Study of Mechanism of Ionization Assisted by Methylation in Direct Analysis in Real Time Ion Source

2012 ◽  
Vol 70 (15) ◽  
pp. 1650 ◽  
Author(s):  
Qing Yu ◽  
Binbin Yu ◽  
Hao Yue ◽  
Lili Jiao ◽  
Shuying Liu
Keyword(s):  
Real Time ◽  
Direct Analysis ◽  
Ion Source

scholarly journals Direct Analysis in Real Time by Mass Spectrometric Technique for Determining the Variation in Metabolite Profiles ofCinnamomum tamalaNees and Eberm Genotypes

2012 ◽  
Vol 2012 ◽  
pp. 1-6 ◽  
Author(s):  
Vineeta Singh ◽  
Atul Kumar Gupta ◽  
S. P. Singh ◽  
Anil Kumar
Keyword(s):  
Real Time ◽  
Principal Component ◽  
Direct Analysis ◽  
Ion Source ◽  
Diabetic Patients ◽  
Phytochemical Analysis ◽  
Active Components ◽  
Cinnamomum Tamala ◽  
Wide Range ◽  
Metabolite Profiles

Cinnamomum tamalaNees & Eberm. is an important traditional medicinal plant, mentioned in various ancient literatures such as Ayurveda. Several of its medicinal properties have recently been proved. To characterize diversity in terms of metabolite profiles ofCinnamomum tamalaNees and Eberm genotypes, a newly emerging mass spectral ionization technique direct time in real time (DART) is very helpful. The DART ion source has been used to analyze an extremely wide range of phytochemicals present in leaves ofCinnamomum tamala. Ten genotypes were assessed for the presence of different phytochemicals. Phytochemical analysis showed the presence of mainly terpenes and phenols. These constituents vary in the different genotypes ofCinnamomum tamala. Principal component analysis has also been employed to analyze the DART data of theseCinnamomumgenotypes. The result shows that the genotype ofCinnamomum tamalacould be differentiated using DART MS data. The active components present inCinnamomum tamalamay be contributing significantly to high amount of antioxidant property of leaves and, in turn, conditional effects for diabetic patients.

scholarly journals Easily fabricated ion source for characterizing mixtures of organic compounds by direct analysis in real time mass spectrometry

2017 ◽  
Vol 9 (34) ◽  
pp. 5065-5074 ◽  
Author(s):  
Kathleen T. Upton ◽  
Katherine A. Schilling ◽  
J. L. Beauchamp
Keyword(s):  
Mass Spectrometry ◽  
Real Time ◽  
Organic Compounds ◽  
Direct Analysis ◽  
Ion Source ◽  
Ambient Mass Spectrometry ◽  
Assembly Cost

The EZ-DART ion source for ambient mass spectrometry, with simplified construction, minimal assembly cost, and versatile sampling capabilities, is described.

scholarly journals Coupling of planar chromatography with Direct Analysis in Real Time mass spectrometry

2012 ◽  
Vol 10 (3) ◽  
pp. 703-710 ◽  
Author(s):  
Gertrud Morlock ◽  
Elena Chernetsova
Keyword(s):  
Mass Spectrometry ◽  
Real Time ◽  
Gas Flow ◽  
Direct Analysis ◽  
Ion Source ◽  
Ionization Mass ◽  
Planar Chromatography ◽  
Ionization Source ◽  
Desorption Ionization ◽  
Developing Area

AbstractDirect Analysis in Real Time mass spectrometry (DART-MS) is an emerging and rapidly developing area of ambient desorption ionization mass spectrometric techniques. Its coupling with planar chromatography is especially promising, as compared to other ambient desorption ionization techniques, because it does not require the use of liquids that may distort the shape of a spot by diffusion effects. In the first publications on TLC/HPTLC-DART-MS, due to the fixed, horizontally aligned supply of the gas flow from the DART ionization source to the MS inlet, the introduction of HPTLC/TLC plates as cut strips was inconvenient for quantitation, and the repeatability was very low due to the manual positioning. Recently a new version of the DART ion source was suggested, which allows adjusting the angle of the DART gas stream and the use of a motorized rail, thereby, improving highly the capabilities of TLC/HPTLC-DART-MS. This comprehensive review describes the development and analytical capabilities of TLC/HPTLC-DART-MS, and the general DART-MS perspectives for surface analysis or imaging MS.

scholarly journals Identification of Glycyrrhiza Species by Direct Analysis in Real Time Mass Spectrometry

2010 ◽  
Vol 5 (11) ◽  
pp. 1934578X1000501 ◽  
Author(s):  
Eriko Fukuda ◽  
Masaki Baba ◽  
Noriaki Iwasaki ◽  
Yoshihiro Uesawa ◽  
Kazunori Arifuku ◽  
...  
Keyword(s):  
Real Time ◽  
Ambient Pressure ◽  
Direct Analysis ◽  
Ion Source ◽  
Mass Spectrometric ◽  
The Other ◽  
Glycyrrhiza Inflata ◽  
Species Specific ◽  
Ion Species ◽  
Ground Potential

DART (Direct Analysis in Real Time)-MS is a novel mass spectrometric ion source, and allows the analysis of most compounds at ambient pressure and ground potential by producing [M+H]+ molecular ion species. Using this method, we examined the compounds characteristic of several kinds of licorices. For the analysis of Glycyrrhiza inflata Batalin, the peak at m/z 339 originates mainly from [M+H]+ of licochalcone A (LA), a species-specific compound. This peak was hardly detected in G. glabra Linné and G. uralensis Fischer. These results indicate that G. inflata can be differentiated from the other two species by detection of LA peaks using DART-MS analysis.

scholarly journals Direct Analysis in Real Time Mass Spectrometry for the Nondestructive Investigation of Conservation Treatments of Cultural Heritage

2016 ◽  
Vol 2016 ◽  
pp. 1-11 ◽  
Author(s):  
Marcello Manfredi ◽  
Elisa Robotti ◽  
Greg Bearman ◽  
Fenella France ◽  
Elettra Barberis ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Cultural Heritage ◽  
Real Time ◽  
Direct Method ◽  
High Sensitivity ◽  
Direct Analysis ◽  
Dead Sea ◽  
Ion Source ◽  
Conservation Strategies ◽  
Analytical Methodology

Today the long-term conservation of cultural heritage is a big challenge: often the artworks were subjected to unknown interventions, which eventually were found to be harmful. The noninvasive investigation of the conservation treatments to which they were subjected to is a crucial step in order to undertake the best conservation strategies. We describe here the preliminary results on a quick and direct method for the nondestructive identification of the various interventions of parchment by means of direct analysis in real time (DART) ionization and high-resolution time-of-flight mass spectrometry and chemometrics. The method has been developed for the noninvasive analysis of the Dead Sea Scrolls, one of the most important archaeological discoveries of the 20th century. In this study castor oil and glycerol parchment treatments, prepared on new parchment specimens, were investigated in order to evaluate two different types of operations. The method was able to identify both treatments. In order to investigate the effect of the ion source temperature on the mass spectra, the DART-MS analysis was also carried out at several temperatures. Due to the high sensitivity, simplicity, and no sample preparation requirement, the proposed analytical methodology could help conservators in the challenging analysis of unknown treatments in cultural heritage.

Sign in / Sign up

Export Citation Format

Share Document