scholarly journals The Impact of Rope Jump Exercise Training on Hemolytic Anemia Parameters in Obese Adolescent Boys

2021 ◽  
Vol In Press (In Press) ◽  
Author(s):  
Hossein TaheriChadorneshin ◽  
Somayeh Nazari

Background: One of the theories about hemolytic anemia concerns foot-strike on the ground. Rope jump exercise training (RJET) is performed with high foot-strike repetitions on the ground. Objectives: This paper aimed to study the possible effect of RJET on hematological parameters involved in hemolysis. Methods: Twenty obese adolescent boys with a mean age of 13.40 ± 1.09 years were allocated into two equal groups of control and RJET (n = 10 each). The RJET group performed simple rope jumping for eight weeks (three days a week). Blood samples were collected before and after the protocol. Independent t-test and Mann-Whitney U test were used for data analysis. Results: Our findings showed no significant inter-group differences for erythrocyte, platelet, and leukocyte parameters. However, given the effect of time, a significant reduction was observed in monocyte count in the RJET group. In contrast, eosinophil count significantly increased after RJET. Conclusions: According to the results, foot striking induced by RJET had no adverse effect on hemolytic anemia in obese adolescent boys.

2014 ◽  
Vol 307 (3) ◽  
pp. H418-H425 ◽  
Author(s):  
Ralph R. Scholten ◽  
Marc E. A. Spaanderman ◽  
Daniel J. Green ◽  
Maria T. E. Hopman ◽  
Dick H. J. Thijssen

Blood flow patterns in conduit arteries characterized by high levels of retrograde shear stress can be detrimental for vascular health. In this study we examined whether retrograde shear rate and endothelial function are related in healthy and formerly preeclamptic (PE) women and whether this relationship is altered by exercise training. Formerly PE women (32 ± 4 yr, n = 20) and controls (32 ± 4 yr, n = 20), all 6–12 mo postpartum, performed 12-wk aerobic exercise training. We measured brachial artery shear rate (SR) and endothelial function by flow-mediated dilation (FMD, echo-Doppler). We additionally performed power spectral analysis of heart rate variability and calculated low-frequency/high-frequency (LF/HF) ratio. Antegrade SR was not different between groups, while retrograde SR was significantly higher and FMD% lower in PE women compared with controls (both P < 0.05). Retrograde shear correlated strongly with FMD% in PE women and controls ( P < 0.05). LF/HF ratio inversely correlated with brachial artery retrograde SR and FMD% (both P < 0.05) in PE women and controls. Exercise training reduced retrograde shear, improved FMD%, and reduced LF/HF ratios similarly in both groups (all P < 0.05). Training-induced changes in retrograde SR correlated with changes in FMD% and LF/HF ratio. A higher brachial artery retrograde SR relates to lower brachial artery endothelial function, in both controls and formerly PE women. Exercise training improves retrograde SR, while the magnitude of this change correlated strongly with improvements in FMD and reductions in LF/HF ratio. Therefore, the impact of PE and exercise training on endothelial health may, at least partly, be related to retrograde shear rate.


2020 ◽  
Vol 36 (5) ◽  
Author(s):  
Rahma Mohammad Alyami ◽  
Abdulrahman Mohammed Alhwaikan ◽  
Abdullah Rashed Alharbi ◽  
Ghada AL-Nafisah

Objectives: To assess the impact of supervised exercise training (SET) on pulmonary function Parameters, exercise capacity and Irisin biomarker in Interstitial Lung Disease (ILD) patients. Methods: Ten (10) patients with ILD and 18 healthy controls of age between 30-40+ years were selected for 8-weekSET program. Before and after SET all subjects performedexercise capacity six minutes’ walk test (6MWT), heart rate (HR) changes were recorded, shortness of Breath Respiratory Questionnaire (SOBQ) was obtained and Irisin levels were measuredby Enzyme-Linked Immunosorbent Assay (ELISA).This interventional study was carried out atDepartment of Physiology, Faculty of Medicine, King Khalid University Hospital, King Saud University, Riyadh, Saudi Arabia, from October 2018 to February 2019. Results: Mean six minutes’ walk distance (6MWD) was 395±68.4 m at 1st visit increased significantly (p=0.001) to 458.8±87.1 mat 15 visit. However, 6MWD values found significantly higher in controls (517.4±84.1 m; 561.7±81.6 m; p=0.013) thanILD patients. Overall change (difference between post and pre exercise) in HRvalue was recorded lower in ILD patients (30-35 bpm) as compared to controls (40-45 bpm). Moreover, ILD patients had overall higher SOBQ score than controls. Pre SET Irisin levelsofILD patients (4.24 ± 1.73 pg/ml) and controls (3.43±1.04pg/ml) werefound unchangedafter SET (4.48±2.02pg/ml, 3.39 ±1.41pg/ml,p=0.677, p=0.093) respectively. However, patients Irisin values were foundhigher as compared to controls before and after SET. Conclusion: Exercise capacity and Dyspneain patients with ILD were improved after 8-week of SET program. No major changes in Irisin levels among patients with ILD and controls were observed. Additional research requires to be carried out on large number of subjects to deterMinutese the advantages of exercise in ILD. doi: https://doi.org/10.12669/pjms.36.5.1795 How to cite this:Alyami RM, Alhwaikan AM, Alharbi AR, AL-Nafisah G. Impact of supervised exercise training on pulmonary function parameters, exercise capacity and Irisin Biomarker in Interstitial lung disease patients. Pak J Med Sci. 2020;36(5):1089-1095.  doi: https://doi.org/10.12669/pjms.36.5.1795 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


