scholarly journals Quality of life of patients with gynecological cancers

2020 ◽  
Vol 7 (3) ◽  
pp. 991-997
Author(s):  
Maria Kilikova

Introduction: The quality of a women's life is very closely related to their health. Oncogynecological disease brings substantial changes into their life that women need to adapt to them. As determination of quality of life is in nurse competence, the quality of life in women with diagnosed oncogynecological illness and surgical treatment has been described in the paper. Aim: The aim of the paper was to examine cancer's influence on the quality of life based on physical health, survival, social relationships, and the environmental domains. Methods: The sample consisted of 84 female respondents with surgical treatment of oncogynecological disease and the patients fulfilled the standardized WHOQOL-BREF questionnaire. Results: The results have shown that patients experienced significant reductions in the quality of life in regard to physical and mental health. Social and environmental domain were significantly less affected. Conclusions: The oncogynecoogical diseases significantly affect quality of life in all four investigated domains, but to a different extent. These findings emphasize an individual approach that takes into account not only the nursing aspect but also the ability to respond to a variety of other related factors that affect the quality of women with oncogynecological disease.

2021 ◽  
Vol 19 (1) ◽  
Author(s):  
Fatemeh Nouri ◽  
Awat Feizi ◽  
Hamidreza Roohafza ◽  
Masoumeh Sadeghi ◽  
Nizal Sarrafzadegan

Abstract Background and objectives A short form of the General Health Questionnaire (GHQ-12) is a useful screening instrument for assessing mental health. Furthermore, Quality of life (QoL) is a critical treatment outcome in many clinical and health care research settings. This study aimed to reassess the dimensionality of GHQ-12 using Multidimensional Graded Response Model (MGRM) and evaluate how its extracted dimensions are associated with the QoL's domains. Methods Isfahan Cohort Study 2 (ICS2) is a population-based, ongoing prospective cohort study among adults aged 35 years and older who were free of cardiovascular diseases (CVDs) at the beginning of the study in 2013. A total of 1316 participants, all living in urban and rural areas of Isfahan and Najafabad, Iran was completed the GHQ-12 and WHO QoL-brief version at baseline. Five competing MGRMs with different latent structures were specified for GHQ-12. Factor scores derived from the best fitted model were used to associate with various domains of QoL. Results: The Three-Dimensional model for GHQ-12 was the best-fitted model explaining the Social Function (SF), Self Confidence (SC), and Anxiety/Depression (A/D) as three correlated yet different latent dimensions of mental health. Our findings in full adjusted multivariate regression models showed that a one-SD increase in dimensions of SC and SF was associated with a 38- to 48%-SD and 27- to 38%-SD increase in the domains scores of QoL, respectively. Moreover, for each one‐SD increase in score of A/D dimension, the domains scores of QoL decreased by 29- to 40%-SD. The highest to the lowest standardized coefficients for all latent dimensions of mental health were respectively related to the psychological, physical health, social relationships, and environmental condition domains of QoL. Furthermore, SC, A/D, and SF dimensions of GHQ-12 showed the highest to the lowest degree of association with all domains of QoL. Conclusions Our findings confirm that the GHQ-12 as a multidimensional rather than unitary instrument measures distinct dimensions of mental health. Furthermore, all aspects of QoL changed when the intensity of latent dimensions of mental health increased. Moreover, the psychological domain of QoL is the most affected by all latent dimensions of mental health, followed by physical health, social relationships, and environmental condition domains. It seems that in an attempt to full recovery as assessed by improved QoL outcomes, treatment of clinical symptoms may not be sufficient. Identifying and differentiating the structures of mental health in each community as well as implementing intervention programs aimed at focusing on specific dimensions may help in the prevention of further deterioration of mental health and improved QoL in the community.


Author(s):  
Robert Brackbill ◽  
Howard Alper ◽  
Patricia Frazier ◽  
Lisa Gargano ◽  
Melanie Jacobson ◽  
...  

Fifteen years after the disaster, the World Trade Center Health Registry (Registry) conducted The Health and Quality of Life Survey (HQoL) assessing physical and mental health status among those who reported sustaining an injury on 11 September 2001 compared with non-injured persons. Summary scores derived from the Short Form-12 served as study outcomes. United States (US) population estimates on the Physical Component Score (PCS-12) and Mental Component Score (MCS-12) were compared with scores from the HQoL and were stratified by Post-traumatic Stress Disorder (PTSD) and injury status. Linear regression models were used to estimate the association between both injury severity and PTSD and PCS-12 and MCS-12 scores. Level of injury severity and PTSD history significantly predicted poorer physical health (mean PCS-12). There was no significant difference between injury severity level and mental health (mean MCS-12). Controlling for other factors, having PTSD symptoms after 9/11 predicted a nearly 10-point difference in mean MCS-12 compared with never having PTSD. Injury severity and PTSD showed additive effects on physical and mental health status. Injury on 9/11 and a PTSD history were each associated with long-term decrements in physical health status. Injury did not predict long-term decrements in one’s mental health status. Although it is unknown whether physical wounds of the injury healed, our results suggest that traumatic injuries appear to have a lasting negative effect on perceived physical functioning.


