scholarly journals Middle latency auditory evoked potential in child population

2016 ◽  
Vol 26 (3) ◽  
pp. 368 ◽  
Author(s):  
Anna Caroline Silva de Oliveira ◽  
Simone Fiuza Regaçone ◽  
Ana Claudia Figueiredo Frizzo

Introduction: The middle-latency auditory evoked potential is used to evaluate any abnormality that might impair the central auditory pathways, which are situated between the brain stem and the primary auditory cortex. Objective: To analyse the middle-latency auditory evoked potentials in children. Methods: This is a descriptive and cross-sectional study. Pure-tone audiometry was performed, and if no change was detected, Biologic’s portable Evoked Potential System (EP) was used to measure auditory evoked potentials. The identification of the responses was performed using electrodes positioned at C3 and C4 (left and right hemispheres) in reference to ears A1 and A2 (left and right earlobe). These were ipsilaterally and contralaterally paired and landed at Fpz (forehead), in two steps, with alternating stimulation of the right and left ears. Results: In this study, there was 100% detectability of the Na, Pa, and Nb components and interamplitude Na–Pa. This study compared different electrode leads, and there was no significant difference between the different electrode positions studied for the right and left ears in the studied population. Conclusion: It was concluded that the examination of middle-latency evoked potential is steady and feasible for the studied age group regardless of electrode position.

Author(s):  
PhD M.D, Seidel Guerra López ◽  
M.D, María de Los A. Pedroso Rodríguez ◽  
M.D, Diego Cantero ◽  
Gilvan Aguiar da Silva

Objective: Clinical application of middle-latency auditory evoked potential (MLAEPs) has been increasing, highlighting the importance of understanding the nature of P50, a component of middle-latency auditory evoked potential. We manipulated stimulus frequency bands in auditory stimuli in order to investigate the nature of P50 in human auditory evoked potentials. Methods: Two paradigms have been used to obtain P50: one is a conditioning /testing paradigm in which paired of pure tone (1000Hz) are delivered, and the other was presented paired of clicks, both with an intensity of 60 dB sound pressure level above the auditory threshold. A total of 30 healthy volunteers were recruited for this study among Center of genetic engineering (fifteen man and fifteen women, mean age of 36, 5). All without consumption of caffeine, cigarettes and drugs. Results: No statistically significant differences occurred between the P50 amplitudes and latencies for the pure tone and those for the clicks. Conclusions: Our present results indicate that P50 in humans may reflect a feed-forward mechanism of the brain where a preceding stimulus drives sensory gating mechanisms in preparation for a second stimulus, but the contained frequency doesn't influence on the P50. Both types (tones or clicks) can be used in the exploration of patient with this evoked potential.


1985 ◽  
Vol 43 (4) ◽  
pp. 347-354 ◽  
Author(s):  
C. Collin ◽  
F. Lolas

Starting off from the notion that the cerebral hemispheres differ in their processing mode, this paper reports on stimulus intensity modulation of auditory evoked potentials recorded from hemispheric leads (C3 and C4 referenced to ipsilateral mastoid processes) in a sample of 40 male Ss between 18 to 40 years of age. The experimental set up involved the recording of series of 100 trials to binaural clicks of 63.5, 74.6 and 85dB AL. Ss who were augmenters at the vertex showed positive Amplitude-Intensity function slopes over the left hemisphere; when Ss were Reducers at the vertex, the slopes were negative on the right hemisphere. These results are interpreted in terms of attention deployment or allocation to one or the other hemispheric processing mode. This might constitute a trait-like enduring subject characteristic whose relation to traditional psychometric variables needs further exploration. The modality especificity of this phenomenon is also discussed.


CoDAS ◽  
2013 ◽  
Vol 25 (5) ◽  
pp. 407-412 ◽  
Author(s):  
Renata Parente de Almeida ◽  
Carla Gentile Matas

PURPOSE: To characterize the findings obtained in the long latency auditory evoked potentials in malnourished children, as well as to compare them to the results obtained for children at the same age who present typical development. METHODS: Sixty-five children aged between 7 and 12 years old, of both genders, were evaluated. The control group consisted of 34 children with normal development and the study group consisted of 31 children diagnosed with malnutrition. All children underwent conventional pure tone audiometry, acoustic impedance measurement, dichotic digit test and long latency auditory evoked potentials. RESULTS: The study group presented a statistically significant difference for latencies of the components P1, N1 and P300. The latencies of these components were higher than those of the control group. Concerning the types of alterations found in the study group, increased latency for P1 and P300 and the absence of response in N1 were predominant. The control group showed a statistically significant difference in the amplitude of P300 when compared to the right and left ears. CONCLUSION: Malnourished children present with changes in the long latency auditory evoked potentials, suggesting a deficit in central auditory pathways and alterations in the processing of acoustic information.


