Head and Neck Cancers Clinical Practice Guidelines in Oncology

2005 ◽  
Vol 3 (3) ◽  
pp. 316 ◽  
Keyword(s):  
Oral Cavity ◽  
Head And Neck ◽  
The United States ◽  
Head And Neck Cancers ◽  
Second Primary ◽  
Second Primary Neoplasms ◽  
Tobacco Abuse ◽  
Primary Neoplasms ◽  
Recent Version ◽  
Supraglottic Larynx

The NCCN Head and Neck Cancers guidelines address tumors arising in the lip, oral cavity, oropharynx, hypopharynx, glottic and supraglottic larynx, paranasal (ethmoid and maxillary) sinuses, nasopharynx, and salivary glands, as well as occult primary cancer. Approximately 39,250 new cases of oral cavity, pharyngeal, and laryngeal cancers will occur in 2005, which accounts for about 3% of new cancer cases in the United States. An estimated 11,090 deaths from head and neck (H&N) cancers will occur in 2005. Alcohol and tobacco abuse are common etiologic factors in cancers of the oral cavity, oropharynx, hypopharynx, and larynx. Moreover, because the entire aerodigestive tract epithelium may be exposed to these carcinogens, patients with H&N cancer are at risk for developing second primary neoplasms of the H&N, lung, and esophagus. For the most recent version of the guidelines, please visit NCCN.org

The risk of hepatocellular carcinoma in patients with previous malignancy

2007 ◽  
Vol 25 (18_suppl) ◽  
pp. 17075-17075
Author(s):  
A. B. Siegel ◽  
R. B. McBride ◽  
H. El-Serag ◽  
D. Hershman ◽  
L. Zablotska ◽  
...  
Keyword(s):  
United States ◽  
Risk Factors ◽  
Hepatocellular Carcinoma ◽  
Head And Neck ◽  
Kaposi's Sarcoma ◽  
Kaposi’S Sarcoma ◽  
The United States ◽  
Head And Neck Cancers ◽  
Second Primary ◽  
Primary Cancer

17075 Background: Hepatocellular carcinoma (HCC) is one of the most common malignancies in the world. Its incidence has doubled over the past 20 years in the United States. Determination of the pattern of occurrence of HCC as a second primary malignancy might give clues for new risk factors for HCC, or may reveal common genetic or environmental risks. Methods: We identified patients with a diagnosis of a second primary HCC between 1973 and 2002 using the Surveillance, Epidemiology, and End-Results Program (SEER) a compilation of population-based cancer registries in the United States, to calculate the observed to expected (O/E) frequency of second primary HCC after a different primary cancer. We stratified by ethnicity, latency from the year of diagnosis of primary cancer to HCC diagnosis, and period of diagnosis of primary cancer as early (1973–1987) or late (1987–2002). Results: We reviewed 1,931,911 subjects with cancer, and identified 1,185 second primary HCC cases. Overall, a second primary HCC after any primary cancer was less frequent than expected (O/E=0.82, 95% CI=0.77–0.87). We found positive associations with head and neck cancers (oral cavity/pharynx O/E=2.1, 95% CI=1.7–2.5), Kaposi's sarcoma (O/E=3.3, 95% CI=1.2–7.1) and Hodgkin's disease (O/E=2.3, 95% CI=1.2–4.0). Negative associations were seen for breast cancer (O/E=0.7, 95% CI=0.6–0.8), colorectal cancer (O/E=0.6, 95% CI=0.6–0.8), and prostate cancer (O/E=0.7, 95%CI=0.6–0.8). Overall, lower O/E ratios were seen in whites, while in African Americans and those of other races, the O/E ratios were close to one. Latency times were relatively short for head and neck cancers and Kaposi's sarcoma (most within 12–59 months), and greater than 120 months for most cases of HCC after Hodgkin's disease. All cases of Kaposi's sarcoma were seen in the later time period. Conclusions: These results highlight possible shared risk factors of alcohol ingestion and viral exposures which may predispose to second primary HCC after other primary malignancies. Providers should maintain heightened alertness for second primary HCC in these patients, especially those with head and neck cancers and HIV. No significant financial relationships to disclose.

scholarly journals Effectiveness of planned surveillance for detecting second primary head and neck cancers after endoscopic resection of esophageal squamous cell carcinoma

2020 ◽  
Vol 50 (10) ◽  
pp. 1162-1167 ◽  
Author(s):  
Takeshi Shinozaki ◽  
Chikatoshi Katada ◽  
Kiyoto Shiga ◽  
Takahiro Asakage ◽  
Tetsuji Yokoyama ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Esophageal Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Head And Neck ◽  
Endoscopic Resection ◽  
Squamous Cell ◽  
Head And Neck Cancers ◽  
Transoral Surgery ◽  
Second Primary ◽  
Laryngeal Function

Abstract Background Second primary head and neck cancers after endoscopic resection of esophageal squamous cell carcinoma adversely affect patients’ outcomes and the quality of life; however, an adequate surveillance schedule remains unclear. Methods We analyzed 330 patients with early esophageal squamous cell carcinoma who underwent endoscopic resection and were registered in the multicenter cohort study to evaluate adequate surveillance for detection of second primary head and neck cancers. Gastrointestinal endoscopists examined the head and neck regions after 3–6 months of endoscopic resection for esophageal squamous cell carcinoma and subsequently every 6 months. An otolaryngologist also examined the head and neck regions at the time of endoscopic resection for esophageal squamous cell carcinoma and at 12 months intervals thereafter. Results During the median follow-up period of 49.4 months (1.3–81.2 months), 33 second primary head and neck cancers were newly detected in 20 patients (6%). The tumor site was as follows: 22 lesions in the hypopharynx, eight lesions in the oropharynx, two lesions in larynx and one lesion in the oral cavity. The 2-year cumulative incidence rate of second primary head and neck cancers was 3.7%. Among them, 17 patients with 29 lesions were treated by transoral surgery. One patient with two synchronous lesions was treated by radiotherapy. Two lesions in two patients were not detected after biopsy. All patients were cured with preserved laryngeal function. Conclusions Surveillance by gastrointestinal endoscopy every 6 months and surveillance by an otolaryngologist every 12 months could detect second primary head and neck cancers at an early stage, thereby facilitating minimally invasive treatment.