2020 ◽  
Vol 13 (2) ◽  
pp. 119-128
Author(s):  
Kirill Kosilov ◽  
Hiroki Amedzawa ◽  
Irina Kuzina ◽  
Vladimir Kuznetsov ◽  
Liliya Kosilova

Aim: The study of the impact of socio-economic, demographic factors and polymorbidity on the quality of life associated with health (HRQoL) in elderly people from Japan and Russia. Background: Factors affecting the quality of life of the elderly in both countries are poorly understood. Objective: Make a comparative analysis of factors affecting the quality of life of the elderly of both sexes in Japan and Russia. Methods: The age range in this study is 65-95 years old. For the study of HRQoL, a questionnaire Health Status Survey-Short Form 36v2 was used, including two main domains: physical and mental health. The level of polymorbidity was studied using CIRS-G. The linear regression model of the influence of variables upon HRQoL was calculated for SES, demographic characteristics, and morbidity. Results: Strong associations with HRQoL in the combined sample had a living together with relatives (r=6.94 (5.17-8.72) p<0,05), the incidence rate (r=8.50 (5.51-11.49), p<0.01) and the older age (r=5.39 (2.63-8.16), p<0,01.). The elderly inhabitants of Japan had a higher self-assessment for physical health in the age ranges 65-74 and over 85 years old (p<0.05), and a higher selfassessment of mental health at the age of 75-84 years old. Sixty-eight elderly Japanese and 48% Russians estimated their physical health as normal. Conclusion: The effect of living together, morbidity and age upon HRQoL is manifested equally strongly both among the inhabitants of Japan and among the Russians. The elderly Japanese estimate the state of physical and mental health as a whole higher than their Russian peers.


2020 ◽  
Vol 16 (2) ◽  
pp. 132-137
Author(s):  
Mohammad Vafaee-Shahi ◽  
Mehrnoosh Purfallah ◽  
Elham Shirazi ◽  
Samileh Noorbakhsh

Background & Aim: Attention deficit hyperactivity disorder (ADHD) is the most common mental health disorder among young children that affects the mothers’ lifestyles The aim of the present study was to consider the quality of life in Iranian mothers with ADHD children. Objective: In this comparative study, we compared the quality of life between mothers of ADHD children and mothers of normal children. Methods: In this descriptive study (2018-2019), a total of 75 mothers with ADHD children and 75 mothers with normal children, who were referred to referral educational hospital (Rasoul Hospital; Tehran, Iran) were evaluated. ADHD criteria were assessed by means of the SNAP-IV questionnaire, while the quality of life was evaluated by the SF-36 questionnaire. All data were analyzed by SPSS software. The environmental, mental, social physical, health and quality of life were compared between 2 groups. Results: The economic situation of mothers with normal children was average (73.3%) to good (16%), while in mothers with ADHD children the economic situation was average (45.3%) to poor (37.3%). Mothers’ employment in normal children group was 41.3%, but it was 14.6% in mothers with ADHD children. A significant difference was reported between two groups in the mean of environmental health score (p <0.05), social relationships (p <0.05), mental health (p <0.05), physical health (p <0.01) and quality of life (p <0.01). The mean score of environmental health, social relationships, mental health, physical health and quality of life in ADHD mothers was significantly lower than mothers with normal children. Conclusion: The difficulties in the management of ADHD children negatively affect the quality of mothers’ lifestyles. Therefore, preventive, educational and therapeutic interventions are recommended to improve the mental health and the quality of life of mothers.


Medicina ◽  
2007 ◽  
Vol 43 (9) ◽  
pp. 736 ◽  
Author(s):  
Daina Krančiukaitė ◽  
Daiva Rastenytė ◽  
Kristina Jurėnienė ◽  
Diana Šopagienė

