Platelet Rich Plasma & Platelet Rich Fibrin: Dental Applications

2016 ◽  
Vol 4 (1) ◽  
pp. 44
Author(s):  
Prashanth Kumar Katta
Author(s):  
Vinayaka Ambujakshi Manjunatha ◽  
Ankitha Anil Jadhav ◽  
Chaitanya Sree Chalichamala ◽  
Annavarapu Sahithi ◽  
Harsha Madakaripura Dasegowda

Platelet analogues (PA; platelet rich plasma and platelet rich fibrin) are autologous bioactive compounds that have a wide range of medical and dental applications, including periodontal, maxillofacial, Plastic surgery and sports medicine. The aim of these technologies is to collect all the constituents of a patient's blood sample so that they can be used to promote tissue regeneration and improve healing. Since 1954, PA has come a long way. Periodontology and implant dentistry have both benefited from the use of PAs. However, the non-standard preparation technique, processing time, transfer of concentrates, centrifugation temperature, vibration, etc. are all variables that contribute to the various results described in the literature. This study will retrace the evolution of PAs, their preparation procedures, their clinical and technological characteristics and their uses.


2021 ◽  
Vol 14 (3) ◽  
pp. e240203
Author(s):  
Arun Mayya ◽  
Shruti Bhandary ◽  
Advith Kolakemar ◽  
Ann Mary George

The management of necrotic immature permanent teeth has always been a challenge to endodontists. Various treatment modalities have been tried and tested for achieving a successful outcome. Revascularisation is one among these treatment options, which is gaining widespread attention among endodontists. The growing body of evidence demonstrating the success of revascularisation has led to different variations of this treatment option. Clinicians have over time used different scaffolds such as blood clot, collagen, platelet-rich fibrin (PRF) and platelet-rich plasma for revascularisation. This case report outlines the management of immature maxillary central incisors with pulp necrosis and large periapical lesions in a 19-year-old female patient with a modified technique of revascularisation by combining PRF and blood clot. At the end of 12 months, the patient was completely asymptomatic along with regression of the periapical lesions.


2015 ◽  
Vol 42 (6) ◽  
pp. 421-423 ◽  
Author(s):  
Carlos Fernando de Almeida Barros Mourão ◽  
Helder Valiense ◽  
Elias Rodrigues Melo ◽  
Natália Belmock Mascarenhas Freitas Mourão ◽  
Mônica Diuana-Calasans Maia

The use of autologous platelet concentrates, represent a promising and innovator tools in the medicine and dentistry today. The goal is to accelerate hard and soft tissue healing. Among them, the platelet-rich plasma (PRP) is the main alternative for use in liquid form (injectable). These injectable form ofplatelet concentrates are often used in regenerative procedures and demonstrate good results. The aim of this study is to present an alternative to these platelet concentrates using the platelet-rich fibrin in liquid form (injectable) and its use with particulated bone graft materials in the polymerized form.


2015 ◽  
Vol 3 (2) ◽  
pp. 72 ◽  
Author(s):  
Vishnu Ravi Kumar ◽  
Gayathri Gangadharan

<p>The aim of any invasive procedure is the complete eradication and elimination of the infection and associated necrotic tissue followed by repair and regeneration of the affected tissue. In order to achieve this goal various biological products have been introduced, among which are present the platelet concentrates. Platelet concentrates with their higher concentration of platelets has been used in the field of medicine since the 1990s in the form of the first-generation concentrates-Platelet Rich Plasma, and the second generation concentrated -Platelet Rich Fibrin. Choukroun’s Platelet Rich Fibrin is one such material, which is used by itself and also as an adjunct with grafts. It has been successful as it delivers high doses of growth factors and has anti-inflammatory properties. They have been shown to be of great promise in the field of dentistry, ranging from implantology; Sinuses lift procedures, treating of endodontic and periodontal lesions to regeneration of necrotic pulp. This novel technique has the potential to revolutionize the treatment mode in dentistry and help with reducing patient morbidity. We will be further looking into the specification and implications of this material in this review.</p>


2018 ◽  
Vol 6 (2) ◽  
pp. 61 ◽  
Author(s):  
Ronad Al-Azem ◽  
Neveen Ali ◽  
Diana Mostafa

Platelets release several growth factors which stimulate tissue regeneration. Several techniques for platelet concentrates such as platelet rich plasma (PRP), plasma rich in growth factors (PRGF), platelet rich fibrin (PRF) and concentrated growth factors (CGF) have been introduced in dental surgeries for the prevention of hemorrhage and acceleration of tissue regeneration. However, a fabricating growth factors-enriched bone graft matrix which is called “sticky bone” has been demonstrated to provide stabilization in bony defects. In this article, we presented the method of preparing and utilizing CGF and sticky bone and evaluate the effect of CGF mixed with bone graft and CGF barrier membrane in periodontal surgeries.Methodology: We used websites such as PubMed, Scopus, and ISI Web of knowledge to get related articles about this subject. The research process involved specific key words " concentrated growth factor”- “Platelet rich fibrin”- growth factors-enriched bone graft” - “sticky bone” to find more articles which published from 2007 to March 2018.Results: We reviewed 48 articles, 43 articles were excluded. Only five articles have been conducted. Original human studies and case report were included.Conclusion: We concluded that the use of sticky bone and CGF is effective in bone grafting and implant.  


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