2019 ◽  
Vol 2019 ◽  
pp. 1-8 ◽  
Author(s):  
Steven K. Malin ◽  
Nicole M. Gilbertson ◽  
Natalie Z. M. Eichner ◽  
Emily Heiston ◽  
Stephanie Miller ◽  
...  

Introduction. The impact of interval (INT) vs. continuous (CONT) exercise training on endothelial function in relation to glucose metabolism prior to clinically meaningful weight loss is unknown in adults with prediabetes. Methods. Twenty-six subjects with prediabetes (60±1 y; 33±1 kg/m2; 2-hr-PG OGTT: 145±7 mg/dl) were randomized to 60 min of CONT (n=12; 70% of HRpeak) or work-matched INT exercise training (n=14; alternating 3 min at 90 and 50% HRpeak) for 2 weeks. Aerobic fitness (VO2peak) and body composition (bioelectrical impedance) were assessed before and after training. Flow-mediated dilation (FMD) was measured during a 2 h 75 g OGTT (0, 60, and 120 min) to assess endothelial function. Postprandial FMD was calculated as incremental area under the curve (iAUC). Glucose tolerance and insulin were also calculated by iAUC. Fasting plasma VCAM, ICAM, and hs-CRP were also assessed as indicators of vascular/systemic inflammation. Results. Both interventions increased VO2peak (P=0.002) but had no effect on body fat (P=0.20). Although both treatments improved glucose tolerance (P=0.06) and insulin iAUC (P=0.02), VCAM increased (P=0.01). There was no effect of either treatment on ICAM, hs-CRP, or fasting as well as postprandial FMD. However, 57% of people improved fasting and iAUC FMD following CONT compared with only 42% after INT exercise (each: P=0.04). Elevated VCAM was linked to blunted fasting FMD after training (r=−0.38, P=0.05). But, there was no correlation between fasting FMD or postprandial FMD with glucose tolerance (r=0.17, P=0.39 and r=0.02, P=0.90, respectively) or insulin iAUC following training (r=0.34, P=0.08 and r=0.04, P=0.83, respectively). Conclusion. Endothelial function is not improved consistently after short-term training, despite improvements in glucose and insulin responses to the OGTT in obese adults with prediabetes.


2017 ◽  
Vol 17 (3) ◽  
pp. 104-108
Author(s):  
Hasan Huseyin Eker ◽  
Mehmet Derya Onuk ◽  
Caglayan Geredeli ◽  
Maihebureti Abuduli

I'tikaaf is a worship maintained by very deep hunger in fasting month of Ramadan. Hunger causes different results on the immune system. This is a prospective study. In this study, the changes in the immune system were investigated during the period of the i’tikaf, which is deep hunger worship. In the last 10 days of Ramadan, before and at the end of i’tikaf blood was taken from 46 male volunteers who performed i’tikaf worship and various biochemical and immunological parameters were examined. Comparison of the measures taken before and after i’tikaf indicated a statistically significant decrease in weight, BMI, waist circumference and hip circumference (p<0.001). Of the hematologic parameters, the lymphocyte count increased significantly (p=0.009). Also, a significant increase was observed in the values of IgA, IgM ve Ig G within the hematological parameters (p<0.001). During the period of i’tikaf, feeding with very low calories (1000 calories) caused an increase in the levels of lymphocyte and immunoglobulins and got the immune system stronger.