The aim of the study was to compare the quality of life among stroke survivors and healthy controls and to evaluate the influence of age, sex, and social and demographic factors on the quality of life. Contingent and methods. The case group consisted of 508 inhabitants of Kaunas city who were 25–84 years of age and had experienced their first stroke. The control group consisted of age- and sex-stratified randomly selected 508 stroke-free inhabitants of Kaunas city. The quality of life was evaluated using the SF- 12 questionnaire. The study compared the quality of life between stroke survivors and controls in eight domains of quality of life and compared the evaluation of quality of life considering social and demographic features. Results. In the domain of physical and mental health, stroke survivors presented poorer evaluation of their quality of life compared to controls except for the evaluations of mental health in the age groups of 25–34 and 35–44 years. As compared to healthy controls, stroke survivors presented poorer evaluation of their quality of life in all domains except for pain. Only in the control group, females presented poorer evaluation of physical health, whereas no differences in the evaluation of mental health between sexes were found. The evaluation of physical health in both groups worsened with age. Both stroke survivors and controls presented better evaluation of their physical health if they were living not alone, were better educated, and were employed compared to those who were living alone, had poorer education level, and were unemployed. In addition, controls who were currently or previously engaged in mental work evaluated their physical health better. Conclusions. Stroke survivors presented poorer evaluations of their quality of life in both physical and mental health domains compared to controls. Only in the control group, females evaluated their physical health worse than males did. In both groups studied, poorer evaluation of physical health was associated with older age and lower social and demographic status. Relationship between mental health and subjects’ social and demographic status was not statistically significant in either of the studied groups.


2021 ◽  
Vol 11 (4) ◽  
pp. 30-35
Author(s):  
Vladlen V. Bazylev ◽  
Evgeniy V. Nemchenko ◽  
Galina N. Abramova ◽  
Tаtyana V. Kanaeva ◽  
Vаdim A. Karnakhin

Aim. To evaluate long-term quality of life (QOL) of patients after surgical treatment of mitral valve disease depending on the types of surgical intervention, to identify predictors of a lower QOL after surgery. Material and methods. A single-center retrospective study involved 107 patients after isolated correction of primary non-ischemic mitral valve (MV) pathology, who were operated on from 2009 to 2016, and analyzed their long-term QOL. The follow-up period was from 2 to 6 years. 2 groups of patients were formed: the 1st group (n=60) patients who underwent mitral valve replacement (MVR); the 2nd group (n=47) patients who underwent mitral valve repair (MVRep). There were no statistically significant differences between the main clinical and demographic characteristics in reference to the groups. The SF-36 questionnaire was used for studying QOL. Results. The indicators of QOL approach the average population levels in both groups. In group MVRep Physical Functioning PF (p=0.02 and 0.01), Bodily Pain BP (p=0.04), Vitality VT (p=0.01) and Social Functioning SF (p=0.001) are higher. There are improvements in physical and mental health components after surgery. Mental and physical components are lower than in the normal population but they dont go beyond average populations indicators. Mental health in the MVRep group is better than in the MVR group (p=0.01). Female gender, dilatation of the left atrium (every 1 mm before surgery), older age (every year) increased the probability of lower QOL in the long term by 84, 11 and 8% respectively. Conclusion. Long-term QOL of patients after surgical treatment of mitral valve disease improves both after valve repair and after valve replacement. After MVRep Physical Functioning, Bodily Pain, Vitality and Social Functioning indicators are higher. There are improvements in physical and mental health components. Psychological component of health is higher in patients in the MVRep-group. Female gender, dilatation of the left atrium, older age increase the probability of lower QOL in the long term after mitral valve surgery.


2021 ◽  
Vol 5 (Supplement_1) ◽  
pp. 740-740
Author(s):  
Andrea Huseth-Zosel ◽  
Heather Fuller

Abstract The COVID-19 pandemic is a public health crisis the world has not seen in a century, with older adults faced with unique impacts due to their increased vulnerability and need to social distance. This research examines changes in physical and mental health and quality of life among older adults in the upper Midwest during the COVID-19 pandemic. Seventy older adults aged 70-97 participated in three phone interviews (April [Time 1], June [Time 2], and October [Time 3] 2020) focusing on experiences coping with the pandemic and understanding overall changes in well-being. Participants rated their quality of life, physical health, and mental health on a scale from 1 to 5 with 1 being “Poor” and 5 being “Excellent.” Self-reported quality of life, mental health, and physical health initially declined between retrospective pre-COVID and Time 1 scores, with gradual increases seen across all three variables for Time 2 and Time 3 scores. Thematic analysis of qualitative responses for each interview wave identified salient themes of: 1) reduced quality of life, 2) distraction and routine, 3) loss and uncertainty, and 4) resilience and adaptation. The significance and meaning of these themes shifted across each time point. For example, the reduced quality of life theme initially encompassed loss of activities, later shifted to concerns about struggles to maintain relationships, and finally focused on hope for the future. Findings will be discussed in light of the significance of change over time as well as policy and practice implications for older adults.


2018 ◽  
Vol 5 (suppl_1) ◽  
pp. S415-S415 ◽  
Author(s):  
Evan Tzanis ◽  
Surya Chitra ◽  
Marla Curran ◽  
Paul McGovern ◽  
Jordan Hinahara ◽  
...  

