scholarly journals Correlation between hemoglobin and hematocrit results obtained on full blood count and blood gas analysis in children

Author(s):  
Viviane M. Bernardes ◽  
Fernanda N. Anderle ◽  
Karine dos Anjos ◽  
Christian Boller

The chapter aims to provide a brief but thorough reference for the commonest urine and blood tests that medical students will encounter on the wards and in clinic. The chapter focuses in detail on the wealth of information provided by a simple urine dip, including signs of infection, haematuria, pregnancy (or ectopic pregnancy), and metabolic disorders. The chapter discusses in detail how to read a full blood count which can give clues not only to infection but also to chronic infection, leukaemias, parasites, allergy, iron deficiency, and many other disease processes. The chapter also discusses the use of the reticulocyte count to help differentiate between haemolytic anaemias (raised) and bone marrow failure (decreased, e.g. from cancer). A guide to findings on blood films is also given. The clotting cascade and clotting parameters are summarized. The commonest tests in clinical chemistry, including blood glucose, renal and liver function, and bone profile are also discussed. A guide to blood gas analysis, with common examples, is also covered, along with a systematic approach to electrocardiogram interpretation.


Author(s):  
G.G. Khubulava ◽  
A.B. Naumov ◽  
S.P. Marchenko ◽  
O.Yu. Chupaeva ◽  
A.A. Seliverstova ◽  
...  

Author(s):  
Elisabetta Colciago ◽  
Simona Fumagalli ◽  
Elena Ciarmoli ◽  
Laura Antolini ◽  
Antonella Nespoli ◽  
...  

Abstract Purpose Delayed cord clamping for at least 60 s is recommended to improve neonatal outcomes. The aim of this study is to evaluate whether there are differences in cord BGA between samples collected after double clamping the cord or without clamping the cord, when blood collection occurs within 60 s from birth in both groups. Methods A cross-sectional study was carried out, collecting data from 6884 high-risk women who were divided into two groups based on the method of cord sampling (clamped vs unclamped). Results There were significant decrease in pH and BE values into unclamped group compared with the clamped group. This difference remained significant when considering pathological blood gas analysis parameters, with a higher percentage of pathological pH or BE values in the unclamped group. Conclusion Samples from the unclamped cord alter the acid–base parameters compared to collection from the clamped cord; however, this difference does not appear to be of clinical relevance. Findings could be due to the large sample size, which allowed to achieve a high power and to investigate very small numerical changes between groups, leading to a statistically significant difference in pH and BE between samples even when we could not appreciate any clinical relevant difference of pH or BE between groups. When blood gas analysis is indicated, the priority should be given to the timing of blood collection to allow reliable results, to assess newborns status at birth and intervene when needed.


1934 ◽  
Vol 104 (1) ◽  
pp. 29-31
Author(s):  
Friedrich Rappaport ◽  
Klara Köck-Molnar

2021 ◽  
pp. 039139882098785
Author(s):  
Lawrence Garrison ◽  
Jeffrey B Riley ◽  
Steve Wysocki ◽  
Jennifer Souai ◽  
Hali Julick

Measurements of transcutaneous carbon dioxide (tcCO2) have been used in multiple venues, such as during procedures utilizing jet ventilation, hyperbaric oxygen therapy, as well as both the adult and neo-natal ICUs. However, tcCO2 measurements have not been validated under conditions which utilize an artificial lung, such cardiopulmonary bypass (CPB). The purpose of this study was to (1) validate the use of tcCO2 using an artificial lung during CPB and (2) identify a location for the sensor that would optimize estimation of PaCO2 when compared to the gold standard of blood gas analysis. tcCO2 measurements ( N = 185) were collected every 30 min during 54 pulsatile CPB procedures. The agreement/differences between the tcCO2 and the PaCO2 were compared by three sensor locations. Compared to the earlobe or the forehead, the submandibular PtcCO2 values agreed best with the PaCO2 and with a median difference of –.03 mmHg (IQR = 5.4, p < 0.001). The small median difference and acceptable IQR support the validity of the tcCO2 measurement. The multiple linear regression model for predicting the agreement between the submandibular tcCO2 and PaCO2 included the SvO2, the oxygenator gas to blood flow ratio, and the native perfusion index ( R2 = 0.699, df = 1, 60; F = 19.1, p < 0.001). Our experience in utilizing tcCO2 during CPB has demonstrated accuracy in estimating PaCO2 when compared to the gold standard arterial blood gas analysis, even during CO2 flooding of the surgical field.


1972 ◽  
Vol 2 (18) ◽  
pp. 997-999
Author(s):  
N. B. Pinkus ◽  
B. MacC. Jones ◽  
L. W. Faulks

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