scholarly journals Herpesviruses in Head and Neck Cancers

Viruses ◽  
2020 ◽  
Vol 12 (2) ◽  
pp. 172 ◽  
Author(s):  
Mikołaj Wołącewicz ◽  
Rafał Becht ◽  
Ewelina Grywalska ◽  
Paulina Niedźwiedzka-Rystwej
Keyword(s):  
Oral Cavity ◽  
Head And Neck ◽  
Viral Infections ◽  
Head And Neck Cancers ◽  
Sinonasal Tract ◽  
Cancer Development ◽  
Oncogenic Viruses ◽  
The World

Head and neck cancers arise in the mucosa lining the oral cavity, oropharynx, hypopharynx, larynx, sinonasal tract, and nasopharynx. The etiology of head and neck cancers is complex and involves many factors, including the presence of oncogenic viruses. These types of cancers are among the most common cancers in the world. Thorough knowledge of the pathogenesis of viral infections is needed to fully understand their impact on cancer development.

Primary Malignant Neoplasms Associated with Chronic Lymphocytic Leukemia

1980 ◽  
Vol 66 (4) ◽  
pp. 431-438 ◽  
Author(s):  
Armando Santoro ◽  
Franco Rilke ◽  
Franca Franchi ◽  
Silvio Monfardini
Keyword(s):  
Chronic Lymphocytic Leukemia ◽  
Alkylating Agents ◽  
Malignant Lesion ◽  
Lymphocytic Leukemia ◽  
Second Primary ◽  
Malignant Neoplasms ◽  
Primary Malignancy ◽  
Second Primary Neoplasms ◽  
Primary Neoplasms ◽  
Cellular And Humoral Immunity

Over the past 2 decades there has been an almost exponential increase in the frequency with which cases of leukemia associated with another primary malignant lesion have been reported. In this study we reported the occurrence of a second primary neoplasm in 82 consecutive cases of chronic lymphocytic leukemia (CLL) admitted to the Istituto Nazionale Tumori of Milan from September 1962 to December 1978. In 16 of these (19.5%), an associated neoplasm was diagnosed subsequently (8 cases) or concurrently (8 cases) to CLL. Head and neck carcinomas and breast cancer had the highest incidence (5 and 3 cases, respectively). The results of this study further support the hypothesis that patients with CLL are prone to develop subsequent cancer. The defective cellular and humoral immunity in CLL may have an etiological role in the development of an additional primary malignancy. Although alkylating agents are known carcinogens in experimental animals and man, our results support the lack of a correlation between treatment with alkylating agents and incidence of second primary neoplasms, as demonstrated by Greene et al. (10).

Second Primary Neoplasms Following a Diagnosis of Breast Cancer

2016 ◽  
pp. 213-234
Author(s):  
Felicity Paterson ◽  
Susannah Stanway ◽  
Lone Gothard ◽  
Navita Somaiah
Keyword(s):  
Breast Cancer ◽  
Second Primary ◽  
Second Primary Neoplasms ◽  
Primary Neoplasms

scholarly journals Use Of Biomarker Testing In Head And Neck Cancers In The United States And EU5

2018 ◽  
Vol 21 ◽  
pp. S40
Author(s):  
JM Noone ◽  
B Shah-Manek ◽  
C Karki ◽  
SM Whitmire ◽  
LA Clark ◽  
...  
Keyword(s):  
United States ◽  
Head And Neck ◽  
The United States ◽  
Head And Neck Cancers ◽  
Biomarker Testing

CT and MRI Features of Recurrent Tumors and Second Primary Neoplasms in Pediatric Patients with Retinoblastoma

2003 ◽  
Vol 181 (3) ◽  
pp. 879-884 ◽  
Author(s):  
Ukihide Tateishi ◽  
Tadashi Hasegawa ◽  
Kunihisa Miyakawa ◽  
Minako Sumi ◽  
Noriyuki Moriyama
Keyword(s):  
Pediatric Patients ◽  
Second Primary ◽  
Second Primary Neoplasms ◽  
Recurrent Tumors ◽  
Mri Features ◽  
Primary Neoplasms ◽  
Ct And Mri

Analysis of Contact Mechanics and Smoothed Particle Hydrodynamic Simulations of Viscoelastic Polymer Sine Waves

2015 ◽  
Author(s):  
Nick Cramer ◽  
Janet Chao ◽  
Travis Tollefson ◽  
M. Teodorescu
Keyword(s):  
United States ◽  
Head And Neck ◽  
Contact Mechanics ◽  
The United States ◽  
Head And Neck Cancers ◽  
Malignant Neoplasms ◽  
Invasive Procedures ◽  
Hydrodynamic Simulations ◽  
Smoothed Particle ◽  
Smoothed Particle Hydrodynamic

According the American Cancer Society’s data, in 2013, an estimated 53,640 people developed head and neck cancers [1], which accounts for about 3% to 5% of all cancers in the United States. Removing head and neck malignant neoplasms is one of the first stages towards patient recovery. However, these types of invasive procedures often lead to disfiguring scars and resections with functional and aesthetical drawbacks (see Figure 1).

Sign in / Sign up

Export Citation Format

Share Document