scholarly journals Red Meat Intake and Risk of Non-Hodgkin Lymphoma: A Meta-Analysis

2015 ◽  
Vol 15 (23) ◽  
pp. 10421-10425 ◽  
Author(s):  
Hosein Fallahzadeh ◽  
Maria Cheraghi ◽  
Neda Amoori ◽  
Mehrangiz Alaf
Keyword(s):  
Hodgkin Lymphoma ◽  
Meta Analysis ◽  
Red Meat ◽  
Meat Intake ◽  
Non Hodgkin Lymphoma ◽  
Red Meat Intake

scholarly journals Red Meat Intake and Risk of Rheumatoid Arthritis: A Categorical and Dose-Response Meta-Analysis

2021 ◽  
Author(s):  
WeiWei Chen ◽  
Ke Liu ◽  
Qing Su ◽  
Xinxian Sang ◽  
Yihan Hu ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Dose Response ◽  
Observational Studies ◽  
Meta Analysis ◽  
Red Meat ◽  
High Dose ◽  
Case Control Studies ◽  
Meat Intake ◽  
Red Meat Intake ◽  
The Impact

Abstract Objective: Findings from previous observational studies on the association between red meat intake and risk of rheumatoid arthritis (RA) are inconsistent. Therefore, we aimed to evaluate the impact of red meat intake on the incidence of RA by meta-analysis.Methods: PubMed and Web of Science were searched for eligible observational studies regarding the association between red meat intake and the risk of RA until June 30, 2021. Risk estimates with corresponding 95% confidence interval (95% CI) were pooled. Subgroup analysis and meta-regression analysis were performed to explore the potential sources of heterogeneity. Sensitivity analysis and publication bias test were also carried out.Results: A total of eleven studies were selected, involving 4 cohort studies with 5 203 identified cases from 349 776 individuals and 7 case-control studies with 3 762 cases and 6 856 controls. The pooled risk estimate of RA risk was 0.94 (95% CI: 0.77 to 1.15) for ever versus non/occasional red meat intake, while high dose of red meat intake increased the risk of RA (OR: 1.26, 95% CI: 1.07 to 1.50) in the categorical meta-analysis. Dose-response meta-analysis suggested a non-linear dose-response relationship between red meat intake and RA (P=0.028). Red meat intake was found to be a risk factor of RA when the dose ranged from 96 to 166 g/day.Conclusion: High dose of red meat intake could increase the risk of RA. Mechanistic studies are warranted to clarify the aetiologic pathways through which high dose of red meat intake may promote RA.

Meat intake and non-Hodgkin lymphoma: a meta-analysis of observational studies

2016 ◽  
Vol 27 (5) ◽  
pp. 595-606 ◽  
Author(s):  
Angelo G. Solimini ◽  
Anna Maria Lombardi ◽  
Caterina Palazzo ◽  
Maria De Giusti
Keyword(s):  
Hodgkin Lymphoma ◽  
Observational Studies ◽  
Meta Analysis ◽  
Meat Intake ◽  
Non Hodgkin Lymphoma

scholarly journals Red Meat Intake and Glycemic and Insulinemic Risk Factors for Type 2 Diabetes: A Systematic Review and Meta-Analysis

2021 ◽  
Vol 5 (Supplement_2) ◽  
pp. 522-522
Author(s):  
Lisa Sanders ◽  
Meredith Wilcox ◽  
Kevin Maki
Keyword(s):  
Risk Factors ◽  
Systematic Review ◽  
Glucose Tolerance ◽  
Fasting Glucose ◽  
Meta Analysis ◽  
Postprandial Glucose ◽  
Red Meat ◽  
Meat Intake ◽  
Red Meat Intake