2017 ◽  
Vol 22 (04) ◽  
pp. 460-468 ◽  
Author(s):  
Luísa Gabriel ◽  
Luíza Vernier ◽  
Maria Ferreira ◽  
Adriana Silveira ◽  
Márcia Machado

Introduction Studies using the Brainstem Auditory Evoked Potential with speech stimulus are increasing in Brazil, and there are divergences between the methodologies used for testing. Objectives To analyze the parameters used in the study of the Brainstem Auditory Evoked Potentials with speech stimulus. Data Synthesis The survey was performed using electronic databases. The search strategy was as follows: “Evoked potentials, auditory” OR “Brain stem” OR “Evoked potentials, auditory, brain stem” AND “Speech.” The survey was performed from June to July of 2016. The criteria used for including articles in this study were: being written in Portuguese, English or Spanish; presenting the description of the testing parameters and the description of the sample. In the databases selected, 2,384 articles were found, and 43 articles met all of the inclusion criteria. The predominance of the following parameters was observed to achieve the potential during study: stimulation with the syllable /da/; monaural presentation with greater use of the right ear; intensity of 80 dB SPL; vertical placement of electrodes; use of in-ear headphones; patient seated, distracted in awake state; alternating polarity; use of speech synthesizer software for the elaboration of stimuli; presentation rate of 10.9/s; and sampling rate of 20 kHz. Conclusions The theme addressed in this systematic review is relatively recent. However, the results are significant enough to encourage the use of the procedure in clinical practice and advise clinicians about the most used procedures in each parameter.


2017 ◽  
Vol 21 (04) ◽  
pp. 351-357
Author(s):  
Kelly Vasconcelos Martins ◽  
Daniela Gil

Introduction The registry of the component P1 of the cortical auditory evoked potential has been widely used to analyze the behavior of auditory pathways in response to cochlear implant stimulation. Objective To determine the influence of aural rehabilitation in the parameters of latency and amplitude of the P1 cortical auditory evoked potential component elicited by simple auditory stimuli (tone burst) and complex stimuli (speech) in children with cochlear implants. Method The study included six individuals of both genders aged 5 to 10 years old who have been cochlear implant users for at least 12 months, and who attended auditory rehabilitation with an aural rehabilitation therapy approach. Participants were submitted to research of the cortical auditory evoked potential at the beginning of the study and after 3 months of aural rehabilitation. To elicit the responses, simple stimuli (tone burst) and complex stimuli (speech) were used and presented in free field at 70 dB HL. The results were statistically analyzed, and both evaluations were compared. Results There was no significant difference between the type of eliciting stimulus of the cortical auditory evoked potential for the latency and the amplitude of P1. There was a statistically significant difference in the P1 latency between the evaluations for both stimuli, with reduction of the latency in the second evaluation after 3 months of auditory rehabilitation. There was no statistically significant difference regarding the amplitude of P1 under the two types of stimuli or in the two evaluations. Conclusion A decrease in latency of the P1 component elicited by both simple and complex stimuli was observed within a three-month interval in children with cochlear implant undergoing aural rehabilitation.


2017 ◽  
Vol 19 (3) ◽  
pp. 165
Author(s):  
Audrei Thayse Viegel de Ávila ◽  
Pricila Sleifer ◽  
Vanessa Onzi Rocha ◽  
Rafael Fabiano Machado Rosa ◽  
Paulo Ricardo Gazzola Zen

