Evaluation of Hyponatremia in Ischemic Stroke Patients in a Tertiary Care Hospital of Karachi, Pakistan

Objectives: To determine the frequency and impact of hyponatermia on outcome in patients of acute ischemic stroke admitted to a Tertiary Care Hospital, Karachi. Study Design: Prospective, cross-sectional, observational study. Setting: Department of Medicine, Abbasi Shaheed Hospital, Karachi. Period: January 2015 to May 2018. Material and Methods: A total of 110 patients of both gender presented with acute ischemic stroke and hyponatermia (2 consecutive serum sodium levels (< 135 mEq/L). Diagnosis of syndrome of inappropriate secretion of antidiuretic hormone (SIADH) and cerebral salt wasting (CSW) was based on predefined criteria. Mortality was considered in terms of modified Rankin Scale with score of 6 within four weeks of admission. Data was analyzed by using SPSS Version 20. Result: Out of 110 acute ischemic stroke patients, 66 (60%) were male and 44 (40%) were female. The mean age was 61.45 ± 11.8 years. Mean serum sodium level was 128.4 ± 6.07. Older ages are associated with high mortality rate of 20%. Moderate (29%) and severe (11%) hyponatremia was associated with 21% and 33% mortality respectively. Overall mortality in patients with hyponatremia was 14.5%. Conclusion: Mortality rates are higher in acute ischemic stroke patients presented with moderate to severe hyponatremia.

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Pattern of Stroke in Diabetic and Non-Diabetic Patients Admitted at a Tertiary Care Hospital, a Cross Sectional Study

Journal of Clinical Case Reports and Studies ◽

10.31579/2690-8808/073 ◽

2021 ◽

Vol 2 (5) ◽

pp. 01-05

Author(s):

Mubashir Ahmed ◽

Sohail Ahmed Siddiqui ◽

Abdul Haq ◽

Atif Ahmed ◽

Pir Abdul Hayee ◽

...

Keyword(s):

Ischemic Stroke ◽

Acute Stroke ◽

Tertiary Care Hospital ◽

Tertiary Care ◽

Haemorrhagic Stroke ◽

Cross Sectional Study ◽

Care Hospital ◽

Sectional Study ◽

Stroke Patients ◽

Cross Sectional

Objective: To determine the frequency of diabetic among stroke patients and to compare the pattern of stroke in diabetic and non-diabetic stroke patients admitted at a tertiary care hospital in Hyderabad, Sindh. Methods: A cross sectional study enrolled 148 consecutive adult acute stroke patients admitted at Liaquat University Hospital, Hyderabad, during Sep 2014 to Feb 2015. Demographic, clinical, radio-imaging and laboratory data were collected on structured questionnaire to identify diabetes, type of stroke and different risk factors of stroke. Data was entered and analysed by using SPSS version 16. Association was seen by using Pearson’s Chi-square test and Independent t test. A P value of < 0.05 was considered statistically significant. Results: A total of 148 acute stroke cases were enrolled in the study. Males were 92 (62%). Mean age of study participants was 51.21 ± 10.19 years. Diabetes was found in 104 (70.3%) stroke patients. Ischemic stroke was seen in 101 (68.2%) and haemorrhagic stroke seen in 47 (31.8) stroke patients. Diabetes was more common in ischemic stroke 81 (80.2) as compared to haemorrhagic stroke 23 (48.9%) (P< 0.05). Hospital mortality of stroke patients was 37 (25%). No difference of mortality in diabetic and non-diabetic (P>0.05) stroke patients was recorded. Conclusion: Diabetes was found in majority of stroke patients. Ischemic stroke was more common than haemorrhagic stroke. Ischaemic stroke is more prevalent in diabetic whereas haemorrhagic stroke was more in non-diabetic stroke patients. Prognosis of stroke was bad in both diabetic and non-diabetic stroke patients.

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Socio-demographic characteristics of ischemic stroke patients in a tertiary care hospital of Nepal

Journal of Brain and Spine Foundation Nepal ◽

10.3126/jbsfn.v1i1.32222 ◽

2020 ◽

Vol 1 (1) ◽

pp. 16-19

Author(s):

Ritesh Luitel ◽

Sujan Dhital ◽

Subodh Sharma Paudel ◽

Suman Bhattarai

Keyword(s):

