◽

Kidney Disease ◽

Serum Uric Acid ◽

Chronic Kidney Disease Stage ◽

Disease Stage ◽

Functional Reserve ◽

Renal Functional Reserve

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Impact of Hearing Aids on Poverty, Quality of Life and Mental Health in Guatemala: Results of a before and after Study

International Journal of Environmental Research and Public Health ◽

10.3390/ijerph17103470 ◽

2020 ◽

Vol 17 (10) ◽

pp. 3470 ◽

Cited By ~ 1

Author(s):

Mark Spreckley ◽

David Macleod ◽

Brenda González Trampe ◽

Andrew Smith ◽

Hannah Kuper

Keyword(s):

Quality Of Life ◽

Mental Health ◽

Hearing Loss ◽

Hearing Aids ◽

Household Income ◽

Comparison Group ◽

Before And After ◽

Before And After Study

There are 466 million people globally with disabling hearing loss, many of whom can benefit from hearing aids. The aim of the study was to assess the impact of providing hearing aids on poverty, mental health, quality of life, and activities, among adults in Guatemala. A nonrandomised before and after study was conducted, with a comparison group to assess for secular trends. Adult cases with bilateral hearing impairment were identified within 150 km of Guatemala City, as well as age- and sex-matched comparison subjects without disabling hearing loss. All participants were interviewed with a semistructured questionnaire, and cases were offered hearing aids. Participants were reinterviewed 6–9 months later. We interviewed 135 cases and 89 comparison subjects at baseline and follow-up. At baseline, cases were poorer than comparison subjects with respect to individual income (p = 0.01), household income (p = 0.02), and per capita expenditure (PCE) (p = 0.003). After provision of hearing aids, median household income improved among cases (p = 0.03). In the comparison group, median individual income (p = 0.01) and PCE (p = 0.03) fell between baseline at follow-up. At follow-up, there were also improvements in productive time use, quality of life, and depressive symptoms among cases, but these were less apparent in the comparison group. In conclusion, this study has demonstrated a positive effect of hearing aids in improving quality of life, economic circumstances and mental health among Guatemalan adults.

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A Retrospective Chart Review of 122 Inpatients with Knee Osteoarthritis Treated with Korean Medicine: An Analysis of the Effects of Treatment

Journal of Acupuncture Research ◽

10.13045/jar.2021.00087 ◽

2021 ◽

Vol 38 (3) ◽

pp. 205-218

Author(s):

Dong-Hwi Yoo ◽

Han-Bin Park ◽

Won-Suk Jang ◽

Oh-Bin Kwon ◽

Ki-Won Choi ◽

...

Keyword(s):

Quality Of Life ◽

Body Mass Index ◽

Knee Osteoarthritis ◽

Body Mass ◽

Index Hospitalization ◽

Korean Medicine ◽

Knee Oa ◽

Hospitalization Period ◽

Before And After

Background: Korean medicine treatment was assessed in patients with knee osteoarthritis (OA) according to subgroups of: sex, age, cause of knee OA, body mass index, hospitalization period, history, OA compartment, phenotype, and comorbidity. Methods: A retrospective review was performed of 122 inpatients who were admitted to the Hospital of Korean Medicine for Korean medicine treatment of knee pain, and were diagnosed with knee OA based on magnetic resonance imaging findings. Analysis of patient subgroups (sex, age, cause of knee OA, body mass index, hospitalization period, history, OA compartment, phenotype, and comorbidity) was carried out and treatments including acupuncture, cupping, pharmacopuncture, herbal medicine, chuna therapy, medicinal steaming therapy, manual therapy, and extracorporeal shock wave therapy were listed. The numeric rating scale (NRS), Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC), and 5-level EuroQol- 5 Dimension (EQ-5D-5L) scores were measured before and after treatment to assess the effects of treatment on pain and quality of life. Results: Seventeen males and 105 females were included in this study. Most patients were in their 60s. In the total study population, NRS, WOMAC, and EQ-5D-5L scores were improved statistically significant when comparing before and after treatment. The NRS and WOMAC scores improved statistically significant in the medial, patellofemoral, medial + patellofemoral, medial + lateral + patellofemoral compartment. Conclusion: Korean medicine treatment significantly reduced pain, stiffness, and physical dysfunction, and improved the quality of life of patients with knee OA, suggesting that it may be an effective alternative to the current conservative treatments.

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Elosulfase Alfa Treatment in Morquio A Patients in Iran: A Before and After Study

Iranian Journal of Pediatrics ◽

10.5812/ijp.111562 ◽

2021 ◽

Vol In Press (In Press) ◽

Author(s):

Mohammadreza Alaei ◽

Marjan Shakiba ◽

Hedyeh Saneifard ◽

Ghamartaj Khanbabaee ◽

Mohammadreza Khalilian ◽

...

Keyword(s):

Quality Of Life ◽

Standard Dose ◽

Lysosomal Storage ◽

Morquio A ◽

Before And After ◽

The Impact ◽

Before And After Study ◽

Morquio A Syndrome ◽

Elosulfase Alfa

Background: Morquio A, an autosomal recessive lysosomal storage disease, is caused by a defect in the enzyme N-acetyl-galactosamine-6-sulfatase. This leads to the accumulation of the glycosaminoglycans chondroitin-6-sulfate (C6S) and keratan sulfate (KS), resulting in various skeletal manifestations, multisystemic impairments, and significant morbidities. Objectives: This study aimed to evaluate the impact of the addition of elosulfase alfa to the hospital protocol on treating Iranian pediatricians with Morquio A syndrome. Methods: A before and after study was conducted on ten patients with Morquio A syndrome diagnosis from 2019 to 2020. Elosulfase alfa was prescribed with the standard dose of 2 mg/kg/weekly IV infusion for 54 weeks. Then, growth indices, quality of life, and cardiopulmonary data were collected by research assistants using a pre-designed check. Data were entered in SPSS version 23. Quantitative variables were compared between the two periods using the Student's t-test, and qualitative variables were compared using the χ2 test or Fisher's exact test. Results: Ten pediatricians with MPS IV were included, seven of whom were female, with the mean age of 5.8 ± 2.3 years. The meantime for walking 6 m (P = 0.005), standing (P = 0.005), the stair climb test (P = 0.007), and quality of life (P = 0.015) had significant statistical difference before and after treatment by elosulfase alfa. Conclusions: The addition of elosulfase alfa in patients with Morquio A syndrome was associated with a significant improvement outcome in the ‘after’ treatment period.

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