Abstract Objectives Results from observational studies have suggested an association of red meat intake with increased risk of type 2 diabetes (T2D).  However, results from randomized controlled trials (RCTs) have not shown clear evidence to support a mechanistic link between red meat intake and T2D risk factors.  The objective of this systematic review and meta-analysis was to evaluate the impact of red meat intake on markers of glucose tolerance, including fasting glucose and insulin, postprandial glucose and insulin, insulin sensitivity and glycated hemoglobin (HbA1c). Methods A systematic review and meta-analysis was conducted on RCTs evaluating the effect of red meat intake, compared to lower or no red meat intake, on markers of glucose tolerance in adults.  A search of PubMed yielded 17 relevant RCTs.  Pooled estimates were expressed as standardized mean differences (SMD) between the red meat intervention and the control intervention with less or no red meat. Results Compared to diets with little or no red meat intake, there was no significant impact of red meat intake on insulin sensitivity (SMD: −0.12; 95% CI: −0.43, 0.19), insulin resistance (SMD: 0.23; 95% CI: −0.22, 0.68), fasting glucose (SMD: 0.12; 95% CI: −0.06, 0.30), fasting insulin (SMD: 0.16; 95% CI: −0.10, 0.42) or HbA1c (SMD: 0.00; 95% CI: −0.42, 0.43).  Red meat intake modestly, but significantly, reduced postprandial glucose (SMD: −0.46; 95% CI: −0.77, −0.16; P < 0.003) compared to diets with little or no red meat intake in a small number of studies (n = 3).  However, there was no effect on postprandial insulin (SMD: −0.74; 95% CI: −1.64, 0.16). Conclusions The results of this meta-analysis suggest red meat intake does not impact several glycemic and insulinemic risk factors for T2D.  Thus, it is unclear whether there is a causal relationship with red meat intake and T2D risk or if other confounding lifestyle factors may be driving the observed association.  Further investigations are needed, particularly on other markers of glucose tolerance, such as pancreatic beta-cell function, to better understand whether a causal relationship exists between red meat intake and risk of T2D.  PROSPERO Registration:   CRD42020176059 Funding Sources This research was funded by Beef Checkoff.

Food of animal origin and risk of non-Hodgkin lymphoma and multiple myeloma: A review of the literature and meta-analysis

2016 ◽  
Vol 100 ◽  
pp. 16-24 ◽  
Author(s):  
Saverio Caini ◽  
Giovanna Masala ◽  
Patrizia Gnagnarella ◽  
Ilaria Ermini ◽  
William Russell-Edu ◽  
...  
Keyword(s):  
Multiple Myeloma ◽  
Hodgkin Lymphoma ◽  
Meta Analysis ◽  
Animal Origin ◽  
Review Of The Literature ◽  
Non Hodgkin Lymphoma ◽  
Food Of Animal Origin

Thrombotic complications in adult patients with lymphoma: a meta-analysis of 29 independent cohorts including 18 018 patients and 1149 events

Blood ◽  
2010 ◽  
Vol 115 (26) ◽  
pp. 5322-5328 ◽  
Author(s):  
Vanesa Caruso ◽  
Augusto Di Castelnuovo ◽  
Susana Meschengieser ◽  
Maria A. Lazzari ◽  
Giovanni de Gaetano ◽  
...  
Keyword(s):  
Hodgkin Lymphoma ◽  
Meta Analysis ◽  
Hematologic Malignancies ◽  
Incidence Rates ◽  
Clinical Implications ◽  
Low Grade ◽  
Thrombotic Risk ◽  
Non Hodgkin Lymphoma ◽  
Thrombotic Complications ◽  
Exact Maximum Likelihood

AbstractThrombotic complications in hematologic malignancies have important clinical implications. In this meta-analysis we sought to obtain accurate estimates of the thrombotic risk in lymphoma patients. Articles were searched in electronic databases and references. Eighteen articles were identified (29 cohorts, 18 018 patients and 1149 events). Pooled incidence rates (IRs) were calculated by the use of a method based on the exact maximum likelihood binomial distribution. The global IR of thrombosis was 6.4% (95% confidence interval [CI] 6.0%-6.8%). The global IRs of venous or arterial events were 5.3% (95% CI, 5.0%-5.7%) and 1.1% (95% CI, 0.9%-1.2%), respectively. The IR of thrombosis observed in subjects with non-Hodgkin lymphoma (NHL) was 6.5% (95% CI, 6.1%-6.9%), significantly greater than that observed for patients with Hodgkin lymphoma (4.7%; 95% CI, 3.9%-5.6%). Within NHL, patients with high-grade disease had a greater risk of events (IR 8.3%; 95% CI, 7.0%-9.9%) than low-grade disease (IR 6.3%; 95% CI, 4.5%-8.9%). This meta-analysis shows that the IR of thrombosis in lymphoma patients is quite high, especially in those with NHL at an advanced stage of the disease. These results may help better defining lymphoma populations at high thrombotic risk, to whom prophylactic approaches could be preferentially applied.

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