Diabetes Mellitus ◽

Risk Factors ◽

Ischemic Stroke ◽

Alcohol Consumption ◽

Tertiary Care Hospital ◽

Tertiary Care ◽

Demographic Characteristics ◽

Care Hospital ◽

Stroke Patients ◽

History Of

Introduction: Incidence of stroke patients is increasing in low income countries like Nepal where management of these patients is challenging due to poor healthcare resources. Ischemic stroke is related to risk factors like age, male population, hypertension, diabetes mellitus, smoking and alcohol. Identification of these risk factors in the vulnerable population is important for prevention of ischemic stroke. The purpose of this study is to find out the social and demographic characteristics of patients with acute ischemic stroke treated at Upendra Devkota Memorial National Institute of Neurological and Allied Sciences, a tertiary care hospital of Nepal. Methods: Data was collected from all acute ischemic stroke patients presenting to the hospital over a period of one year. The age, sex, medical history of hypertension and diabetes and history of smoking and alcohol consumption were recorded. Statistical analysis of data was performed using Microsoft EXCEL 2019. Result: Total 310 patients were studied, out of which two-thirds were male. The highest number of patients were within the age group of 60-80 years with the mean age being 60 years. Hypertension and diabetes were present in 67.42% and 28.53% of patients respectively. 43.93% of the patients smoked while 33.87% of the patients consumed alcohol. Conclusion: Identification of association between risk factors like age, sex, hypertension, diabetes mellitus, smoking and alcohol consumption must be the emphasis for targeted preventive action to decrease the increasing burden of ischemic stroke among developing countries.

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Study of serum uric acid level among stroke patients in a tertiary care hospital

Medpusle International Journal of Medicine ◽

10.26611/10211626 ◽

2020 ◽

Vol 16 (2) ◽

pp. 76-79

Author(s):

Chandrayya Achanna Kante ◽

Keyword(s):

Uric Acid ◽

Serum Uric Acid ◽

Uric Acid Level ◽

Acid Level ◽

Tertiary Care Hospital ◽

Serum Uric Acid Level ◽

Tertiary Care ◽

Care Hospital ◽

Stroke Patients

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Admission hyperglycemia an independent predictor of outcome in acute ischemic stroke: A longitudinal study from a tertiary care hospital in South India

Nigerian Journal of Clinical Practice ◽

10.4103/1119-3077.206368 ◽

2017 ◽

Vol 20 (5) ◽

pp. 573 ◽

Cited By ~ 5

Author(s):

MP Reddy ◽

SK Marulaiah ◽

M Basavegowda ◽

PKH Ramaswamy ◽

LS Adarsh

Keyword(s):

Ischemic Stroke ◽

Longitudinal Study ◽

Acute Ischemic Stroke ◽

South India ◽

Tertiary Care Hospital ◽

Independent Predictor ◽

Tertiary Care ◽

Care Hospital

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Ischemic stroke: Observations and analysis of stroke patients admitted in a tertiary hospital of Kathmandu

Journal of Kathmandu Medical College ◽

10.3126/jkmc.v8i2.28166 ◽

2019 ◽

Vol 8 (2) ◽

pp. 66-71

Author(s):

Dipesh Shakya ◽

Rabindra Shrestha ◽

Krishna Dhungana ◽

Raisha Kafle ◽

Sabnam Bhatta

Keyword(s):

Risk Factors ◽

Ischemic Stroke ◽

Carotid Artery ◽

Public Awareness ◽

Tertiary Care ◽

Care Hospital ◽

Stroke Patients ◽

Cross Sectional ◽

Carotid Artery Atherosclerosis ◽

Common Risk Factors

Background: Stroke is a disabling condition that has physical and mental impact on a patient’s life. Stroke is an important morbidity for low and middle income countries like Nepal. Hypertension, diabetes, smoking, and dyslipidemia are common risk factors in this regard and are inadequately controlled; mainly because of poor public awareness, inadequate infrastructure, lack of service and qualified manpower.Objectives: This study aims to provide insight into the epidemiology and risk factors in ischemic stroke patients.Methodology: A descriptive cross sectional study was conducted in 92 ischemic stroke patients at a tertiary care hospital Kathmandu Medical College and Teaching Hospital (KMCTH), Sinamangal, Nepal from December 2017 to June 2018. Consecutive sampling technique was used and data was collected from ischemic stroke patients above 14 years of age who were admitted in the Department of Neurology. Information regarding pre-morbid and morbid conditions, imaging findings as well as results was obtained from biochemical analysis of blood after taking consent from the patient or patient’s relative. Statistical Package for the Social Sciences Version 20 was used as a tool for statistical analysis.Results: Their mean age was 63.25 years with standard deviation of 16.45. Dyslipidemia was the most commonly found risk factor which was present in 77.2% of the subjects, followed by smoking (59.8%), presence of carotid artery atherosclerosis (59.8%), hypertension (50%), atrial fibrillation (26.1%) and diabetes mellitus(15.2%). Smoking was significant in males and heart disease was mostly seen in females.Conclusion: Dyslipidemia and smoking were the most common risk factors followed by carotid artery atherosclerosis. Patients with hypertension and dyslipidemia had higher incidence of stroke in both young and elderly group.

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