A realização dos Potencias Evocados Auditivos de Longa Latência - PEALL em indivíduos com síndrome de Down - SD podem fornecer dados importantes sobre o processamento cerebral da audição e suas associações necessária para um bom desenvolvimento da linguagem. Analisar latências e amplitudes obtidas no registro dos componentes exógenos e endógeno dos PEALL, em adolescentes com SD, assim como correlacionar os achados entre os gêneros. Foram incluídos no estudo onze adolescentes com SD, que não apresentassem perdas auditivas, sete do gênero feminino e quatro do masculino, com idade mínima de 13 e máxima de 17 anos. Foi realizada avaliação auditiva periférica básica e pesquisa dos PEALL, incluindo o potencial cognitivo (P3). As médias encontradas para as latências dos componentes exógenos P1, N1, P2, N2 foram, respectivamente, de 110,2ms; 180,3ms; 322,2ms e 492,5ms para orelha direita e 100,2ms; 168,3ms; 323,1ms e 497,5ms para orelha esquerda. As amplitudes médias encontradas para P1N1 e N1P2 foram, respectivamente, 15,0μV e 16,0μV para orelha direita e 16,8μV e 18,7μV para orelha esquerda. A média encontrada para a latência da onda P3 foi 651,7ms e amplitude média foi 10,0μV. Houve diferença significativa entre gêneros para a latência de N1 na orelha direita (p=0,020). Na análise das ondas P1, N1, P2, N2 e P3 foi possível observar aumento das latências e amplitudes dentro dos padrões de normalidade. Foi verificada correlação significativa entre gêneros somente para as latências de N1 na orelha direita, tendo o gênero feminino latências superiores. Sugere-se a realização de estudos, que usem os procedimentos de PEALL para avaliar e monitorar, objetivamente, as intervenções e evoluções terapêuticas na SD.Palavra-chave: Audição. Eletrofisiologia. Potenciais Evocados Auditivos.AbstractThe accomplishment of Late Latency Auditory Evoked Potential - LLAEP in individuals with Down syndrome - DS can provide important data from brain processing of hearing and their associations necessary for a good language development. To evaluate latencies and amplitudes obtained from exogenous and endogenous components of LLAEP in teenagers with DS and correlate the findings between genders. This study included 11 teenagers with DS and without hearing loss, seven females and four males with minimum age 13 and maximum 17 years. Hearing evaluation and research of the LLAEP were performed, including cognitive potential (P3). The averages found for the latencies of exogenous components P1, N1, P2, N2 were respectively 110,2ms; 180,3ms; 322,2ms and 492,5ms to right ear and 100,2ms; 168,3ms; 323,1ms and 497,5ms to left ear. The averages found for the amplitudes P1N1 and N1P2 were respectively 15.00μV and 16.0 μV to right ear and 16.8μV and 18.7μV to left ear. The mean found for the latency of the P3 wave was 651.7 ms and mean amplitude 10.0μV. There was a significant difference between genders for N1 latency in the right ear (p=0.020). Analyzing P1, N1, P2, N2 and P3 waves, it was observed increased latencies and amplitudes within the normal range. Significant correlation was observed between genders only for N1 latencies for the right ear, females had higher latencies. It is suggested to carry out studies that use the LLAEP procedures to evaluate and objectively monitor the interventions and therapeutics evolutions in DS.Keywords: Hearing. Electrophysiology. Evoked Potentials, Auditory.


2005 ◽  
Vol 103 (5) ◽  
pp. 944-950 ◽  
Author(s):  
Bertram Scheller ◽  
Gerhard Schneider ◽  
Michael Daunderer ◽  
Eberhard F. Kochs ◽  
Bernhard Zwissler

Background The dose-dependent suppression of midlatency auditory evoked potentials by general anesthetics has been proposed to measure depth of anesthesia. In this study, perioperatively recorded midlatency auditory evoked potentials were analyzed in a time-frequency space to identify significant changes induced by general anesthesia. Methods Perioperatively recorded auditory evoked potentials of 19 patients, recorded at varying levels of anesthesia, were submitted to a multiscale analysis using the wavelet analysis. Energy contents of the signal were calculated in frequency bands 0-57.1 Hz, 57.1-114.3 Hz, 114.3-228.6 Hz, and 228.6-457.1 Hz. A Friedman test and a Dunn multiple comparisons test were performed to identify significant differences. Results Statistical evaluation showed a highly significant decrease of the wavelet energies for the frequency bands 57.1-114.3 Hz (P < 0.0001), 114.3-228.6 Hz (P < 0.0001), and 228.6-457.1 Hz (P < 0.0001) for the measuring points representing deep general anesthesia. This decrease is accompanied by a decrease in the wavelet energy of the frequency band 0-57.1 Hz of no statistical significance (P = 0.021) (level of significance set to P = 0.01). The changes are most prominent in the poststimulus interval between 10 and 30 ms. Conclusions This study describes the presence of high-frequency components of the auditory evoked potential. The amount of these components is higher during responsiveness when compared to unconsciousness. Temporal localization of the high-frequency components within the auditory evoked potential shows that they represent a response to the auditory stimulus. Further studies are required to identify the source of these high-frequency components.