Abstract Background The appearance of multidrug-resistant Gram-positive bacteria is a major challenge in clinical care. Omadacycline is the first aminomethylcycline antibiotic (semisynthetic compounds related to tetracyclines) in late-stage clinical development for acute bacterial skin and skin structure infections (ABSSSI), and demonstrates potent in vitro activity against many pathogens. Methods Seven hundred thirty-five patients were enrolled in the OASIS-2 randomized controlled trial comparing omadacycline and linezolid for the treatment of adult subjects with ABSSSI known or suspected to be due to a Gram-positive pathogen, with 368 and 367 enrolled in each group, respectively. Subjects completed the 36-Item Short Form Health Survey Version 2 (SF-36v2), a validated questionnaire on physical and mental health, at both screening and post-treatment evaluation. Results of the SF-36v2 were analyzed in accordance with established norm-based standards for the survey (Ware 2000) for the intention-to-treat population. Results Subjects who received omadacycline experienced a 3.25 point mean improvement in overall physical health (P &lt; 0.001, Figure 1) and reported significant improvements across all but one component parameter of overall physical and mental health, including physical functioning, bodily pain, role physical, vitality, role emotional, mental health, and social functioning (Figure 2). In contrast, while overall physical health improved for subjects who received linezolid, the improvement in vitality, role emotional, mental health, and general health was not significant (Figure 2). Although omadacycline achieved greater increase from baseline than linezolid across all domains analyzed, the difference in scores was not statistically significant at the P &lt; 0.05 level (Figure 1). Conclusion Omadacycline provides significant improvement in the physical component of quality of life over baseline for adult subjects with ABSSSI known or suspected to be due to a Gram-positive pathogen. Although the OASIS-2 trial was neither designed nor powered to measure differences in quality of life following treatment, trends identified in this analysis merit further investigation. References 1. Ware JE. SF-36 Health Survey Update. SPINE 2000; 25(24); 3130–3139. Disclosures E. Tzanis, Paratek Pharmaceuticals: Employee, Salary. M. Curran, Paratek Pharmaceuticals: Employee, Salary. P. McGovern, Paratek Pharmaceuticals: Employee, Salary. J. Hinahara, Paratek Pharmaceuticals: Consultant, Consulting fee. T. Goss, Paratek Pharmaceuticals: Consultant, Consulting fee.


2009 ◽  
Vol 124 (5) ◽  
pp. 692-701 ◽  
Author(s):  
Haomiao Jia ◽  
Erica I. Lubetkin

Objectives. Although numerous studies have examined health-related quality of life (HRQOL) longitudinally, little is known about the impact of seasonality on HRQOL. We examined trend and seasonal variations of population HRQOL. Methods. We used data from the monthly Behavioral Risk Factor Surveillance System (BRFSS). We examined monthly observed mean physically and mentally unhealthy days from January 1993 to December 2006, using the structural time-series model to estimate the trend and seasonality of HRQOL. Results. We found overall worsening physical and mental health during the time period and a significant and regular seasonal pattern in both physical and mental health. The worst physical health was during the winter and the best physical health was during the summer. The mean number of physically unhealthy days in January was 0.63 days higher than in July. The worst mental health occurred during the spring and fall, but the magnitude of the seasonal effect was much smaller. The difference between the best and worst months of mentally unhealthy days was approximately 0.23 days. We found significant differences in unadjusted and season-adjusted unhealthy days in many counties. Conclusions. Our findings can be used to examine time-varying causal factors and the impact of interventions, such as policies designed to improve population health. Our findings also demonstrated the need for calculating season-adjusted HRQOL scores when examining cross-sectional factors on the population HRQOL measures for continuous surveys or longitudinal data.


2018 ◽  
Vol 5 (2) ◽  
pp. 81-84
Author(s):  
Rajani Shrestha

Introductions: Osteoarthritis (OA) is a non-inflammatory degenerative disorder of the joint. It has negative impact on health related quality of life (QOL), both in physical and mental health. This study aimed to assess QOL of patient with knee osteoarthritis. Methods: A descriptive cross-sectional study was conducted in outpatient department of orthopedic in Patan hospital, Patan Academy of Health Sciences. Non-probability purposive sampling technique was used. Data was collected from 21st July to 18th August 2017 among 125 knee osteoarthritis patients by face-to-face interview using structured interview. Results: Overall QOL of patients with knee osteoarthritis was good in mental health component mean score (62.09) and poor in physical health with a mean score of (38.18). The physical component of QOL was significantly associated with age (p<0.04) and occupation (p<0.001). There was no association between independent variable and mental component of QOL. Conclusions: The significant proportion of the patients have poor quality of life in physical health component, but majority of patients have good mental health.


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