scholarly journals Malignant Skin Tumor Misdiagnosed as a Benign Skin Lesion

2016 ◽  
Vol 17 (2) ◽  
pp. 86 ◽  
Author(s):  
So-Min Hwang ◽  
Hao-Ching Pan ◽  
Min-Kyu Hwang ◽  
Min-Wook Kim ◽  
Jong-Seo Lee
Keyword(s):  
Skin Lesion ◽  
Skin Tumor ◽  
Malignant Skin

The use of Integra dermal regeneration matrix in the surgical treatment of a recurrent, extensive malignant skin lesion in the temporal region

2013 ◽  
Vol 154 (6) ◽  
pp. 225-227 ◽  
Author(s):  
Csaba Halmy ◽  
Zoltán Nádai ◽  
Krisztián Csőre ◽  
Adrienne Vajda ◽  
Róbert Tamás
Keyword(s):  
Surgical Treatment ◽  
Skin Lesion ◽  
Surgical Management ◽  
Skin Grafting ◽  
Skin Tumor ◽  
Temporal Region ◽  
Aesthetic Result ◽  
Malignant Skin ◽  
Dermal Regeneration Template ◽  
Dermal Regeneration

Authors report on the use of Integra dermal regeneration template after excision of an extended, recurrent skin tumor in the temporal region. The area covered with Integra was 180 cm2. Skin grafting to cover Integra was performed on the 28th day. Both Integra and the skin transplant were taken 100%. Integra dermal regeneration template can provide good functional and aesthetic result in the surgical management of extended skin tumors over the skull. Orv. Hetil., 2013, 154, 225–227.

Current Progresses of Functional Nanomaterials for Imaging Diagnosis and Treatment of Melanoma

2019 ◽  
Vol 19 (27) ◽  
pp. 2494-2506 ◽  
Author(s):  
Congcong Zhu ◽  
Yunjie Zhu ◽  
Huijun Pan ◽  
Zhongjian Chen ◽  
Quangang Zhu
Keyword(s):  
Treatment Options ◽  
Skin Tumor ◽  
Diagnosis And Treatment ◽  
Chemotherapeutic Drugs ◽  
Imaging Diagnosis ◽  
Functional Nanomaterials ◽  
Disease Prognosis ◽  
Unsuccessful Treatment ◽  
Short Period ◽  
Malignant Skin

Melanoma is a malignant skin tumor that results in poor disease prognosis due to unsuccessful treatment options. During the early stages of tumor progression, surgery is the primary approach that assures a good outcome. However, in the presence of metastasis, melanoma hasbecome almost immedicable, since the tumors can not be removed and the disease recurs easily in a short period of time. However, in recent years, the combination of nanomedicine and chemotherapeutic drugs has offered promising solutions to the treatment of late-stage melanoma. Extensive studies have demonstrated that nanomaterials and their advanced applications can improve the efficacy of traditional chemotherapeutic drugs in order to overcome the disadvantages, such as drug resistance, low drug delivery rate and reduced targeting to the tumor tissue. In the present review, we summarized the latest progress in imaging diagnosis and treatment of melanoma using functional nanomaterials, including polymers, liposomes, metal nanoparticles, magnetic nanoparticles and carbon-based nanoparticles. These nanoparticles are reported widely in melanoma chemotherapy, gene therapy, immunotherapy, photodynamic therapy, and hyperthermia.

Comparing the capabilities of transfer learning models to detect skin lesion in humans

2020 ◽  
Vol 234 (10) ◽  
pp. 1083-1093 ◽  
Author(s):  
Aditi Singhal ◽  
Ramesht Shukla ◽  
Pavan Kumar Kankar ◽  
Saurabh Dubey ◽  
Sukhjeet Singh ◽  
...  
Keyword(s):  
Skin Lesion ◽  
Transfer Learning ◽  
Wiener Filter ◽  
Skin Lesions ◽  
Automated Classification ◽  
Convolutional Networks ◽  
Image Quantization ◽  
Malignant Skin ◽  
Effective Diagnosis

Effective diagnosis of skin tumours mainly relies on the analysis of the characteristics of the lesion. Automatic detection of malignant skin lesion has become a mandatory task to reduce the risk of human deaths and increase their survival. This article proposes a study of skin lesion classification using transfer learning approach. The transfer learning model uses four different state-of-the-art architectures, namely Inception v3, Residual Networks (ResNet 50), Dense Convolutional Networks (DenseNet 201) and Inception Residual Networks (Inception ResNet v2). These models are trained under the dataset comprising seven different classes of skin lesions. The skin lesion images are pre-processed using image quantization, grayscaling and the Wiener filter before final training step. These models are compared for performance evaluation on different metrics. The present study shows the efficacy of the methodology for automated classification of lesion images.

Giant Basal Cell Carcinoma of the Forehead with Extensive Intracranial Involvement

2007 ◽  
Vol 116 (9) ◽  
pp. 663-666 ◽  
Author(s):  
Ilka Charlotte Naumann ◽  
Susan R. Cordes
Keyword(s):  
Skin Lesion ◽  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Basal Cell ◽  
Growth Pattern ◽  
Cancer Surveillance ◽  
Review Of The Literature ◽  
Intracranial Involvement ◽  
Malignant Skin ◽  
Giant Basal Cell Carcinoma

Basal cell carcinoma (BCC) is the most common malignant skin lesion and is frequently curatively treated with local excision. Improper removal or neglect of BCC is a particular problem for head and neck surgeons. We describe a case of a recurrent BCC that aggressively grew from the forehead skin through the skull and into the frontal lobe. We also present a review of the literature. Despite its fairly benign growth pattern, BCC should never be underestimated, and care should be taken not only in the complete primary excision but also in cancer surveillance.