2006 ◽  
Vol 64 (3a) ◽  
pp. 619-623 ◽  
Author(s):  
Paulo Sergio A. Henriques Filho ◽  
Riccardo Pratesi

OBJECTIVE: To evaluate the frequency and degree of severity of abnormalities in the auditory pathways in patients with Chiari malformations type I and II. METHOD: This is a series-of-case descriptive study in which the possible presence of auditory pathways abnormalities in 75 patients (48 children and 27 adults) with Chiari malformation types I and II were analyzed by means of auditory evoked potentials evaluation. The analysis was based on the determination of intervals among potentials peak values, absolute latency and amplitude ratio among potentials V and I. RESULTS: Among the 75 patients studied, 27 (36%) disclosed Arnold-Chiari malformations type I and 48 (64%) showed Arnold-Chiari malformations type II. Fifty-three (71%) of these patients showed some degree of auditory evoked potential abnormalities. Tests were normal in the remaining 22 (29%) patients. CONCLUSION: Auditory evoked potentials testing can be considered a valuable instrument for diagnosis and evaluation of brain stem functional abnormalities in patients with Arnold-Chiari malformations type I and II. The determination of the presence and degree of severity of these abnormalities can be contributory to the prevention of further handicaps in these patients either through physical therapy or by means of precocious corrective surgical intervention.


2018 ◽  
Vol 23 (02) ◽  
pp. 142-146 ◽  
Author(s):  
Dulce Azevedo Ferreira ◽  
Claudine Devicari Bueno ◽  
Sady Selaimen de Costa ◽  
Pricila Sleifer

Introduction The Mismatch Negativity (MMN) auditory evoked potential evaluation is a promising procedure to assess objectively the ability of auditory discrimination. Objective To characterize the latency and amplitude values of MMN in children with normal auditory thresholds and without auditory complaints. Methods Children between 5 and 11 years old participated in the present study. All participants underwent acoustic immittance measurements and tonal and vocal audiometry. The MMN was recorded with the MASBE ATC Plus system (Contronic, Pelotas, RS, Brazil). The electrodes were fixed in Fz (active electrode), Fpz (ground electrode) and in M2 and M1 (references electrodes). The intensity used was 80 dBHL, the frequent stimulus was 1,000 Hz and the rare stimulus was 2,000 Hz. The stimuli were presented in both ears separately. Results For the female group, the mean latencies and amplitude of MMN were 177.3 ms and 5.01 μV in the right ear (RE) and 182.4 ms and 5.39 μV in the left ear (LE). In the male group, the mean latencies were 194.4 ms in the RE and 183.6 ms in the LE, with an amplitude of 5.11 μV in the RE and 5.83 μV in the LE. There was no statistically significant difference between ears (p = 0.867 - latency and p = 0.178 - amplitude), age (p > 0.20) and the gender of the participants (p > 0.05). Conclusion Using the described protocol, the mean latency value of MMN was 184.0 ms for RE and 182.9 ms for LE, and the amplitude was 5.05 μV and 5.56 μV for the left and right ears, respective.


2009 ◽  
Vol 20 (07) ◽  
pp. 397-408 ◽  
Author(s):  
Fawen Zhang ◽  
Ravi N. Samy ◽  
Jill M. Anderson ◽  
Lisa Houston

Background: It has been theorized that neural recovery is related to temporal coding of speech sounds. The recovery function of cortically generated auditory evoked potentials has not been investigated in cochlear implant (CI) users. Purpose: This study characterized the recovery function of the late auditory evoked potential (LAEP) using a masker–probe paradigm in postlingually deafened adult CI users and young normal-hearing (NH) listeners. Research Design: A case-control study of the late auditory evoked potentials using electrophysiological technique was performed. The LAEP was evoked by 1 kHz tone bursts presented in pairs, with the first stimuli as the maskers and the second stimuli as the probes. The masker–probe intervals (MPIs) were varied at 0.7, 1, 2, 4, and 8 sec, with an interpair interval of 12 sec. Study Sample: Nine CI users and nine NH listeners participated in this study. Data Collection and Analysis: The normalized amplitude from the probe response relative to the masker response was plotted as a function of the MPI to form a recovery function. The latency shift for the probe response relative to the masker response was calculated. Results: The recovery function was approximately linear in log scale of the MPI in NH listeners, while it showed somewhat different recovery patterns with a large intersubject variability in CI users. Specifically, although the probe response was approximately 60 percent of the masker response for the MPI of 0.7 sec in both groups, the recovery function of CI users displayed a nonlinear pattern, with a steeper slope than that of NH listeners. The probe response completely recovered at the MPI of 4 sec in NH listeners and at the MPI of 2 sec in CI users. N1 and P2 latencies from probe responses were shorter than those from masker responses in NH listeners, while no latency difference was found between probe responses and masker responses in CI users. Conclusions: Our interpretation of these findings is that the faster recovery of the LAEP in CI users is related to abnormal adaptation mechanisms and a less prominent role of the components with longer latencies in the LAEP of CI users. Other mechanisms such as the compromised inhibitory regulation in the auditory system and the aging effect in CI users might also play a role. More research needs to be done to determine whether the slope of the LAEP recovery function is correlated with speech-perception performance.


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