2021 ◽  
Vol 38 (3) ◽  
pp. 308-311
Author(s):  
Vijayashri Basavaraj HANCHINAL ◽  
Ambhuja SAMBRANI ◽  
Vineet BALJOSHI

Menstruation is the most common phenomenon observed in fertile women. Menstrual cycle (MC) is of 3 phases: proliferative phase, secretory phase and menstruation phase. It is controlled by endocrine system. Natural fluctuations in sex steroid hormones during MC causes changes in hematological parameters. The aim of the present study to assess the impact of different phases of MC on hematological parameters. The study was conducted in KIMS, Hubli, from 01st March 2011 to 31st March 2012. Women aged between 20-30 years with regular menstrual cycle of 27-30 days were included in the study. During each visit, the subjects’ blood was collected and analyzed using KX-21 SYSMEX for various hematological parameters. A total of 50 healthy young women were included in the study. On statistical comparing of hematological parameters, hematocrit, hemoglobin, neutrophil count and eosinophil count showed a significant difference while no statistically significant difference was observed in RBC, leucocyte count, lymphocyte count, monocyte count, erythrocyte sedimentation rate (ESR) and platelet count between different phases of MC. To conclude, the hematological parameters during the MC are highly dependent on the phasic changes in the immune response mechanism and sex steroid hormones.


2020 ◽  
Vol 29 (158) ◽  
pp. 200053
Author(s):  
Emily Hume ◽  
Lesley Ward ◽  
Mick Wilkinson ◽  
James Manifield ◽  
Stephen Clark ◽  
...  

Exercise intolerance and impaired quality of life (QoL) are characteristic of lung transplant candidates and recipients. This review investigated the effects of exercise training on exercise capacity, QoL and clinical outcomes in pre- and post-operative lung transplant patients.A systematic literature search of PubMed, Nursing and Allied Health, Cochrane (CENTRAL), Scopus and CINAHL databases was conducted from inception until February, 2020. The inclusion criteria were assessment of the impact of exercise training before or after lung transplantation on exercise capacity, QoL or clinical outcomes.21 studies met the inclusion criteria, comprising 1488 lung transplant candidates and 1108 recipients. Studies consisted of five RCTs, two quasi-experimental and 14 single-arm cohort or pilot studies. Exercise training improved or at least maintained exercise capacity and QoL before and after lung transplantation. The impact on clinical outcomes was less clear but suggested a survival benefit. The quality of evidence ranged from fair to excellent.Exercise training appears to be beneficial for patients before and after lung transplantation; however, the evidence for direct causation is limited by the lack of controlled trials. Well-designed RCTs are needed, as well as further research into the effect of exercise training on important post-transplant clinical outcomes, such as time to discharge, rejection, infection, survival and re-hospitalisation.


2012 ◽  
Vol 108 (11) ◽  
pp. 824-831 ◽  
Author(s):  
Roman Nowobilski ◽  
Katarzyna Kusinska ◽  
Karolina Bukowska-Strakova ◽  
Rafal Nizankowski ◽  
Witold Nowak ◽  
...  

SummaryExercise training remains a therapy of choice in intermittent claudication (IC). However, too exhaustive exercise may cause ischaemic injury and inflammatory response. We tested the impact of three-month treadmill training and single treadmill exercise on antioxidant gene expressions, cytokine concentrations and number of marrow-derived proangiogenic progenitor cells (PPC) in the blood of IC patients. Blood samples of 12 patients were collected before and after training, before and 1, 3 and 6 hours after the single exercise. PPCs were analysed with flow cytometry, cytokine concentrations were checked with Milliplex MAP, while expression of mRNAs and miRNAs was evaluated with qRT-PCR. Treadmill training improved pain-free walking time (from 144 ± 44 seconds [s] to 311 ± 134 s, p=0.02) and maximum walking time (from 578 ± 293 s to 859 ± 423 s, p=0.01) in IC patients. Before, but not after training, the single treadmill exercise increased the number of circulating CD45dimCD34+CD133-KDR+ PPCs (p=0.048), decreased expression of HMOX1 (p=0.04) in circulating leukocytes, reduced tumour necrosis factor-α (p=0.03) and tended to elevate myeloperoxidase (p=0.06) concentrations in plasma. In contrast, total plasminogen activator inhibitor-1 was decreased by single exercise only after, but not before training (p=0.02). Both before and after training the single exercise decreased monocyte chemoattractant protein (MCP)-1 (p=0.006 and p=0.03) concentration and increased SOD1 (p=0.001 and p=0.01) expression. Patients after training had also less interleukin-6 (p=0.03), but more MCP-1 (p=0.04) in the blood. In conclusion, treadmill training improves walking performance of IC patients, attenuates the single exercise-induced changes in gene expressions or PPC mobilisation, but may also lead to higher production of some proinflammatory cytokines.


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