Atypical Fibroxanthoma

2016 ◽  
Vol 140 (4) ◽  
pp. 376-379 ◽  
Author(s):  
Liurka López ◽  
Román Vélez
Keyword(s):  
Standard Of Care ◽  
Skin Tumor ◽  
Surgical Removal ◽  
Genetic Studies ◽  
Undifferentiated Pleomorphic Sarcoma ◽  
Atypical Fibroxanthoma ◽  
Pleomorphic Sarcoma ◽  
Malignant Skin ◽  
Abundant Cytoplasm ◽  
The Difference

Atypical fibroxanthoma is a malignant skin tumor with histologic features similar to those of undifferentiated pleomorphic sarcoma, but lacking its more aggressive behavior. The tumor is composed of pleomorphic cells with hyperchromatic nuclei and abundant cytoplasm, commonly arranged in a spindle cell pattern. Recent genetic studies have identified similarities between atypical fibroxanthoma and undifferentiated pleomorphic sarcoma, such as the presence of 9p and 13q deletions in both tumors, favoring a common histogenesis. However, the lack of K-ras and H-ras mutations in atypical fibroxanthoma compared with undifferentiated pleomorphic sarcoma could explain the difference in aggressiveness and continued separation of these entities. Exclusion of other neoplasms by histology and immunohistochemistry followed by complete surgical removal remains the standard of care.

Patients Spend More Time With the Physician for Excision of a Malignant Skin Lesion Than for Excision of a Benign Skin Lesion

2004 ◽  
Vol 30 (3) ◽  
pp. 351-354
Author(s):  
Steven R. Feldman ◽  
Fabian Camacho ◽  
Phillip M. Williford ◽  
Daniel M. Siegel ◽  
Rajesh Balkrishnan ◽  
...  
Keyword(s):  
Skin Lesion ◽  
Malignant Skin

scholarly journals Premalignant and malignant skin lesion following photochemotherapy

Skin Cancer ◽  
2003 ◽  
Vol 18 (2) ◽  
pp. 148-156
Author(s):  
Taiki ISEI ◽  
Takeshi HORIO
Keyword(s):  
Skin Lesion ◽  
Malignant Skin

scholarly journals Two cases of the systemic albinism which produced the malignant skin tumor.

Skin Cancer ◽  
1991 ◽  
Vol 6 (1) ◽  
pp. 90-94 ◽  
Author(s):  
Yoh NAGAO ◽  
Kenzo ARAKAWA ◽  
Jiro ARATA
Keyword(s):  
Skin Tumor ◽  
Malignant Skin

scholarly journals Expression of chemokine receptors in angiosarcoma

2017 ◽  
Vol 2 (2) ◽  
Author(s):  
Tomoo Kishi ◽  
Yuki Yamamoto ◽  
Chikako Kaminaka ◽  
Seiko Toyozawa ◽  
Hiroshi Matsunaka ◽  
...  
Keyword(s):  
Chemokine Receptors ◽  
Histological Type ◽  
Receptor Expression ◽  
Skin Tumor ◽  
Patient Age ◽  
Sex Development ◽  
Patient Âgé ◽  
Significant Difference ◽  
Development Site ◽  
Malignant Skin

<p>Angiosarcoma is a rapidly progressing malignant skin tumor associated with a poor prognosis. We report an immunohistochemical investigation of chemokine receptors in angiosarcoma. The aim is to investigate chemokine receptor expression and, if it is expressed, to histologically discuss its association with age, sex, development site, and histological type. Analyzed were 12 angiosarcoma samples (mean patient age: 75.7 years old) collected by biopsy or surgery from patients at our department by comparing with 4 granuloma telangiectaticum samples (mean patient age: 37.5 years old) and 16 healthy skin samples as controls. CXCR4, CCR6, CCR7, and SDF-1 expressions were immunohistochemically investigated. CXCR4 expression was positive in 6 of the 12 samples. CCR6 and CCR7 were negative in all samples. SDF-1 was positive in 4 samples. Out of the 6 CXCR4-positive samples, 4 were SDF-1-positive. No significant difference associated with age, sex, development site, or histological type was noted in the expression of CXCR4, CCR6, CCR7, or SDF-1. Although CXCR4 is regarded as an index of tumor aggressiveness of malignant melanoma, it is suggested that chemokine receptors, such as CXCR4, do not serve as useful markers of angiosarcoma.</p>

scholarly journals Skin Lesion Segmentation using Deep Hypercolumn Descriptors

2017 ◽  
Vol 3 (1) ◽  
Author(s):  
Dhanesh Ramachandram ◽  
Graham W. Taylor
Keyword(s):  
Image Segmentation ◽  
Skin Lesion ◽  
State Of The Art ◽  
Jaccard Index ◽  
Segmentation Method ◽  
Lesion Segmentation ◽  
Malignant Skin

We present a image segmentation method based on deep hypercolumndescriptors which produces state-of-the-art results for thesegmentation of several classes of benign and malignant skin lesions.We achieve a Jaccard index of 0.792 on the 2017 ISIC SkinLesion Segmentation Challenge dataset.

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