scholarly journals Minimal clinically important difference: The basics

Medwave ◽  
2021 ◽  
Vol 21 (03) ◽  
pp. e8149-e8149
Author(s):  
Julieta Aldana Salas Apaza ◽  
Juan Víctor Ariel Franco ◽  
Nicolás Meza ◽  
Eva Madrid ◽  
Cristobal Loézar ◽  
...  

This article is part of a collaborative methodological series of narrative reviews on biostatistics and clinical epidemiology. This review aims to present basic concepts about the minimal clinically important difference and its use in the field of clinical research and evidence synthesis. The minimal clinically important difference is defined as the smallest difference in score in any domain or outcome of interest that patients can perceive as beneficial. It is a useful concept in several aspects since it links the magnitude of change with treatment decisions in clinical practice and emphasizes the primacy of the patient’s perception, affected by endless variables such as time, place, and current state of health, all of which can cause significant variability in results.

2021 ◽  
pp. 149-160
Author(s):  
Fiona F. Stanaway ◽  
Naomi Noguchi ◽  
Clement Loy ◽  
Sharon Reid ◽  
Jonathan C. Craig

Clinical epidemiology is a science that extends the principles and methods of epidemiology to clinical practice and clinical research. In this chapter, we provide an overview of clinical epidemiological methods and how these approaches can be used to improve global public health. We have focused primarily on using evidence in decision-making in this chapter, rather than study design and conduct elements, such as randomized controlled trials, which are covered in detail elsewhere. Consequently, we have provided a framework for critical appraisal and reporting of relevant study designs (how to use and report), rather than a detailed discussion about how such studies should be designed and conducted (how to do).


Author(s):  
Alicia Clair

A description of the current state of music therapy research with those who have dementia and the future of music therapy in dementia care is provided in this chapter. The contents stem from many years of experience as a board-certified music therapist with those who have dementia and their care givers, and it culminates learning from clinical practice and research in the development of a theoretical framework and practice knowledge. Deep appreciation is expressed for all care receivers, and their care givers, who allowed music therapy to become part of their lives and who consented to participate in the development of knowledge to share with others. This chapter provides: (a) A review of selected clinical research studies in music therapy and dementia care, (b) updated dementia information that has implications for current music therapy practice, (c) a theoretical framework for music therapy, and (d) the theoretical principles that guide clinical music therapy practice with care receivers and caregivers.


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